FIND Xpert MTB assay collaboration at Mulago Hospital
Investigator: Laurence Huang, MD
Sponsor: Foundation for Innovative New Diagnostics
To determine the diagnostic accuracy and impact of Xpert MTB/RIF among high-risk TB suspects.
We prospectively enrolled consecutive, hospitalized, Ugandan TB suspects in two phases: baseline phase in which Xpert MTB/RIF results were not reported to clinicians and an implementation phase in which results were reported. We determined the diagnostic accuracy of Xpert MTB/RIF in reference to culture (solid and liquid) and compared patient outcomes by study phase.