Non-communicable diseases are no longer diseases of the rich. Hypertension is the leading risk factor for the global burden of disease. If hypertension is targeted in South Asia, premature mortality will decrease by 18%. The rural population of Tamil Nadu, India has high rates of hypertension at 21%, with only 7% in control of their blood pressure. Adherence to hypertension medication is a major issue among rural communities due to a lack of knowledge and awareness about hypertension. Discovering specific barriers and facilitators to low medication adherence in rural Sittlingi, Tamil Nadu, can have implications in effectively treating rural populations.