Come As You Are - Assessing the Efficacy of a Nurse Case Management HIV Prevention and Care Intervention among Homeless Youth
Location(s): United States
Few HIV prevention programs prioritize the unique HIV prevention needs of youth experiencing homelessness (YEH) including access to and engagement in the full continuum of behavioral and biomedical HIV prevention methods, particularly PrEP and nPEP. There is a critical need to test theory-based, youth-friendly HIV prevention interventions among YEH that are personalized, relevant to youth, and scalable. Guided by the Comprehensive Health Seeking and Coping Framework, the goal of this study is to conduct a randomized controlled trial of an enhanced NCM intervention, NCM4HIV, delivered to YEH 16-25 years old in collaboration with health and social service providers to assess the intervention impact on the uptake and adherence to HIV prevention strategies. If found to be efficacious, this scalable intervention will advance the field of HIV prevention among homeless youth by increasing access to behavioral and biomedical HIV prevention.
Aim 1 : Determine whether the enhanced NCM intervention increases uptake of HIV prevention strategies (PrEP and nPEP uptake, HIV testing, STI screening and treatment, and condom use) when compared with usual care received by YEH (N=450; aged 16-25 years).
Aim 2 : Determine whether NCM4HIV improves mental health, substance use, and housing status when compared with control youth at baseline, immediate post and 3, 6, and 9 months.