Drug and Diagnostics Development

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Active Projects: 164

Project Investigator All Topics Start date End date
Generation of therapeutic antibodies for serotype F botulism (Continuation of A120963 from NIH G Pool to Subaccount) Immunology
HIV-Specific T-Cell Responses in Rectal Mucosa Peter Hunt, MD Immunology
Naturally acquired immunity to norovirus in a newborn cohort in Peru Caryn Bern, MD, MPH Infectious Disease, Immunology, Newborn and Infant Health
Host-Directed Strategies to Create Synergistic Antibacterial Therapies Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development, Immunology
Phase III Quinolone Meta-Analysis Rada Savic, PhD Drug and Diagnostics Development
Mechanisms of nanostructure-enhanced transepithelial drug delivery Tejal Desai, PhD Drug and Diagnostics Development
A Multi-Centric Evaluation of a Device for Automated Malaria Microscopy (EasyScan Go) Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Detection of C. trachomatis on eye swabs Julius Schachter, PhD Eye Disease and Blindness, Drug and Diagnostics Development
Population genetic analysis and regional variation Kicheol Kim, PhD Genetics
Accurate and unbiased single cell sequencing with digital droplet MDA Adam Abate, PhD Genetics
The Ethics of Inclusion: Diversity in Precision Medicine Research Janet K. Shim, PhD Genetics
1/3 Multidimensional investigation of the etiology of autism spectrum disorder Genetics, Neurology and Mental Health
Trefoil Factor Proteins Modulate Host Immunity against Hookworms Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Physical and Genetic Interaction Landscape of the Tyrosine Kinome Nevan Krogan, PhD, MSc Cancer/Oncology, Diabetes, Immunology
Real-Time Detection of Bloodborne Pathogens by Unbiased Nanopore Sequencing 20150506 Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Novel methods for monitoring long-term drug exposure and resistance amplification during treatment of multidrug resistant tuberculosis John Metcalfe, MD Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development
Combination immune checkpoint blocker inhibition to eliminate HIV latency Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Functional Manipulation of Memory Regulatory T cells in Skin Cancer/Oncology, Immunology
Host Genetics of HIV: Enhancing Discovery through Study Design and New Tools Ruth Greenblatt, MD HIV/AIDS, Genetics
Pharmacogenomics of Bronchodilator Response in Minority Children with Asthma Esteban Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pharmacology and Drug Treatment, Pediatrics
Microfluidic immunoprofiling for biomarker discovery in rheumatoid arthritis Adam Abate, PhD Immunology
Exhaled Breath Biomarkers for the Diagnosis of TB in Children Devan Jaganath, MD Tuberculosis, Drug and Diagnostics Development
HPTN 082 - Protocol Implementation Funding Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development
An implantable hemodialyzer for treatment of End-Stage Renal Disease Shuvo Roy, PhD Drug and Diagnostics Development
Multi-Institutional Randomized Controlled Trial Evaluating Use of Arista Absorbable Surgical Hemostatic Powder Rahul Seth, MD Surgery and Anesthesia, Drug and Diagnostics Development
Microbial Pathogenesis and Host Defense Joanne Engel, MD, PhD Immunology, Residencies, Fellowships, and Postdoctoral Training
High Throughput Screening of Philippine Terrestrial and Marine Organisms for Antimalarial Properties and Identification of Novel Drug Targets Joseph Derisi, PhD Malaria, Drug and Diagnostics Development
A Pharmacogenomics Study of HIV Latency: The Role of Anti-Programmed Cell Death-1 (PD-1) Signaling Sulggi Lee, MD HIV/AIDS, Immunology
Richer Models of Asthma Risk: Bridging the Environment-Genetics Divide Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics
Role of Antigen-Specific T Cell Responses in the Control of TB Joel D. Ernst, MD Tuberculosis, Immunology
Macular Edema Treatment Trials Associated with MUST (META-MUST) Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect Jeffrey Martin, MD, MPH HIV/AIDS, Cancer/Oncology, Drug and Diagnostics Development
Image-Based Numerical Predictions of Hemodynamics following Vascular Intervention David Saloner, PhD Cardiovascular Disease, Drug and Diagnostics Development, Neurology and Mental Health
Novel Linkers for Antibody-Drug Conjugates Adam Renslo, PhD Immunology
Investigating ASPM regulation of asymmetric division for therapeutic opportunities Genetics
Validation of the GeneXpert Breast Cancer STRAT4 Assay for Rapid Analysis of Breast Cancer Biomarker Status from Fine Needle Aspiration Biopsies in Tanzania (GX-BCB Dianna Ng, MD Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Reducing Breast Cancer Risk in Korean American Women Janice Tsoh, PhD Cancer/Oncology, Genetics, Immigration and Migration
Integrative Program in Complex Biological System (ipCBS) Joseph Derisi, PhD Drug and Diagnostics Development, Immunology, Genetics, Residencies, Fellowships, and Postdoctoral Training
Investigating Mechanisms of HIV Persistence in the Gut Peter Hunt, MD HIV/AIDS, Immunology
Effect of IL-1B inhibition on inflammation and cardiovascular risk in HIV HIV/AIDS, Immunology
Targeting latent HIV-1 Reservoirs with the Antibody-Drug Conjugate, Brentuximab Vedotin HIV/AIDS, Immunology
Alcohol's impact on immunological and virological profiles in HIV patients Mandana Khalili, MD HIV/AIDS, Immunology, Substance Abuse
Interventions to Improve Non-Malarial Fever Diagnosis in Mobile Health Clinics in Mulanje, Malawi Fiona Sylvies, BS Infectious Disease, Drug and Diagnostics Development
Selective AAK1 and GAK inhibitors for combating Dengue and other emerging viral infections Raul Andino-Pavlovsky, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Aqueous-PREP: A Pragmatic Randomized trial Evaluating Pre-operative aqueous antiseptic skin solutions in open fractures Saam Morshed, MD, MPH, PhD Surgery and Anesthesia, Drug and Diagnostics Development
Development, Assessment And Validity Comparison Of Approaches To Eliciting Patient Preferences Across Risk Groups: A Case Study On Innovative Preference Sensitive Treatments (Type 1 Diabetes Or Hereditary Retinal Dystrophy Or Osteoarthritis) Leslie Wilson, PhD, MS Diabetes, Genetics
Pilot Testing, Refinement, and Validation of the Infrastructure to Develop -RADS-based Registries Marc Kohli, MD Cancer/Oncology, Drug and Diagnostics Development
Validation of Existing Ultra-Sensitive Assays for Quantifying HIV Persistence Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Simcere Surpi eval project Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
UZ-UCSF Clinical Trials Unit Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health, Family Planning, Pediatrics, Newborn and Infant Health
Novel Therapeutics for Treatment of River Blindness and Lymphatic Filariasis Judy Sakanari, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Funding-NSW-QB3 Rosenman Institute Scholarship Program Regis Kelly, MD Drug and Diagnostics Development, Residencies, Fellowships, and Postdoctoral Training
New York Center for Collaborative Research in Common Disease Genomics Esteban Burchard, MD, MPH Genetics
Improving urine-based tuberculosis diagnosis in people living with HIV​ Devan Jaganath, MD Tuberculosis, Drug and Diagnostics Development
Improving the efficiency of clinic-based active tuberculosis case finding: point-of-care C-reactive protein-based TB triage testing in Vietnam​ Christina Yoon, MD, MPH Tuberculosis, Drug and Diagnostics Development
International Network for Strategic Initiatives in Global HIV Trials (INSIGHT): START Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Evaluation of the performance of rapid, non-sputum based, biomarker-based test for tuberculosis (TB) diagnosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
MicroRNAs Circulantes Asociados Con Riesgo De Diabetes En Latinos Elena R. Flowers, PhD, RN Diabetes, Drug and Diagnostics Development
A Collaborative Approach to the Design of a Genetically-Stable Oral Polio Vaccine (OPV-2) Raul Andino-Pavlovsky, PhD Infectious Disease, Drug and Diagnostics Development
Craniofacial defects in the manta-ray line. A novel model for ribosomopathies Oral Health, Genetics
Measuring the Latent reservoir for HIV Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Cellular and Bacterial Dynamics in Tuberculosis Joel D. Ernst, MD Tuberculosis, Immunology
Developing an breast FNA biopsy service in Trujillo Peru Ronald Balassanian, MD Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Polyclonal Tregs to Promote Tolerance in Pediatric Liver Transplant Recipients Surgery and Anesthesia, Immunology
TB Surrogate Markers for Assessing Response to Treatment (TB SMART Study) Payam Nahid, MD, MPH Tuberculosis, Drug and Diagnostics Development
Regulation of Innate Immune Signaling by Lyn Kinase Immunology
