NIH National Institute of Allergy and Infectious Disease

289 Archived Projects

Title Investigator Start
End
Evaluation of Falcipain as an Antimalarial Drug Target Rosenthal
Population Genetics of the PO1 Locus of SIV and HIV-1 Delwart
San Francisco STDs CRC Padian
Adult AIDS Clinical Trials Unit (AACTU) Havlir
Penicillin Interactive Proteins of Staphylococcus Aureus Chambers
The Zimbabwe-San Francisco HIV Prevention Trials Unit Chipato
Biology of Infectious Diseases Training Program [I] Chambers
UCSF AIDS Research Training Program
Immunomodulation of Transplant Rejection by Anti-CD3 mAb Bluestone
STD Risks and Latino Adolescents' Sexual Networks Padian
Drug Resistant Malaria Clinical and Laboratory Studies Staedke
Role of MmpL Transporters in M. Tuberculosis Virulence Cox
Population-Based Molecular Epidemiology of Tuberculosis Hopewell
Collaborative Network for Clinical Research on Immune Tolerance Bluestone
Collaborative Network for Clinical Research on Immune Tolerance - Offcampus Portion Bluestone
Spontaneous Autoimmune Model of Peripheral Neuropathy Bluestone
Double-Stranded RNA Virus in Giardia Wang
Therapeutic Strategies for HIV Disease Havlir
Immunologic and Virologic Features of Early HIV Infection
T Regulatory Cells and T Cell Activation in HIV Disease Deeks
A Chemical Map of T Cell Signaling Shokat
Recombinant Picornaviruses as AIDS Vaccines Andino-Pavlovsky
Novel Anti-Malarials by Combinatorial Pharmacogenomics Derisi
Mechanisms of Bartonella Virulence in AIDS Patients Koehler
RNA Protein Interactions in Poliovirus Replication Andino-Pavlovsky
The Connie Wofsy Womens' HIV Study Greenblatt
Treatment Intensification for Drug-Resistant HIV Deeks
CD4+ T Cell Receptors in Leishmaniasis Locksley
Host Protein Degradation by Schistosome Parasites McKerrow
Role of Innate Immunity in Controlling HIV Infection
Clinical and Molecular Studies of Drug Resistant Malaria [I] Rosenthal
Phase 1/2 Trial of Pharmacological HIV-1 Prevention Page
Predicting Resistance: Validating Mathematical Models Lietman
Regulation of the Development of Tryanosoma brucei Wang
WIHS Treatment Exposure and Viral Rebound Study / AIDS Research Greenblatt
Role of Notch 1 in Immunie Tolerance Bluestone
Purine Metabolism in Trichomonas Vaginalis Wang
Targeting Cysteine Proteases--Antiparasitic Chemotherapy McKerrow
An Intervention for Male STD Patients in India / HIV Related Lindan
Host Polymorphisms and Uncomplicated Malaria Parikh
Sexually Transmitted Infections Clinical Trials Group (STICTG) Giudice
Clinical Studies of Interactions Between HIV and Malaria Havlir
Immunomodulation of Transplant Rejection by Anti-CD3 mAb Bluestone
The Determinants of T Cell Activation in HIV Infection Hunt
Falcipain Cysteine Proteases of Malaria Parasites Rosenthal
Mechanisms of Leukocyte Integrin Signaling Lowell
Utility of Rapid Diagnostic Tests for Malaria Hopkins
Training in HIV Translational Research Havlir
Assessing Antiretroviral Exposure in Diverse Populations Gandhi
RNAi as an Intercellular Antiviral Defense Mechanism Andino-Pavlovsky
Assessing Laboratory Correlates of Immune Protection McCune
Dissecting the HLA Contribution to Rheumatoid Arthritis
HIV Effects on the Central Hematolymphoid System McCune
Thymic Function in Adults With HIV-1 Disease McCune
Coming Together to Overcome HIV/AIDS in Zimbabwe and Zambia Padian
Secretion of Virulence Factors by Mycobacterium tuberculosis Cox
Innate NKT Cells in HIV Infection Nixon
Viral Tropism and Immune Control in HIV Nixon
Cell Mediated Immunity in HIV-Infected Children Nixon
