Genetics

Active Projects: 31

Project Investigator All Topics Start date End date
Extending ASD risk locus discovery to the non-coding genome Genetics, Neurology and Mental Health
Identification of Causal Variants in Psoriasis Wilson J. Liao, MD Genetics
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Policy, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, International Health Policy, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training
Newborn Screening Program for Sickle Cell James Huang, MD Genetics, Newborn and Infant Health
Pharmacogenomics of Bronchodilator Response in Minority Children with Asthma Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pharmacology and Drug Treatment, Pediatrics
BMI Bioinformatics Training Grant Patricia C. Babbitt, PhD Genetics, Residencies, Fellowships, and Postdoctoral Training
A Program of Research in Population Cytogenetics Tracey Woodruff, PhD, MPH Occupational and Environmental Disease, Genetics, Newborn and Infant Health
Molecular and Cellular Mechanisms of Synaptic Growth Genetics
1 of 7 Epi4K: Gene discovery in 4,000 epilepsy genomes - Administrative Core Daniel H. Lowenstein, MD Genetics, Neurology and Mental Health
Molecular Genetics of Liver Cancers Xin Chen, PhD Cancer/Oncology, Genetics
Center for RNA Systems Biology Jonathan S. Weissman, PhD Immunology, Genetics, Pharmacology and Drug Treatment
The Genetic Basis of Pediatric Cholestasis Laura N. Bull, PhD Genetics, Newborn and Infant Health
Validation of candidate ASD genes by targeted sequencing with molecular inversion probes Genetics, Neurology and Mental Health
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse Children Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics, Pediatrics
Metagenomic Contributions to Type 2 Diabetes Among Filipino Populations Mark Seielstad, PhD Diabetes, Genetics
Gene regulation and function in early embryos Thomas B. Kornberg, PhD Genetics
Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming Jonathan S. Weissman, PhD Genetics
Towards detailed and consistent function prediction from protein family databases Patricia C. Babbitt, PhD Genetics
Molecular basis of tissue interactions that regulate craniofacial development Ralph S. Marcucio, PhD Genetics
Massively Parallel Identification of Causative 3´ UTR Variants in Asthma David J. Erle, MD Chronic Respiratory Disease, Genetics
UCSF Team, The genetic, epigenetic, and immunological underpinnings of cancer evolution through treatment Steven J. Altschuler, PhD Cancer/Oncology, Genetics
The Genetics of Glaucoma in African Americans Neil J. Risch, PhD Eye Disease and Blindness, Genetics
Integrated Training in Reproductive Sciences Synthia Mellon, PhD Sexually Transmitted Infections (STIs), Genetics, Family Planning, Residencies, Fellowships, and Postdoctoral Training
Taking It to the Next Level: Measuring and Modeling Effects of Inter-Individual Protein-Level Buffering on Phenotypic Penetrance of DNA Copy Number Variants Genetics
Richer Models of Asthma Risk: Bridging the Environment-Genetics Divide Noah A. Zaitlen, PhD Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics
Integrative Program in Complex Biological System (ipCBS) Joseph L. Derisi, PhD Drug and Diagnostics Development, Immunology, Genetics, Residencies, Fellowships, and Postdoctoral Training
ACC: Callosal Agenesis as a Window into Common Neurodevelopment Disorders Elliott H. Sherr, MD, PhD Genetics, Neurology and Mental Health, Dementia and Cognitive Impairment
Gene linkage study of multiple sclerosis sibling pairs Stephen L. Hauser, MD Genetics, Neurology and Mental Health
Phase 2, Parallel-Arm Study of MGCD265 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Activating Genetic Alterations in Mesenchymal-Epithelial Transition Factor Cancer/Oncology, Genetics, Pharmacology and Drug Treatment