Macular Edema Treatment Trials Associated with MUST (META-MUST) Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development
Regulation of cardiovascular transcription Cardiovascular Disease, Genetics
GS-US-382-3961: A Phase 1b, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of GS-9620 in Antiretroviral Treated HIV-1 Infected Controllers Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Timing of ART and homeostasis of the persistent HIV reservoir in the adult Mike McCune, MD, PhD HIV/AIDS, Immunology
Microfluidic PCR Method to Identify and Characterize HIV-Infected Single Cells HIV/AIDS, Drug and Diagnostics Development
Impact of Cannabis on Inflammation and Viral Persistence in Treated HIV/SIV Peter Hunt, MD HIV/AIDS, Immunology
A Technological Platform for the Identification of Serine Proteases in Cancer Charles Craik, PhD Cancer/Oncology, Drug and Diagnostics Development
Immunologic determinants of age-related macular degeneration Peter Hunt, MD Eye Disease and Blindness, Immunology, Aging
A smartphone-based point-of-care test for detection of Chlamydia trachomatis Julius Schachter, PhD Sexually Transmitted Infections (STIs), Drug and Diagnostics Development
Center for Multi- and Trans-ethnic Mapping of Mendelian and Complex Diseases Esteban Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pediatrics
Programming Long Term Durable HIV-1 Specific T cell Responses Steven Deeks, MD HIV/AIDS, Immunology
Targeting BET-bromodomains in neuroblastoma Cancer/Oncology, Drug and Diagnostics Development, Pediatrics
Identification of Cobra-specific antibodies Charles Craik, PhD Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Pharmacokinetics and tolerability of adjunctive linezolid for the treatment of tuberculous meningitis Felicia Chow, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment
The impact of TB co-infection on the reservoir of persistent HIV in vivo Mike McCune, MD, PhD HIV/AIDS, Tuberculosis, Immunology
3/3 Integrative Genomic Analysis of Human Brain Development and Autism Genetics, Neurology and Mental Health
ACC: Callosal Agenesis as a Window into Common Neurodevelopment Disorders Elliott Sherr, MD, PhD Genetics, Neurology and Mental Health, Dementia and Cognitive Impairment
A Web-Based Automatic Virtual Screening System Genetics
Hepatic degradation of cytochrome P450 enzymes Maria Correia, PhD Drug and Diagnostics Development
Impact of Low IL-10 Levels at Birth and Leukemia Risk Cancer/Oncology, Immunology
New therapeutic HPV vaccines for HIV-infected men and women Joel Palefsky, MD Genetics
Developing and adapting innovative diagnostic assays for low-resource settings Dianna Ng, MD Infectious Disease, Drug and Diagnostics Development
Bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples Taylor Sittler, MD Infectious Disease, Drug and Diagnostics Development
A Phase 1b (Open-Label) / Phase 2 (Randomized, Double-Blinded) Study Evaluating Gemcitabine and Docetaxel with or without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma Cancer/Oncology, Drug and Diagnostics Development
Viral metagenomics to discover viruses Eric Delwart, PhD Transfusion Medicine, Drug and Diagnostics Development, Epidemiology and Surveillance
IgA regulation of mucosal biome Keith Mostov, MD, PhD Immunology
Transfusion science and HIV, HTLV, and dengue research in Brazil Philip Norris, MD Infectious Disease, HIV/AIDS, Immunology, Health Systems Strengthening, Risk Reduction and Prevention, Training and Capacity Building
Immunology & epidemiology of intestinal infectious diseases Robert Owen, MD Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Epidemiology and Surveillance
Developing new vaccines for Global Health applications Margaret Liu, MD Drug and Diagnostics Development, Immunology
Chlamydial sexually transmitted diseases and trachoma Deborah Dean, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Eye Disease and Blindness, Drug and Diagnostics Development
Incidence, Prevalence and Risk Factors for Sexually Transmitted Infections in Fiji Deborah Dean, MD, MPH Infectious Disease, Sexually Transmitted Infections (STIs), Drug and Diagnostics Development
Nursing education in malarial settings Kimberly Baltzell, RN, PhD, MS Malaria, Drug and Diagnostics Development, Implementation and Behavioral Science, Engagement in Care, Training and Capacity Building, Training International Scholars and Clinicians, Patient and Peer Education
UCSF- Kenyan radiology residency training William Dillon, MD Drug and Diagnostics Development, Training and Capacity Building, Training International Scholars and Clinicians, Distance learning and mentoring
Optimization of health care expenditures to maximize societal value Dhruv Kazi, MD, MSc, MS Cardiovascular Disease, Drug and Diagnostics Development, Health Economics and Effectiveness
Zika virus infection using models of the human placenta Lenore Pereira, PhD Immunology, Newborn and Infant Health
Antigen export in M. tuberculosis evasion of CD4 T cells Joel D. Ernst, MD Tuberculosis, Immunology
Disease susceptibility and global distribution of genetic variation Mark Seielstad, PhD HIV/AIDS, Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Transfusion Medicine, Genetics, Epidemiology and Surveillance
Screening for kidney disease Michael Shlipak, MD Drug and Diagnostics Development
Biomedical simulation models describing how molecular level events effect changes in phenotype C. Anthony Hunt, PhD Immunology, Genetics
Hedgehog signaling at the cell's antenna: Smoothened and the primary cilium Jeremy Reiter, MD, PhD Genetics
Testing Medicinal Plants from Uganda for HIV Latency Reversing Activity Emmanuel Mande, BSc Drug and Diagnostics Development
A Randomized, Double-Blind, Placebo-Controlled, SingleAscending Dose Study to Assess the Safety, Tolerability,and Pharmacokinetics of C2N-8E12 in Subjects withProgressive Supranuclear Palsy Adam Boxer, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health
Dissecting the effect of paracrine responses to Zika virus on neurodevelopment in the human brain Hanna Retallack, AB Zoonosis, Emerging Disease, and Drug Resistance, Immunology
A Technological Platform for the Identification of Serine Proteases in Cancer Charles Craik, PhD Cancer/Oncology, Drug and Diagnostics Development
Single Cell Characterization of Latent HIV-1 Reservoirs HIV/AIDS, Immunology
Allosteric Regulation in the KDM5 Family of Histone Demethylases Immunology
QB3 Entrepreneurship Programs Regis Kelly, MD Drug and Diagnostics Development
Impact of Chemotherapy and Stem Cell Transplant on HIV-1 Reservoir Dynamics HIV/AIDS, Drug and Diagnostics Development
Interventional Study to Assess the Safety and Efficacy of Pharmaceutical Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Dravet Syndrome Drug and Diagnostics Development, Neurology and Mental Health
Study to Assess the Long-term Safety of Pharmaceutical Cannabidiol Oral Solution as an Adjunctive Treatment for Pediatric and Adult Subjects With a Treatment-resistant Seizure Disorder Who Complete INS011-14-029, INS011-14-024, or INS011-14-25 Drug and Diagnostics Development, Neurology and Mental Health, Pediatrics
INS011-14-029: A Phase 1/2 study to assess the pharmacokinetics and safety of multiple doses of pharmaceutical Cannabidiol Oral Solution in pediatric subjects with treatment-resistant seizure disorders Drug and Diagnostics Development, Neurology and Mental Health, Pediatrics
Host-pathogen interactions: Unveiling common mechanisms for rewiring host factors in infectious processes Nevan Krogan, PhD, MSc Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Genetics
SIngle-saMPLE tuberculosis evaluation to facilitate linkage to care: The SIMPLE TB trial Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
UC Valley Fever Research Initiative Anita Sil, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Genetics
Genes, air pollution, and asthma severity in minority children Esteban Burchard, MD, MPH Chronic Respiratory Disease, Genetics
INTERCEPT: Interfering and Co-evolving Prevention and Therapy Raul Andino-Pavlovsky, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Using Genetics and Genomics to Dissect Coccidioides Spherulation Anita Sil, MD, PhD Genetics
Novel serologic assays of P. falciparum exposure for improved surveillance in control and elimination Bryan Greenhouse, MD Malaria, Drug and Diagnostics Development, Epidemiology and Surveillance
EV71 intra-host evolution, attenuation and vaccine development Raul Andino-Pavlovsky, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Effector and regulatory T cell responses and protection from clinical malaria Margaret Feeney, MD Malaria, Drug and Diagnostics Development, Immunology
Improving the molecular diagnosis of drug resistant tuberculosis Midori Kato-Maeda, MD Tuberculosis, Drug and Diagnostics Development
HIV Cures - Paving the way towards elimination of HIV persistent CD4 T cell in vivo HIV/AIDS, Immunology
DHHS Intracorporeal Ultrafiltration System and Intracorporeal Hemodialysis System Shuvo Roy, PhD Drug and Diagnostics Development