Anti-Gag Antibodies and Enhancement of Lentiviral Disease Progression McCune
T Regulatory Cells in HIV Infection Nixon
Tissue-Based Small Animal Model for HIV Drug Discovery
University of Zimbabwe-UCSF Clinical Trials Unit Chirenje
UCSF HIV Clinical Trials Unit Havlir
Role of Innate Immunity in Controlling HIV Infection
Genetic Diversity as a Determinant of Viral Pathogenesis and Attenuation Andino-Pavlovsky
Preventing the Establishment of Enfuvirtide-Resistance in the Latent Reservoir Deeks
Spontaneous Autoimmune Model of Peripheral Neuropathy Bluestone
Virologic and Host Factors Contributing to HIV Control in Elite Controllers Hatano
Resequencing Microarray for Rapid Detection and Antimicrobial Resistance Profiling
Innate Natural Killer T (NKT) Cells in HIV Infection Nixon
A Clinical Trial for Uncomplicated Skin Infections in Areas of Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus (MRSA) Chambers
Development of Botulinum Neurotoxin Immunotherapy, Serotypes C, D, F, and G Marks
Reproductive Infectious Disease (RID) Fellowship Cohen
Oxygen Sensors and P450 Monooxgenases in Mycobacterium tuberculosis Ortiz De Montellano
Population-Based Molecular Epidemiology of Tuberculosis in San Francisco Hopewell
Role of Innate Immunity in Controlling HIV Infection
UCSF-Gladstone Center for AIDS Research (CFAR) Volberding
Biology of Infectious Diseases Training Program [II] Chambers
Cervical Maturity, Mucosal Immunity, and Chlamydia trachomatis Infections Hwang
The Connie Wofsy Women's HIV Study Greenblatt
Translation Regulation in Giardia lamblia Wang
Therapeutic Strategies for HIV Disease Havlir
Oral Wash for Nucleic Acid Diagnosis and Prognosis of TB in HIV-infected Ugandans Davis
Mechanisms of Bartonella Virulence in AIDS Patients Koehler
Initiation of Allergic Immunity by Parasites Locksley
Resistance of Malaria Parasites to Artemisinin-Based Combination Therapies Rosenthal
Translational Studies of Plasmodium Falciparum Infection Dynamics Greenhouse
Virus Detection Using Microarrays and Characterization of a Novel Cardiovirus Chiu
Regulatory T Cell Influence on Infant and Adult Immune Responses to HIV Hartigan-O'Connor
Human Endogenous Retroelements in HIV Immunopathogenesis Nixon
Molecular Mechanisms of Plasmodium falciparum Adherence to the Human Placenta Fisher
Innate Immune Response Genetics and T cell Activation in Treated HIV Infection Hunt
Regulation of the Development of Trypanosoma brucei Wang
Resistance of Malaria Parasites to Artemisinin-Based Combination Therapies Rosenthal
Regulation of ESX-1 secretion and its role in M. tuberculosis virulence Cox
Microbial Pathogenesis and Host Defense Engel
HPV Epidemiology and Response to Screening (HEARTS) Riley
Role of Innate Immunity in Controlling HIV Infection
Effect of Drug Resistance on Transmissibility and Pathogenicity of M. Tuberculosis Hopewell
Manipulation of Macrophage Responses by M. tuberculosis Cox
Interruption of Maternal-Fetal Transmission of HIV McCune
Oral Wash for Nucleic Acid Diagnosis and Prognosis of TB in HIV-Infected Ugandans Davis
An Endogenous Retroelement Vaccine against HIV-1 Nixon
Utility of Contact Investigation of Drug Susceptible and Resistant Tuberculosis in Tanzania Fair
Early Mortality in HIV-Infected Patients Starting Antiretroviral Therapy in Africa Geng
The Impact of Early Antiretroviral Therapy on HIV Persistence and Inflammation Deeks
The Impact of CD8 T Cells on Viral Control and Evolution in HIV-Infected Infants Feeney
Regulation of ESX-1 Secretion and Its Role in Mycobacterium tuberculosis Virulence Cox
Regulation of the Development of Trypanosoma brucei Wang
