UCSF-Gladstone Center for AIDS Research (CFAR)

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Investigator: Paul Volberding, MD
Sponsor: NIH National Institute of Allergy and Infectious Disease

Location(s): Kenya; Uganda; Tanzania; Zimbabwe; South Africa; Peru

Description

The UCSF-Gladstone Center for AIDS Research (CFAR) seeks to expand HIV research occurring at the intersections of basic, clinical, and behavioral/ epidemiological scientific disciplines. Our Center's central goal is facilitating scientific progress in HIV by providing the broadest community of member investigators across our distributed research environment with direct and indirect resources such as access to emerging technologies and the availability of dynamic scientific cores.

To learn more, see the UCSF-Gladstone CFAR Program description.

Archived Sub Projects: 57

Sub Project Investigator Topics Location Start date End date
Subtype and CCR5/CXCR4 Tropism in HIV-1 Infected Ugandan Children Theodore Ruel, MD HIV/AIDS, Immunology Uganda
Immunodiagnosis of Active Tuberculosis in HIV Co-infected Patients: Local versus Peripheral T-cell Interferon Gamma Responses Adithya Cattamanchi, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development Uganda
Alcohol Use and HIV Treatment Failure in Mbarara, Uganda Judith Hahn, PhD, MD HIV/AIDS, Substance Abuse Uganda
Cognitive Impairment in HIV Over 60 Years of Age Victor Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment United States
Kisumu Street Children: A Pilot Study of STIs and HIV in Social Context HIV/AIDS, Pediatrics, Epidemiology and Surveillance Kenya
The Impact of Household Ventilation on Transmission of Tuberculosis Among Household Contacts of Active Tuberculosis Patients in Kampala, Uganda Gabriel Chamie, MD HIV/AIDS, Tuberculosis, Implementation and Behavioral Science, Risk Reduction and Prevention Uganda
The Role of Undiagnosed Opportunistic Infections in Early Mortality among HIV infected Patients Starting Antiretroviral Therapy in Africa HIV/AIDS, Opportunistic Infection, Engagement in Care Uganda
Determining the Feasibility and Accuracy of a Novel Biomarker for Cervical Dysplasia Among HIV-Infected Women in Western Kenya Megan Huchko, MD HIV/AIDS, Cancer/Oncology Kenya
HIV-1 Genital Shedding in Women Before and After Treatment for Cervical Dysplasia Megan Huchko, MD HIV/AIDS, Cancer/Oncology Kenya
Non-Commercial Culture Methods for Rapid Screening of Patients at Risk of Drug-Resistant Tuberculosis in Zimbabwe John Metcalfe, MD Tuberculosis, Drug and Diagnostics Development Zimbabwe
Sex Differences in Patterns of Migration and HIV Risk in Western Kenya Carol Camlin, PhD HIV/AIDS, Access or Barriers to Care, Immigration and Migration Kenya
The Clinical and Public Health Impact of Automated Nucleic Acid Testing for TB in San Francisco Tuberculosis, Epidemiology and Surveillance United States
Implementing a Sampling-based Approach to Measuring Patient Outcomes Among HIV-infected Patients Lost to Follow-up in East Africa: the I-SAMPOLE Study HIV/AIDS, Implementation and Behavioral Science, Engagement in Care, Treatment Adherence, Health Systems Strengthening Kenya
Building a Population-Based Cancer Registry in Dar es Salaam, Tanzania: A Pilot Project to Evaluate Completeness and Validity of Pathologic Data Katherine Van Loon Steitz, MD, MPH Cancer/Oncology Tanzania
Effect of Malaria Chemoprevention on Naturally Acquired T-Cell Mediated Immunity to Malaria Margaret Feeney, MD Malaria, Immunology Uganda
Examining Sexual Concurrency and Sexual Networks among Married Fishermen Couples in Kisumu District, Kenya Sexually Transmitted Infections (STIs), HIV/AIDS, Epidemiology and Surveillance Kenya