MitraClip China Trial CRD956 Atif N. Qasim, MD Cardiovascular Disease, Drug and Diagnostics Development
An Open Label, Randomized Phase 2 Trial of Prostvac and Ipilimumab as Monotherapy or in Combination for Men with Localized Prostate Cancer Undergoing Radical Prostatectomy Drug and Diagnostics Development
Exploiting Genomic or Nucleomic Information to Understand HIV Latency in Individuals with Substance Use Disorders Ruth Greenblatt, MD HIV/AIDS, Genetics, Substance Abuse
Role of proviral loci in HIV latency Adam Abate, PhD HIV/AIDS, Immunology
Defining the unique properties of the distinct signaling machinery used by the TCR Immunology
Coverage, Price, and Reimbursement for Multigene Tests for Cancer and Related Conditions Kathryn Phillips, PhD Cancer/Oncology, Genetics
Delaney AIDS Research Enterprise to Cure HIV Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
A Combined Pathogen-Host Sequencing Assay for Diagnosis of Lyme and Other Tickborne Infections Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Adapting to a changing environment: How surface contact induces virulence factor production in Pseudomonas aeruginosa Joanne Engel, MD, PhD Genetics
Tel-Me-Box: Validating and testing a novel, low-cost, real-time monitoring device with hair level analysis among adherence-challenged patients Maria Ekstrand, PhD HIV/AIDS, Drug and Diagnostics Development, Treatment Adherence
Precision Targeting of Castration Resistant Prostate Cancer with a Novel Ferrous Iron-Dependent Therapeutic Delivery and Tumor Imaging Strategy Adam Renslo, PhD Cancer/Oncology, Immunology
RAPID-VL: Optimizing HIV Viral Load Monitoring and Outcomes for High-Risk Populations Vivek Jain, MD HIV/AIDS, Drug and Diagnostics Development
Understanding Ciliary Functions in Mammalian Development Jeremy Reiter, MD, PhD Genetics
amfAR Institute for HIV Cure Research Paul Volberding, MD HIV/AIDS, Drug and Diagnostics Development
Long-term Effects of IDU, HIV, HCV and the Impact of HCV Cure on Immune Activation and Liver Fibrosis in Aging Women Phyllis Tien, MD Infectious Disease, HIV/AIDS, Immunology, Women's Health
Development and Testing of New Computational Methods for Ligand Discovery and Mechanism Genetics
Programing Biomolecular Nanodevices For Targeted Immune Cell Recognition and Payload Delivery Drug and Diagnostics Development
Role of Ceramide in Hepatic Stellate Cell Activation and Liver Fibrosis Jennifer Chen, MD Immunology
HPMI: Host Pathogen Mapping Initiative Nevan Krogan, PhD, MSc Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Genetics
Advancing New Methodologies to Measure Patient Preference for Regulatory Approval of Devices Leslie Wilson, PhD, MS Drug and Diagnostics Development
A Phase 3, Placebo-Controlled, Randomized, Double-Blind, Multi- Center Study of LJPC-501 in Patients with Catecholamine-Resistant Hypotension (CRH) Drug and Diagnostics Development
747-303: A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of beticholic Acid in Subjects with Nonalcoholic Steatohepatitis Mandana Khalili, MD Immunology
2/7-Collaborative genomic studies of Tourette Disorder Genetics, Neurology and Mental Health
Mechanisms of Skeletal Stem Cell Dysfunctions in Traumatic Bone Injuries Theodore Miclau, MD Surgery and Anesthesia, Drug and Diagnostics Development
Closing the gap between observational research and randomized trials for prevention of Alzheimer's Disease and dementia Maria Glymour, ScD, MS Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
2/2 - Cell Type and Region-Specific Regulatory Networks in Human Brain Development and Disorders Genetics, Neurology and Mental Health
Options for Delivery of Short-Course Tuberculosis Preventive Therapy: The 3HP Options Trial Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Health Economics and Effectiveness
Clinical trials to improve the treatment of drug-sensitive and MDR-TB Patrick Phillips, PhD, MS, MA Tuberculosis, Immunology, Pharmacology and Drug Treatment
Dissecting gene dysregulation at the maternal-fetal interface in preeclampsia Susan Fisher, PhD Genetics, Labor and Delivery
UCSF-Stanford Pediatric Device Consortium Michael Harrison, MD Drug and Diagnostics Development, Pediatrics
Placental malaria: The role of inflammation at the maternal-fetal interface Stephanie Valderramos, MD, PhD Malaria, Immunology, Labor and Delivery, Newborn and Infant Health
Redefining Tuberculosis Meningitis with Metagenomics and Host Transciptomics Michael Wilson, MD Tuberculosis, Drug and Diagnostics Development
Adalimumab in Juvenile Idiopathic Arthritis-associated Uveitis Trial (ADJUST) Nisha Acharya, MD Eye Disease and Blindness, Immunology
Host genetic predictors of plasma IL-1b levels and pharmacogenomics of in vivo IL-1b blockade during treated HIV disease Sulggi Lee, MD HIV/AIDS, Immunology, Genetics, Aging
Phase 2b, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, & Pharmacokinetics of Orally Administered ALS-008176 Regimens in Adults Hospitalized with Respiratory Syncytial Virus Steven Stoltz, MD Infectious Disease, Drug and Diagnostics Development

Active Projects: 382

Project Investigator All Topics Start date End date
High Throughput Screening of Philippine Terrestrial and Marine Organisms for Antimalarial Properties and Identification of Novel Drug Targets Joseph Derisi, PhD Malaria, Drug and Diagnostics Development
Swaziland Serology Technical Assistance Michelle Hsiang, MD Malaria, Drug and Diagnostics Development
Sensitivity of Electronic Alcohol Diagnosis Constance Weisner, DrPH Drug and Diagnostics Development
Creating Polyketide Antibiotic Diversity by Engineering Cytochrome P450 Enzymes / UC Discovery Immunology
Vaccine to Prevent HIV Infection in Pregnancy and Newborns Raul Andino-Pavlovsky, PhD HIV/AIDS, Drug and Diagnostics Development, Newborn and Infant Health
UCSF Comprehensive Center for Immunologic Diseases (CCID) Jeffrey Bluestone, PhD Immunology
Novel Tetracyclines as Antimalarial Agents Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Use of r-hGh to Enhance Thymopoiesis and to Facilitate Immune Restoration in Individuals Infected with HIV-1 Mike McCune, MD, PhD HIV/AIDS, Immunology
Effects of Viral Escape on Memory T-Cell Muturation Eric Delwart, PhD Immunology
Phase II Double Blinded, Placebo-Controlled, Efficacy and Safety Evaluation of Allergen Immunotherapy Co-Administered with Omalizumab, an Anti-IgE mAb Jeffrey Bluestone, PhD Immunology
Cohort Study of Patients Receiving Long-Term Combination Therapy [II] Jeffrey Martin, MD, MPH HIV/AIDS, Drug and Diagnostics Development
Population Genetics of the PO1 Locus of SIV and HIV-1 Eric Delwart, PhD HIV/AIDS, Transfusion Medicine, Genetics, Epidemiology and Surveillance
Regulation of Human Thymic Function in Vivo Mike McCune, MD, PhD Immunology
Examination of genome instability in Plasmodium Falciparum using functional genomics Malaria, Genetics
Novel Tetracyclines as Antimalarial Agents Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
High Throughput Assay for Screening Compounds Against T. Brucei Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Development and Testing of New Medications for the Treatment of Emerging Infectious Diseases [I] Philip J. Rosenthal, MD Infectious Disease, Drug and Diagnostics Development
Optimization of Cysteine Protease Inhibitors Targeting Trypanosoma Brucei Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Systematic Review Series on "Antibody and Antigen Detection for the Immunodiagnosis of Tuberculosis" Philip Hopewell, MD Tuberculosis, Immunology, Systematic Reviews and Guideline Development
T Regulatory Cells and T Cell Activation in HIV Disease Steven Deeks, MD HIV/AIDS, Immunology
3D-FSE-zeta equipment William Dillon, MD Drug and Diagnostics Development
HIV Controllers: A Potential Model for HIV Eradication Steven Deeks, MD HIV/AIDS, Immunology
Structural Biology and Targeted Drug Design for AIDS HIV/AIDS, Drug and Diagnostics Development
Herpesviral Gene Expression in Kaposi's Sarcoma HIV/AIDS, Cancer/Oncology, Genetics
Selective Destruction of Cytochrome P450 by Drugs Drug and Diagnostics Development
HIV Vaccine Trials Network - Laboratory Personnel Support Immunology
Double-Stranded RNA Virus in Giardia Genetics
Valganciclovir to Reduce T Cell Activation in HIV Infection Peter Hunt, MD HIV/AIDS, Drug and Diagnostics Development, Immunology
Novel Anti-Malarials by Combinatorial Pharmacogenomics Joseph Derisi, PhD Infectious Disease, Malaria, Drug and Diagnostics Development
Utility of Rapid Diagnostic Tests for Malaria Heidi A. Hopkins, PhD Malaria, Drug and Diagnostics Development, Pediatrics
Elite Controllers Steven Deeks, MD HIV/AIDS, Immunology, Genetics
UCSF-FIND Uganda Project Laurence Huang, MD Tuberculosis, Drug and Diagnostics Development
