Pharmacology and Drug Treatment

Active Projects: 191

Project Investigator
 		All Topics Start date End date
Phase 1 Iontophoretic Delivery of Dexamethasone for Tx of Anterior Scleritis Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development, Pharmacology and Drug Treatment
First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial Nisha Acharya, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
ADalimumab Vs. conventional ImmunoSupprEssion for uveitis (ADVISE) Trial Nisha Acharya, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial Nisha Acharya, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
Iontophoresis Delivery of Dexamethason Phosphate for Non-Infectious, No-Necrotizing Anterior Scieritis, Phase I Dose-Varying Study Nisha Acharya, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
Replication fidelity mutants as attenuated poliovirus seeds for IPV production Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development, Pharmacology and Drug Treatment
RAPID: Ebola virus population structure, genetic diversity and evolution Raul Andino-Pavlovsky, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development, Pharmacology and Drug Treatment
2 year joint fellowship program in Clinical Pharmacy with Actelion Francesca Aweeka, PharmD Drug and Diagnostics Development, Pharmacology and Drug Treatment, Residencies, Fellowships, and Postdoctoral Training
Quality Assurance/Quality Control Program Francesca Aweeka, PharmD Pharmacology and Drug Treatment
LOC-IMPAACT Leadership Group Francesca Aweeka, PharmD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment, Women's Health, Pediatrics, Newborn and Infant Health, Systematic Reviews and Guideline Development
Clinical Pharmacology, Drug Action and Pharmacogenetics Esteban Burchard, MD, MPH Pharmacology and Drug Treatment, Residencies, Fellowships, and Postdoctoral Training
Pharmacogenomics of Bronchodilator Response in Minority Children with Asthma Esteban Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pharmacology and Drug Treatment, Pediatrics
Phase 2 Study, Safety of and Rate of Bacterial Clearance of Ceftobiprole Compared to Conventional Therapy in the Treatment of Subjects w/ Staphylococcus aureus Bacteremia Henry Chambers, MD Infectious Disease, Pharmacology and Drug Treatment
A Phase 2, Randomized, Open-Labeled Study on the Safety of and Rate of Bacterial Clearance of Ceftobiprole Compared to Conventional Therapy in the Treatment of Subjects w/ Staphylococcus aureus Bacteremia Henry Chambers, MD Infectious Disease, Pharmacology and Drug Treatment
Ceftobiprole vs. Daptomycin and Linezolid for Treatment of Experimental Staph. aureus Endocarditis in Rabbits Henry Chambers, MD Infectious Disease, Pharmacology and Drug Treatment
Tetrezolid vs. Daptomycin and Vancomycin for Treatment of Experimental Staphylococcus aureus Henry Chambers, MD Infectious Disease, Pharmacology and Drug Treatment
Protocol Development for a Phase 2 Study Evaluating the Safety and Feasibility of Ceftobiprole Compared to Conventional Therapy in the Treatment of Subjects w/ Staphylococcus aureus Bacteremia Henry Chambers, MD Infectious Disease, Pharmacology and Drug Treatment
IMPAACT Yr 08 P1077 CTU MOU #2 - St. Mary's Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Pharmacology and Drug Treatment, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
HPTN 084 Qualitative Substudy Funding Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Pharmacology and Drug Treatment
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Effectiveness, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, Policy and Standards of Care, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training
Targeting host autophagy for treating Mtb infections and synergizing with antibiotics in vivo Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Pharmacology and Drug Treatment
Enfuvirtide Intensification for Multi-Drug Resistant HIV Steven Deeks, MD Zoonosis, Emerging Disease, and Drug Resistance, HIV/AIDS, Pharmacology and Drug Treatment
San Francisco National Clinical Trial Center, ESPIRIT Steven Deeks, MD HIV/AIDS, Pharmacology and Drug Treatment
Short-Term Disulfiram Administration to Reverse Latent HIV Infection Steven Deeks, MD HIV/AIDS, Pharmacology and Drug Treatment
Interruption of Enfuvirtide in Patients Experiencing an Incomplete Virologic Response to Enfuvirtide-Based Combination Antiretroviral Regimen Steven Deeks, MD HIV/AIDS, Pharmacology and Drug Treatment