UC Valley Fever Research Initiative Anita Sil, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Genetics
Genes, air pollution, and asthma severity in minority children Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Genetics

Active Projects: 90

Project Investigator All Topics Start date End date
Genetic Risk Factors for Pneumonia in SLE Lindsey A. Criswell, MD, MPH Noncommunicable and/or Chronic Disease, Genetics
Population Genetics of the PO1 Locus of SIV and HIV-1 Eric L. Delwart, PhD HIV/AIDS, Genetics
Examination of genome instability in Plasmodium Falciparum using functional genomics Malaria, Genetics
The Genetic Epidemiology of RA and SLE Lindsey A. Criswell, MD, MPH Noncommunicable and/or Chronic Disease, Genetics, Epidemiology and Surveillance, UCSF Professional Education, Patient and Peer Education
Herpesviral Gene Expression in Kaposi's Sarcoma Donald E. Ganem, MD HIV/AIDS, Cancer/Oncology, Genetics
Double-Stranded RNA Virus in Giardia Ching C. Wang, MD Genetics
Elite Controllers Steven G. Deeks, MD HIV/AIDS, Immunology, Genetics
Admixture Mapping Development and Testing in African American SLE Lindsey A. Criswell, MD, MPH Genetics
Case-Control Association Studies and Genetic Confounding Esteban G. Burchard, MD, MPH Genetics, Risk Reduction and Prevention
NK Cell Receptors and Their Ligands Lewis L. Lanier, PhD Immunology, Genetics
Novel Strategies for defining the Role of HLA in SLE Lindsey A. Criswell, MD, MPH Noncommunicable and/or Chronic Disease, Genetics
Population Genetic Mapping of Tourette Syndrome Victor I. Reus, MD Genetics, Neurology and Mental Health
Genetics of Schizophrenia in Oceanic Palau William F. Byerley, MD Genetics, Neurology and Mental Health, Pediatrics
UCSF/Ragon Collaboration on HIV "Elite" Controllers Steven G. Deeks, MD HIV/AIDS, Drug and Diagnostics Development, Immunology, Genetics
Siglec-F and Resolution of Allergic Inflammation Homer A. Boushey, MD Immunology, Genetics
Pharmacogenomics of Antimalarial Drugs Sunil Parikh, MD, MPH Malaria, Genetics, Pharmacology and Drug Treatment
Dissecting the HLA Contribution to Rheumatoid Arthritis Lindsey A. Criswell, MD, MPH Genetics
Dissecting the HLA contribution to Rheumatoid Arthritis Lindsey A. Criswell, MD, MPH Genetics
Bipolar Endophenotypes in Population Isolates Victor I. Reus, MD Genetics, Neurology and Mental Health
Neurosteroids in Health and Disease Synthia Mellon, PhD Genetics, Neurology and Mental Health
Secretion of Virulence Factors by Mycobacterium tuberculosis Infectious Disease, HIV/AIDS, Tuberculosis, Genetics
Epigenetic Profiling of Multiple Cell and Tissue Types in Sjögren's Syndrome Lindsey A. Criswell, MD, MPH Genetics
RNAi as an Intercellular Antiviral Defense Mechanism Raul Andino-Pavlovsky, PhD Infectious Disease, Genetics
Identifying Intermediate Phenotypes for Compulsive Hoarding Carol A. Mathews, MD Genetics, Neurology and Mental Health
Translation Regulation in Giardia lamblia Ching C. Wang, MD Infectious Disease, Genetics
Escaneo genomico completo del paciente con diabetes tipo 2 para la busqueda de nuevos marcadores de asociacion con enfermedad Esteban G. Burchard, MD, MPH Diabetes, Genetics
POPGEN: Population Genetics Haplotype Estimation Method in Complex Typing Data Pierre-Antoine Gourraud, PhD Noncommunicable and/or Chronic Disease, Genetics
Whole Genome Sequencing of Multiplex Schizophrenia Pedigrees from an Isolated Population William F. Byerley, MD Genetics, Neurology and Mental Health
GEAR-Genetics and the Environment Associated with Male Reproduction Laurence S. Baskin, MD Occupational and Environmental Disease, Genetics
Pharmacogenetics of Chemotherapy-Induced Toxicity in Breast Cancer Deanna L. Kroetz, PhD Cancer/Oncology, Genetics, Pharmacology and Drug Treatment, Women's Health
CANCELED - Gene regulation and function in early embryos (2 R01 HD072046-01A1) Thomas B. Kornberg, PhD Genetics
