Department of Pharmaceutical Chemistry

Archived Projects: 43

Project Investigator All Organizations Start date End date
Creating Polyketide Antibiotic Diversity by Engineering Cytochrome P450 Enzymes / UC Discovery Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Selective Destruction of Cytochrome P450 by Drugs Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Double-Stranded RNA Virus in Giardia Ching C. Wang, MD Department of Pharmaceutical Chemistry
Regulation of the Development of Tryanosoma brucei Ching C. Wang, MD Department of Pharmaceutical Chemistry
Biochemistry and Hepatic Toxicity of Carbon Radicals Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Regulation of the Development of Trypanosoma brucei Ching C. Wang, MD Department of Pharmaceutical Chemistry
Purine Metabolism in Trichomonas Vaginalis Ching C. Wang, MD Department of Pharmaceutical Chemistry
Hemoprotein Oxidation and Heme Catabolism Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Mechanism, Specificity, and Inhibition of Cytocchrome P450 Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Identification of Anti-HIV Lead Compounds Targeting Adam R. Renslo, PhD Department of Pharmaceutical Chemistry
Identification of Novel Small Molecule Therapeutics for Visceral Leishmaniasis Adam R. Renslo, PhD Department of Pharmaceutical Chemistry
Identification of Novel Small Molecule Therapeutics for Visceral Leishmaniasis Adam R. Renslo, PhD Department of Pharmaceutical Chemistry
Iron-Dependent Drug Delivery as a New Paradigm in Anti-Parasitic Chemotherapy and Prophylaxis Adam R. Renslo, PhD Department of Pharmaceutical Chemistry, Center for Discovery and Innovation in Parasitic Disease (CDIPD)
Investigation of M. tuberculosis Cytochrome P450 Involvement in Cholesterol Utilization Jonathan B. Johnston, PhD Department of Pharmaceutical Chemistry
Oxygen Sensors and P450 Monooxgenases in Mycobacterium tuberculosis Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Global Blood Targeting Matthew Jacobson, PhD Department of Pharmaceutical Chemistry
Identification of Novel Therapeutics Molecules against Old and New World Cutaneous Leishmaniasis Adam R. Renslo, PhD Department of Pharmaceutical Chemistry, Center for Discovery and Innovation in Parasitic Disease (CDIPD)
A Specific Mechanism for Non-Specific Inhibition Brian K. Shoichet, PhD Department of Pharmaceutical Chemistry
Translation Regulation in Giardia lamblia Ching C. Wang, MD Department of Pharmaceutical Chemistry
Chemical Methods for Ferrous Iron Targeted Drug Delivery Adam R. Renslo, PhD Department of Pharmaceutical Chemistry
A Web-Based Automatic Virtual Screening System Brian K. Shoichet, PhD Department of Pharmaceutical Chemistry
New treatments for triple negative breast cancer through the biparatopic inhibition of the uPAR receptor Department of Pharmaceutical Chemistry
The Physical Rules Governing Bilayer Self-Organization in the Human Mammary Epithelium Department of Pharmaceutical Chemistry
Physics-Based Simulation of Biological Structures Brian K. Shoichet, PhD Department of Pharmaceutical Chemistry
End-to-End Technology Validation of a Miniaturized, Automated Instrument for In Situ Measurement of Microbial Gene Expression in Space Michael R Wilson, MD Department of Pharmaceutical Chemistry
Regulation of the Development of Trypanosoma brucei Ching C. Wang, MD Department of Pharmaceutical Chemistry
Molecular Mechanisms of Bacterial Mercury Transformation Susan Miller, PhD Department of Pharmaceutical Chemistry
Automated System for High-Throughput in Vitro Selection of Recombinant Antibodies James Wells, PhD Department of Pharmaceutical Chemistry
Factor IX studies at UCSF for GBT Matthew Jacobson, PhD Department of Pharmaceutical Chemistry
QB3 Drug Discovery Michelle Arkin, PhD Department of Pharmaceutical Chemistry
Defining the Molecular-Cellular-Field Continuum of Mercury Detoxification Susan Miller, PhD Department of Pharmaceutical Chemistry
Hemoprotein Oxidation and Heme Catabolism Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Small Angle X-Ray and Neutron Scattering Studies of MER Enzymes Susan Miller, PhD Department of Pharmaceutical Chemistry
Characterizing Natural Product Permeability and Bioactivity Department of Pharmaceutical Chemistry
Structure, Function and Inhibition of Beta-Lactamases Brian K. Shoichet, PhD Department of Pharmaceutical Chemistry
International Collaboration in Chemistry: the Chemical Basis for Allosteric Regulation of G Protein Coupled Receptors Brian K. Shoichet, PhD Department of Pharmaceutical Chemistry
Approaches to Discover and Quantify Apoptotic Biomarkers for Cancer Treatment James Wells, PhD Department of Pharmaceutical Chemistry
Development of Small Molecule Inhibitors of the AAA ATPase P97 Michelle Arkin, PhD Department of Pharmaceutical Chemistry
Chemical Biology Consortium Michelle Arkin, PhD Department of Pharmaceutical Chemistry
Development of Potent/Selective Lipoxygenase Therapeutics against Stroke Injury Matthew Jacobson, PhD Department of Pharmaceutical Chemistry
Mechanism, Specificity, and Inhibition of Cytochrome P450 Paul R. Ortiz De Montellano, PhD Department of Pharmaceutical Chemistry
Recombinant Antibody Network James Wells, PhD Department of Pharmaceutical Chemistry
Modeling Ion Channel Conductance Michael R Wilson, MD Department of Pharmaceutical Chemistry