Immediate Salvage Therapy w/ Combination ART plus T-20 vs. A 16 Week Structured Treatment Interruption Followed by Combination Therapy plus T-20 Steven Deeks, MD HIV/AIDS, Pharmacology and Drug Treatment
Enfuvirtide Treatment Intensification in Patients with Multi-Drug Resistant HIV Steven Deeks, MD HIV/AIDS, Pharmacology and Drug Treatment
AIDS Clinical Trials Network (ACTG)-Deeks (Co-Vice Chair) A5296 Steven Deeks, MD HIV/AIDS, Noncommunicable and/or Chronic Disease, Pharmacology and Drug Treatment
The Impact of Early Antiretroviral Therapy on HIV Persistence and Inflammation Steven Deeks, MD HIV/AIDS, Pharmacology and Drug Treatment
Assessing Antiretroviral Exposure in Diverse Populations Monica Gandhi, MD, MPH HIV/AIDS, Pharmacology and Drug Treatment
Early Mortality in HIV-Infected Patients Starting Antiretroviral Therapy in Africa HIV/AIDS, Pharmacology and Drug Treatment
Systems Pharmacology Approaches to Understanding Drug Induced Weight Gain Pharmacology and Drug Treatment
Tenofovir Kidney Toxicity Study HIV/AIDS, Pharmacology and Drug Treatment
Role of ABCG2 in the disposition and anti-hyperuricemic effects of allopurinol Pharmacology and Drug Treatment
P.falciparum infection dynamics and transmission to inform elimination (INDIE) Bryan Greenhouse, MD Malaria, Pharmacology and Drug Treatment
Oral Drug Treatment for Enhanced Immune Control over HIV Replication HIV/AIDS, Pharmacology and Drug Treatment
ACE-Inhibitors to Decrease Lymphoid Fibrosis and the Size of the Latent Reservoir in Antiretroviral-Treated, HIV-infected Patients: A Randomized, Placebo-Controlled Study HIV/AIDS, Pharmacology and Drug Treatment
ADS-TCAD-P0206: TCAD Oral for Treatment of Influenza A Diane Havlir, MD Infectious Disease, HIV/AIDS, Opportunistic Infection, Pharmacology and Drug Treatment
Trial of Raltegravir Plus Darunavir/Ritonavir for Treatment-Naive HIV-1-Infected Subjects (ATCG A5262) Diane Havlir, MD HIV/AIDS, Pharmacology and Drug Treatment
SFBay CTU Diane Havlir, MD HIV/AIDS, Pharmacology and Drug Treatment
Novel Strategies to Prevent Malaria and Improve Maternal-Child Health in Africa (PROMOTE) Diane Havlir, MD HIV/AIDS, Malaria, Pharmacology and Drug Treatment, Women's Health, Pediatrics, Newborn and Infant Health
Task Order # 9: Supplement to SSS A5272 Diane Havlir, MD HIV/AIDS, Pharmacology and Drug Treatment
Task Order Supplement to A5267 Diane Havlir, MD HIV/AIDS, Tuberculosis, Pharmacology and Drug Treatment
Task Order A5303: Trial to Determine the Bone, Immunologic, Virologic, and Neurocognitive Effects of a Novel Maraviroc-Containing Antiretroviral Regimen in Treatment-Naive Patients Infected with R5-Tropic HIV-1 Diane Havlir, MD HIV/AIDS, Pharmacology and Drug Treatment
Effect of low dose methotrexate on endothelial function and inflammation in HIV - A5314 Diane Havlir, MD HIV/AIDS, Pharmacology and Drug Treatment
Study of Three NNNRTI-Sparing Antiretroviral Regimens for Treatment-Naive HIV-1-Infected Volunteers (ACTG A5257) Diane Havlir, MD HIV/AIDS, Pharmacology and Drug Treatment
Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection HIV/AIDS, Cardiovascular Disease, Pharmacology and Drug Treatment
International Randomized, Controlled Phase 3 Trial of DB289 Versus Trimethoprim-Sulfamethoxazole for Treatment of Acute Pneumocystis jiroveci Pneumnia (PCP) in Patients with HIV/AIDS Laurence Huang, MD HIV/AIDS, Opportunistic Infection, Pharmacology and Drug Treatment
Early Antiretroviral Therapy in Resource Limited Settings in Patients with High CD4+ Cell Counts Vivek Jain, MD HIV/AIDS, Pharmacology and Drug Treatment
HIV Emergence of Drug Resistance Zoonosis, Emerging Disease, and Drug Resistance, HIV/AIDS, Pharmacology and Drug Treatment
AI452-020-0092: Phase 3 Blinded Randomized Study of Peginterferon Lambda-1a and Ribavirin Compared to Peginterferon Alfa-2a and Ribavirin, Each Administered with Telaprevir in Subjects with Genotype-1 Chronic Hepatitis C who are Treatment-naïve or Re Mandana Khalili, MD Infectious Disease, Pharmacology and Drug Treatment
Phase III Trial of the Efficacy and Safety of Clevudine Compared With Adefovir at Weeks 48 and 96 in Nucleoside Treatment-Naïve Patients With HBeAg Negative Chronic Hepatitis Due to Hepatitis B Virus Mandana Khalili, MD Infectious Disease, Pharmacology and Drug Treatment
