Department of Laboratory Medicine

Active Projects: 20

Project Investigator All Organizations Start date End date
Mesenchymal Stem Cells for the Prevention of Acute Respiratory Distress Syndrome after Pulmonary Contusion and Hemorrhagic Shock Department of Laboratory Medicine
Dried Plasma to Improve Outcomes in Polytrauma, Hemorrhage, and Trauma-Associated Sepsis (TAS): Novel Solutions for the Prolonged Field Care Environment Department of Laboratory Medicine
Development of a Host Biomarker Assay for the Diagnosis of Acute Lyme disease and Post-Treatment Lyme Disease Syndrome Jerome Bouquet, PhD Department of Laboratory Medicine
Identification of diagnostic and prognostic host biomarkers of Zika virus infection by transcriptome profiling Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Pre-B Cell Receptor Signaling in Acute Lymphoblastic Leukemia Markus Muschen, MD, PhD Department of Laboratory Medicine
Stem Cells for the Prevention of Inflammatory Complications of Severely Injured Trauma Patients Department of Laboratory Medicine
Modulation of Pulmonary Vascular Permeability and Inflammation by Mesenchymal Stem Cells (MSCs) in Hemorrhagic Shock Department of Laboratory Medicine
Platelets Modulate Vascular Stability: Assessing the Biological Properties and Function of Apheresis Platelets Stored at 22C vs. 4C Department of Laboratory Medicine
Regulation of Innate Immune Signaling by Lyn Kinase Clifford Lowell, MD, PhD Department of Laboratory Medicine
Effects of blood conservation and donor characteristics on transfused patient outcomes in a large community hospital network Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine
Master Agreement: Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - International Sites Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine
Master Agreement: Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - Domestic Sites Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine
Bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples Taylor Sittler, MD Department of Laboratory Medicine
International Training in Transfusion Medicine Mike Busch, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Transfusion science and HIV, HTLV, and dengue research in Brazil Philip Norris, MD IGHS Faculty Affiliate, Department of Laboratory Medicine
Transfusion medicine and Blood safety: Policy, Diagnostics and Standards development Mike Busch, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Prothrombin Complex Concentrate for Prolonged Field Care of War Casualties Department of Laboratory Medicine
Pan-Genomic Approaches for Comprehensive Blood Screening of Novel or Emerging Infectious Agents Charles Chiu, MD, PhD Department of Laboratory Medicine
A Combined Pathogen-Host Sequencing Assay for Diagnosis of Lyme and Other Tickborne Infections Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Research training in HIV-related transfusion medicine and hematology in South Africa Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine

Archived Projects: 77

Project Investigator All Organizations Start date End date
Retrovirus Epidemiology Donor Study (REDS) Edward Murphy, MD, MPH Department of Laboratory Medicine
Use of r-hGh to Enhance Thymopoiesis and to Facilitate Immune Restoration in Individuals Infected with HIV-1 J. McCune, MD, PhD Department of Laboratory Medicine
Pathophysiology of HTLV-I and HTLV-II Infection Edward Murphy, MD, MPH Department of Laboratory Medicine
XI International Conference on Human Retrovirology: HTLV Edward Murphy, MD, MPH Department of Laboratory Medicine
Natural History of Acute and Chronic HCV in Blood Donors Edward Murphy, MD, MPH Department of Laboratory Medicine
Clinical Epidemiology of HTLV-I and HTLV-II Infection Edward Murphy, MD, MPH Department of Laboratory Medicine
Pathophysiology of HTLV-I and HTLV-II Infection Edward Murphy, MD, MPH Department of Laboratory Medicine
Sangre Segura: An Epidemiological Study of Blood Transfusion Safety in the Mexico-U.S. Border Region Edward Murphy, MD, MPH Department of Laboratory Medicine
Targeting Cysteine Proteases--Antiparasitic Chemotherapy Department of Laboratory Medicine, Center for Discovery and Innovation in Parasitic Disease (CDIPD)
Poverty, Gender Inequities, & Sexual/Reproductive Health: An Impact Evaluation of a Combined Economic & Psycho-social Intervention in southern Tanzania Julius Schachter, PhD Department of Laboratory Medicine