HIV Status and Reproductive Aging Affect Liver Fibrosis in HIV/HCV Infected Women Peters
Protective Immunity in HIV Highly Exposed but Uninfected Subjects Nixon
HIV Effects on the Central Hematolymphoid System McCune
An Automated High Throughput Phenotypic Screen for Schistosomiasis Drug Discovery Caffrey
Inflammation, T Cell Senescence, and Mortality in Treated HIV Infection Hunt
Gene Circuits that Control Morphology in Histoplasma Sil
Mechansims of poliovirus replication Andino-Pavlovsky
Immunological Detection and Control of Experimental Uncomplicated Malaria Kim
Bay Area Hepatitis C Cooperative Research Center McCune
The Connie Wofsy Women's HIV Study Greenblatt
Dissecting the HLA contribution to Rheumatoid Arthritis
Program for Resistance, Immunology, Surveillance, and Modeling of Malaria in Uganda (PRISM) Dorsey
Health Empowerment for MSM in South Africa Lane
Protective immunity in HIV Highly Exposed but Uninfected Subjects Nixon
The Impact of Tolerance in the Newborn on Lentiviral Infection McCune
Tuberculosis Epidemiology and Novel Transmission Routes in Rural Tanzania Hopewell
Lead Identification to Clinical Candidate Selection: Drugs for Chagas' Disease McKerrow
Innovative Methods for Measuring Antiretroviral Exposure Greenblatt
UZ-UCSF Collaborative Research Program Miller
Training in HIV Translational Research Havlir
Spontaneous Autoimmune Model of Peripheral Neuropathy Bluestone
A Rapid Pan-Viral Microarray Diagnostic for Category A-C Biodefense Pathogens Chiu
Oral Wash for Nucleic Acid Diagnosis and Prognosis of TB in HIV-Infected Ugandans Davis
UCSF-GIVI Center for AIDS Research . Volberding
The Impact of Early Antiretroviral Therapy on HIV Persistence and Inflammation Deeks
UZ-UCSF Clinical Trials Unit Chirenje
Global Health Comparative Effectiveness: A Data Synthesis Method Applied to HIV Kahn
Replication, Pathogenesis and Evolution of RNA Viruses, Including Dengue Andino-Pavlovsky
Chemical Methods for Ferrous Iron Targeted Drug Delivery Renslo
Human Immune System Layering and the Neonatal Response to Vaccines McCune
Improving Early Identification of Drug Resistant Tuberculosis in HIV Prevalent Settings Metcalfe
Effector and Regulatory T Cell Responses and Protection from Clinical Malaria Feeney
Parasite Immunity Orchestrated by Th2 Cells Locksley
The impact of antimalarials and insecticide resistance on malaria transmission in Uganda Conrad
A Novel APOBEC-Based Vaccine Approach for HIV Nixon
Molecular Epidemiology and Geospatial Analysis of Tuberculosis Transmission in Uganda Chamie
Immunomodulation of transplant rejection by anti-CD3 mAb Bluestone
Structure-Aided Design of CYP51 Inhibitors for Treatment of Parasitic Infections Podust
Sputum M. tuberculosis DNA Kinetics during TB Treatment in Patients with HIV Everett
TB Guideline Observation and Adherence in Low Income Countries (TB GOAL) Cattamanchi
DARE: Delaney AIDS Research Enterprise to Find a Cure Deeks
Protein homeostasis mechanisms underlying enterovirus replication and evolution Andino-Pavlovsky
Immunological Detection and Control of Experimental Uncomplicated Malaria Kim
Structural and functional studies of M. tuberculosis type VII secretion Rosenberg
Discovery of Oxaboroles as New Antimalarial Agents Rosenthal
Thymic Medullary Epithelial Cell Turnover and Control of Immune Tolerance
Plugging Hair ARV Levels as Adherence Biomarkers into HIV Prevention Trials Gandhi
Signaling by Cytoplasmic Tyrosine Kinases in Leukocytes Lowell
Fetal HCMV Infection: Role of the Human Placenta Pereira
Discovery of Oxaboroles as New Antimalarial Agents Rosenthal