GS-US-367-1172: A Phase 3, Global, Multicenter, Randomized, Open-Label Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 Fixed-Dose Combination for 8 Weeks Compared to Sofosbuvir/Velpatasvir for 12 Weeks in Direct-Acting Mandana Khalili, MD Infectious Disease, Pharmacology and Drug Treatment
A Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Adults with Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection Mandana Khalili, MD Infectious Disease, Pharmacology and Drug Treatment
Steroids and Cross-linking for Ulcer Treatment (SCUT II) Thomas Lietman, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
AVENIR: Assessing the impact of azithromycin on child mortality in Niger Thomas Lietman, MD Zoonosis, Emerging Disease, and Drug Resistance, Pharmacology and Drug Treatment, Pediatrics, Newborn and Infant Health, Health Economics and Effectiveness
The Steroids for Corneal Ulcers Trial Thomas Lietman, MD Infectious Disease, Eye Disease and Blindness, Pharmacology and Drug Treatment
What is the Appropriate Frequency and Duration of Mass Azithromycin Thomas Lietman, MD Neglected Tropical Diseases (NTDs), Eye Disease and Blindness, Pharmacology and Drug Treatment
Research to Programs for Trachoma Elimination Thomas Lietman, MD Infectious Disease, Eye Disease and Blindness, Pharmacology and Drug Treatment, Epidemiology and Surveillance
Mycotic Ulcer Treatment Trial Thomas Lietman, MD Infectious Disease, Neglected Tropical Diseases (NTDs), Eye Disease and Blindness, Pharmacology and Drug Treatment
TANA II Thomas Lietman, MD Infectious Disease, Neglected Tropical Diseases (NTDs), Eye Disease and Blindness, Pharmacology and Drug Treatment, Epidemiology and Surveillance
P-S RPB - Assessing Corneal Ulcer Prevention with a Community-Randomized Trial Thomas Lietman, MD Neglected Tropical Diseases (NTDs), Eye Disease and Blindness, Pharmacology and Drug Treatment
Eliminating Trachoma with Repeat Mass Drug Treatment Thomas Lietman, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
GS-US-380-4030: A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Switching from a Regimen of Dolutegravir and Either Emtricitabine/Tenofovir Alafenamide or Emtricitabine/Tenofovir Disoproxil Fumarate to a Fixed Dose Co Anne Luetkemeyer, MD Infectious Disease, Pharmacology and Drug Treatment
MK-3682B-037-00A: Phase 3 Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-3682B (Grazoprevir/Ruzasvir/Uprifosbuvir) in Participants with Chronic Hepatitis C Virus Genotype 3 Infection Anne Luetkemeyer, MD Infectious Disease, Pharmacology and Drug Treatment
A Multicenter, Randomized, Double-Blind, Placebo Controlled Trial of a Novel CCR5 Antagonist, UK427,857, for the Treatment of Antiretroviral-Experienced HIV-1-Infected Subjects Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
Tibotec TMC125-C214: Early Access of TMC125 in Combination with Other Antiretrovirals in Treatment-Experienced HIV-1 Infected Subjects with Limited Treatment 0ptions Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
A phase III trial to investigate the efficacy, tolerability & safety of TMC125 as part of an ART including TMC114/RTV and an investigator-selected OBR in HIV-1 infected subjects w/ limited to no treatment options Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
Tobira 652-2-202 Pre-Clinical Trial Cost Agreement Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
GSK_201585: Phase III, randomized, multicenter, parallel-group, non inferiority, open-label study evaluating the efficacy, safety, & tolerability of switching to long-acting cabotegravir plus long acting rilpivirine from current INI,NNRTI, or PI-based ART Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
A Phase 3, Open-Label Study to Investigate the Efficacy and Safety of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 weeks in Subjects with Chronic HCV and HIV-1 Coinfection Anne Luetkemeyer, MD Infectious Disease, HIV/AIDS, Pharmacology and Drug Treatment
A Phase III Randomized Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172/MK-8742 in Treatment-Naive Subjects with Chronic HCV GT1, GT4, GT5, and GT6 Infection who are on Opiate Substitution Therapy Anne Luetkemeyer, MD Infectious Disease, HIV/AIDS, Pharmacology and Drug Treatment
Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267 and ABT-333 Coadministered with Ribavirin in Adults with Genotype 1 Chronic HCV and HIV Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
