Department of Neurology

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Active Projects: 42

Project Investigator All Organizations Start date End date
The Coagulation Cascade as a Biomarker and Therapeutic Target for Progressive Multiple Sclerosis Jorge Oksenberg, PhD Department of Neurology
Effect of Passive Immunization on the Progression of Mild Alzheimer's Disease: Solanezumab(LY2062430) versus Placebo Adam L. Boxer, MD, PhD Memory and Aging Center
Predicting Stroke after Trauma (PSAT) Heather J. Fullerton, MD Neurocritical Care and Stroke Research
Transatlantic Network on Newborn Stroke: Inflammatory Modulation of Neurovascular Injury Donna M. Ferriero, MD Neonatal Brain Disorders Laboratory
Molecular genetic, host-derived and clinical determinants of long-term survival in glioblastoma Jennifer L. Clarke, MD, MPH Department of Neurology
Genetic and molecular pathophysiology of ATS Louis J. Ptacek, MD Department of Neurology
Extension of Phase II Studies ABE4869g and ABE4955g in Patients with Mild to Moderate Alzheimer Disease Adam L. Boxer, MD, PhD Memory and Aging Center
Genetic network analysis of cancer targets William Weiss, MD, PhD Department of Neurology
Burden, Depression, and Health in Dementia Caregivers: the Role of Emotion Bruce L. Miller, MD Memory and Aging Center
Frontotemporal Dementia: Genes, Images, and Emotions Bruce L. Miller, MD Memory and Aging Center
SF-NETT: San Francisco Neurological Emergencies Trials Network J. Claude Hemphill, MD Department of Neurology
A Novel Cognitive Brain Computer Interface (cBCI) for Attention Deficit Disorder Jyoti Mishra, PhD Global Health Sciences Faculty Affiliate, Department of Neurology
Fingolimod Administered Orally Once Daily vs Interferon Beta-1a i.m. Once Weekly in Pediatric Patients with Multiple Sclerosis Emmanuelle L. Waubant, MD, PhD Department of Neurology
The Human Epilepsy Project (HEP) Daniel H. Lowenstein, MD Department of Neurology
ALS Center of Excellence at UCSF Catherine E. Lomen-Hoerth, MD, PhD Department of Neurology
Murine Neuroblastoma Models for Preclinical Therapeutics William Weiss, MD, PhD Department of Neurology
1 of 7 Epi4K: Gene discovery in 4,000 epilepsy genomes - Administrative Core Daniel H. Lowenstein, MD Department of Neurology
The UCSF and UNMC Dementia Care Ecosystem: Using Innovative Technologies to Personalize and Deliver Coordinated Dementia Care Bruce L. Miller, MD Memory and Aging Center
Futility Study of Deferoxamine in Intracerebral Hemorrhage "DIMINIsH" Vineeta Singh, MD Department of Neurology
Characterization of Novel MOG T Cell Epitopes Shared in Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS) Scott Zamvil, MD, PhD Department of Neurology
ENROLL-HD -A Prospective Registry Study in a Global Huntington's Disease Cohort Michael D. Geschwind, MD, PhD Memory and Aging Center
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
A Single Arm, Open-Label, Multicenter Study Evaluating the Long-Term Safety, Tolerability and Efficacy of 0.5 Mg Fingolimod (Fty720) Administered Orally Once Daily in Patients with Multiple Sclerosis (MS) Douglas S. Goodin, MD Department of Neurology
Therapeutic Interventions during Acute Infection to Address the CNS Reservoir for HIV Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Multimodal Imaging in Frontotemporal Degeneration Howard J. Rosen, MD Memory and Aging Center
Predicting Progression of Human Prion Disease Michael D. Geschwind, MD, PhD Memory and Aging Center
A Double-Blind, Placebo-Controlled, Randomized, Parallel Group, 12-Month Safety and Efficacy Trial of Leuco-methylthioninium bis(hydromethanesulfonate) in Subjects with Behavioral Variant Frontotemporal Dementia (bvFTD) Adam L. Boxer, MD, PhD Memory and Aging Center
New Approaches to Dementia Heterogeneity (P50) Bruce L. Miller, MD Memory and Aging Center
Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) Howard J. Rosen, MD Memory and Aging Center
Interventions for Symptom Management in Older Patients with HAND Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center, AIDS Research Institute
MYCN, mTOR and translation control in medulloblastoma William Weiss, MD, PhD Department of Neurology
National Alzheimer's Coordinating Center, NACC (Renewal for Y16-20) Bruce L. Miller, MD Memory and Aging Center
