Dementia and Cognitive Impairment

Active Projects: 34

Project Investigator All Topics Start date End date
The Psychiatric Cell Map Initiative: Connecting Genomics, Subcellular Networks, and Higher Order Phenotypes Nevan Krogan, PhD, MSc Dementia and Cognitive Impairment
Closing the gap between observational research and randomized trials for prevention of Alzheimer's Disease and dementia Maria Glymour, ScD, MS Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
The inverse association between cancer and Alzheimers disease: comparing spurious and causal explanations to illuminate the causes of Alzheimers disease Maria Glymour, ScD, MS Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Infectious Disease, HIV/AIDS, Tuberculosis, Malaria, Surgery and Anesthesia, Cancer/Oncology, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Eye Disease and Blindness, Oral Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Pediatrics, Policy and Standards of Care, Epidemiology and Surveillance
A cross-national perspective on social integration and cognitive aging for Mexican-origin adults in the U.S. and Mexico: Quantifying the effects of both local and cross-border social integration Jacqueline Torres, PhD Dementia and Cognitive Impairment, Aging
Lifecourse health, cerebral pathology and ethnic disparities in dementia Maria Glymour, ScD, MS Dementia and Cognitive Impairment
Neuropathological changes underlying clinical heterogeneity in Alzheimer disease Neurology and Mental Health, Dementia and Cognitive Impairment, Residencies, Fellowships, and Postdoctoral Training
Healthy Heart, Healthy Brain? A Pooled Life-course Cohort for Dementia Risk Assessment Kristine Yaffe, MD Dementia and Cognitive Impairment
Effect of Passive Immunization on the Progression of Mild Alzheimer's Disease: Solanezumab(LY2062430) versus Placebo Adam Boxer, MD, PhD Pharmacology and Drug Treatment, Dementia and Cognitive Impairment
Sleep, cognitive decline and dementia-a comparison between China and the US Yue Leng, PhD Dementia and Cognitive Impairment
Effects of Polydrug Use, Adulterants and HIV on Cardiac Injury in Homeless Women Elise Riley, PhD Dementia and Cognitive Impairment, Women's Health, Access or Barriers to Care, Stigma and Discrimination, Substance Abuse
Interventions for Symptom Management in Older Patients with HAND Victor Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical Trajectories Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD
Understanding literacy acquisition through immersion in foreign languages Fumiko Hoeft, MD, PhD Dementia and Cognitive Impairment
Traumatic brain injury education Alisa Gean, MD Neurology and Mental Health, Dementia and Cognitive Impairment
Epidemiology of stroke Anthony Kim, MD Cardiovascular Disease, Neurology and Mental Health, Dementia and Cognitive Impairment
Community-based pediatric rehabilitation in India Mitul Kapadia, MD, MPH Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Pediatrics, Access or Barriers to Care
Global Brain Health Institute Victor Valcour, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment, Training International Scholars and Clinicians, Residencies, Fellowships, and Postdoctoral Training
A Multicenter, Multinational, Randomized, Double Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Laquinimod (0.5, 1.0 and 1.5 mg/day) as Treatment in Patients with Huntington's Disease Michael Geschwind, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
ACC: Callosal Agenesis as a Window into Common Neurodevelopment Disorders Elliott Sherr, MD, PhD Genetics, Neurology and Mental Health, Dementia and Cognitive Impairment
Testosterone's role in sex-specific outcomes after early anesthesia Jeffrey Sall, PhD, MD Surgery and Anesthesia, Neurology and Mental Health, Dementia and Cognitive Impairment, Pediatrics, Adolescent Health
Science-based Innovation in Learning Center for ELL and LD Fumiko Hoeft, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment, Pediatrics, Patient and Peer Education
Predictors of Cognitive Aging across the Lifecourse Kristine Yaffe, MD Noncommunicable and/or Chronic Disease, Neurology and Mental Health, Dementia and Cognitive Impairment, Risk Reduction and Prevention
Track TBI Biorepository Subcontract Geoffrey Manley, MD, PhD Dementia and Cognitive Impairment
The Frontotemporal Lobar Degeneration Clinical Research Consortium Adam Boxer, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease Yue Leng, PhD Dementia and Cognitive Impairment
State of the Future in Global Aging, Dementia & Mental Health: Bridging Leadership, Science, Practice and Policy Caroline Stephens, RN, PhD Dementia and Cognitive Impairment
