NIH National Institute of General Medical Sciences

Archived Projects

53 Archived Projects

Title	Investigator	Start	End
Structural Biology and Targeted Drug Design for AIDS	Ortiz De Montellano	9/1/02	8/31/07
Selective Destruction of Cytochrome P450 by Drugs	Ortiz De Montellano	7/1/03	9/29/07
Biochemistry and Hepatic Toxicity of Carbon Radicals	Ortiz De Montellano	7/1/04	6/30/09
Clinical Pharmacology, Drug Action and Pharmacogenetics	Benowitz	7/1/05	6/30/10
Mechanism, Specificity, and Inhibition of Cytocchrome P450	Ortiz De Montellano	9/30/07	6/30/11
Global Genetic Interaction Profiling in Prokaryotes		9/25/08	7/31/12
A Specific Mechanism for Non-Specific Inhibition	Shoichet	4/1/12	2/28/13
A Web-Based Automatic Virtual Screening System	Shoichet	4/1/09	5/31/13
TGFBM2 In Development and Disease		4/10/09	3/31/14
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach	Krogan	1/3/08	4/30/14
Characterizing Natural Product Permeability and Bioactivity	Lexa	2/1/12	1/31/15
Structure, Function and Inhibition of Beta-Lactamases	Shoichet	4/1/10	2/28/15
Clinical Pharmacology, Drug Action and Pharmacogenetics	Burchard	7/1/10	6/30/15
Mutational Analysis of E. Coli Core RNA Polymerase		8/1/10	7/31/15
A Toolkit for Light-Control of Molecular Processes in Living Cells		3/1/12	1/31/16
Integrating computation and genetics to quantify specificity in protein networks	Krogan	8/1/11	5/31/16
Function and Pathway Analysis Using Systems-Level Approaches in Prokaryotes		7/1/12	6/30/16
Pharmacogenomics of Membrane Transporters		7/15/10	6/30/16
UCSF/UCB Joint Graduate Group in Bioengineering	Desai	7/1/11	6/30/16
Medical Scientist Training Program		7/1/11	6/30/16
Mechanism, Specificity, and Inhibition of Cytochrome P450	Ortiz De Montellano	7/1/11	6/30/16
Creating an online resource center for training and professional development in the biomedical sciences	Vale	10/9/15	10/10/16
Systematic Phenotypic Analysis of the Gram-positive Envelope	Peters	12/1/15	11/30/16
Regulation of the Heat Shock Response in E. coli		2/1/13	1/31/17
Research Training in Chemistry and Chemical Biology	Craik	2/1/15	1/31/17
A Specific Mechanism for Non-Specific Inhibition	Shoichet	6/1/14	1/31/17
Enabling New Translational Discoveries Using a Genomic Data-Driven Nosology	Butte	4/1/15	3/31/17
Cell Cycle Regulation by Ubiquitin Ligases		7/13/12	4/30/17
Signal Integration in Neutrophil Chemotaxis (2 R01 GM084040-06)		7/1/13	5/31/17
A Web-Based Automatic Virtual Screening System	Shoichet	7/1/14	5/31/17
Optogenetic dissection of the growth and activation network in T cells	O'donoghue	9/1/15	8/31/17
HARC Center: HIV Accessory and Regulatory Complexes	Frankel	9/1/12	8/31/17
Regulation and Targets of the DNA Damage Checkpoint		9/1/12	8/31/17
Microtubule Complexes Involved in Intracellular Transport	Vale	9/1/11	8/31/17
Antigen Decoding by T cells		6/5/14	2/28/18
Research Training in Chemistry and Chemical Biology	Craik	6/25/15	5/31/18
Modeling Contact Investigation and Rapid Response	Porco	8/1/11	6/30/18
Allosteric Inhibition of a Family of Proteolytic Enzymes	Craik	8/6/15	7/31/18
Research Training in Chemistry and Chemical Biology	Craik	9/25/15	9/24/18
Design and Experimental Testing of New Docking Methods	Shoichet	12/1/14	11/30/18
Structure and mechanism of the dyein motor	Vale	4/1/15	3/31/19
Transition zone control of ciliary signaling	Reiter	5/1/15	4/30/19
Physical and Genetic Interaction Landscape of the Tyrosine Kinome	Krogan	9/1/14	6/30/19
A Pharmacogenomics Study of HIV Latency: The Role of Anti-Programmed Cell Death-1 (PD-1) Signaling	Lee	8/5/14	7/31/19
Testosterone's role in sex-specific outcomes after early anesthesia	Sall	3/1/15	2/29/20
A Web-Based Automatic Virtual Screening System	Shoichet	8/1/16	4/30/20
Hepatic degradation of cytochrome P450 enzymes	Correia	7/1/15	5/31/20
A Specific Mechanism for non-specific inhibition	Shoichet	9/1/16	5/31/20
Clinical Pharmacology, Drug Action and Pharmacogenetics	Burchard	7/1/15	6/30/20
Regulation of Microtubule-Based Motility	Vale	7/1/16	6/30/21
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism	Shoichet	6/1/17	5/31/22
Research Training in Chemistry and Chemical Biology	Craik	7/1/17	6/30/22
Ebola modeling: behavior, asymptomatic infection, and contacts	Porco	9/1/19	8/31/23

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NIH National Institute of General Medical Sciences

53 Archived Projects