AIDS Clinical Trials Group: REPRIEVE Trial (A5332 and A5333s)

Investigator: Diane Havlir, MD
Sponsor: Massachusetts General Hospital

Location(s): United States


Randomized Trial to Prevent Vascular Events in HIV, or REPRIEVE, is the largest to date focused on HIV-related cardiovascular disease. Researchers hypothesize that statins should reduce plaque development and improve cardiovascular outcomes in patients with HIV. The ultimate objective of the trial is to inform the best clinical approach to preventing cardiovascular disease in people infected with HIV.