Malaria Elimination Surveillance in Swaziland: Investigation of Strategies to Improve Sensitivity and Efficiency for Detection of Secondary Cases
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Investigator: Michelle Hsiang, MD
Sponsor: American Society of Tropical Medicine and Hygiene
Location(s): Swaziland
Description
To guide malaria elimination efforts in Swaziland and other countries, accurate assessments of transmission are critical. Pooled-PCR has potential to efficiently improve sensitivity to detect infections; serology may clarify temporal and spatial trends in exposure.
The prevalence of malaria infection and recent exposure in Swaziland are extremely low, suggesting elimination is feasible. Future efforts should address imported malaria and target remaining foci of transmission. Pooled PCR and ELISA are valuable surveillance tools for guiding elimination efforts.