Host Protein Degradation by Schistosome Parasites Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Phase 2, Multi-Center, Randomized, Double-Blinded, Placebo-Controlled Study to Assess Safety and Immunogenicity of Two Doses of 3?-aminomethylnicotine-P. aeruginosa r Exoprotein A Conjugate Vaccine (NicVAX?) in 2 Different Dosing Schedules in Smokers Drug and Diagnostics Development, Smoking and Tobacco
CORE B: Intracellular Pathogens and Innate Immunity Joseph Derisi, PhD Tuberculosis, Immunology
Probing Below the Surface: Development of a Molecular Diagnostic Assay to Detect Emergent Viral Escape Variants HIV/AIDS, Drug and Diagnostics Development
Development of Falcipain Inhibitors as Antimalarial Drugs Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Examination of the Protective Effect of Pet Ownership on Asthma Development Through Bacterial Community Analysis of Household Dust and Infant Stool Occupational and Environmental Disease, Immunology
Deferasirox (Exjade)-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) Opportunistic Infection, Drug and Diagnostics Development
Sputum Processing Methods Tuberculosis, Drug and Diagnostics Development
Project 2: Effect of Humanized Anti Pcrv Antibody on Total Bacterial Community Composition of Adult Patients with Ventilator-Associated Pneumonia Immunology
Metagenomics for Detection and Discovery of Viruses Associated with Acute Gastroenteritis in Mexico Charles Chiu, MD, PhD Drug and Diagnostics Development
Ultra-Low Viral Detection Using the Abbott RealTime HIV-1 Assay HIV/AIDS, Drug and Diagnostics Development
Subcontract Work in Association with LLNL LDRD Project: COMP-08ERD036 Raul Andino-Pavlovsky, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Chemoprophylaxis and HIV-Host Interactions [II] HIV/AIDS, Immunology
Transcriptional Responses of Parasite and Host during Intestinal Colonization and Invasion by Entamoeba histolytica Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Valley Fever Vaccine Project George Rutherford, MD Zoonosis, Emerging Disease, and Drug Resistance, Opportunistic Infection, Occupational and Environmental Disease, Drug and Diagnostics Development
Develop Clinical Evidence of Substantial Equivalence to Predicate Devices Suellen Miller, PhD, CNM, MHA Drug and Diagnostics Development
Admixture Mapping Development and Testing in African American SLE Genetics
Immunogenetic Studies of Autoimmune Disease Immunology
EBV BMRF-2 Protein in Infection of Oral Epithelial Cells Sharof Tugizov, PhD Noncommunicable and/or Chronic Disease, Drug and Diagnostics Development
Immunological Targeting of APOBEC Proteins to Cure HIV Infection HIV/AIDS, Immunology
Molecular Engineering of Erythrotropic Bacteria for Treatment and Prevention of Human Malaria Joseph Derisi, PhD Malaria, Drug and Diagnostics Development
Targeting Cysteine Proteases--Antiparasitic Chemotherapy Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Microbicide Pregnancy Registry--Microbicide Trials Network Juan Vargas, MD Sexually Transmitted Infections (STIs), HIV/AIDS, Drug and Diagnostics Development, Women's Health, Family Planning
Clinical Pharmacology, Drug Action and Pharmacogenetics Neal Benowitz, MD Drug and Diagnostics Development, Pharmacology and Drug Treatment
Rhbmp2 vs. AutograpH for Critical Size Tibial Defects: a Multi-Center Randomized Trial Amir Matityahu, MD Surgery and Anesthesia, Drug and Diagnostics Development
Case-Control Association Studies and Genetic Confounding Esteban Burchard, MD, MPH Genetics, Risk Reduction and Prevention
Interferon-Gamma Release Assays for the Diagnosis of Tuberculosis in Adults Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Raltegravir Intensification in Antiretroviral-Treated Patients Exhibiting a Suboptimal CD4+T Cell Response Steven Deeks, MD HIV/AIDS, Immunology
Tuberculosis Trials Consortium (TBTC) Payam Nahid, MD, MPH Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Novel Strategies for defining the Role of HLA in SLE Noncommunicable and/or Chronic Disease, Genetics
Identification of Viruses in an Asthma Cohort Charles Chiu, MD, PhD Chronic Respiratory Disease, Drug and Diagnostics Development
Testing novel adjuvants to enhance mucosal immunity elicited by inactivated poliovirus vaccine (IPV) Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development, Immunology
HIV Incidence Testing in Hair Christopher Pilcher, MD HIV/AIDS, Drug and Diagnostics Development, Treatment Adherence
Population Genetic Mapping of Tourette Syndrome Genetics, Neurology and Mental Health
Innate Effector Function and HIV-1 Control Steven Deeks, MD HIV/AIDS, Immunology
Core B: Intracellular Pathogens and Innate Immunity Joseph Derisi, PhD Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Metagenomics for Identification of Infectious Triggers of KLS Charles Chiu, MD, PhD Drug and Diagnostics Development
International Network for Strategic Initiatives in Global HIV Trials/ ICR INSIGHT Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Genetics of Schizophrenia in Oceanic Palau William Byerley, MD Genetics, Neurology and Mental Health, Pediatrics
Inflammatory and Clinical Consequences of Low-Level Viremia in HIV-1 Infected Patients HIV/AIDS, Immunology
Valley Fever Vaccine Project 2010 George Rutherford, MD Zoonosis, Emerging Disease, and Drug Resistance, Opportunistic Infection, Occupational and Environmental Disease, Drug and Diagnostics Development
HIV Entry Inhibitors: A New Therapeutic Option Steven Deeks, MD HIV/AIDS, Immunology
Viruses in Breast Fluid: Biomarkers for Breast Cancer? Kimberly Baltzell, RN, PhD, MS Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Virus Detection Using Microarrays and Characterization of a Novel Cardiovirus Charles Chiu, MD, PhD Drug and Diagnostics Development
CNS Immune / Inflammatory Biomarkers in HIV Controllers Richard Price, MD HIV/AIDS, Immunology
UCSF/Ragon Collaboration on HIV "Elite" Controllers Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development, Immunology, Genetics
Effectiveness of QuantiFERON-TB Gold (QFT-G) in Contact Tracing Elizabeth Fair, PhD, MPH Tuberculosis, Drug and Diagnostics Development
Janssen/Sakanari - flubendazole study 20150930 Judy Sakanari, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Siglec-F and Resolution of Allergic Inflammation Homer Boushey, MD Immunology, Genetics
Diagnostic Imaging Core Laboratory Services: Ischemic Stroke Neuroflow Study, Vasospasm Subjects William Dillon, MD Drug and Diagnostics Development
Replication fidelity mutants as attenuated poliovirus seeds for IPV production Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development, Pharmacology and Drug Treatment
Pfizer International Growth Study (KIGS) - Protocol TRN 87-052-45 (CCID A6281276) Drug and Diagnostics Development
Pharmacogenomics of Antimalarial Drugs Sunil Parikh, MD, MPH Malaria, Genetics, Pharmacology and Drug Treatment
Dissecting the HLA Contribution to Rheumatoid Arthritis Genetics
Bipolar Endophenotypes in Population Isolates Genetics, Neurology and Mental Health
Dissecting the HLA contribution to Rheumatoid Arthritis Genetics
Solitaire With the Intention For Thrombectomy (SWIFT) Study William Dillon, MD Drug and Diagnostics Development
Trypanosome Drug Development Consortium Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Treating HIV-Infected Elite Controllers as a Model of HIV Remission HIV/AIDS, Immunology
Iron-Dependent Drug Delivery as a New Paradigm in Anti-Parasitic Chemotherapy and Prophylaxis Adam Renslo, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Microbicide Pregnancy Registry-Microbicide Trials Network Juan Vargas, MD Sexually Transmitted Infections (STIs), HIV/AIDS, Drug and Diagnostics Development, Women's Health
Secretion of Virulence Factors by Mycobacterium tuberculosis Infectious Disease, HIV/AIDS, Tuberculosis, Genetics
Neurosteroids in Health and Disease Genetics, Neurology and Mental Health
Origami Female Condom User-Preference (FUP) Study Drug and Diagnostics Development, Women's Health, Family Planning
Point-of-Care Diagnostics for STI and UTI Julius Schachter, PhD Drug and Diagnostics Development
Trial of T.cruzi DNA Vaccine in Experimental Model of Disease Challenge Infection Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Viral Discovery in Human and Animal Samples Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Epigenetic Profiling of Multiple Cell and Tissue Types in Sjögren's Syndrome Genetics
RNAi as an Intercellular Antiviral Defense Mechanism Raul Andino-Pavlovsky, PhD Infectious Disease, Genetics
Neuroform Angiographic Analysis (Subset of MAPS study data) Cardiovascular Disease, Drug and Diagnostics Development
RNA Interference and High-Content Image Analysis to Discover New Drug Targets to Treat the Tropical Disease Schistosomiasis Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Identification of the CD8+ Cell Anti-HIV Factor (CAF) HIV/AIDS, Immunology
Identification of Novel Therapeutics Molecules against Old and New World Cutaneous Leishmaniasis Adam Renslo, PhD Drug and Diagnostics Development