GS_US_342-1139: Phase 3, Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks with Sofosbuvir and Ribavirin for 12 Weeks in Subjects with Chronic Genotype 2 HCV Infecti Anne Luetkemeyer, MD Infectious Disease, Pharmacology and Drug Treatment
Entecavir Intensification for HIV-HBV Coinfected subjects with persistent HBV viremia Anne Luetkemeyer, MD Infectious Disease, HIV/AIDS, Pharmacology and Drug Treatment
Pfizer A4001027: Observational Phase Extension Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
M14-730 (EXPEDITION-2): A Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Adults with Chronic Hepatitis C Virus (HCV) Genotype 1-6 Infection and Human Immunodeficiency Virus-1 (HIV-1) Co-Infection Anne Luetkemeyer, MD Infectious Disease, HIV/AIDS, Pharmacology and Drug Treatment
ASN100-201: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety and Efficacy of a Single Dose of ASN100 for the Prevention of Staphylococcus aureus Pneumonia in Heavily Colonized, Mechanically Ventilated Subjects Anne Luetkemeyer, MD Infectious Disease, Pharmacology and Drug Treatment
Gilead GS-US-236-0102 Anne Luetkemeyer, MD HIV/AIDS, Pharmacology and Drug Treatment
Evaluation of technetium Tc 99m tilmanocept (Lymphoseek) Localization, Retention, and Distribution in Primary Cutaneous Kaposi's Sarcoma (KS) and Lymphatic Drainage from KS Lesions by SPECT and SPECT/CT Imaging Toby Maurer, MD HIV/AIDS, Cancer/Oncology, Pharmacology and Drug Treatment
Role of Buprenorphine in Improving Clinical Care in Opioid Addiction and HIV HIV/AIDS, Pharmacology and Drug Treatment, Substance Abuse
Optimization of Cysteine Protease Inhibitors Targeting Trypanosoma Brucei Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Targeting Cysteine Proteases--Antiparasitic Chemotherapy Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Transcriptional Responses of Parasite and Host during Intestinal Colonization and Invasion by Entamoeba histolytica Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
High Throughput Assay for Screening Compounds Against T. Brucei Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Host Protein Degradation by Schistosome Parasites Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Misoprostol for Prevention or Early Treatment Suellen Miller, PhD, CNM, MHA Pharmacology and Drug Treatment, Labor and Delivery
Tuberculosis Trials Consortium (TBTC) Payam Nahid, MD, MPH Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Thai Red Cross S&S, HPV TA008 Joel Palefsky, MD Infectious Disease, Sexually Transmitted Infections (STIs), Cancer/Oncology, Pharmacology and Drug Treatment
The Impact of Anogenital Human Papillomavirus in the Transmission of HIV in Urban Brazil: Phase II Study Joel Palefsky, MD Infectious Disease, Pharmacology and Drug Treatment
Pharmacogenomics of Antimalarial Drugs Sunil Parikh, MD, MPH Malaria, Genetics, Pharmacology and Drug Treatment
Vision to Discover New Treatments for Parkinson's and Other Neurodegenerative Diseases Pharmacology and Drug Treatment, Neurology and Mental Health
Expanded Access to MGAWN1 in Subjects with Suspected West Nile Neuroinvasive Disease; Substantial Exposure, or Infection and a Compromised Immune System Jeffrey Ralph, MD Zoonosis, Emerging Disease, and Drug Resistance, Pharmacology and Drug Treatment
Medical Pharmacy Consultation Team E. Michael Reyes, MD, MPH HIV/AIDS, Pharmacology and Drug Treatment
Medical Pharmacy Consultation Team E. Michael Reyes, MD, MPH HIV/AIDS, Pharmacology and Drug Treatment
Pharmacodynamics of Antimalarial Chemoprevention Philip J. Rosenthal, MD Malaria, Pharmacology and Drug Treatment
Protocol AI463-189-004: A Comparative Study of the Antiviral Efficacy and Safety of Entecavir (ETV) HIV/AIDS, Pharmacology and Drug Treatment
Phase 2, Open-Label, Multicenter, Multi-cohort, Single-Arm Study to Investigate the Safety and Efficacy of Sofosbuvir + Ribavirin in Adolescents and Children with Genotype 2 or 3 Chronic HCV Infection Infectious Disease, Pharmacology and Drug Treatment
A Two-Part, Open-Label, Single-Arm Phase 1/2 Study of Safety, Pharmacokinetics, and Efficacy of Telaprevir in Combination with Peginterferon alfa-2b and Ribavirin in Pediatric Subjects Aged 3 to 17 Infected With Genotype 1 Hepatitis C Virus Infectious Disease, HIV/AIDS, Pharmacology and Drug Treatment, Pediatrics
Protocol Development Co-Chair for Phase I/II, Multi-Center, Open-Label Pharmacokinetic, Safety, Tolerability and Antiviral Activity of GSK 1349572, a novel integrase inhibitor, in combination regimens in HIV-1 Infected Infants, Children & Adolescents Theodore Ruel, MD HIV/AIDS, Pharmacology and Drug Treatment, Pediatrics, Adolescent Health