Family Planning Use Among Female Clients Attending The HIV/AIDS Clinic In Mbarara University Teaching Hospital HIV/AIDS, Women's Health, Family Planning, Newborn and Infant Health Uganda
Host Genetic Predictors of IDO-induced Tryptophan Catabolism Among HIV Infected Ugandans Maintaining Treatment-Mediated Viral Suppression Sulggi Lee, MD HIV/AIDS Uganda
Testing the Performance and Local Laboratory Capacity for p16INK4a ELISA for Cervical Cancer Screening Among HIV-Infected Women in Western Kenya Megan Huchko, MD HIV/AIDS, Drug and Diagnostics Development Kenya
Household HIV Testing During Tuberculosis Contact Investigation in Tanzania Elizabeth Fair, PhD, MPH Tuberculosis, Epidemiology and Surveillance, Engagement in Care Tanzania
It Takes a Village: Community Engagement in San Francisco and Kisumu to reduce HIV risk in Homeless Youth and Street Children Sexually Transmitted Infections (STIs), HIV/AIDS, Adolescent Health, Engagement in Care Kenya
Novel Computational Biology Methods for the Evaluation of Multi-Level/Combination Community HIV Prevention Interventions Edwin Charlebois, PhD HIV/AIDS, Epidemiology and Surveillance United States
Optimizing Nevirapine Dosing in Patients Co-infected with Tuberculosis and HIV in Harare, Zimbabwe HIV/AIDS, Tuberculosis, Pharmacology and Drug Treatment Zimbabwe
Provider Practices with Childhood Non-Malarial Fevers: A Pilot Study in Zanzibar Kimberly Baltzell, RN, PhD, MS Malaria, Pharmacology and Drug Treatment Tanzania
Acceptability and Feasibility of Providing Integrated HIV and Maternal and Child Health Services thorough Well Child Services in KwaZulu Natal, South Africa HIV/AIDS, Women's Health, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Access or Barriers to Care, Training and Capacity Building South Africa
Retention in HIV Care and Survival: Estimating Association and Causal Effect HIV/AIDS, Engagement in Care, Treatment Adherence United States
Mechanisms of CD4 T-Cell Death among HIV-Infected, HAART-Treated African Adults Displaying Poor CD4 T-Cell Reconstitution Despite Effective Viral Suppression HIV/AIDS, Immunology, Training and Capacity Building, Training International Scholars and Clinicians Uganda
Social Networking Technologies in Improving Treatment Engagement of Young Black HIV-positive Individuals Parya Saberi, PharmD HIV/AIDS, Treatment Adherence United States
Sputum M. Tuberculosis DNA Kinetics During TB Treatment in Patients with HIV Tuberculosis, Drug and Diagnostics Development Uganda
Evaluation of the Dynamics and Immuno-Virology of Human Papillomavirus Infections among Fishermen in Kisumu, Kenya Sexually Transmitted Infections (STIs), HIV/AIDS Kenya
Drug and Alcohol Abuses, Risky Sexual Behaviors, and HIV Risk among Sex Workers and Their Clients in Preah Sihanouk Province, Cambodia: A Pilot Study and Assessment of Prevention Opportunities HIV/AIDS, Epidemiology and Surveillance, Substance Abuse Cambodia
Development of a Combination HIV Prevention Intervention for Transgender Women in Peru HIV/AIDS, Women's Health, Access or Barriers to Care, Stigma and Discrimination, Implementation and Behavioral Science, Engagement in Care, Risk Reduction and Prevention, Training and Capacity Building, Training International Scholars and Clinicians Peru
Alcohol-Associated Unprotected Sexual Intercourse Among a Cohort of Newly Diagnosed HIV+ Adults in Mbarara, Uganda: A Pilot Study Sarah Woolf-King, PhD, MPH HIV/AIDS, Substance Abuse Uganda
Adaptation of a Male Partner Educational Intervention Tool for Vaginal Microbicide Trials Sexually Transmitted Infections (STIs), HIV/AIDS, Women's Health, Risk Reduction and Prevention, Training International Scholars and Clinicians Kenya
