Creating Polyketide Antibiotic Diversity by Engineering Cytochrome P450 Enzymes / UC Discovery |
|
Immunology |
|
|
UCSF Comprehensive Center for Immunologic Diseases (CCID) |
Jeffrey Bluestone, PhD |
Immunology |
|
|
Use of r-hGh to Enhance Thymopoiesis and to Facilitate Immune Restoration in Individuals Infected with HIV-1 |
Mike McCune, MD, PhD |
HIV/AIDS, Immunology |
|
|
Effects of Viral Escape on Memory T-Cell Muturation |
Eric Delwart, PhD |
Immunology |
|
|
Phase II Double Blinded, Placebo-Controlled, Efficacy and Safety Evaluation of Allergen Immunotherapy Co-Administered with Omalizumab, an Anti-IgE mAb |
Jeffrey Bluestone, PhD |
Immunology |
|
|
Regulation of Human Thymic Function in Vivo |
Mike McCune, MD, PhD |
Immunology |
|
|
Systematic Review Series on "Antibody and Antigen Detection for the Immunodiagnosis of Tuberculosis" |
Philip Hopewell, MD |
Tuberculosis, Immunology, Systematic Reviews and Guideline Development |
|
|
T Regulatory Cells and T Cell Activation in HIV Disease |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
HIV Controllers: A Potential Model for HIV Eradication |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
HIV Vaccine Trials Network - Laboratory Personnel Support |
|
Immunology |
|
|
Valganciclovir to Reduce T Cell Activation in HIV Infection |
Peter Hunt, MD |
HIV/AIDS, Drug and Diagnostics Development, Immunology |
|
|
Elite Controllers |
Steven Deeks, MD |
HIV/AIDS, Immunology, Genetics |
|
|
CORE B: Intracellular Pathogens and Innate Immunity |
Joseph Derisi, PhD |
Tuberculosis, Immunology |
|
|
Project 2: Effect of Humanized Anti Pcrv Antibody on Total Bacterial Community Composition of Adult Patients with Ventilator-Associated Pneumonia |
|
Immunology |
|
|
Chemoprophylaxis and HIV-Host Interactions [II] |
|
HIV/AIDS, Immunology |
|
|
Immunogenetic Studies of Autoimmune Disease |
|
Immunology |
|
|
Immunological Targeting of APOBEC Proteins to Cure HIV Infection |
|
HIV/AIDS, Immunology |
|
|
Raltegravir Intensification in Antiretroviral-Treated Patients Exhibiting a Suboptimal CD4+T Cell Response |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
Innate Effector Function and HIV-1 Control |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
Testing novel adjuvants to enhance mucosal immunity elicited by inactivated poliovirus vaccine (IPV) |
Raul Andino-Pavlovsky, PhD |
Drug and Diagnostics Development, Immunology |
|
|
Core B: Intracellular Pathogens and Innate Immunity |
Joseph Derisi, PhD |
Zoonosis, Emerging Disease, and Drug Resistance, Immunology |
|
|
Inflammatory and Clinical Consequences of Low-Level Viremia in HIV-1 Infected Patients |
|
HIV/AIDS, Immunology |
|
|
HIV Entry Inhibitors: A New Therapeutic Option |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
UCSF/Ragon Collaboration on HIV "Elite" Controllers |
Steven Deeks, MD |
HIV/AIDS, Drug and Diagnostics Development, Immunology, Genetics |
|
|
CNS Immune / Inflammatory Biomarkers in HIV Controllers |
Richard Price, MD |
HIV/AIDS, Immunology |
|
|
Treating HIV-Infected Elite Controllers as a Model of HIV Remission |
|
HIV/AIDS, Immunology |
|
|
Identification of the CD8+ Cell Anti-HIV Factor (CAF) |
|
HIV/AIDS, Immunology |
|
|
Characterizing the Role of Immune Activation in HIV Persistence |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
HLA-A Low Resolution Typing |
|
Surgery and Anesthesia, Immunology |
|
|
Initiation of Allergic Immunity by Parasites |
Richard Locksley, MD |
Immunology |
|
|
Development of Human mAbs to Target Cardiomyocytes and Cardiac Fibroblasts |
|
Cardiovascular Disease, Immunology |
|
