Nanoporous Capsules for the Investigation of Macroencapsulation Parameters
Location(s): United States
Our second year of funding was devoted to integrating the improved membrane design with the optimized cell clusters and monitoring of in vitro transport of insulin/glucose/IgG and cell oxygenation. We also focused on creating a macroencapsulation device that allows for recharging of cells. We began evaluations of islet performance within the advanced implant by simulating cyclical changes in blood glucose levels with a sensitive in vitro perifusion system. Finally, we published two papers, one book chapter, three abstracts, gave one presentation, and submitted one article for publication still awaiting acceptance.