Diffusion Tensor Imaging Processing and Group Analysis Neurology and Mental Health, Dementia and Cognitive Impairment
Lifecourse health, cerebral pathology and ethnic disparities in dementia Maria Glymour, ScD, MS Dementia and Cognitive Impairment
Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in a Multiethnic Cohort of Oldest-Old Maria Glymour, ScD, MS Dementia and Cognitive Impairment
Genetic architecture of memory and executive functioning in Alzheimer's disease Glymour Subcontract with University of Washington. PI: Paul Crane Reference: Grant number 1A01AG042437-01A1 Maria Glymour, ScD, MS Neurology and Mental Health, Dementia and Cognitive Impairment
Psychometric Integrative Technology for Cognitive Health Research Maria Glymour, ScD, MS Neurology and Mental Health, Dementia and Cognitive Impairment
Predicting progression of human prion disease Michael Geschwind, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
Environment and cognitive decline in older hispanics Mary Haan, DrPH, MPH Dementia and Cognitive Impairment, Aging

Active Projects: 57

Project Investigator All Topics Start date End date
Developing low-cost cognitive tools for dementia assessment in low-to-middle income countries (LMICs) Dementia and Cognitive Impairment
A Double-Blind, Placebo-Controlled, Randomized, Parallel Group, 12-Month Safety and Efficacy Trial of Leuco-methylthioninium bis(hydromethanesulfonate) in Subjects with Behavioral Variant Frontotemporal Dementia (bvFTD) Adam Boxer, MD, PhD Dementia and Cognitive Impairment
Heart rate variability as a biomarker of prodromal PD Samuel Goldman, MD, MPH Neurology and Mental Health, Dementia and Cognitive Impairment
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases Michael Geschwind, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
Study of Osteoporotic Fractures Kristine Yaffe, MD Dementia and Cognitive Impairment, Women's Health, Aging
Developing Tau Prion Therapeutics for Chronic Traumatic Encephalopathy Noncommunicable and/or Chronic Disease, Dementia and Cognitive Impairment, Trauma and PTSD
ALS Center of Excellence at UCSF Dementia and Cognitive Impairment
Formation and Spreading of Tau Prions in Chronic Traumatic Encephalopathy Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment, Residencies, Fellowships, and Postdoctoral Training
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Effectiveness, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, Policy and Standards of Care, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training
Undiagnosed PD in the ED: Unrealized Opportunity for Early Intervention Sopiko Jimsheleishvili, MS Dementia and Cognitive Impairment
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Drug and Diagnostics Development, Dementia and Cognitive Impairment
Epidemiology of Functional Status in Elderly Hispanics Mary Haan, DrPH, MPH Dementia and Cognitive Impairment
Long-Term Central Nervous System (CNS) Consequences of Treatment during Acute Infection Victor Valcour, MD, PhD Dementia and Cognitive Impairment
Creating Maps of 4D Brain Images to Unravel Dementia Heterogeneity of Aging HIV Population Victor Valcour, MD, PhD Drug and Diagnostics Development, Dementia and Cognitive Impairment
Frontotemporal Dementia: Genes, Images, and Emotions Dementia and Cognitive Impairment
HIV Tropism, Persistence, Inflammation, and Neurocognition in Therapy Initiation Richard Price, MD HIV/AIDS, Dementia and Cognitive Impairment
Burden, Depression, and Health in Dementia Caregivers: the Role of Emotion Neurology and Mental Health, Dementia and Cognitive Impairment
Accelerated Biological Aging in Schizophrenia Dementia and Cognitive Impairment
Phase I Multiple Ascending Dose Trial of the MT Stabilizer TPI-287 for Alzheimer Disease (AD) Adam Boxer, MD, PhD Pharmacology and Drug Treatment, Dementia and Cognitive Impairment
Variations in Brain Functional Complexity Across Neurodegeneration Dementia and Cognitive Impairment
Extension of Phase II Studies ABE4869g and ABE4955g in Patients with Mild to Moderate Alzheimer Disease Adam Boxer, MD, PhD Dementia and Cognitive Impairment
Towards Therapeutics for Neurodegenerative Diseases Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
Phase II Study to Evaluate the Efficacy and Safety of MABT5102A in Patients with Mild to Moderate Alzheimer's Diseases Adam Boxer, MD, PhD Dementia and Cognitive Impairment
Medical Scientist Training Program Noncommunicable and/or Chronic Disease, Cancer/Oncology, Dementia and Cognitive Impairment, Residencies, Fellowships, and Postdoctoral Training, UCSF Professional Education