Molecular Dissection of Histoplasma-Induced Host-Cell Death Sil
Trefoil Factors Regulate Th2 Immunity Herbert
Immunologic Consequences of Highly Effective Antimalarial Chemoprevention Jagannathan
Host-pathogen Interactions during Vertical Transmission of Listeria monocytogenes Ross
The Hair Trigger Study Greenblatt
Evaluating Re-active Surveillance Strategies for Malaria Elimination in Swaziland Hsiang
HIV cure with CCR5 (-) human IPS hematopoietic stem cells
Impact of HIV-Associated Inflammation on Disease Deeks
Reducing Failure-to-Initiate ART: Streamlined ART Start Strategy (START) Havlir
Innate NKT Cells in HIV Infection Nixon
A Novel Proteomic Approach to Tuberculosis Biomarker Discovery using Human Exosomes Davis
IDO-induced Tryptophan Catabolism and Mortality in Treated HIV-infected Africans Hunt
Novel Mechanisms of Beta-Lactam Resistance in Staph aureus Chambers
Layering of the Human Immune System, Viral Infections, and Childhood Asthma McCune
Biology of Infectious Diseases Training Program [III] Chambers
Recent Advances in AIDS and HIV Research Volberding
Oxygen Sensors and P450 Monooxygenases in Mycobacertium tuberculosis Ortiz De Montellano
UCSF-GIVI Center for AIDS Research (CFAR) Volberding
Novel approaches to identify host genes required for Chlamydia pathogenesis Engel
Novel Mechanisms of Beta-Lactam Resistance in Staph Aureus Chambers
The Connie Wofsy Women's HIV Study Greenblatt
Mechanisms of Neutrophil Activation Lowell
Generation of Therapeutic Antibodies for Serotype F Botulism Marks
TB Surrogate Markers for Assessing Response to Treatment (TB SMART Study) Nahid
Heat Shock Protein 90 and HIV Persistence
Chemical Methods for Ferrous Iron Dependent Drug Delivery Renslo
Exploring Statins As a Small Molecule Therapy for Treatment of Schistosomiasis Caffrey
Mobile Health for Implementation of Home-based TB Contact Investigation in Uganda Davis
Initiation of allergic immunity by parasites Locksley
2013 NIH Workshop on Protein Homeostasis and Viral Infection Andino-Pavlovsky
Bartonella: dissecting niche-specific adaptation in a human pathogen Koehler
HIV, HCV, and gender effects on Liver, Bone, and Vascular Health Tien
High throughput proteomics to dissect Chlamydia-host cell interactions Engel
Role of Innate Lymphoid Cells in Autoimmunity Bluestone
Novel flow cytometry-based assay for HIV-infected cells McCune
UZ-UCSF Clinical Trials Unit Chirenje
HIV Viral Reservoirs and Monocyte Activation in HIV-Associated Atherosclerosis Hsue
Hair measures to assess adherence and explain outcomes in an HIV clinical trial Gandhi
HIV cure with CCR5 negative human IPS hematopoietic stem cells
Determinants of Functional Immune Defects in Treated HIV Infection and Aging Hunt
Plasmodium Falciparum Infection and Interference with Effective B Cell Memory Greenhouse
Interaction between Innate and Th2 Lymphocytes in Helminth Immunity Nussbaum
Mentoring Translational Researchers for Careers in Pediatric Global Health Feeney
Trispecific Monoclonal Antibody for Botulinum Neurotoxin Intoxication Therapy Marks
Regulatory Circuits That Link Cell Fate and Virulence in Histoplasma Capsulatum
Genetic Diversity as a Determinant of Viral Adaptation and Pathogenesis Andino-Pavlovsky
Microbial Pathogenesis and Host Defense Engel
Evaluation of Novel Tuberculosis Screening Strategies for People living with HIV Yoon
Resistance of Malaria Parasites to Artemisinin-Based Therapies Rosenthal
Quantitative mapping of interactions between dengue virus and its hosts Shah
Regulation of Innate Immune Signaling by Lyn Kinase Lowell
