NIH National Institute of General Medical Sciences

53 Archived Projects

Title Investigator Start
End
Structural Biology and Targeted Drug Design for AIDS Ortiz De Montellano
Selective Destruction of Cytochrome P450 by Drugs Ortiz De Montellano
Biochemistry and Hepatic Toxicity of Carbon Radicals Ortiz De Montellano
Clinical Pharmacology, Drug Action and Pharmacogenetics Benowitz
Mechanism, Specificity, and Inhibition of Cytocchrome P450 Ortiz De Montellano
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach Krogan
Global Genetic Interaction Profiling in Prokaryotes
A Web-Based Automatic Virtual Screening System Shoichet
TGFBM2 In Development and Disease
Structure, Function and Inhibition of Beta-Lactamases Shoichet
Clinical Pharmacology, Drug Action and Pharmacogenetics Burchard
Pharmacogenomics of Membrane Transporters
Mutational Analysis of E. Coli Core RNA Polymerase
UCSF/UCB Joint Graduate Group in Bioengineering Desai
Medical Scientist Training Program
Mechanism, Specificity, and Inhibition of Cytochrome P450 Ortiz De Montellano
Modeling Contact Investigation and Rapid Response Porco
Integrating computation and genetics to quantify specificity in protein networks Krogan
Microtubule Complexes Involved in Intracellular Transport Vale
Characterizing Natural Product Permeability and Bioactivity Lexa
A Toolkit for Light-Control of Molecular Processes in Living Cells
A Specific Mechanism for Non-Specific Inhibition Shoichet
Function and Pathway Analysis Using Systems-Level Approaches in Prokaryotes
Cell Cycle Regulation by Ubiquitin Ligases
HARC Center: HIV Accessory and Regulatory Complexes Frankel
Regulation and Targets of the DNA Damage Checkpoint
Regulation of the Heat Shock Response in E. coli
Signal Integration in Neutrophil Chemotaxis (2 R01 GM084040-06)
A Specific Mechanism for Non-Specific Inhibition Shoichet
Antigen Decoding by T cells
A Web-Based Automatic Virtual Screening System Shoichet
A Pharmacogenomics Study of HIV Latency: The Role of Anti-Programmed Cell Death-1 (PD-1) Signaling Lee
Physical and Genetic Interaction Landscape of the Tyrosine Kinome Krogan
Design and Experimental Testing of New Docking Methods Shoichet
Research Training in Chemistry and Chemical Biology Craik
Testosterone's role in sex-specific outcomes after early anesthesia Sall
Structure and mechanism of the dyein motor Vale
Enabling New Translational Discoveries Using a Genomic Data-Driven Nosology Butte
Transition zone control of ciliary signaling Reiter
Research Training in Chemistry and Chemical Biology Craik
Clinical Pharmacology, Drug Action and Pharmacogenetics Burchard
Hepatic degradation of cytochrome P450 enzymes Correia
Allosteric Inhibition of a Family of Proteolytic Enzymes Craik
Optogenetic dissection of the growth and activation network in T cells O'donoghue
Research Training in Chemistry and Chemical Biology Craik
Creating an online resource center for training and professional development in the biomedical sciences Vale
Systematic Phenotypic Analysis of the Gram-positive Envelope Peters
Regulation of Microtubule-Based Motility Vale
A Web-Based Automatic Virtual Screening System Shoichet
A Specific Mechanism for non-specific inhibition Shoichet
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism Shoichet
Research Training in Chemistry and Chemical Biology Craik
Ebola modeling: behavior, asymptomatic infection, and contacts Porco