NIH National Institute of General Medical Sciences

53 Archived Projects

Title Investigator Start End
Structural Biology and Targeted Drug Design for AIDS Ortiz De Montellano
Selective Destruction of Cytochrome P450 by Drugs Ortiz De Montellano
Biochemistry and Hepatic Toxicity of Carbon Radicals Ortiz De Montellano
Clinical Pharmacology, Drug Action and Pharmacogenetics Benowitz
Mechanism, Specificity, and Inhibition of Cytocchrome P450 Ortiz De Montellano
Global Genetic Interaction Profiling in Prokaryotes
A Specific Mechanism for Non-Specific Inhibition Shoichet
A Web-Based Automatic Virtual Screening System Shoichet
TGFBM2 In Development and Disease
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach Krogan
Characterizing Natural Product Permeability and Bioactivity Lexa
Structure, Function and Inhibition of Beta-Lactamases Shoichet
Clinical Pharmacology, Drug Action and Pharmacogenetics Burchard
Mutational Analysis of E. Coli Core RNA Polymerase
A Toolkit for Light-Control of Molecular Processes in Living Cells
Integrating computation and genetics to quantify specificity in protein networks Krogan
Function and Pathway Analysis Using Systems-Level Approaches in Prokaryotes
Pharmacogenomics of Membrane Transporters
UCSF/UCB Joint Graduate Group in Bioengineering Desai
Medical Scientist Training Program
Mechanism, Specificity, and Inhibition of Cytochrome P450 Ortiz De Montellano
Creating an online resource center for training and professional development in the biomedical sciences Vale
Systematic Phenotypic Analysis of the Gram-positive Envelope Peters
A Specific Mechanism for Non-Specific Inhibition Shoichet
Regulation of the Heat Shock Response in E. coli
Research Training in Chemistry and Chemical Biology Craik
Enabling New Translational Discoveries Using a Genomic Data-Driven Nosology Butte
Cell Cycle Regulation by Ubiquitin Ligases
A Web-Based Automatic Virtual Screening System Shoichet
Signal Integration in Neutrophil Chemotaxis (2 R01 GM084040-06)
HARC Center: HIV Accessory and Regulatory Complexes Frankel
Regulation and Targets of the DNA Damage Checkpoint
Microtubule Complexes Involved in Intracellular Transport Vale
Optogenetic dissection of the growth and activation network in T cells O'donoghue
Antigen Decoding by T cells
Research Training in Chemistry and Chemical Biology Craik
Modeling Contact Investigation and Rapid Response Porco
Allosteric Inhibition of a Family of Proteolytic Enzymes Craik
Research Training in Chemistry and Chemical Biology Craik
Design and Experimental Testing of New Docking Methods Shoichet
Structure and mechanism of the dyein motor Vale
Transition zone control of ciliary signaling Reiter
Physical and Genetic Interaction Landscape of the Tyrosine Kinome Krogan
A Pharmacogenomics Study of HIV Latency: The Role of Anti-Programmed Cell Death-1 (PD-1) Signaling Lee
Testosterone's role in sex-specific outcomes after early anesthesia Sall
A Web-Based Automatic Virtual Screening System Shoichet
Hepatic degradation of cytochrome P450 enzymes Correia
A Specific Mechanism for non-specific inhibition Shoichet
Clinical Pharmacology, Drug Action and Pharmacogenetics Burchard
Regulation of Microtubule-Based Motility Vale
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism Shoichet
Research Training in Chemistry and Chemical Biology Craik
Ebola modeling: behavior, asymptomatic infection, and contacts Porco