The Epigentic Effects Of Arsenic Exposure On Urothelial Cells Of Healthy Bangladeshi Children: A Feasibility Study

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Investigator: Amanda Keller, MS
Sponsor: Global Health Sciences Education

Location(s): Bangladesh

Description

Worldwide, over 100 million people are exposed to potentially carcinogenic levels of arsenic. Bangladesh is home to the largest natural mass poisoning due to arsenic-contaminated drinking water, where one in five deaths can be attributed to chronic arsenic exposure of more than 10 µg/L. Thus far, research has focused on understanding the epigenetic impact of arsenic in healthy and diseased adults as well as diseased children; however, the effects of arsenic exposure in healthy children, defined as children who have had constant high arsenic exposure in utero and early life but have yet to develop a disease, remains unclear. 

MentorsCraig Steinmaus, MD, MPH