A New Field Assay to Diagnose and Monitor Schistosomiasis Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
International Fellowship Program in Drug Development Drug and Diagnostics Development, Training and Capacity Building, Residencies, Fellowships, and Postdoctoral Training
DSC09r-178688 GEH Novel MR Technology (7T & C13) Drug and Diagnostics Development
Evaluation of a Novel Automated PCR Method for Infectious Disease Diagnostics Drug and Diagnostics Development
Characterizing the Role of Immune Activation in HIV Persistence Steven Deeks, MD HIV/AIDS, Immunology
A Specific Mechanism for Non-Specific Inhibition Drug and Diagnostics Development
Identifying Intermediate Phenotypes for Compulsive Hoarding Carol Mathews, MD Genetics, Neurology and Mental Health
Translation Regulation in Giardia lamblia Infectious Disease, Genetics
Pivotal Study of the Apnex Medical Hypoglossal Nerve Stimulation (HGNS) System to Treat Obstructive Sleep Apnea Drug and Diagnostics Development
Task Order Agreement No. CRB-DCR01-S-09-00325 Diane Havlir, MD Drug and Diagnostics Development
Mesalamine to Reduce T Cell Activation in HIV Infection Peter Hunt, MD HIV/AIDS, Drug and Diagnostics Development
Escaneo genomico completo del paciente con diabetes tipo 2 para la busqueda de nuevos marcadores de asociacion con enfermedad Esteban Burchard, MD, MPH Diabetes, Genetics
HLA-A Low Resolution Typing Surgery and Anesthesia, Immunology
Oral Wash for Nucleic Acid Diagnosis and Prognosis of TB in HIV-infected Ugandans HIV/AIDS, Tuberculosis, Drug and Diagnostics Development
Initiation of Allergic Immunity by Parasites Richard Locksley, MD Immunology
Development of Human mAbs to Target Cardiomyocytes and Cardiac Fibroblasts Cardiovascular Disease, Immunology
A Rapid Pan-Viral Microarray Diagnostic for Category A-C Biodefense Pathogens Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Philips Mra Research Plan B-9 (Dose Aware) Saam Morshed, MD, MPH, PhD Surgery and Anesthesia, Drug and Diagnostics Development
Whole Genome Sequencing of Multiplex Schizophrenia Pedigrees from an Isolated Population William Byerley, MD Genetics, Neurology and Mental Health
Wave 80 Fingerstick Pilot Study Christopher Pilcher, MD Drug and Diagnostics Development
Early Diagnosis of Human Prion Disease Michael Geschwind, MD, PhD Infectious Disease, Drug and Diagnostics Development
Phase 1 Iontophoretic Delivery of Dexamethasone for Tx of Anterior Scleritis Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Development of Targeted Anti-Cancer Platinum Analogs Cancer/Oncology, Drug and Diagnostics Development
K777 for the Treatment of Chagas' Disease, IND-enabling Studies and IND Submission Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Early Detection of Metastasis-Prone Breast Cancers Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Novel Technologies to Increase the Accessibility and Accuracy of Tuberculosis Diagnostic Services in Hanoi Province, Vietnam Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Nanostructured Polymer Films and Microneedles Tejal Desai, PhD Drug and Diagnostics Development
Microbicide Pregnancy Registry--Microbicide Trials Network Juan Vargas, MD Sexually Transmitted Infections (STIs), Drug and Diagnostics Development, Women's Health, Family Planning
Novel Maltodextrin-Based, Bacterial Targeting Probes for Bioimaging of Viable MTB in Vivo Payam Nahid, MD, MPH Tuberculosis, Drug and Diagnostics Development
Microfluid Chip Design Adam Abate, PhD Drug and Diagnostics Development
An Open-Label, Multicenter Study Evaluating the Safety and Tolerability of Once-Daily Oral Aripiprazole in Children and Adolescents with Tourette's Disorder Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health
Sanofi-Aventis SAR650894 Program - Research Component Cancer/Oncology, Drug and Diagnostics Development
Nanoengineered Thin Film Devices for Ocular Drug Delivery Tejal Desai, PhD Drug and Diagnostics Development
Nanoporous Capsules for the Investigation of Macroencapsulation Parameters Tejal Desai, PhD Diabetes, Drug and Diagnostics Development
Childhood Arthritis and Rheumatology Research Alliance Registry (CARRA Registry): Lupus Nephritis Consensus Treatment Plan Maintenance Phase Immunology
Whole Genome Analyses for Asthma in Latino Populations Esteban Burchard, MD, MPH Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics
Public Health Research, Epidemiology, and Surveillance for Hemoglobinopathies (PHRESH) Sickle Cell Disease (SCD)/ Thalassemia Case Reporting James Huang, MD Infectious Disease, Genetics, Health Systems Strengthening, Risk Reduction and Prevention
Genetic Diversity as a Determinant of Viral Pathogenesis and Attenuation Raul Andino-Pavlovsky, PhD Infectious Disease, Genetics, Risk Reduction and Prevention
Lysosomal Storage Disorders Genetic Counselor Fellowship (Genzyme 43737) Noncommunicable and/or Chronic Disease, Genetics, Pediatrics
Diagnostic Antibody for Type A Botulism Infectious Disease, Drug and Diagnostics Development
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach Nevan Krogan, PhD, MSc Noncommunicable and/or Chronic Disease, Cancer/Oncology, Genetics
Broad Spectrum Antivirals Targeting Envelope Proteolysis and Viral Uncoating Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Chemicals with Potential Activity against Malaria Parasites Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Bioresponsive Scaffold Designed to Promote Bone Regeneration Through a Cartilage Intermediate Drug and Diagnostics Development
A User-Friendly Epidemic-Economic Model of Diagnostic Tests for Tuberculosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Epidemiology and Surveillance
Fellowship in Clinical Biochemical Genetics Genetics, Residencies, Fellowships, and Postdoctoral Training
Effects of CCR5 - delta-32 Heterozygosity on the HIV-1 Reservoir Steven Deeks, MD HIV/AIDS, Immunology, Genetics
Comprehensive Diagnostics for Viral Encephalitis/Meningitis Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Lead Identification to Clinical Candidate Selection: Drugs for Chagas' Disease Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
DNA methylation profiling in Rheumatoid Arthritis Immunology
Comprehensive Assay Platform and Database for Drug Transporter Interaction Studies Drug and Diagnostics Development
Collaborative Molecular Genetic Investigation of Pediatric Myelodysplatic Syndromes Genetics, Neurology and Mental Health
Identification and Validation of Targets of Phenotypic High Throughput Screening Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Global Innate Immune Responses to HIV-1 Infection Nevan Krogan, PhD, MSc HIV/AIDS, Immunology
Epi4K: Gene discovery in 4,000 Epilepsy Genomes (4/7) Elliott Sherr, MD, PhD Cardiovascular Disease, Genetics
Multiplexed Viral and Cytokine Response Assays Using NanoString Technology Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Pathogen Discovery in PREDICT Human and Wildlife samples to Detect and Identify Viruses Present, Both Known and Novel Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Health Professional Research Preceptorship Immunology
Nanoscale Science and Engineering Center (NSEC) Tejal Desai, PhD Drug and Diagnostics Development
Development of Regulatory T-Cells for Treatment of Autoimmune Disease Jeffrey Bluestone, PhD Immunology, Pharmacology and Drug Treatment
Stem Cell differentiation to thymic epithelium for inducing immune tolerance to stem cells Immunology
Donation of Primaquine for the UCSF-Sponsored Phase 2A Dose Escalation Study of the Efficacy, Safety and Pharmacokinetics of Low Single-Dose Primaquine for Gametocytocidal Activity against P. Falciparum in Sub-Saharan Africa Roland Gosling, PhD, MS, MD Malaria, Drug and Diagnostics Development
Structure and Engineering of Natural Product Cytochrome P450 Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Parirenyatwa - International Maternal Pediatric Adolescent AIDS Clinical Trials Group UZ UCSF CTU Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
Development of Human mABs to CXCR1 and CXCR2 Immunology
High Throughput Measurement of Envelope Gene Diversity for an HIV Incidence Assay Christopher Pilcher, MD HIV/AIDS, Drug and Diagnostics Development
Clin 0003 Identification and Characterization of a Putative Novel Poxvirus in the DRC Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Recent Thymic Emigrants of the CD4 T-Cell Lineage Mike McCune, MD, PhD Immunology
Clin 0004 Characterization of Viral Hemorrhagic Fevers of Unknown Origin Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Whole Genome Sequencing in Multiple Sclerosis Genetics
Performance Evaluation of the Bio-Rad Geenius HIV-1/2 Supplemental Assay Christopher Pilcher, MD HIV/AIDS, Drug and Diagnostics Development
A 6 month Multi-center, Open-label Safety Study of VIMOVO in Adolescents Immunology, Adolescent Health
Immunodiagnosis of Active Tuberculosis in HIV-Infected Patients Adithya Cattamanchi, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development
