Evaluation of Point-of-Care C-reactive Protein Assay as a Serial Screening Tool for Active Tuberculosis among People Living with HIV in Uganda

Investigator: Paul Park, MS
Sponsor: Global Health Sciences Education

Location(s): Uganda


Mentor: Dr. Christina Yoon 

Intensified case finding (ICF) is recommended for all PLHIV at every clinic visit. Previously, we demonstrated that ICF has similar yield but would require half as many Xpert MTB/RIF confirmatory tests if TB screening were based on point-of-care C-reactive protein (POC CRP) levels instead of symptoms. Here, we compare the same ICF strategies when repeated at 3 months.