The Frontotemporal Lobar Degeneration Clinical Research Consortium Adam L. Boxer, MD, PhD Memory and Aging Center
Determinants of Resilience on Youth with HIV Infection and Youth Affected by HIV Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Multidisciplinary Fellowship in Dementia Research Bruce L. Miller, MD Memory and Aging Center
Regulation of cortical progenitors by Sufu and Shh signaling Samuel Pleasure, MD, PhD Department of Neurology
Gene linkage study of multiple sclerosis sibling pairs Stephen L. Hauser, MD Department of Neurology
The Jackson Laboratory Center for Precision Genetics: From New Models to Novel Therapeutics Daniel H. Lowenstein, MD Department of Neurology
Global Brain Health Institute Victor G. Valcour, MD, PhD Memory and Aging Center
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical Trajectories Memory and Aging Center
A Randomized, Double-Blind, Placebo-Controlled, SingleAscending Dose Study to Assess the Safety, Tolerability,and Pharmacokinetics of C2N-8E12 in Subjects withProgressive Supranuclear Palsy Adam L. Boxer, MD, PhD Memory and Aging Center
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center, AIDS Research Institute

Archived Projects: 131

Project Investigator All Organizations Start date End date
Seizure-induced Neurogenesis in the Mature CNS Daniel H. Lowenstein, MD Epilepsy Research Lab
California Acute Stroke Prototype Registry (CASPR) / Development of Prototypes for the Paul Coverdell National Acute Stroke Registry Neurocritical Care and Stroke Research
Warfarin Versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Study Department of Neurology
The Impact and Performance of NINDS-Sponsored Clinical Trials Neurocritical Care and Stroke Research
Optimizing Management of Transient Ischemic Attacks Department of Neurology
CASTIA Neurological Core Imaging Lab (NCIL) Neurocritical Care and Stroke Research
Antiplatelet Therapy for Ischemic Stroke and Transient Ischemic Attack in U.S. Community Hospitals Department of Neurology
Quality Improvement in Stroke Prevention (QUISP) Neurocritical Care and Stroke Research
NSA Guidelines Neurocritical Care and Stroke Research
Central Nervous System Events in Primary HIV Infection Department of Neurology
Cognitive Health and Brain Vulnerability in Aging Insulin Resistant Patients Victor G. Valcour, MD, PhD Memory and Aging Center
Development and Validation of a Diagnostic Tool for HIV Dementia Ana-Claire L. Meyer, MD Department of Neurology
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia Ana-Claire L. Meyer, MD Department of Neurology
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia Ana-Claire L. Meyer, MD Department of Neurology
CNS Immune / Inflammatory Biomarkers in HIV Controllers Richard W. Price, MD Department of Neurology
The role of infection in childhood stroke Heather J. Fullerton, MD Neurocritical Care and Stroke Research
MAPS: Matrix And Platinum Science, A Prospective, Randomized, Multicenter, Trial Investigating Matrix2 tm and GDC? Coils for the treatment of intracranial saccular aneurysms Trial Neurocritical Care and Stroke Research
Tracheostomy with Invasive Ventilation for Patients with Amyotrophic Lateral Sclerosis in Japan and USA: Comparative Study Catherine E. Lomen-Hoerth, MD, PhD ALS Center
HIV Neurocognitive Disorders: A Randomized Clinical Trial of CNS-Targeted HAART Department of Neurology
The Neuropathobiology of Primary HIV-1 Infection Richard W. Price, MD Department of Neurology
HIV Proteomics Center for Host Viral Response Characterization Richard W. Price, MD Department of Neurology
Dementia in HIV Patients over 60 Years of Age Victor G. Valcour, MD, PhD Memory and Aging Center
Expanded Access to MGAWN1 in Subjects with Suspected West Nile Neuroinvasive Disease; Substantial Exposure, or Infection and a Compromised Immune System Jeffrey W. Ralph, MD Department of Neurology
The Epilepsy Phenome/ Genome Project (EPGP) [II] Daniel H. Lowenstein, MD Epilepsy Research Lab
Point: Platelet-Oriented Inhibition in New TIA Neurocritical Care and Stroke Research
Neuroform Angiographic Analysis (Subset of MAPS study data) Neurocritical Care and Stroke Research
Parkinson Disease Neuroprotection Clinical Trial Michael J. Aminoff, MD, DSc Department of Neurology