Quality of Sleep in HIV-Infection: Association with Treatment and Adherence Parya Saberi, PharmD HIV/AIDS, Pharmacology and Drug Treatment, Treatment Adherence
Genome-Wide Association Study to Examine Genes Associated with An Increased Risk of Febrile Seizure in Children Following Measles-Containing Vaccines Mark Seielstad, PhD Infectious Disease, Transfusion Medicine, Immunology, Pharmacology and Drug Treatment, Pediatrics, Epidemiology and Surveillance
Tenofovir in Pregnancy (TIP) Study HIV/AIDS, Pharmacology and Drug Treatment, Women's Health, Newborn and Infant Health
Preventing the Neonatal Narcotic Abstinence Syndrome (NAS) Juan Vargas, MD Pharmacology and Drug Treatment, Newborn and Infant Health, Substance Abuse
CHRP Disparities Initiative: UCSF CFAR Conference Award Paul Volberding, MD HIV/AIDS, Drug and Diagnostics Development, Pharmacology and Drug Treatment
UCSF-GIVI Center for AIDS Research (CFAR) Paul Volberding, MD HIV/AIDS, Tuberculosis, Malaria, Cancer/Oncology, Cardiovascular Disease, Drug and Diagnostics Development, Immunology, Pharmacology and Drug Treatment, Neurology and Mental Health, Trauma and PTSD, Women's Health, Pediatrics, Implementation and Behavioral Science, Training and Capacity Building, Training International Scholars and Clinicians
Financial Impact of the Current and Alternative Pricing Practices for Compounded, Co-packaged, and Over-the-Counter drugs and Medical Foods within the California Workers' Compensation System: Non-Formulary Impact if Pharmacy or Physician Dispensed Leslie Wilson, PhD, MS Pharmacology and Drug Treatment, Health Economics and Effectiveness, Access or Barriers to Care
Navigating the Scientific Evidence to Ensure Prevention Tracey Woodruff, PhD, MPH Occupational and Environmental Disease, Pharmacology and Drug Treatment, Systematic Reviews and Guideline Development, Epidemiology and Surveillance
Clinical Pharmacology, Drug Action and Pharmacogenetics Neal Benowitz, MD Drug and Diagnostics Development, Pharmacology and Drug Treatment
A Pilot Study of FOLFOX in Combination with Bevacizumab in Patients with Advanced Neuroendocrine Tumors Cancer/Oncology, Pharmacology and Drug Treatment
Improving Medicines Use for Noncommunicable Diseases in Low Resource Settings Lisa Bero, PhD Pharmacology and Drug Treatment, Access or Barriers to Care, Policy and Standards of Care, Systematic Reviews and Guideline Development
Phase II Study of 7 Days On/7 Days Off Temozolomide in Patients with High Grade Glioma Cancer/Oncology, Pharmacology and Drug Treatment
JBAL: A Phase 2 Study of LY2157299 Monohydrate Monotherapy or LY2157299 Monohydrate plus Lomustine Therapy compared to Lomustine Monotherapy in Patients with Recurrent Glioblastoma Cancer/Oncology, Pharmacology and Drug Treatment
Efficacy and Safety of Eraxis/Ecalta (Anidulafungin) Compared to Cancidas (Caspofungin) in Patients with Candida Deep Tissue Infection: A Phase 4 Study Infectious Disease, HIV/AIDS, Opportunistic Infection, Pharmacology and Drug Treatment
WSA-CS-003: Open Label Study of Isavuconazole in the Treatment of Patients with Aspergillosis and Renal Impairment or of Patients with Invasive Fungal Disease Caused by Rare Molds, Yeasts or Dimorphic Fungi Infectious Disease, Opportunistic Infection, Pharmacology and Drug Treatment
A Randomized, Double-Blind Study to Assess the Efficacy and Safety of Prophylactic Use of Maribavir Versus Oral Ganciclovir for the Prevention of Cytomegalovirus Disease in Recipients of Orthotopic Liver Transplants Opportunistic Infection, Pharmacology and Drug Treatment
Phase IV Open-Label, Non-comparative Trial of IV Anidulafungin followed by Oral Azole Therapy for the Treatment of Candidemia and Invasive Candidiasis HIV/AIDS, Opportunistic Infection, Pharmacology and Drug Treatment
A8851009: A Prospective, Randomized Trial Comparing the Efficacy of Anidulafungin and Voriconazole in Combination to that of Voriconazole Alone When Used For Primary Therapy of Proven or Probable Invasive Aspergillosis Opportunistic Infection, Pharmacology and Drug Treatment
Protocol # ADMA-001: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Ranging Trial Evaluating the Safety and Efficacy of RI-001 in Medically Immunosuppressed Respiratory Syncytial Virus (RSV) Infected Patients at Risk of Lower Tract RSV HIV/AIDS, Opportunistic Infection, Pharmacology and Drug Treatment
