Department of Cellular and Molecular Pharmacology

Active Projects: 29

Project Investigator All Organizations Start date End date
Influence of Heme on Hepatic Cytochrome P450 Turnover Maria A. Correia, PhD Department of Cellular and Molecular Pharmacology
The PIP2-Virus Interface and PI 4-Kinase: Novel Biology and Validation Targets Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
A systems-level approach in HIV/AIDS susceptibility and substance abuse Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Clinical and Molecular Phenotypes of Severe Asthma John V. Fahy, MD Department of Cellular and Molecular Pharmacology
Gene Regulation by Steroid Receptor Proteins Keith Yamamoto, PhD Department of Cellular and Molecular Pharmacology
Relationships between Alcohol, Patient Characteristics, and Atrial Fibrillation Isaac R. Whitman, MD Department of Cellular and Molecular Pharmacology
Optogenetic dissection of the growth and activation network in T cells Department of Cellular and Molecular Pharmacology
Center for RNA Systems Biology Jonathan S. Weissman, PhD Department of Cellular and Molecular Pharmacology
Comparative Analysis of Genetic Interaction Networks Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming Jonathan S. Weissman, PhD Department of Cellular and Molecular Pharmacology
HINT: HIV Immune Networks Team Modeling Core Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology, AIDS Research Institute
Physical and Genetic Interaction Landscape of the Tyrosine Kinome Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Tobacco/Marijuana Smoke: From Lab to Public Health Policy Matthew Springer, PhD Department of Cellular and Molecular Pharmacology
Synthetic biology of yeast Wendell A. Lim, PhD Department of Cellular and Molecular Pharmacology
Collaborative Research: Molecular Programming Architectures, Abstractions, Algorithms, and Applications Shawn M. Douglas, PhD Department of Cellular and Molecular Pharmacology
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
Structure and mechanism of the dyein motor Ronald D. Vale, PhD Department of Cellular and Molecular Pharmacology
Hepatic degradation of cytochrome P450 enzymes Maria A. Correia, PhD Department of Cellular and Molecular Pharmacology
Transporters for Glucocorticoids: Exploring a New Paradigm for Steroid Hormone Regulation, and a Potential Strategy for Identification of Toxin/Disruptor Transporter Machineries Keith Yamamoto, PhD Department of Cellular and Molecular Pharmacology
Antibody Repertoire Diversity in CVD, Aging, Death in a Large Multi-Ethnic Cohort Shaun R. Coughlin, MD, PhD Department of Cellular and Molecular Pharmacology
Nanoscale Devices for Targeted Delivery of Combination Therapies Shawn M. Douglas, PhD Department of Cellular and Molecular Pharmacology
Structural and Functional Studies of HER Receptor Tyrosine Kinases Natalia Z. Jura, PhD Department of Cellular and Molecular Pharmacology
Allosteric Regulation in the KDM5 Family of Histone Demethylases Fujimori Danica Galonic, PhD Department of Cellular and Molecular Pharmacology
Drugging the Switch-II Pocket of K-Ras Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
Redesigning the T cell: Using Synthetic Biology to Engineer Therapeutic Cells Wendell A. Lim, PhD Department of Cellular and Molecular Pharmacology
CAREER: Programming digital bits with DNA for barcoded nanoscale imaging applications Shawn M. Douglas, PhD Department of Cellular and Molecular Pharmacology
Genetic and chemical biological studies of K2P structure, function, and modulation Daniel Minor, JR, PhD Department of Cellular and Molecular Pharmacology
Prevention and Early Treatment of Acute Lung Injury Michael A. Matthay, MD Department of Cellular and Molecular Pharmacology
Postdoctoral training in tobacco control Pamela M. Ling, MD Department of Cellular and Molecular Pharmacology