DNA of Thai Male Thyrotoxic Patients and Family Members Louis J. Ptacek, MD Department of Neurology
Central Nervous System Effects in Acute HIV Seroconversion Victor G. Valcour, MD, PhD Memory and Aging Center
Pediatric Data Coordinating and Analysis Center Emmanuelle L. Waubant, MD, PhD Department of Neurology
POPGEN: Population Genetics Haplotype Estimation Method in Complex Typing Data Pierre-Antoine Gourraud, PhD Department of Neurology
Clinical Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis (ALS) Catherine E. Lomen-Hoerth, MD, PhD Department of Neurology
Targeted Treatment of Early Cryptococcal Infection in HIV-infected Patients Ana-Claire L. Meyer, MD Department of Neurology
Early Diagnosis of Human Prion Disease Michael D. Geschwind, MD, PhD Memory and Aging Center
HIV and Global Drug Therapies: Peripheral Neuropathy Complications and Mechanisms Victor G. Valcour, MD, PhD Memory and Aging Center
HIV-1 Specific Immune Responses in Thai Individuals with HIV Dementia Victor G. Valcour, MD, PhD Memory and Aging Center
Treatment of HIV-Associated Cognitive Impairment Ana-Claire L. Meyer, MD Department of Neurology
Salt intake and pediatric MS susceptibility Emmanuelle L. Waubant, MD, PhD Department of Neurology
DynSyst Special Topics: Mathematical Modeling of Nonlinear Dynamics and Bifurcation Control of Epileptic Seizures Heidi E. Kirsch, MD, MS Department of Neurology
Neuroprotection with Riluzole in Patients with Early Multiple Sclerosis (MS) Emmanuelle L. Waubant, MD, PhD Department of Neurology
Neurology Social Worker Services in Epilepsy Department of Neurology
Clinical and MRI features of NMO spectrum disorders in children Emmanuelle L. Waubant, MD, PhD Department of Neurology
Defective Forebrain Development in Mutant Mice Samuel Pleasure, MD, PhD Department of Neurology
MYCN and Medulloblastoma William Weiss, MD, PhD Department of Neurology
B Cells in Central Nervous System (CNS) Autoimmunity Scott Zamvil, MD, PhD Department of Neurology
Patient Management in Pediatric Onset Multiple Sclerosis (MS) Emmanuelle L. Waubant, MD, PhD Department of Neurology
Biomarker Optimization for Progranulin Trials (The BOPT Study) Adam L. Boxer, MD, PhD Memory and Aging Center
Stimulants and Childhood Stroke: a Population-Based Nested Case-Control Study Nancy K. Hills, PhD Global Health Sciences Faculty Affiliate, Neurocritical Care and Stroke Research
New Approaches to Dementia Heterogeneity Bruce L. Miller, MD Memory and Aging Center
Task Order #5: Bio-Protect Study - Neurological Emergencies Treatment Trials Network J. Claude Hemphill, MD Department of Neurology
The Epilepsy Phenome/ Genome Project (EPGP) [I] Daniel H. Lowenstein, MD Epilepsy Research Lab
Targeting the translational apparatus in MYCN-driven medulloblastoma William Weiss, MD, PhD Department of Neurology
Multiple Sclerosis International Federation Mcdonald Fellowship Department of Neurology
Neurological Sciences Academic Development Award (NSADA) (K12) Donna M. Ferriero, MD Neonatal Brain Disorders Laboratory
Clinical and biological markers of disease progression in familial FTD Howard J. Rosen, MD Memory and Aging Center
Epi4K: Gene discovery in 4,000 Epilepsy Genomes (4/7) Elliott H. Sherr, MD, PhD Department of Neurology
Neurobiological Predictors of Huntington's Disease (Predict-HD) Michael D. Geschwind, MD, PhD Memory and Aging Center
Establishing Therapeutic Efficacy in Frontotemporal Degeneration Howard J. Rosen, MD Memory and Aging Center
BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects with Mild Alzheimer's Disease Adam L. Boxer, MD, PhD Memory and Aging Center
Orexins and the Trigeminovascular System Peter J. Goadsby, MD, PhD Department of Neurology
Parkinson Disease Neuroprotection Clinical Trial Michael J. Aminoff, MD, DSc Department of Neurology
Defining CNS HIV Infection and Its Effects in Treated Patients: Foundation for Eradication Richard W. Price, MD Department of Neurology
Neurobiological Changes in Network Function and Amyloid Deposition in Alzheimer Disease Memory and Aging Center
Mechanisms of Ischemic Neonatal Brain Injury Donna M. Ferriero, MD Neonatal Brain Disorders Laboratory
Peripheral Reservoir of HIV Monocytes Pivotal to Cognition in HIV Victor G. Valcour, MD, PhD Memory and Aging Center