Mechanisms of Leukocyte Integrin Signaling Clifford Lowell, MD, PhD Department of Laboratory Medicine
Identification of Viruses in an Asthma Cohort Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Metagenomics for Identification of Infectious Triggers of KLS Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Retrovirus Epidemiology Donor Study-II (REDS-II) Central Laboratory Mark Seielstad, PhD Department of Laboratory Medicine
Research Training in International Transfusion Safety Edward Murphy, MD, MPH Department of Laboratory Medicine
Virus Detection Using Microarrays and Characterization of a Novel Cardiovirus Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Retrovirus Epidemiology Donor Study-II REDS-II International Component - Blood Center Edward Murphy, MD, MPH Department of Laboratory Medicine
XV International Conference on Human Retrovirology: HTLV and Related Viruses Edward Murphy, MD, MPH Department of Laboratory Medicine
Point-of-Care Diagnostics for STI and UTI Julius Schachter, PhD Department of Laboratory Medicine
To Discover and Characterize Novel Viruses in Cancer Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Viral Discovery in Human and Animal Samples Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Evaluation of Abbott RealTime CT/NG for the Detection of C. trachomatis & N. gonorrhoeae from the Pharynx, Rectum & Urethra of MSM Julius Schachter, PhD Department of Laboratory Medicine
Using Pan-Pathogen Microarrays and Deep Sequencing to Search for the Cause of Southern Tick-Associated Rash Illness (STARI) Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Evaluation of a Novel Automated PCR Method for Infectious Disease Diagnostics Steve Miller, MD, PhD Department of Laboratory Medicine
Retrovirus Epidemiology and Donor Evaluation Study-III (REDS-III) - International Sites Edward Murphy, MD, MPH Department of Laboratory Medicine
A Rapid Pan-Viral Microarray Diagnostic for Category A-C Biodefense Pathogens Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - Central Laboratory Mark Seielstad, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Pre-B Cell Receptor Signaling in Acute Lymphoblastic Leukemia Markus Muschen, MD, PhD Department of Laboratory Medicine
Targeted Testing for Toxic Chemicals in People Alan Wu, PhD Department of Laboratory Medicine
Evaluation of BD Vacutainer SST Ultra and Serum Ultra Blood Collection Tubes for Selected Therapeutic Drugs (Sample Collection) Alan Wu, PhD Department of Laboratory Medicine
Determination of the Biological Variability (BV) of the Hevylite (HL) Assays. Alan Wu, PhD Department of Laboratory Medicine
TO#1: Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - International Sites Edward Murphy, MD, MPH Department of Laboratory Medicine
Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - Domestic Hub Edward Murphy, MD, MPH Department of Laboratory Medicine
Comprehensive Diagnostics for Viral Encephalitis/Meningitis Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-Of-Care Setting Alan Wu, PhD Department of Laboratory Medicine
Multiplexed Viral and Cytokine Response Assays Using NanoString Technology Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Clinitek Novus Second Clinical Trial Protocol Alan Wu, PhD Department of Laboratory Medicine
Pathogen Discovery in PREDICT Human and Wildlife samples to Detect and Identify Viruses Present, Both Known and Novel Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Preliminary evaluation of ReLIA Point-of-Care Analyzer for Cardiac Troponin Alan Wu, PhD Department of Laboratory Medicine
AID-Mediated Genetic Instability in Bcr-Abl1-Transformed B Cell Lineage Leukemia Markus Muschen, MD, PhD Department of Laboratory Medicine
Clin 0004 Characterization of Viral Hemorrhagic Fevers of Unknown Origin Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Clin 0003 Identification and Characterization of a Putative Novel Poxvirus in the DRC Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Deep Sequencing Clinical Analysis Tool for Infectious Disease Steve Miller, MD, PhD Department of Laboratory Medicine
Genome-Wide Association Study to Examine Genes Associated with An Increased Risk of Febrile Seizure in Children Following Measles-Containing Vaccines Mark Seielstad, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