CHRP Disparities Initiative: UCSF CFAR Conference Award Paul Volberding, MD HIV/AIDS, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Genome-Wide Association Study to Examine Genes Associated with An Increased Risk of Febrile Seizure in Children Following Measles-Containing Vaccines Mark Seielstad, PhD Infectious Disease, Transfusion Medicine, Immunology, Pharmacology and Drug Treatment, Pediatrics, Epidemiology and Surveillance
Deep Sequencing Clinical Analysis Tool for Infectious Disease Infectious Disease, Drug and Diagnostics Development
Collaborative Network for Clinical Research on Immune Tolerance - Offcampus Portion Jeffrey Bluestone, PhD Diabetes, Immunology
Collaborative Network for Clinical Research on Immune Tolerance Jeffrey Bluestone, PhD Diabetes, Immunology
Designing a Sonographic Medium for Low Resource Settings Drug and Diagnostics Development
An Automated High Throughput Phenotypic Screen for Schistosomiasis Drug Discovery Infectious Disease, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Mechanisms of B Cell Responses in Autoimmune Disease: C12-ALE05-CSF Immunology
Preventing Fucose-Dependent Binding of Aspergillus and Pseudomonas to Lung Mucin Infectious Disease, Chronic Respiratory Disease, Genetics
Structure-Aided Design of CYP51 Inhibitors for Treatment of Parasitic Infections Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Gender-specific Differences Affecting Reactivation of Latent HIV in Treated Patients Steven Deeks, MD HIV/AIDS, Immunology, Women's Health
Oncogenic Viral Biomarkers in Nonmalignant Human Breast Tissue Kimberly Baltzell, RN, PhD, MS Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Fusion Genes As Therapeutic Targets in Malignant Pleural Mesothelioma Cancer/Oncology, Drug and Diagnostics Development
Dual Energy X-Ray Absorptiometry (DXA) Scan Analysis and Quality Control Review for NHANES 2011-2016 Drug and Diagnostics Development
An optogenetic method to rapidly and reversibly titrate protein levels in cells Genetics
CCD Study- RNA Sequencing Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
PAAR4Kids-Pharmacogenomics Research Network Cancer/Oncology, Genetics, Pharmacology and Drug Treatment
Preparing for Human Studies Using the Spinlab Polarizer Drug and Diagnostics Development
Mobile Phone Platform for Genomic Disease Detection Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Genetics
Multimodal Imaging of Antibody-Mediated Therapy for Japanese Encephalitis Virus Michael Wilson, MD Infectious Disease, Drug and Diagnostics Development
Barriers to point-of-care G6PD testing for P.vivax malaria in Malaysia: a qualitative study Jessica Jaswal, MS Malaria, Drug and Diagnostics Development, Access or Barriers to Care
Risk of Leukemia after Protracted Exposures to Low Doses of Ionizing Radiation. Lydia Zablotska, MD, MPA, PhD Noncommunicable and/or Chronic Disease, Cancer/Oncology, Genetics, Epidemiology and Surveillance, Risk Reduction and Prevention
Mechansims of poliovirus replication Raul Andino-Pavlovsky, PhD Infectious Disease, Noncommunicable and/or Chronic Disease, Genetics
Cross-Sectional Examination of Cerebrospinal Fluid Kinetic Biomarkers of Axonal Transport for Amyotrophic Lateral Sclerosis (Als) Diagnosis and Progression Richard Price, MD Drug and Diagnostics Development
Nanoporous Films for Ocular Drug Delivery Tejal Desai, PhD Eye Disease and Blindness, Drug and Diagnostics Development
Silicon Dialyzer Prototype Shuvo Roy, PhD Drug and Diagnostics Development
High throughput proteomics to dissect Chlamydia-host cell interactions Joanne Engel, MD, PhD Infectious Disease, Sexually Transmitted Infections (STIs), Genetics, Risk Reduction and Prevention
An Evolutionary-Developmental Approach to Stem Cells Using Teeth As a Model Oral Health, Genetics, Training International Scholars and Clinicians
International Collaboration in Chemistry: the Chemical Basis for Allosteric Regulation of G Protein Coupled Receptors Drug and Diagnostics Development
Alfred P. Sloan Foundation Fellowship Genetics
A Novel Myeloid Subset Mediating Tolerance to Malaria Malaria, Immunology
Establishing a Core Facility for Virus Detection and Discovery Charles Chiu, MD, PhD Drug and Diagnostics Development, Epidemiology and Surveillance
Pathogen characterization and discovery by deep sequencing of two major vectors associated with Lyme disease and other tickborne infections Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Gilead HCAT Support-SOMA Project James Dilley, MD Genetics
Discovery of benzoxaboroles for the treatment of cryptosporidiosis Philip J. Rosenthal, MD Infectious Disease, Drug and Diagnostics Development
Comprehensive Diagnostics for Viral Encephalitis/Meningitis Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Identifying and targeting HIV persistence in T Cell subsets during ART Steven Deeks, MD Drug and Diagnostics Development, Immunology, Genetics
QB3 Entrepreneurship, Train the trainers program Regis Kelly, MD Drug and Diagnostics Development, Training and Capacity Building, Training International Scholars and Clinicians
UZ-UCSF CTU Spilhaus Clinical Research Site HPTN 076 2nd Protocol Funding Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development
Biostatistical analysis of Mycobacterium Tuberculosis Biomarkers for Diagnosis and Cure Rada Savic, PhD Tuberculosis, Drug and Diagnostics Development
Novel Maltodextrin-Based, Bacterial Targeting Probes for Bioimaging of Viable MTB In Vivo Payam Nahid, MD, MPH Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development
Health Professional Research Preceptorship Immunology, Residencies, Fellowships, and Postdoctoral Training
Health Professional Research Preceptorship Immunology, Residencies, Fellowships, and Postdoctoral Training
An Ultrasensitive in Vivo Latent HIV Viral Outgrowth Assay Using Humanized Mice HIV/AIDS, Drug and Diagnostics Development
Risk-Benefit Trade-Offs for Whole Genome Sequencing Kathryn Phillips, PhD Cancer/Oncology, Genetics
Genetic Diversity as a Determinant of Viral Adaptation and Pathogenesis Raul Andino-Pavlovsky, PhD Infectious Disease, Immunology
Genetics of Brazilian Populations Mark Seielstad, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Transfusion Medicine, Genetics, Epidemiology and Surveillance
Mechanism of enterovirus replication Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development
The Role of Continuous Phenotypic Variation in Structural Defects of the Face Genetics, Newborn and Infant Health
UCSF Cutaneous Immunology Core: OSM Project Opportunistic Infection, Cancer/Oncology, Immunology
Streamlined TB Diagnosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Broad Detection of Infectious Agents in Blood by Microarrays and Deep Sequencing Charles Chiu, MD, PhD Infectious Disease, Drug and Diagnostics Development
Schistosome Research Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Mechanisms of B Cell Responses in Autoimmune Disease Oral Health, Immunology
Hologic - Analytical sensitivity comparison of a new molecular assay for Plasmodium detection with a qualitative nested PCR assay and a quantitative PCR assay 20150330 Bryan Greenhouse, MD Malaria, Drug and Diagnostics Development
Biomarkers for Malaria Eradication (BIOME) Bryan Greenhouse, MD Malaria, Drug and Diagnostics Development
Comparative Effectiveness of Rapid Diagnostics for Tuberculosis in Uganda Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Epidemiology and Surveillance
Interferon-independent mechanisms of malaria restriction by helper T cells Mike McCune, MD, PhD HIV/AIDS, Malaria, Immunology
Characterization of Familial Advanced Sleep Phase Syndrome Louis Ptacek, MD Genetics
Medical and Graduate Student Preceptorship - Mok Immunology, Residencies, Fellowships, and Postdoctoral Training
Integrating computation and genetics to quantify specificity in protein networks Nevan Krogan, PhD, MSc Genetics
Large-Scale Production and In-Vivo Characterization of Therapeutic DNA Nanodevices Drug and Diagnostics Development
Whole Blood/Serum Samples from Patients with Hepatitis Charles Chiu, MD, PhD Infectious Disease, Drug and Diagnostics Development
Genetic Determinants of Capecitabine Toxicity Genetics, Pharmacology and Drug Treatment
UCSF/UCB Joint Graduate Group in Bioengineering Tejal Desai, PhD Drug and Diagnostics Development, Residencies, Fellowships, and Postdoctoral Training
Automated smear-positive tuberculosis diagnosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Discovering Drugs for Prion Diseases Drug and Diagnostics Development
Accurate, long-read sequencing with droplet-microfluidic barcoding Adam Abate, PhD Infectious Disease, Cancer/Oncology, Genetics
Exploring the role of a novel, polymorphic protein family in M. tuberculosis pathogenesis Tuberculosis, Immunology