Misoprotsol versus Placebo with Laminaria for Cervical Ripening before Late Second Trimester Abortion Philip Darney, MD, MS Pharmacology and Drug Treatment, Family Planning
Phase 3, Randomized, Multi-Center, Open-Label Study of a Levonorgestrel-Releasing Intrauterine System (20 Mcg/Day) and Mirena® for Long-Term, Reversible Contraception up to Five Years Philip Darney, MD, MS Pharmacology and Drug Treatment, Family Planning
Multi-center, open-label, uncontrolled study to assess contraceptive efficacy and safety of Mirena during extended use beyond 5 years in women 18 to 35 years of age including a subgroup evaluation of treatment effect on heavy menstrual bleeding Philip Darney, MD, MS Pharmacology and Drug Treatment, Women's Health, Family Planning
Implantable multi-analyte sensors for the continuous monitoring of body chemistries Tejal Desai, PhD Pharmacology and Drug Treatment
Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) Jacque Duncan, MD Eye Disease and Blindness, Pharmacology and Drug Treatment
Statistical methods for clinical trials of novel PrEP agents David Glidden, PhD HIV/AIDS, Pharmacology and Drug Treatment, Systematic Reviews and Guideline Development
Comparison of Pharmacologic Markers of Exposure to HIV Pre-Exposure Prophylaxis David Glidden, PhD HIV/AIDS, Pharmacology and Drug Treatment
The Use of Nelfinavir During Acute or Early HIV Infection - Safety, Tolerability, Durablilty and Resistance HIV/AIDS, Pharmacology and Drug Treatment
Task Order #1 RAMPART Study - Neurological Emergencies Treatment Trials Pharmacology and Drug Treatment, Neurology and Mental Health
Task Order #3: Protect II Study - Neurological Emergencies Treatment Trial Pharmacology and Drug Treatment, Neurology and Mental Health, Trauma and PTSD
Ultrasensitive Monitoring of HIV-1 Drug Resistance Reversion Following Transmission with Drug Resistant Virus HIV/AIDS, Pharmacology and Drug Treatment, Women's Health, Newborn and Infant Health
PAAR4Kids-Pharmacogenomics Research Network Cancer/Oncology, Genetics, Pharmacology and Drug Treatment
Botulinum neurotoxin (BoNT) Collaboration Occupational and Environmental Disease, Pharmacology and Drug Treatment
An Open-Label, Multicenter Study Evaluating the Safety and Tolerability of Once-Daily Oral Aripiprazole in Children and Adolescents with Tourette's Disorder Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health
A Phase 4, Randomized, Double-Blind, Multicenter, Parallel-Group, Active-Controlled, Forced-Dose Titration, Safety and Efficacy Study of SPD489 (VYVANSE®) Compared with OROS-MPH (CONCERTA®) with a Placebo Reference Arm, in Adolescents Aged 13-17 Year Pharmacology and Drug Treatment, Neurology and Mental Health
Phase 4, Parallel Group, Active-Controlled, Dose-Optimization Study of SPD489 (Vyvanse) Compared with OROS-MPH (Concerta) with a Placebo Reference Arm, in Adolescents 13-17 with Attention-deficit/Hyperactivity Disorder Pharmacology and Drug Treatment
Phase 1b, Open-Label, Dose-Escalation Study of the Safety and Pharmacology of MEGF0444A, A Humanized 1gG1 Antibody in Combination with Bevacizumab with or without Paclitaxel in Patients with Locally Advanced or Metastatic Solid Tumors Cancer/Oncology, Pharmacology and Drug Treatment
Phase 1 Open-Label First-in-Human Dose-Escalating Safety and Tolerability Study Evaluating Subcutaneous Administration of Andes-1537 for Injection in Patients With Advanced Unresectable Malignancies That Are Refractory to All Standard Cancer/Oncology, Pharmacology and Drug Treatment
BEACON Study (BrEAst Cancer Outcomes with NKTR-102): Phase 3 Study of NKTR-102 versus Treatment of Physician's Choice (TPC) in Patients with Locally Recurrent or Metastatic Breast Cancer Previously Treated with Anthracycline, a Taxane and Capecitabine Cancer/Oncology, Pharmacology and Drug Treatment, Women's Health
Genetic Determinants of Capecitabine Toxicity Genetics, Pharmacology and Drug Treatment
Nonlinear Mixed Effects Modeling of Rifapentine Pharmacokinetics Rada Savic, PhD Tuberculosis, Pharmacology and Drug Treatment
Development of Rectal Enema As Microbicide (DREAM) Rada Savic, PhD HIV/AIDS, Pharmacology and Drug Treatment
Mechanism-Based Integrative Pharmacology Model for Tuberculosis Rada Savic, PhD Tuberculosis, Pharmacology and Drug Treatment
Impact of Pregnancy on Tuberculosis Rada Savic, PhD Tuberculosis, Pharmacology and Drug Treatment, Women's Health, Labor and Delivery, Newborn and Infant Health