|
Childhood Arthritis and Rheumatology Research Alliance Registry (CARRA Registry): Lupus Nephritis Consensus Treatment Plan Maintenance Phase |
|
Immunology |
|
|
Effects of CCR5 - delta-32 Heterozygosity on the HIV-1 Reservoir |
Steven Deeks, MD |
HIV/AIDS, Immunology, Genetics |
|
|
DNA methylation profiling in Rheumatoid Arthritis |
|
Immunology |
|
|
Global Innate Immune Responses to HIV-1 Infection |
Nevan Krogan, PhD, MSc |
HIV/AIDS, Immunology |
|
|
Development of Regulatory T-Cells for Treatment of Autoimmune Disease |
Jeffrey Bluestone, PhD |
Immunology, Pharmacology and Drug Treatment |
|
|
Health Professional Research Preceptorship |
|
Immunology |
|
|
Stem Cell differentiation to thymic epithelium for inducing immune tolerance to stem cells |
|
Immunology |
|
|
Development of Human mABs to CXCR1 and CXCR2 |
|
Immunology |
|
|
Recent Thymic Emigrants of the CD4 T-Cell Lineage |
Mike McCune, MD, PhD |
Immunology |
|
|
A 6 month Multi-center, Open-label Safety Study of VIMOVO in Adolescents |
|
Immunology, Adolescent Health |
|
|
Genome-Wide Association Study to Examine Genes Associated with An Increased Risk of Febrile Seizure in Children Following Measles-Containing Vaccines |
Mark Seielstad, PhD |
Infectious Disease, Transfusion Medicine, Immunology, Pharmacology and Drug Treatment, Pediatrics, Epidemiology and Surveillance |
|
|
Mechanisms of B Cell Responses in Autoimmune Disease: C12-ALE05-CSF |
|
Immunology |
|
|
Collaborative Network for Clinical Research on Immune Tolerance - Offcampus Portion |
Jeffrey Bluestone, PhD |
Diabetes, Immunology |
|
|
Collaborative Network for Clinical Research on Immune Tolerance |
Jeffrey Bluestone, PhD |
Diabetes, Immunology |
|
|
Gender-specific Differences Affecting Reactivation of Latent HIV in Treated Patients |
Steven Deeks, MD |
HIV/AIDS, Immunology, Women's Health |
|
|
A Novel Myeloid Subset Mediating Tolerance to Malaria |
|
Malaria, Immunology |
|
|
Identifying and targeting HIV persistence in T Cell subsets during ART |
Steven Deeks, MD |
Drug and Diagnostics Development, Immunology, Genetics |
|
|
Health Professional Research Preceptorship |
|
Immunology, Residencies, Fellowships, and Postdoctoral Training |
|
|
Health Professional Research Preceptorship |
|
Immunology, Residencies, Fellowships, and Postdoctoral Training |
|
|
Genetic Diversity as a Determinant of Viral Adaptation and Pathogenesis |
Raul Andino-Pavlovsky, PhD |
Infectious Disease, Immunology |
|
|
Interferon-independent mechanisms of malaria restriction by helper T cells |
Mike McCune, MD, PhD |
HIV/AIDS, Malaria, Immunology |
|
|
Medical and Graduate Student Preceptorship - Mok |
|
Immunology, Residencies, Fellowships, and Postdoctoral Training |
|
|
Exploring the role of a novel, polymorphic protein family in M. tuberculosis pathogenesis |
|
Tuberculosis, Immunology |
|
|
Trefoil Factors Regulate Th2 Immunity |
|
Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Immunology |
|
|
Reactivation of latent HIV using recombinant galectin-9 |
|
HIV/AIDS, Immunology |
|
|
Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophages |
|
Tuberculosis, Immunology |
|
|
Treatment of SLE with ajulemic acid,a non-psychoactive cannabinoid derivative |
|
Immunology |
|
|
The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation |
Jeffrey Bluestone, PhD |
Immunology |
|
|
Immunomodulation of transplant rejection by anti-CD3 mAb |
Jeffrey Bluestone, PhD |
Immunology |
|
|
Quantitative mapping of interactions between dengue virus and its hosts |
|
Zoonosis, Emerging Disease, and Drug Resistance, Immunology |
|
|
