Testing Sponsor's Antiretroviral Enzyme Immunoassay Method

Investigator: Francesca Aweeka, PharmD
Sponsor: ARK Diagnostics, Incorporated

Location(s): United States


Protease inhibitors may not penetrate into the central nervous system in therapeutic concentrations, which may allow ongoing HIV replication and injury. The objective of this study was to determine atazanavir penetration into cerebrospinal fluid (CSF). Samples were assayed by rapid, automated enzyme immunoassays (ARK ATV-tests) provided by ARK Diagnostics.