Pediatric AIDS Clinical Trial Group (PACTG) Pharmacology Support Laboratories
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Investigator: Francesca Aweeka, PharmD
Sponsor: Social & Scientific Systems, Inc.
Location(s): United States
Description
A large clinical trials network that evaluates treatments for HIV-infected children and adolescents and that develops new therapeutic approaches for preventing mother-to-child transmission of HIV. Originally an independent network, Pediatric AIDS Clinical Trials Group (PACTG) investigators are now merged with the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group
A large clinical trials network that evaluates treatments for HIV-infected children and adolescents and that develops new therapeutic approaches for preventing mother-to-child transmission of HIV. Originally an independent network, Pediatric AIDS Clinical Trials Group (PACTG) investigators are now merged with the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group
In collaboration with the pharmaceutical industry, the PACTG evaluated the safety and efficacy of medications to fight HIV and related infections, and evaluated how treatments for HIV should be combined. This research has provided the basis for FDA approval of new anti-HIV drugs for children and the development of clinical guidelines to help doctors treat HIV-positive children and adolescents.
Through the Adolescent Initiative, the PACTG carried out important studies on adolescent research priorities, such as strengthening the immune systems of HIV-positive adolescents, simplifying treatment regimens, and learning how puberty impacts the effectiveness of anti-HIV treatments.
The PACTG has launched initiatives to enable mid-developed countries to participate in collaborative research trials, providing clinical data, expertise and laboratory support to help local researchers design, implement, and analyze large-scale studies.