A Specific Mechanism for Non-Specific Inhibition |
|
Immunology |
|
|
Enabling New Translational Discoveries Using a Genomic Data-Driven Nosology |
Atul Butte, MD, PhD |
Cancer/Oncology, Immunology |
|
|
HIV-Specific T-Cell Responses in Rectal Mucosa |
Elizabeth Sinclair, PhD |
HIV/AIDS, Immunology |
|
|
Plasmodium Falciparum Infection and Interference with Effective B Cell Memory |
Bryan Greenhouse, MD |
Malaria, Immunology, Pediatrics |
|
|
NP25737 A Phase I Pharmacokinetic and Safety Study of Tocilizumab (TCZ) in Patients Less Than 2 Years Old With Active Systemic Juvenile Idiopathic Arthritis |
|
Noncommunicable and/or Chronic Disease, Immunology, Pediatrics |
|
|
Defining critical events in early HIV infection-effects of alcohol and early ART |
Mike McCune, MD, PhD |
HIV/AIDS, Immunology, Substance Abuse |
|
|
University of California Global Health Institute Program for Fellows and Scholars |
Craig Cohen, MD, MPH |
Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Effectiveness, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, Policy and Standards of Care, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training |
|
|
A pilot study of DNA methylation and response to treatment in RA |
|
Immunology |
|
|
UCSF-GIVI Center for AIDS Research (CFAR) |
Paul Volberding, MD |
HIV/AIDS, Tuberculosis, Malaria, Cancer/Oncology, Cardiovascular Disease, Drug and Diagnostics Development, Immunology, Pharmacology and Drug Treatment, Neurology and Mental Health, Trauma and PTSD, Women's Health, Pediatrics, Implementation and Behavioral Science, Training and Capacity Building, Training International Scholars and Clinicians |
|
|
Oxygen Sensors and P450 Monooxygenases in Mycobacertium tuberculosis |
|
Tuberculosis, Immunology |
|
|
Optogenetic dissection of the growth and activation network in T cells |
|
Immunology |
|
|
HARC Center: HIV Accessory and Regulatory Complexes |
Alan Frankel, PhD |
Zoonosis, Emerging Disease, and Drug Resistance, HIV/AIDS, Immunology |
|
|
Placental Malaria: The Role of Macrophages in Placental Inflammation - RSDP Valderramos |
Stephanie Valderramos, MD, PhD |
Malaria, Immunology |
|
|
Placental Malaria: The Role of Macrophages in Placental Inflammation - RSDP Valderramos Burroughs Wellcome Fund |
Stephanie Valderramos, MD, PhD |
Malaria, Immunology |
|
|
Mother-child genetic contributions to autoimmunity |
|
Immunology |
|
|
Improve the Cho Expression of a ScFv Fragment by Optimizing the DNA Sequence of the ingle chain variable fragment ScFv and/or Leader Sequence |
|
Drug and Diagnostics Development, Immunology |
|
|
Antigen Decoding by T cells |
|
Immunology |
|
|
Vertical Transmission of Zika Virus: Histopathological Investigations at the Maternal- Fetal Interface |
Stephanie Valderramos, MD, PhD |
Infectious Disease, Drug and Diagnostics Development, Immunology |
|
|
Mechanisms of Neutrophil Activation |
|
Immunology |
|
|
HIV cure with CCR5 negative human IPS hematopoietic stem cells |
|
HIV/AIDS, Drug and Diagnostics Development, Immunology |
|
|
Gilead Sciences Research Scholars Program in Cystic Fibrosis. |
Oren Rosenberg, MD, PhD |
Immunology |
|
|
Initiation of allergic immunity by parasites |
Richard Locksley, MD |
Immunology |
|
|
HINT: HIV Immune Networks Team Modeling Core |
Nevan Krogan, PhD, MSc |
HIV/AIDS, Immunology |
|
|
ACTG A5335s Specialty Lab |
Diane Havlir, MD |
Drug and Diagnostics Development, Immunology, Genetics |
|
|
Pets and the Infant Microbiome: Effect on Immune Maturation and Atopic Asthma |
|
Occupational and Environmental Disease, Immunology |
|
|
Enhancing Control of HIV by Inhibiting TRAIL |
Steven Deeks, MD |
