Development of Targeted Anti-Cancer Platinum Analogs

Investigator: Kathleen M. Giacomini, PhD
Sponsor: UC Proof of Concept Program

Location(s): United States


With collaborators at MIT, we have characterized a novel platinum compound and determined its interaction with influx transporters as delivery systems. Other platinum compounds are being studied including picoplatin and satraplatin. Studies in mice with xenografts are ongoing to test novel platinum complexes in treating various tumors.