Patient beliefs about the relationship between Chronic Non-Cancer Pain (CNCP) management, alcohol and marijuana use in safety net, primary health care settings Jorge Ramirez, MD, MPH, MS Drug and Diagnostics Development
RAPID: Ebola virus population structure, genetic diversity and evolution Raul Andino-Pavlovsky, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Self-Assembled DNA Devices for Nanoscale Manipulation of Immune Signal Transduction Drug and Diagnostics Development
Trefoil Factors Regulate Th2 Immunity Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Immunology
Mechanism, Specificity, and Inhibition of Cytochrome P450 Drug and Diagnostics Development, UCSF Professional Education
Reactivation of latent HIV using recombinant galectin-9 HIV/AIDS, Immunology
Flexible Resorbable Organic and Nanomaterial Therapeutic Systems (FRONTS) Shuvo Roy, PhD Drug and Diagnostics Development
Molecular and Cellular Mechanisms of Synaptic Growth Genetics
Tissue Biopsy Samples from Head and Neck Cancers Charles Chiu, MD, PhD Cancer/Oncology, Drug and Diagnostics Development
Towards Therapeutics for Neurodegenerative Diseases Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
Genome wide association study of breast cancer subtype and survival in Latinas Laura Fejerman, PhD Cancer/Oncology, Genetics, Epidemiology and Surveillance
Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophages Tuberculosis, Immunology
Treatment of SLE with ajulemic acid,a non-psychoactive cannabinoid derivative Immunology
Biomarkers for PTSD in Female Iraq and Afghanistan Veterans Drug and Diagnostics Development, Trauma and PTSD
Micro- and Nano-Structured Biopolymer Thin Film Devices for Small Molecule Drug Delivery Tejal Desai, PhD Drug and Diagnostics Development
Development of the infant gastrointestinal virome and shedding of oral polio and rotavirus vaccines in Bangladeshi and US infants Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Newborn and Infant Health
Evaluation of Pao Pereira, a natural product of the extract of rainforest tree, in malignant brain tumor cell lines Cancer/Oncology, Drug and Diagnostics Development
Developing a Macrofilaricidal Drug for Onchocerciasis Using Anacor's Novel Oxaborole Technology Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation Jeffrey Bluestone, PhD Immunology
High-Throughput Phenotyping and Continuous Evolution Systems Adam Abate, PhD Drug and Diagnostics Development
LOC-IMPAACT Leadership Group Francesca Aweeka, PharmD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment, Women's Health, Pediatrics, Newborn and Infant Health, Systematic Reviews and Guideline Development
Immunomodulation of transplant rejection by anti-CD3 mAb Jeffrey Bluestone, PhD Immunology
Philippine-UC Collaboratory for Device Innovation (Education/Training Award) Michael Harrison, MD Zoonosis, Emerging Disease, and Drug Resistance, Malaria, Drug and Diagnostics Development, Genetics, Training International Scholars and Clinicians
Quantitative mapping of interactions between dengue virus and its hosts Zoonosis, Emerging Disease, and Drug Resistance, Immunology
The Amyotrophic Lateral Sclerosis (ALS)/Parkinsonism-Dementia Complex of Guam: Exploring the Mechanism of a Rare Tauopathy Michael Geschwind, MD, PhD Genetics, Neurology and Mental Health
Prostate Cancer Therapeutic Clinical Investigation "First in Man" Cancer/Oncology, Drug and Diagnostics Development
Impact of Sirolimus (Rapamycin) on HIV-1 Persistence and Immune Function HIV/AIDS, Drug and Diagnostics Development
Development of Antimalarial Drug Leads Through Inhibition of Food Vacuole Falcipains Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Building an Implantable Artificial Kidney Shuvo Roy, PhD Drug and Diagnostics Development
Trans-Synaptic Signaling during Neuromuscular Development Immunology, Neurology and Mental Health
A Specific Mechanism for Non-Specific Inhibition Immunology
Provider Practices in Non-Malarial Fevers: A Pilot Study in Malawi Kimberly Baltzell, RN, PhD, MS Drug and Diagnostics Development, Pharmacology and Drug Treatment
Enabling New Translational Discoveries Using a Genomic Data-Driven Nosology Atul Butte, MD, PhD Cancer/Oncology, Immunology
Biocompatibility of Implantable Renal Replacement Devices Shuvo Roy, PhD Drug and Diagnostics Development
Mass Spectrometry Tools in Pursuit of Salivary Biomarkers of Sjogren Syndrome Oral Health, Immunology
Extending ASD risk locus discovery to the non-coding genome Genetics, Neurology and Mental Health
HIV-Specific T-Cell Responses in Rectal Mucosa Elizabeth Sinclair, PhD HIV/AIDS, Immunology
Plasmodium Falciparum Infection and Interference with Effective B Cell Memory Bryan Greenhouse, MD Malaria, Immunology, Pediatrics
Creating Maps of 4D Brain Images to Unravel Dementia Heterogeneity of Aging HIV Population Victor Valcour, MD, PhD Drug and Diagnostics Development, Dementia and Cognitive Impairment
A Web-Based Automatic Virtual Screening System Drug and Diagnostics Development
Metabiota - Viral Surveillance for the PREDICT Program 20150410 Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
NP25737 A Phase I Pharmacokinetic and Safety Study of Tocilizumab (TCZ) in Patients Less Than 2 Years Old With Active Systemic Juvenile Idiopathic Arthritis Noncommunicable and/or Chronic Disease, Immunology, Pediatrics
Study for Sample Acquisition for Patients Diagnosed with S. aureus Bacteremia Henry Chambers, MD Infectious Disease, Drug and Diagnostics Development, Epidemiology and Surveillance
Snakebite treatment in Nepal Tommaso Bulfone, MS Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Drug and Diagnostics Development, Dementia and Cognitive Impairment
he Efficacy of Various Antibiotics at Targeting Wolbachia for the Treatment of Lymphatic Filariasis Emma Gunderson, MS Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development, Pharmacology and Drug Treatment
MR Metabolic Imaging of Response to Targeted Therapies in GBM Cancer/Oncology, Drug and Diagnostics Development
Murine Neuroblastoma Models for Preclinical Therapeutics Cancer/Oncology, Drug and Diagnostics Development
Newborn Screening Program for Sickle Cell James Huang, MD Genetics, Newborn and Infant Health
Genetic Disease Laboratory and Genetic Disease Screening Program on Clinical Laboratory Improvement Amendments (CLIA) 15-10151 Genetics
Defining critical events in early HIV infection-effects of alcohol and early ART Mike McCune, MD, PhD HIV/AIDS, Immunology, Substance Abuse
A pilot study of DNA methylation and response to treatment in RA Immunology
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Effectiveness, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, Policy and Standards of Care, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training
Protein homeostasis mechanisms underlying enterovirus replication and evolution Raul Andino-Pavlovsky, PhD Genetics
Targeting Allosteric Sites to Modulate Protein Interactions and Function Charles Craik, PhD Drug and Diagnostics Development
A point of care assay for chlamydia to assure prompt treatment in at risk minorities Julius Schachter, PhD Infectious Disease, Eye Disease and Blindness, Drug and Diagnostics Development
Elucidating the Fundamental Biology of Memory Regulatory T cells in Skin Cancer/Oncology, Immunology
Identification of Signaling Pathways Associated with Lyme Disease Charles Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
UZ-UCSF CTU Spilhaus Clinical Research Site HPTN 076 2nd Protocol Funding Zvavahera Chirenje, MD, FRCOG Infectious Disease, HIV/AIDS, Drug and Diagnostics Development, Women's Health, Training International Scholars and Clinicians, Patient and Peer Education
Sustained Strengthening of Public Health Laboratory, Transfusion Services and Health Care Worker Infection Control Practices for Ebola Virus Disease in Liberia Kayla Enriquez, MD, MPH Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Transfusion Medicine, Drug and Diagnostics Development, Policy and Standards of Care, Systematic Reviews and Guideline Development, Health Systems Strengthening, Training International Scholars and Clinicians
Placental Malaria: The Role of Macrophages in Placental Inflammation - RSDP Valderramos Stephanie Valderramos, MD, PhD Malaria, Immunology
Oxygen Sensors and P450 Monooxygenases in Mycobacertium tuberculosis Tuberculosis, Immunology
Novel approaches to identify host genes required for Chlamydia pathogenesis Joanne Engel, MD, PhD Infectious Disease, Sexually Transmitted Infections (STIs), Drug and Diagnostics Development
Placental Malaria: The Role of Macrophages in Placental Inflammation - RSDP Valderramos Burroughs Wellcome Fund Stephanie Valderramos, MD, PhD Malaria, Immunology
HARC Center: HIV Accessory and Regulatory Complexes Alan Frankel, PhD Zoonosis, Emerging Disease, and Drug Resistance, HIV/AIDS, Immunology