HIV/AIDS, Drug and Diagnostics Development, Immunology |
|
|
BSL3 upgrading for Live-attenuated poliovirus testing |
Raul Andino-Pavlovsky, PhD |
Infectious Disease, Immunology |
|
|
Allosteric Inhibition of a Family of Proteolytic Enzymes |
Charles Craik, PhD |
Immunology, Pharmacology and Drug Treatment |
|
|
Proteomics Analysis of Host-Pathogen Interactions in Histoplasma |
Anita Sil, MD, PhD |
Opportunistic Infection, Immunology |
|
|
Antigen Specificity of Regulatory T cells in Type 1 diabetes T1D |
Jeffrey Bluestone, PhD |
Diabetes, Immunology |
|
|
Impact of interferon-alpha inhibition on immune function and viral persistence in HIV disease |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
New ways of treating pancreatic cancer based on reversing K-Ras-mediated stemness |
|
Cancer/Oncology, Immunology |
|
|
VEGF signaling in placental development and disease |
Susan Fisher, PhD |
Immunology, Labor and Delivery |
|
|
Host-Directed Strategies to Create Synergistic Antibacterial Therapies |
|
Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development, Immunology |
|
|
HIV-Specific T-Cell Responses in Rectal Mucosa |
Peter Hunt, MD |
Immunology |
|
|
Trefoil Factor Proteins Modulate Host Immunity against Hookworms |
|
Zoonosis, Emerging Disease, and Drug Resistance, Immunology |
|
|
Physical and Genetic Interaction Landscape of the Tyrosine Kinome |
Nevan Krogan, PhD, MSc |
Cancer/Oncology, Diabetes, Immunology |
|
|
Microbial Pathogenesis and Host Defense |
Joanne Engel, MD, PhD |
Immunology, Residencies, Fellowships, and Postdoctoral Training |
|
|
A Pharmacogenomics Study of HIV Latency: The Role of Anti-Programmed Cell Death-1 (PD-1) Signaling |
Sulggi Lee, MD |
HIV/AIDS, Immunology |
|
|
Alcohol's impact on immunological and virological profiles in HIV patients |
Mandana Khalili, MD |
HIV/AIDS, Immunology, Substance Abuse |
|
|
Integrative Program in Complex Biological System (ipCBS) |
Joseph Derisi, PhD |
Drug and Diagnostics Development, Immunology, Genetics, Residencies, Fellowships, and Postdoctoral Training |
|
|
Generation of therapeutic antibodies for serotype F botulism (Continuation of A120963 from NIH G Pool to Subaccount) |
|
Immunology |
|
|
Impact of Cannabis on Inflammation and Viral Persistence in Treated HIV/SIV |
Peter Hunt, MD |
HIV/AIDS, Immunology |
|
|
Immunologic determinants of age-related macular degeneration |
Peter Hunt, MD |
Eye Disease and Blindness, Immunology, Aging |
|
|
Programming Long Term Durable HIV-1 Specific T cell Responses |
Steven Deeks, MD |
HIV/AIDS, Immunology |
|
|
Identification of Cobra-specific antibodies |
Charles Craik, PhD |
Zoonosis, Emerging Disease, and Drug Resistance, Immunology |
|
|
The impact of TB co-infection on the reservoir of persistent HIV in vivo |
Mike McCune, MD, PhD |
HIV/AIDS, Tuberculosis, Immunology |
|
|
Naturally acquired immunity to norovirus in a newborn cohort in Peru |
Caryn Bern, MD, MPH |
Infectious Disease, Immunology, Newborn and Infant Health |
|
|
Transfusion science and HIV, HTLV, and dengue research in Brazil |
Philip Norris, MD |
Infectious Disease, HIV/AIDS, Immunology, Health Systems Strengthening, Risk Reduction and Prevention, Training and Capacity Building |
|
|
Immunology & epidemiology of intestinal infectious diseases |
Robert Owen, MD |
Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Epidemiology and Surveillance |
|
|
Zika virus infection using models of the human placenta |
Lenore Pereira, PhD |
Immunology, Newborn and Infant Health |
|
|
Biomedical simulation models describing how molecular level events effect changes in phenotype |