Identifying Optimal Treatment Strategies for Tuberculosis Treatment Rada Savic, PhD Tuberculosis, Pharmacology and Drug Treatment
A Randomized Controlled Trial Evaluating Locally Administered Gentamicin in the Prevention of Deep Infection after Open Tibial Shaft Fractures in Tanzania David Shearer, MD Opportunistic Infection, Surgery and Anesthesia, Pharmacology and Drug Treatment
A Specific Mechanism for non-specific inhibition Pharmacology and Drug Treatment
Randomized Controlled Trial of 6% Cellulose Sulfate Gel and the Effect on Vaginal HIV Transmission Ariane Van der Straten, PhD, MPH Sexually Transmitted Infections (STIs), HIV/AIDS, Pharmacology and Drug Treatment
SOCRATES - Acute Stroke Or Transient Ischaemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes Cardiovascular Disease, Pharmacology and Drug Treatment
Optimizing Management of Transient Ischemic Attacks Cardiovascular Disease, Pharmacology and Drug Treatment
CASTIA Neurological Core Imaging Lab (NCIL) Cardiovascular Disease, Pharmacology and Drug Treatment, Neurology and Mental Health
Antiplatelet Therapy for Ischemic Stroke and Transient Ischemic Attack in U.S. Community Hospitals Cardiovascular Disease, Pharmacology and Drug Treatment
Phase III Clinical Trial "Platelet Oriented Inhibition in New Tia" - Drug: Plavix Cardiovascular Disease, Pharmacology and Drug Treatment
MAPS: Matrix And Platinum Science, A Prospective, Randomized, Multicenter, Trial Investigating Matrix2 tm and GDC? Coils for the treatment of intracranial saccular aneurysms Trial Cardiovascular Disease, Pharmacology and Drug Treatment
A Phase III Multicenter Randomized Study of the Biological and Clinical Efficacy of Subcutaneous Recombinant, Human Interleukin-2 in HIV-Infected Patients with Low CD4+ Counts (SILCAAT) James Kahn, MD, MPH HIV/AIDS, Pharmacology and Drug Treatment, Health Economics and Effectiveness
Provider Practices in Non-Malarial Fevers: A Pilot Study in Malawi Kimberly Baltzell, RN, PhD, MS Drug and Diagnostics Development, Pharmacology and Drug Treatment
Life After Pediatric Sepsis Evaluation, LAPSE Drug and Diagnostics Development, Pharmacology and Drug Treatment, Pediatrics
Development of Regulatory T-Cells for Treatment of Autoimmune Disease Jeffrey Bluestone, PhD Immunology, Pharmacology and Drug Treatment
Biotest Analysis for HCMV Infection in Placentas Lenore Pereira, PhD Infectious Disease, Pharmacology and Drug Treatment, Women's Health, Newborn and Infant Health
Pharmacokinetics and tolerability of adjunctive linezolid for the treatment of tuberculous meningitis Felicia Chow, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Selectively targeting delta opioid receptor subtypes to control drinking behavior Jennifer Whistler, PhD Pharmacology and Drug Treatment, Substance Abuse
Therapeutic Effects of Pharmacological Manipulation of Intracellular Nitric Oxide Levels in Cardiovascular Disease Cardiovascular Disease, Pharmacology and Drug Treatment
The No One Waits (NOW) Study: Acceptability, feasibility, and effectiveness of a community based on-site point-of-diagnosis HCV treatment study Meghan Morris, PhD, MPH Infectious Disease, Sexually Transmitted Infections (STIs), Pharmacology and Drug Treatment, Epidemiology and Surveillance
Building evidence to support safe radical cure for P. vivax in Lao PDR: operational research in collaboration with UCSF Adam Bennett, PhD, MA Malaria, Pharmacology and Drug Treatment
Pre-CTA A Double-blind, Randomized and Placebo-controlled Study to Evaluate the Safety and Efficacy of T89 in Preventing Acute Mountain Sickness (AMS) During Rapid Ascent Jeffrey Sall, PhD, MD Occupational and Environmental Disease, Pharmacology and Drug Treatment
Consultancy to develop a global demand forecasting for malaria rapid diagnostic tests, artemisinin-based combination therapies and artemisinin Colin Boyle, MPP, MBA Pharmacology and Drug Treatment, Access or Barriers to Care
Can Risedroneate & PTH Reverse Glucocorticoid-Induced Osteoporosis Lisa Chen, MD Pharmacology and Drug Treatment
A phase II study of intravenous T900607-sodium in subject with previously treated ovarian cancer Lisa Chen, MD Pharmacology and Drug Treatment
Study of the Efficacy of Glucosamine/Chondroitin Sulfate in Knee Osteoarthritis - Ancillary Structural Study Lisa Chen, MD Pharmacology and Drug Treatment