Reaching transgender women with home-based, self-HIV testing in San Francisco: a pilot acceptability and feasibility study Sheri Lippman, PhD, MPH HIV/AIDS, Engagement in Care, Risk Reduction and Prevention United States
Immunologic Biomarkers for Ruling-out Active Tuberculosis in HIV/AIDS Adithya Cattamanchi, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development Uganda
Cellular Determinants of Anti-rebound to Malaria in HIV-Exposed Children Discontinuing Chemoprophylaxis Uganda
Investigation of Pediatric HIV Disclosure in Kampala, Uganda HIV/AIDS, Neurology and Mental Health, Pediatrics Uganda
Mycobacterium Tuberculosis Acquisition in Early Childhood in Uganda Carina Marquez, MD Tuberculosis Uganda
A Cross-Sectional Study of Cerebral Vasoreactivity in HIV-infected Individuals Compared with Uninfected Controls Felicia Chow, MD United States
Promoting Positive Caregiver-Child Interaction between HIV-affected Children and their Caregivers with Depression in Kwa-Zulu Natal, South Africa HIV/AIDS, Neurology and Mental Health, Women's Health, Pediatrics South Africa
Aging, Cognitive Impairment and Ability to Engage in Healthcare Following Incarceration Mi-Suk Kang Dufour, PhD, MPH United States
Strategies to Obtain Systematic Samples and Measure HIV Prevalence in Migrant Women in Western Kenya Carol Camlin, PhD HIV/AIDS, Epidemiology and Surveillance, Implementation and Behavioral Science, Engagement in Care, Training and Capacity Building Kenya
Investigating How CD4 T Cells Die in HIV-1-Infected Patients: Potential Implications for a Novel Therapeutic Intervention HIV/AIDS, Immunology Uganda
Detection of HIV Transcription in Individual Cells by Flow Cytometry Elizabeth Sinclair, PhD HIV/AIDS, Immunology United States
Structure-Function Study of Semen-Derived HIV Enhancing Amyloids and Their Interactors HIV/AIDS United States
Cytokine Responses in Elite Controllers of HIV HIV/AIDS United States
Human Macrophage Heterogeneity in HIV-1 Infection HIV/AIDS, Immunology United States
Qualitative evaluation of a large "test and treat" trial: Characterizing baseline community contexts and implementation processes in SEARCH HIV/AIDS, Policy and Standards of Care, Implementation and Behavioral Science Kenya, Uganda
Impact of Neonatal Exposure to Malaria and HIV on the Frequency, Phenotype, and Function of __ T Cell Subsets at Birth HIV/AIDS, Malaria, Newborn and Infant Health Uganda
UCSF-GIVI CFAR: NIH/PEPFAR Collaboration for Implementation Sciences Adithya Cattamanchi, MD HIV/AIDS, Tuberculosis Uganda
Malaria parasitemia in HIV-infected and uninfected populations in Uganda Shereen Katrak, PhD, MPH HIV/AIDS, Malaria Uganda
Evaluation of a point-of-care assay for the diagnosis of Trichomonas vaginalis in women at high risk for HIV infection Sheila Nabweyambo, BSc, MS HIV/AIDS, Women's Health Uganda
Feasibility of Screening and Brief Intervention for Hazardous Alcohol use amongst HIV-infected Adults in Uganda: A Qualitative Study HIV/AIDS, Substance Abuse Uganda
Proof of concept of a self-administered digital health screener (SASH) to increase reporting of unhealthy alcohol use by persons with HIV in care in Uganda Judith Hahn, PhD, MD HIV/AIDS, Substance Abuse, Health Systems Strengthening Uganda
Immunologic and virologic response to a single dose of kansui herbal supplement in HIV-infected individuals maintaining antiretroviral therapy (ART)-mediated viral suppression Sulggi Lee, MD HIV/AIDS, Immunology China
Pathogenesis of HIV-associated chronic lung disease among vertically-infected children and adolescents John Metcalfe, MD HIV/AIDS, Chronic Respiratory Disease, Pediatrics, Newborn and Infant Health, Adolescent Health Zimbabwe