Archived Projects: 37

Project Investigator All Organizations Start date End date
Targeting Malaria via Inhibition of Plasmodium Falciparum Enoyl-ACP Department of Cellular and Molecular Pharmacology
A Chemical Map of T Cell Signaling Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
Affinity Isolation of Direct Kinase Substrates Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
ARABIDOPSIS 2010: Affinity Handle on Macromolecular Complexes Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Identification of Hypothemycin Targets in T. brucei Jack W. Taunton, PhD Department of Cellular and Molecular Pharmacology
A Kinase-Substrate Cross linker for Mapping Signaling Pathsays in Reverse Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Host-pathogen quantitative protein-protein and genetic interaction mapping Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Comparative Analysis of Genetic and Physical Interaction Networks in Yeasts Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Global Innate Immune Responses to HIV-1 Infection Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Systems-Based Analysis of Flaviviral Host Restriction Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Building the Foundation for a Science-Community Partnership to Address the Early Roots of Racial and Ethnic Disparities in Health Michelle A. Albert, MD, MPH Department of Cellular and Molecular Pharmacology
Building the Foundation for a Science-Community Partnership to Address the Early Roots of Racial and Ethnic Disparities in Health Michelle A. Albert, MD, MPH Department of Cellular and Molecular Pharmacology
Regulation and Function of a Bacterial Cytoskeleton R. Dyche Mullins, PhD Department of Cellular and Molecular Pharmacology
Integrating computation and genetics to quantify specificity in protein networks Nevan J. Krogan, PhD, MSc Department of Cellular and Molecular Pharmacology
Large-Scale Production and In-Vivo Characterization of Therapeutic DNA Nanodevices Shawn M. Douglas, PhD Department of Cellular and Molecular Pharmacology
Exploring Design Principles of Cellular Control Circuits Wendell A. Lim, PhD Department of Cellular and Molecular Pharmacology
Designing Selective Inhibitors of Calcium-Dependent Kinases in Parasites Kevan Shokat, PhD Department of Cellular and Molecular Pharmacology
Synthetic Biology Engineering Research Center (SynBERC) Wendell A. Lim, PhD Department of Cellular and Molecular Pharmacology
Task Order #8 Alendronate for Asthma Stephen C. Lazarus, MD Department of Cellular and Molecular Pharmacology
Cumulative Stress and CVD Risk in Middle-Aged And Older Women Michelle A. Albert, MD, MPH Department of Cellular and Molecular Pharmacology
Task Order #7 Steroids in Eosinophil Negative Asthma (SIENA) Stephen C. Lazarus, MD Department of Cellular and Molecular Pharmacology
Self-Assembled DNA Devices for Nanoscale Manipulation of Immune Signal Transduction Shawn M. Douglas, PhD Department of Cellular and Molecular Pharmacology
Programing Biomolecular Nanodevices For Targeted Immune Cell Recognition and Payload Delivery Shawn M. Douglas, PhD Department of Cellular and Molecular Pharmacology
Protein Recognition in Signal Transduction Wendell A. Lim, PhD Department of Cellular and Molecular Pharmacology
HGV2014/2015 International Meetings on Human Genome Variation and Complex Genome Analysis Pui-Yan Kwok, MD, PhD Department of Cellular and Molecular Pharmacology
Microtubule Complexes Involved in Intracellular Transport Ronald D. Vale, PhD Department of Cellular and Molecular Pharmacology
Open Source Microscopy Software Ronald D. Vale, PhD Department of Cellular and Molecular Pharmacology
iBioSeminars: A Web-Based Educational Resource for Biologists Ronald D. Vale, PhD Department of Cellular and Molecular Pharmacology
Exploration of the Host Genetic Interactions Underlying HIV Infectivity David Gordon, PhD Department of Cellular and Molecular Pharmacology
Creating an online resource center for training and professional development in the biomedical sciences Ronald D. Vale, PhD Department of Cellular and Molecular Pharmacology
Enhancing biomedical training and diversity through a Hispanic science network Ronald D. Vale, PhD Department of Cellular and Molecular Pharmacology
Molecular basis for the activation of Met receptor in lung cancer by mutations in the juxtamembrane segment Natalia Z. Jura, PhD Department of Cellular and Molecular Pharmacology
Medtronic - 2015 EP Fellowship 20141212 RB Nitish Badhwar, MD Department of Cellular and Molecular Pharmacology
Overcoming impairment of bone marrow cell therapy for myocardial infarction: Role of B cells Matthew Springer, PhD Department of Cellular and Molecular Pharmacology
Mechanisms and Therapeutics for Glucocorticoid-Resistant Leukemia Keith Yamamoto, PhD Department of Cellular and Molecular Pharmacology
Synaptic Glutamate Receptor Trafficking Roger Nicoll, MD Department of Cellular and Molecular Pharmacology, Department of Pediatrics