Interventional Study to Assess the Safety and Efficacy of Pharmaceutical Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Lennox-Gastaut Syndrome Pharmacology and Drug Treatment, Neurology and Mental Health
Allosteric Inhibition of a Family of Proteolytic Enzymes Charles Craik, PhD Immunology, Pharmacology and Drug Treatment
A Phase 1b Open-label Study to Evaluate the Safety and Tolerability of MEDI4736 in Combination with Tremelimumab in Subjects with Advanced Non-small Cell Lung Cancer Cancer/Oncology, Pharmacology and Drug Treatment
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin plus Olaratumab versus Doxorubicin plus Placebo in Patients with Advanced or Metastatic Soft Tissue Sarcoma Cancer/Oncology, Pharmacology and Drug Treatment
Phase III Global Study of MEDI4736 in Combination with Tremelimumab Therapy or MEDI4736 Monotherapy vs Standard of Care Platinum-Based Chemotherapy in First-Line Treatment of Patients with Locally Advanced or Metastatic Non Small-Cell Lung Cancer Cancer/Oncology, Pharmacology and Drug Treatment
A Phase 2 Proof-of-Concept Study of the Combination of ACP-196 and Pembrolizumab in Subjects with Advanced Non-small Cell Lung Carcinoma Cancer/Oncology, Pharmacology and Drug Treatment
Actelion - AC-065A304 Multicenter, open-label, single-group study to assess the tolerability and the safety of the TRANSITion from inhaled tresprostinil to oral selexipag in patients with pulmonary arterial hypertension 20150803 Cardiovascular Disease, Pharmacology and Drug Treatment
Trial of Pirfenidone in CKD, TOP CKD Michael Shlipak, MD Pharmacology and Drug Treatment
Management Sciences for Health Director of Capacity Building and Performance Improvement Tina Brock, MS, EdD Pharmacology and Drug Treatment, Policy and Standards of Care, Systematic Reviews and Guideline Development, Training and Capacity Building
Associate Dean for Global Health and Educational Innovations UCSF School of Pharmacy Tina Brock, MS, EdD Pharmacology and Drug Treatment, Health Economics and Effectiveness, Access or Barriers to Care, Policy and Standards of Care, Health Systems Strengthening
The inverse association between cancer and Alzheimers disease: comparing spurious and causal explanations to illuminate the causes of Alzheimers disease Maria Glymour, ScD, MS Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment
Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult and Elderly Hospitalized Patients With Influenza A Infection Steven Stoltz, MD Pharmacology and Drug Treatment
Phase 3 Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate Efficacy & Safety of Pimodivir in Combination With Standard-of-care Treatment in Adolescent, Adult, and Elderly Hospitalized Patients With Influenza A Infection Steven Stoltz, MD Infectious Disease, Pharmacology and Drug Treatment
Development and validation for an HPLC-UV multiplex assay for therapeutic drug monitoring of antiretroviral drugs in Uganda Allan Buzibye, Bsc HIV/AIDS, Pharmacology and Drug Treatment
Pediatric drug dosing in very low resource environments Malnutrition, Micronutrients, Food Insecurity, Pharmacology and Drug Treatment, Immigration and Migration, Systematic Reviews and Guideline Development
Antimalarial drugs in Ugandan populations Melissa Conrad, PhD HIV/AIDS, Malaria, Drug and Diagnostics Development, Pharmacology and Drug Treatment, Pediatrics
he Efficacy of Various Antibiotics at Targeting Wolbachia for the Treatment of Lymphatic Filariasis Emma Gunderson, MS Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Pain Management in Clinic & Community Kelly Knight, PhD Pharmacology and Drug Treatment
Kebele Elimination of Trachoma for Ocular Health Catherine Oldenburg, ScD, MPH Eye Disease and Blindness, Pharmacology and Drug Treatment, Epidemiology and Surveillance
Building Evidence for Advancing New Treatment For XDR/XDR-TB (BEAT TUBERCULOSIS) Study Patrick Phillips, PhD, MS, MA Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Pharmacology and Drug Treatment
Modernization of Phase 3 TB Clinical Trial Endpoints Patrick Phillips, PhD, MS, MA Tuberculosis, Pharmacology and Drug Treatment, Systematic Reviews and Guideline Development
Clinical trials to improve the treatment of drug-sensitive and MDR-TB Patrick Phillips, PhD, MS, MA Tuberculosis, Immunology, Pharmacology and Drug Treatment
PK/PD modeling to optimize prevention in African children Erika K. Wallender, MD Malaria, Pharmacology and Drug Treatment

Active Investigators: 1