Single Molecule DNA Mapping for DNA and CNV Analysis Pui-Yan Kwok, MD, PhD Genetics
An Open-Label, Multicenter Study Evaluating the Safety and Tolerability of Once-Daily Oral Aripiprazole in Children and Adolescents with Tourette's Disorder R. Keith McBurnett, PhD Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health
Whole Genome Analyses for Asthma in Latino Populations Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics
Public Health Research, Epidemiology, and Surveillance for Hemoglobinopathies (PHRESH) Sickle Cell Disease (SCD)/ Thalassemia Case Reporting James Huang, MD Infectious Disease, Genetics, Health Systems Strengthening, Risk Reduction and Prevention
Genetic Diversity as a Determinant of Viral Pathogenesis and Attenuation Raul Andino-Pavlovsky, PhD Infectious Disease, Genetics, Risk Reduction and Prevention
Lysosomal Storage Disorders Genetic Counselor Fellowship (Genzyme 43737) Seymour Packman, MD Noncommunicable and/or Chronic Disease, Genetics, Pediatrics
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach Nevan J. Krogan, PhD, MSc Noncommunicable and/or Chronic Disease, Cancer/Oncology, Genetics
The Epilepsy Phenome/ Genome Project (EPGP) [I] Daniel H. Lowenstein, MD Genetics
Fellowship in Clinical Biochemical Genetics Seymour Packman, MD Genetics, Residencies, Fellowships, and Postdoctoral Training
Effects of CCR5 - delta-32 Heterozygosity on the HIV-1 Reservoir Steven G. Deeks, MD HIV/AIDS, Immunology, Genetics
Collaborative Molecular Genetic Investigation of Pediatric Myelodysplatic Syndromes Mignon Loh, MD Genetics, Neurology and Mental Health
Computational and Functional Annotation of the Zebrafish Genome Regulatory Toolbox Nadav Ahituv, PhD Genetics
Epi4K: Gene discovery in 4,000 Epilepsy Genomes (4/7) Elliott H. Sherr, MD, PhD Cardiovascular Disease, Genetics
Whole Genome Sequencing in Multiple Sclerosis Jorge Oksenberg, PhD Genetics
Massively Parallel Functioning Testing of Regulatory Elements in Vivo Nadav Ahituv, PhD Immunology, Genetics
Molecular Genetics of Liver Cancers Xin Chen, PhD Cancer/Oncology, Genetics
Characterization of Regulatory Elements Leading to Human Limb Malformations Nadav Ahituv, PhD Noncommunicable and/or Chronic Disease, Genetics
Preventing Fucose-Dependent Binding of Aspergillus and Pseudomonas to Lung Mucin John V. Fahy, MD Infectious Disease, Chronic Respiratory Disease, Genetics
Mobile Phone Platform for Genomic Disease Detection Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Genetics
An optogenetic method to rapidly and reversibly titrate protein levels in cells Orion D. Weiner, PhD Genetics
PAAR4Kids-Pharmacogenomics Research Network Mignon Loh, MD Cancer/Oncology, Genetics, Pharmacology and Drug Treatment
Risk of Leukemia after Protracted Exposures to Low Doses of Ionizing Radiation. Lydia Zablotska, MD, MPA, PhD Noncommunicable and/or Chronic Disease, Cancer/Oncology, Genetics, Epidemiology and Surveillance, Risk Reduction and Prevention
The Amyotrophic Lateral Sclerosis (ALS)/Parkinsonism-Dementia Complex of Guam: Exploring the Mechanism of a Rare Tauopathy Michael D. Geschwind, MD, PhD Genetics, Neurology and Mental Health
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes (1/7) Daniel H. Lowenstein, MD Genetics
Mechansims of poliovirus replication Raul Andino-Pavlovsky, PhD Infectious Disease, Noncommunicable and/or Chronic Disease, Genetics
High throughput proteomics to dissect Chlamydia-host cell interactions Joanne N. Engel, MD, PhD Infectious Disease, Sexually Transmitted Infections (STIs), Genetics, Risk Reduction and Prevention
Transthyretin-Associated Amyloidoses Outcomes Survey (THAOS) (Survey ID: Fx-R-001) Jeffrey W. Ralph, MD Genetics, Neurology and Mental Health