UCSF-GIVI Center for AIDS Research (CFAR) Paul Volberding, MD HIV/AIDS, Tuberculosis, Malaria, Cancer/Oncology, Cardiovascular Disease, Drug and Diagnostics Development, Immunology, Pharmacology and Drug Treatment, Neurology and Mental Health, Trauma and PTSD, Women's Health, Pediatrics, Implementation and Behavioral Science, Training and Capacity Building, Training International Scholars and Clinicians
Optogenetic dissection of the growth and activation network in T cells Immunology
Clinical Trial of the Infuse/Mastergraft Delayed Healing Device with Rigid Internal Fixation in the Treatment of Tibial Delayed Healing ("Tibia Study") Saam Morshed, MD, MPH, PhD Surgery and Anesthesia, Drug and Diagnostics Development
Antimalarial drugs in Ugandan populations Melissa Conrad, PhD HIV/AIDS, Malaria, Drug and Diagnostics Development, Pharmacology and Drug Treatment, Pediatrics
Mother-child genetic contributions to autoimmunity Immunology
Real-Time Unbiased Pathogen Detection in Febrile Illnesses by Nanopore Sequencing Charles Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse Children Esteban Burchard, MD, MPH Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics, Pediatrics
Randomized, Double-Blind, Phase II Trial of Vitamin D Supplementation in Participants with Previously Untreated Metastatic Colorectal Cancer Katherine Van Loon Steitz, MD, MPH Cancer/Oncology, Drug and Diagnostics Development
Sputum Transcriptomic Expression Profiling in Study 31 (STEPS 31) Payam Nahid, MD, MPH Tuberculosis, Drug and Diagnostics Development
IMPAACT Yr 08 P1077 CTU MOU #2 - Parirenyatwa Zvavahera Chirenje, MD, FRCOG Drug and Diagnostics Development, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
IMPAACT Yr 08 P1077 CTU MOU #2 - Seke North Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
Structural Basis of Protease-Activated Receptor Function HIV/AIDS, Drug and Diagnostics Development
Novel Mechanisms of Beta-lactam Resistance in Staph Aureus Henry Chambers, MD Genetics
NSW-QB3 Rosenman Institute Scholarship Program Regis Kelly, MD Drug and Diagnostics Development, Residencies, Fellowships, and Postdoctoral Training
Genetic and molecular pathophysiology of ATS Louis Ptacek, MD Cardiovascular Disease, Genetics
A Novel Microfluidic HIV-1 Co-Culture Assay to Quantify Latent Reservoirs HIV/AIDS, Drug and Diagnostics Development
Improve the Cho Expression of a ScFv Fragment by Optimizing the DNA Sequence of the ingle chain variable fragment ScFv and/or Leader Sequence Drug and Diagnostics Development, Immunology
A Randomized, Double Blinded, Active-Controlled Study of Cb-183,315 in Patients with Clostridium-difficile-Associated Diarrhea Infectious Disease, Drug and Diagnostics Development
ITN029ST WISP-R - Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients Immunology
Antigen Decoding by T cells Immunology
Molecular Methods for Cervical Cancer Screening in HIV+ Women Nancy Hessol, MSPH Cancer/Oncology, Drug and Diagnostics Development, Women's Health
A feasibility study evaluating a reservoir storage system for continuous oxygen delivery in Uganda Melissa Morgan Medvedev, MD, MSc Drug and Diagnostics Development, Newborn and Infant Health
California Precision Medicine Consortium Atul Butte, MD, PhD Drug and Diagnostics Development
Vertical Transmission of Zika Virus: Histopathological Investigations at the Maternal- Fetal Interface Stephanie Valderramos, MD, PhD Infectious Disease, Drug and Diagnostics Development, Immunology
Chemical Methods for Ferrous Iron Dependent Drug Delivery Adam Renslo, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Multicenter Uveitis Steroid Treatment (MUST) Trial Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development
Mechanisms of Neutrophil Activation Immunology
HIV cure with CCR5 negative human IPS hematopoietic stem cells HIV/AIDS, Drug and Diagnostics Development, Immunology
Gilead Sciences Research Scholars Program in Cystic Fibrosis. Oren Rosenberg, MD, PhD Immunology
Initiation of allergic immunity by parasites Richard Locksley, MD Immunology
HINT: HIV Immune Networks Team Modeling Core Nevan Krogan, PhD, MSc HIV/AIDS, Immunology
ACTG A5335s Specialty Lab Diane Havlir, MD Drug and Diagnostics Development, Immunology, Genetics
Life After Pediatric Sepsis Evaluation, LAPSE Drug and Diagnostics Development, Pharmacology and Drug Treatment, Pediatrics
Phase 1 Train of Na-APR-w and Na-GST-1 Hookworm Vaccine in Brazilian Adults Bryan Greenhouse, MD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Malaria Serology evaluation Bryan Greenhouse, MD Malaria, Drug and Diagnostics Development
Pets and the Infant Microbiome: Effect on Immune Maturation and Atopic Asthma Occupational and Environmental Disease, Immunology
Molecular basis of tissue interactions that regulate craniofacial development Genetics
Enhancing Control of HIV by Inhibiting TRAIL Steven Deeks, MD HIV/AIDS, Drug and Diagnostics Development, Immunology
BSL3 upgrading for Live-attenuated poliovirus testing Raul Andino-Pavlovsky, PhD Infectious Disease, Immunology
p24 Antigen and Alternative Markers in Infants, Vietnam Annette Sohn, MD HIV/AIDS, Drug and Diagnostics Development, Newborn and Infant Health
Evolution and Inhibition of Serine Beta-Lactamase Activity Adam Renslo, PhD Opportunistic Infection, Drug and Diagnostics Development
Identifying Human Breast Carcinogens Using Exposomics Laura Fejerman, PhD Occupational and Environmental Disease, Drug and Diagnostics Development
Core Laboratory for Sputum Quality Assurance and Sputum Analysis Noncommunicable and/or Chronic Disease, Chronic Respiratory Disease, Drug and Diagnostics Development
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases Michael Geschwind, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
Intervascular Capsule for Islet Transplantation in Type I Diabetic Patients Shuvo Roy, PhD Diabetes, Drug and Diagnostics Development
Proteomics Analysis of Host-Pathogen Interactions in Histoplasma Anita Sil, MD, PhD Opportunistic Infection, Immunology
Allosteric Inhibition of a Family of Proteolytic Enzymes Charles Craik, PhD Immunology, Pharmacology and Drug Treatment
A Program of Research in Population Cytogenetics Tracey Woodruff, PhD, MPH Occupational and Environmental Disease, Genetics, Newborn and Infant Health
Factors Associated with G6PD Deficiency Testing Adherence Among P. vivax RDT-positive Individuals Living in Southern Lao PDR Resego Bokete, MS Malaria, Drug and Diagnostics Development
Transthyretin-Associated Amyloidoses Outcomes Survey (THAOS) (Survey ID: Fx-R-001) Jeffrey Ralph, MD Genetics, Neurology and Mental Health
Whole Genome Sequence Characterization of Drug Resistant Malarial Strains Sumayya Mohammed, MS Zoonosis, Emerging Disease, and Drug Resistance, Malaria, Genetics
Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence Constance Weisner, DrPH Drug and Diagnostics Development, Substance Abuse
Validation of candidate ASD genes by targeted sequencing with molecular inversion probes Genetics, Neurology and Mental Health
Antigen Specificity of Regulatory T cells in Type 1 diabetes T1D Jeffrey Bluestone, PhD Diabetes, Immunology
2 year joint fellowship program in Clinical Pharmacy with Actelion Francesca Aweeka, PharmD Drug and Diagnostics Development, Pharmacology and Drug Treatment, Residencies, Fellowships, and Postdoctoral Training
Genomic research on the African diaspora Ian Whitmarsh, PhD Genetics
Impact of interferon-alpha inhibition on immune function and viral persistence in HIV disease Steven Deeks, MD HIV/AIDS, Immunology
Testing Targeted Therapy in Philadelphia Chromosome-Like (Ph-Like) All Cancer/Oncology, Drug and Diagnostics Development
HVTN 703/HPTN 081 Protocol Funding (PF) Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health
New ways of treating pancreatic cancer based on reversing K-Ras-mediated stemness Cancer/Oncology, Immunology
Genetic and epigenetic contributions to Sjogrens syndrome Eye Disease and Blindness, Oral Health, Genetics
Risk-Benefit Trade-Offs for Whole Genome Sequencing Kathryn Phillips, PhD Genetics
Natural Bacteriocins as Pre/Pro-Biotics to Promote Oral Health and Prevent Periodontal Disease Yvonne Kapila, DDS, PhD Oral Health, Drug and Diagnostics Development
Career: Massively-Parallel Single-Cell Genomics and Transcriptomics with Droplet Microfluidics Adam Abate, PhD Drug and Diagnostics Development
Integrative Pharmacology Approach to Understand Mechanisms of Tuberculosis Drug Resistance Rada Savic, PhD Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development
Metagenomic Contributions to Type 2 Diabetes Among Filipino Populations Mark Seielstad, PhD Transfusion Medicine, Diabetes, Genetics, Epidemiology and Surveillance
Influence of Heme on Hepatic Cytochrome P450 Turnover Maria Correia, PhD Drug and Diagnostics Development
Discovery of Oxaboroles as New Antimalarial Agents Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
VEGF signaling in placental development and disease Susan Fisher, PhD Immunology, Labor and Delivery
Transition zone control of ciliary signaling Jeremy Reiter, MD, PhD Genetics

Active Investigators: 85