UCSF - GAP Collaboration: Leveraging the Brain Health Registry for GAP Clinical Trial Recruitment Neurology and Mental Health, Dementia and Cognitive Impairment
Childhood Lead Poisoning Prevention George Rutherford, MD Occupational and Environmental Disease, Dementia and Cognitive Impairment, Pediatrics, Systematic Reviews and Guideline Development
Four Repeat Tauopathy Neuroimaging Initiative Adam Boxer, MD, PhD Dementia and Cognitive Impairment
Aging Among the Homeless: Geriatric Conditions, Health and Healthcare Outcomes Margot Kushel, MD Dementia and Cognitive Impairment, Trauma and PTSD, Access or Barriers to Care, Stigma and Discrimination, Substance Abuse
Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression Dementia and Cognitive Impairment
Social Resources That Preserve Functional Independence After Memory Loss Maria Glymour, ScD, MS Dementia and Cognitive Impairment
Molecular Pathogenesis of Age Dependent Neurodegeneration Neurology and Mental Health, Dementia and Cognitive Impairment
The effects of alcohol on acute HIV associated neurocognitive disorders Christopher Pilcher, MD HIV/AIDS, Dementia and Cognitive Impairment, Substance Abuse
The Translational Alzheimer Disease Research Program Dementia and Cognitive Impairment
HIV-associated neurocognitive impairment and antiretroviral adherence: secondary data analysis of the THINK2 prospective cohort study Laura Saucier, MS HIV/AIDS, Dementia and Cognitive Impairment
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Sequential Cohort, Dose-Ranging Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TPI-287 in Patients with Mild to Moderate Alzheimer's Disease Adam Boxer, MD, PhD Noncommunicable and/or Chronic Disease, Dementia and Cognitive Impairment
National Alzheimer's Coordinating Center, NACC Dementia and Cognitive Impairment
Eye Movement Control in Normal Elderly and MCI Adam Boxer, MD, PhD Noncommunicable and/or Chronic Disease, Dementia and Cognitive Impairment
Predictors of MCI/Dementia among the Oldest Old Women Kristine Yaffe, MD Dementia and Cognitive Impairment, Women's Health
PET ligands for measuring tau in the brains of combatants after traumatic brain injury. Dementia and Cognitive Impairment, Trauma and PTSD
Peripheral Reservoir of HIV Monocytes Pivotal to Cognition in HIV Victor Valcour, MD, PhD HIV/AIDS, Neurology and Mental Health, Dementia and Cognitive Impairment
MRI Signature of PD Heterogeneity Dementia and Cognitive Impairment
Alameda MHSA-Early Intervention at Onset of First Psychosis Dementia and Cognitive Impairment, Adolescent Health
Pilot Trial in Wearable computing technology in mild to moderate Alzheimer's type Dementia: development of an Automated Reality Orientation App Pierre Theodore, MD Dementia and Cognitive Impairment
New Approaches to Dementia Heterogeneity Neurology and Mental Health, Dementia and Cognitive Impairment
HIV-1 Specific Immune Responses in Thai Individuals with HIV Dementia Victor Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment
Predictors & Outcomes of Cognitive Trajectories in the Oldest of Old Kristine Yaffe, MD Dementia and Cognitive Impairment
Dementia in HIV Patients over 60 Years of Age Victor Valcour, MD, PhD HIV/AIDS, Neurology and Mental Health, Dementia and Cognitive Impairment
Isolated Executive Impairment and Cognitive Decline Julene Johnson, PhD Dementia and Cognitive Impairment
Racial Disparities in Cognitive Impairment Health Outcomes PA00-019 Kala Mehta, DSc, MPH Dementia and Cognitive Impairment
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia HIV/AIDS, Dementia and Cognitive Impairment
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia HIV/AIDS, Dementia and Cognitive Impairment
UCSF-Kaiser Building Interdisciplinary Research Careers in Women's Health Program Ruth Greenblatt, MD HIV/AIDS, Noncommunicable and/or Chronic Disease, Cancer/Oncology, Cardiovascular Disease, Diet, Exercise, and Obesity, Dementia and Cognitive Impairment, Women's Health, UCSF Professional Education
Development and Validation of a Diagnostic Tool for HIV Dementia HIV/AIDS, Dementia and Cognitive Impairment
Effect of Cognitive Remediation on BDNF Levels in Schizophrenia Dementia and Cognitive Impairment
California Non-AD Diagnostic Reliability Consortium Julene Johnson, PhD Dementia and Cognitive Impairment, Aging
Managing Diagnostic Uncertainty: An Examination of the Interplay of Technology, Medical Knowledge, and Law in Diagnostic Practice. The Case of Epilepsy Vincanne Adams, PhD Dementia and Cognitive Impairment, Systematic Reviews and Guideline Development