An Evolutionary-Developmental Approach to Stem Cells Using Teeth As a Model Ophir Klein, MD, PhD Oral Health, Genetics, Training International Scholars and Clinicians
Dissecting Epistasis and Pleiotropy in Autism Towards Personalized Medicine Lauren A. Weiss, PhD Genetics, Risk Reduction and Prevention
Alfred P. Sloan Foundation Fellowship Ryan Hernandez, PhD Genetics
Identifying and targeting HIV persistence in T Cell subsets during ART Steven G. Deeks, MD Drug and Diagnostics Development, Immunology, Genetics
A Multicenter, Randomized, Placebo-Controlled Study of SBC-102 in Patients with Lysosomal Acid Lipase Deficiency John P. Kane, MD, PhD Genetics
Philippine-UC Collaboratory for Device Innovation (Education/Training Award) Michael R. Harrison, MD Zoonosis, Emerging Disease, and Drug Resistance, Malaria, Drug and Diagnostics Development, Genetics, Training International Scholars and Clinicians
Genetic Studies of Cortex Structure and Development John L. Rubenstein, MD, PhD Genetics, Neurology and Mental Health
The Role of Continuous Phenotypic Variation in Structural Defects of the Face Ralph S. Marcucio, PhD Genetics, Newborn and Infant Health
A Systems-Level Approach to Studying HIV/AIDS Susceptibility and Substance Abuse Sourav Bandyopadhyay, PhD HIV/AIDS, Genetics
Genetic Architecture of Complex Traits in Admixed Populations Neil J. Risch, PhD Genetics
Integrating computation and genetics to quantify specificity in protein networks Nevan J. Krogan, PhD, MSc Genetics
Characterization of Familial Advanced Sleep Phase Syndrome Louis J. Ptacek, MD Genetics
Genetic Determinants of Capecitabine Toxicity Hope Rugo, MD Genetics, Pharmacology and Drug Treatment
Genetic Disease Laboratory and Genetic Disease Screening Program on Clinical Laboratory Improvement Amendments (CLIA) 15-10151 Alan H. Wu, PhD Genetics
Accurate, long-read sequencing with droplet-microfluidic barcoding Adam Abate, PhD Infectious Disease, Cancer/Oncology, Genetics
Protein homeostasis mechanisms underlying enterovirus replication and evolution Raul Andino-Pavlovsky, PhD Genetics
Synthetic Biology Engineering Research Center (SynBERC) Wendell A. Lim, PhD Drug and Diagnostics Development, Genetics, Pharmacology and Drug Treatment
Assessing transgenerational effects of Pthalates on primordial germ cells Diana J. Laird, PhD Genetics, Pediatrics, Newborn and Infant Health
Genomic Analysis in Narcolepsy-Cataplexy Neil J. Risch, PhD Genetics, Neurology and Mental Health
Developmental and Hyperactive Ras Tumor SPORE Kevin M. Shannon, MD Cancer/Oncology, Genetics
Genetics of Mammographic Density in Ashkenazi Jews Elad Ziv, MD Cancer/Oncology, Genetics
Genome wide association study of breast cancer subtype and survival in Latinas Laura Fejerman, PhD Cancer/Oncology, Genetics, Epidemiology and Surveillance
New York Center for Collaborative Research in Common Disease Genomics Esteban G. Burchard, MD, MPH Genetics
Molecular Basis for Transmembrane Conduction and Signaling Robert M. Stroud, PhD Genetics
Molecular genetic, host-derived and clinical determinants of long-term survival in glioblastoma Jennifer L. Clarke, MD, MPH Cancer/Oncology, Genetics
Role of SOX2 O-GIcNAcylation in pluripotency Genetics
Genetic and epigenetic contributions to Sjogrens syndrome Lindsey A. Criswell, MD, MPH Eye Disease and Blindness, Oral Health, Genetics
Genetic and molecular pathophysiology of ATS Louis J. Ptacek, MD Cardiovascular Disease, Genetics
Risk-Benefit Trade-Offs for Whole Genome Sequencing Kathryn A. Phillips, PhD Genetics
Translational Investigation of KRas & NF1 in Myeloid Leukemia Kevin M. Shannon, MD Cancer/Oncology, Genetics
Genetic Predictors of Bevacizumab Toxicity in CALGB 80405 Deanna L. Kroetz, PhD Genetics, Pharmacology and Drug Treatment
Center for Multi- and Trans-ethnic Mapping of Mendelian and Complex Diseases Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pediatrics