C. Anthony Hunt, PhD |
Immunology, Genetics |
|
|
Developing new vaccines for Global Health applications |
|
Drug and Diagnostics Development, Immunology |
|
|
IgA regulation of mucosal biome |
Keith Mostov, MD, PhD |
Immunology |
|
|
Antigen export in M. tuberculosis evasion of CD4 T cells |
Joel D. Ernst, MD |
Tuberculosis, Immunology |
|
|
Dissecting the effect of paracrine responses to Zika virus on neurodevelopment in the human brain |
Hanna Retallack, AB |
Zoonosis, Emerging Disease, and Drug Resistance, Immunology |
|
|
Single Cell Characterization of Latent HIV-1 Reservoirs |
|
HIV/AIDS, Immunology |
|
|
Role of Antigen-Specific T Cell Responses in the Control of TB |
Joel D. Ernst, MD |
Tuberculosis, Immunology |
|
|
Novel Linkers for Antibody-Drug Conjugates |
Adam Renslo, PhD |
Immunology |
|
|
Effect of IL-1B inhibition on inflammation and cardiovascular risk in HIV |
|
HIV/AIDS, Immunology |
|
|
Investigating Mechanisms of HIV Persistence in the Gut |
Peter Hunt, MD |
HIV/AIDS, Immunology |
|
|
Targeting latent HIV-1 Reservoirs with the Antibody-Drug Conjugate, Brentuximab Vedotin |
|
HIV/AIDS, Immunology |
|
|
Selective AAK1 and GAK inhibitors for combating Dengue and other emerging viral infections |
Raul Andino-Pavlovsky, PhD |
Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Immunology |
|
|
Host-pathogen interactions: Unveiling common mechanisms for rewiring host factors in infectious processes |
Nevan Krogan, PhD, MSc |
Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Genetics |
|
|
Cellular and Bacterial Dynamics in Tuberculosis |
Joel D. Ernst, MD |
Tuberculosis, Immunology |
|
|
Regulation of Innate Immune Signaling by Lyn Kinase |
|
Immunology |
|
|
Timing of ART and homeostasis of the persistent HIV reservoir in the adult |
Mike McCune, MD, PhD |
HIV/AIDS, Immunology |
|
|
Effector and regulatory T cell responses and protection from clinical malaria |
Margaret Feeney, MD |
Malaria, Drug and Diagnostics Development, Immunology |
|
|
HIV Cures - Paving the way towards elimination of HIV persistent CD4 T cell in vivo |
|
HIV/AIDS, Immunology |
|
|
Precision Targeting of Castration Resistant Prostate Cancer with a Novel Ferrous Iron-Dependent Therapeutic Delivery and Tumor Imaging Strategy |
Adam Renslo, PhD |
Cancer/Oncology, Immunology |
|
|
Long-term Effects of IDU, HIV, HCV and the Impact of HCV Cure on Immune Activation and Liver Fibrosis in Aging Women |
Phyllis Tien, MD |
Infectious Disease, HIV/AIDS, Immunology, Women's Health |
|
|
Role of Ceramide in Hepatic Stellate Cell Activation and Liver Fibrosis |
Jennifer Chen, MD |
Immunology |
|
|
HPMI: Host Pathogen Mapping Initiative |
Nevan Krogan, PhD, MSc |
Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Genetics |
|
|
747-303: A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of beticholic Acid in Subjects with Nonalcoholic Steatohepatitis |
Mandana Khalili, MD |
Immunology |
|
|
Clinical trials to improve the treatment of drug-sensitive and MDR-TB |
Patrick Phillips, PhD, MS, MA |
Tuberculosis, Immunology, Pharmacology and Drug Treatment |
|
|
Placental malaria: The role of inflammation at the maternal-fetal interface |
Stephanie Valderramos, MD, PhD |
Malaria, Immunology, Labor and Delivery, Newborn and Infant Health |
|
|
Adalimumab in Juvenile Idiopathic Arthritis-associated Uveitis Trial (ADJUST) |
Nisha Acharya, MD |
Eye Disease and Blindness, Immunology |
|
|
Host genetic predictors of plasma IL-1b levels and pharmacogenomics of in vivo IL-1b blockade during treated HIV disease |
Sulggi Lee, MD |
HIV/AIDS, Immunology, Genetics, Aging |
|
|