Aquaporin-4 (AQP4)-specific T Cells in CNS autoimmunity Scott Zamvil, MD, PhD Department of Neurology
The Pathobiology of Primary HIV-1 Infection Richard W. Price, MD Department of Neurology
Whole Genome Sequencing in Multiple Sclerosis Jorge Oksenberg, PhD Immunogenetics Laboratory
Eye Movement Control in Normal Elderly and MCI Adam L. Boxer, MD, PhD Memory and Aging Center
Gene Linkage Study of Multiple Sclerosis Sibling Pairs Stephen L. Hauser, MD Immunogenetics Laboratory
Predicting epilepsy after traumatic brain injury in children and young adults: A population based study Heather J. Fullerton, MD Department of Neurology
International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) Richard W. Price, MD Department of Neurology
Development of Resting-State FMRI As a Biomarker for Alzheimer Disease Bruce L. Miller, MD Memory and Aging Center
Validation of the ANI-SI Dry EEG Headset in Time-Critical Applications Daniel H. Lowenstein, MD Epilepsy Research Lab
The Efficacy of Intrathecal Baclofen for Spasticity in Primary Lateral Sclerosis Catherine E. Lomen-Hoerth, MD, PhD Department of Neurology
National Alzheimer's Coordinating Center, NACC Bruce L. Miller, MD Memory and Aging Center
Genetic Profiling of MS patients: The Multiple sclerosis genetic burden scoring methods compile the latest genetic associations¿ findings Pierre-Antoine Gourraud, PhD Department of Neurology
Task Order #3: Protect II Study - Neurological Emergencies Treatment Trial J. Claude Hemphill, MD Department of Neurology
An Open Label Dose Finding Study of Nimodipine for the Treatment of Frontotemporal Dementia Due to Progranulin Insufficiency From GRN Gene Mutations Adam L. Boxer, MD, PhD Memory and Aging Center
Prevention of Stroke after STOP Heather J. Fullerton, MD Neurocritical Care and Stroke Research
Educating Physician-Neuroscientists: The R25 at UCSF Stephen L. Hauser, MD Department of Neurology
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes (1/7) Daniel H. Lowenstein, MD Epilepsy Research Lab
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Sequential Cohort, Dose-Ranging Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TPI-287 in Patients with Mild to Moderate Alzheimer's Disease Adam L. Boxer, MD, PhD Memory and Aging Center
The Amyotrophic Lateral Sclerosis (ALS)/Parkinsonism-Dementia Complex of Guam: Exploring the Mechanism of a Rare Tauopathy Michael D. Geschwind, MD, PhD Memory and Aging Center
Cross-Sectional Examination of Cerebrospinal Fluid Kinetic Biomarkers of Axonal Transport for Amyotrophic Lateral Sclerosis (Als) Diagnosis and Progression Richard W. Price, MD Department of Neurology
Amitriptyline and Topiramate in the Prevention of Childhood Migraine Peter J. Goadsby, MD, PhD Department of Neurology
Transthyretin-Associated Amyloidoses Outcomes Survey (THAOS) (Survey ID: Fx-R-001) Jeffrey W. Ralph, MD Department of Neurology
A feasibility study of the transcranial Doppler breath-holding challenge to evaluate cerebral vasoreactivity in HIV-infected individuals in China Felicia C. Chow, MD Global Health Sciences Faculty Affiliate, Department of Neurology
U.S. Army Medical Research Acquisition Activity (USAMRAA) Victor G. Valcour, MD, PhD Memory and Aging Center
Non-Invasive Neurostimulation of the Vagus Nerve with the Gammacore Device for the Prevention of Chronic Migraine Peter J. Goadsby, MD, PhD Department of Neurology
Parkinson's Disease Neuroprotection Clinical Trial Michael J. Aminoff, MD, DSc Department of Neurology
Phase III Clinical Trial "Platelet Oriented Inhibition in New Tia" - Drug: Plavix Neurocritical Care and Stroke Research
Multi-Locus Sequence Typing Environmental Fungal Samples from Western Kenya Kristyn E. Feldman, PhD Department of Neurology
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of LY2951742 in Patients with Migraine Peter J. Goadsby, MD, PhD Department of Neurology
The Translational Alzheimer Disease Research Program Katherine L. Possin, PhD Memory and Aging Center
Neurodevelopment and Imaging among HIV-infected Children from the PREDICT Study Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
DoD-ADNI -Effects of TBI and PTSD on AD in Veterans using Imaging and Biomarkers in ADNI Howard J. Rosen, MD Memory and Aging Center