12-10542, Genetic Disease Laboratory and Genetic Disease Screening Program on Clinical Laboratory Improvement Amendments (CLIA) Alan Wu, PhD Department of Laboratory Medicine
CCD Study- RNA Sequencing Charles Chiu, MD, PhD Department of Laboratory Medicine
Identifying Variants Casual for Type 2 Diabetes in Major Human Populations Mark Seielstad, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Pathogen characterization and discovery by deep sequencing of two major vectors associated with Lyme disease and other tickborne infections Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Establishing a Core Facility for Virus Detection and Discovery Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Comprehensive Diagnostics for Viral Encephalitis/Meningitis Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Genetics of Brazilian Populations Mark Seielstad, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting Alan Wu, PhD Department of Laboratory Medicine
Broad Detection of Infectious Agents in Blood by Microarrays and Deep Sequencing Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Processing Uganda Swabs for Trachoma Alternative Indicators Study Julius Schachter, PhD Department of Laboratory Medicine, Francis I. Proctor Foundation for Research in Ophthalmology
Infectious Origins of Childhood Leukemia [II] Markus Muschen, MD, PhD Department of Laboratory Medicine
Health Outcomes in Blood Donors and Recipients Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine
Detection of C. trachomatis on eye swabs Julius Schachter, PhD Department of Laboratory Medicine
Whole Blood/Serum Samples from Patients with Hepatitis Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Negative Feedback and oncogene signaling in leukemia Markus Muschen, MD, PhD Department of Laboratory Medicine
Genetic Disease Laboratory and Genetic Disease Screening Program on Clinical Laboratory Improvement Amendments (CLIA) 15-10151 Alan Wu, PhD Department of Laboratory Medicine
Real-Time Detection of Bloodborne Pathogens by Unbiased Nanopore Sequencing 20150506 Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Serological prevalence of viral hemorrhagic fevers in Equatorial Africa Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Pharmacological hyperactivation of Ras-MAPK signaling to target Ph+ ALL Markus Muschen, MD, PhD Department of Laboratory Medicine
Metabiota - Viral Surveillance for the PREDICT Program 20150410 Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Intraosseous Sampling for Postmortem Drugs and Alcohol Testing From a Medical Examiner's Office Alan Wu, PhD Department of Laboratory Medicine
Signaling by Cytoplasmic Tyrosine Kinases in Leukocytes Clifford Lowell, MD, PhD Department of Laboratory Medicine
Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - Central Laboratory Mark Seielstad, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - Domestic Sites - PHASE 2 Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine
A point of care assay for chlamydia to assure prompt treatment in at risk minorities Julius Schachter, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine, Francis I. Proctor Foundation for Research in Ophthalmology
Identification of Signaling Pathways Associated with Lyme Disease Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
TO#2 Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) - International Sites Edward Murphy, MD, MPH IGHS Faculty Affiliate, Department of Laboratory Medicine
Variation In Immune Response Of The Endangered Horseshoe Crab, Limulus Polyphemus: A Tool For Biomonitoring The Health Of Coastal Lagoons In The Yucatan Peninsula, Mexico Jack Levin, MD Department of Laboratory Medicine
Pathogen discovery and epidemiology in tick vectors associated with Lyme-like diseases Charles Chiu, MD, PhD IGHS Faculty Affiliate, Department of Laboratory Medicine
Mechanisms of Neutrophil Activation Clifford Lowell, MD, PhD Department of Laboratory Medicine
Targeting BCL6 in tyrosine kinase-driven leukemia Markus Muschen, MD, PhD Department of Laboratory Medicine
Mechanisms of Neutrophil Activation Clifford Lowell, MD, PhD Department of Laboratory Medicine
Negative feedback signaling in tyrosine kinase-driven leukemia Markus Muschen, MD, PhD Department of Laboratory Medicine