New Combination Therapies for Early Cryptococcal Infection in HIV Infected Individuals: A Randomized Controlled Trial Ana-Claire L. Meyer, MD Department of Neurology
Cellular and Genetic Basis of Anaplastic Medulloblastoma William Weiss, MD, PhD Department of Neurology
A Randomized Controlled Trial of Vitamin D Supplementation in Multiple Sclerosis Emmanuelle L. Waubant, MD, PhD Department of Neurology
Microbiomes in Pediatric MS Emmanuelle L. Waubant, MD, PhD Department of Neurology
Environmental and genetic risk factors for pediatric multiple sclerosis Emmanuelle L. Waubant, MD, PhD Department of Neurology
Infantile Spasms: Clinical and Genetic Predictors of Outcomes and Therapeutic Insights Elliott H. Sherr, MD, PhD Global Health Sciences Faculty Affiliate, Department of Neurology
Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression Catherine E. Lomen-Hoerth, MD, PhD Department of Neurology
HIV Tropism, Persistence, Inflammation, and Neurocognition in Therapy Initiation Richard W. Price, MD Department of Neurology
Four Repeat Tauopathy Neuroimaging Initiative Adam L. Boxer, MD, PhD Memory and Aging Center
Neurological Emergencies Treatment Trials: Clinical Coordinating Center (NETT CCC) Daniel H. Lowenstein, MD Epilepsy Research Lab
Characterization of Familial Advanced Sleep Phase Syndrome Louis J. Ptacek, MD Department of Neurology
Long-Term Central Nervous System (CNS) Consequences of Treatment during Acute Infection Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Creating Maps of 4D Brain Images to Unravel Dementia Heterogeneity of Aging HIV Population Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Department of Neurology
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Katherine L. Possin, PhD Memory and Aging Center
Selectively targeting delta opioid receptor subtypes to control drinking behavior Jennifer L. Whistler, PhD Department of Neurology
Pediatric Data Coordinating and Analysis Center Emmanuelle L. Waubant, MD, PhD Department of Neurology
Nancy Davis Collaborative Project to Fight Multiple Sclerosis (MS) Emmanuelle L. Waubant, MD, PhD Department of Neurology
Medical Student Research Training Fellowship Program Daniel H. Lowenstein, MD Department of Neurology
JCV Antibody Program in Patients with Relapsing Multiple Sclerosis Receiving or Considering Treatment with Tysabri®: Stratify-2 Douglas S. Goodin, MD Department of Neurology
SOCRATES - Acute Stroke Or Transient Ischaemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes Department of Neurology
Distinct Embryonic Origin for Postnatal Dentate Neural Stem Cells Samuel Pleasure, MD, PhD Department of Neurology
Samples from Brazilian Aging Brain Study Group Lea T. Grinberg, MD, PhD Memory and Aging Center
Study of Lytico-Bodig disease (Parkinson-dementia complex of Guam) William W. Seeley, MD Memory and Aging Center
VIPS: Vascular Effects of Infection in Pediatric Stroke Heather J. Fullerton, MD Neurocritical Care and Stroke Research
Stroke Hyperglycemia Insulin Network Effort (Shine) Trial Study; Task Order 6 J. Claude Hemphill, MD Department of Neurology
Phase I Multiple Ascending Dose Trial of the MT Stabilizer TPI-287 for Alzheimer Disease (AD) Adam L. Boxer, MD, PhD Memory and Aging Center
Phase II Study to Evaluate the Efficacy and Safety of MABT5102A in Patients with Mild to Moderate Alzheimer's Diseases Adam L. Boxer, MD, PhD Memory and Aging Center
Epi4K - Phenotyping and Clinical Informatics Core (U01) Daniel H. Lowenstein, MD Epilepsy Research Lab
The Frontotemporal Lobar Degeneration Neuroimaging Initiative Howard J. Rosen, MD Memory and Aging Center
Point: Platelet-Oriented Inhibition in New Transient Ischemic Attack (TIA) and Minor Ischemic Stroke Neurocritical Care and Stroke Research
Treatment Adherence in Pediatric Multiple Sclerosis: Project 5982896 Emmanuelle L. Waubant, MD, PhD Department of Neurology
The MS Bioscreen - Translational Digital Medicine for Multiple Sclerosis Stephen L. Hauser, MD Immunogenetics Laboratory
Causes, treatment and prevention of corticobasal degeneration Adam L. Boxer, MD, PhD Memory and Aging Center
Ancillary Study for DD Laquinimod Clinical Trial Scott Zamvil, MD, PhD Department of Neurology