Timing of ART and homeostasis of the persistent HIV reservoir in the adult McCune
Pharmacodynamics of Antimalarial Chemoprevention Rosenthal
Childhood Tuberculosis Infection Among School-Age Children in Rural Uganda Marquez
Microfluidic PCR Method to Identify and Characterize HIV-Infected Single Cells Henrich
Interferon-independent mechanisms of malaria restriction by helper T cells McCune
Gene circuits that control morphology in Histoplasma Sil
Generation of therapeutic antibodies for serotype F botulism (Continuation of A120963 from NIH G Pool to Subaccount) Marks
Mechanisms of Neutrophil Activation Lowell
The Connie Wofsy Women's HIV Study Greenblatt
Chemoprophylaxis for HIV Prevention: Analysis of Bone and Metabolic Effects Glidden
Reducing Failure-to-Initiate ART: Streamlined ART Start Havlir
Novel Mechanisms of Beta-lactam Resistance in Staph Aureus, Continuation A120553 Chambers
Preclinical Development of MucoCept Cohen
Proteomics Analysis of Host-Pathogen Interactions in Histoplasma Sil
Childhood Tuberculosis Infection Among School-Age Children in Rural Uganda Marquez
Novel methods of pharmacologic monitoring for multidrug resistant tuberculosis treatment in the setting of HIV infection Metcalfe
Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophages Cox
The impact of TB co-infection on the reservoir of persistent HIV in vivo McCune
Host-Directed Strategies to Create Synergistic Antibacterial Therapies Cox
Impact of Chemotherapy and Stem Cell Transplant on HIV-1 Reservoir Dynamics Henrich
Plugging Hair ARV Levels as Adherence Biomarkers into HIV Prevention Trials Gandhi
Mechanism of enterovirus replication Andino-Pavlovsky
New approaches to study Pseudomonas-host interactions Engel
Regulatory circuits and virulence in candida albicans
Real-Time Unbiased Pathogen Detection in Febrile Illnesses by Nanopore Sequencing Chiu
Targeting Allosteric Sites to Modulate Protein Interactions and Function Craik
Comparison of Pharmacologic Markers of Exposure to HIV Pre-Exposure Prophylaxis Glidden
TB Surrogate Markers for Assessing Response to Treatment (TB SMART Study) Nahid
A Novel Microfluidic HIV-1 Co-Culture Assay to Quantify Latent Reservoirs Henrich
Novel serologic assays of P. falciparum exposure for improved surveillance in control and elimination Greenhouse
Fetal HCMV Infection: Role of the Human Placenta Pereira
Effector and regulatory T cell responses and protection from clinical malaria Feeney
Improving the molecular diagnosis of drug resistant tuberculosis Kato-Maeda
Discovery of Oxaboroles as New Antimalarial Agents Rosenthal
Chemical Methods for Ferrous Iron Dependent Drug Delivery Renslo
Initiation of allergic immunity by parasites Locksley
Bartonella: dissecting niche-specific adaptation in a human pathogen Koehler
Program for Resistance, Immunology, Surveillance & Modeling of Malaria in Uganda Dorsey
HIV, HCV, and gender effects on Liver, Bone, and Vascular Health Tien
Delaney AIDS Research Enterprise to Cure HIV Deeks
Training in HIV Translational Research Havlir
Single Cell Characterization of Latent HIV-1 Reservoirs Henrich
Recent Advances in AIDS and HIV Research Volberding
Biology of Infectious Diseases Training Program Chambers
Targeting latent HIV-1 Reservoirs with the Antibody-Drug Conjugate, Brentuximab Vedotin Henrich
Fetal Zika virus infection: role of the human placenta Pereira
Simplified Isoniazid Preventive Therapy (SPIRIT) Strategy to Reduce TB Burden Havlir
Identification of diagnostic and prognostic host biomarkers of Zika virus infection by transcriptome profiling Chiu
Novel Therapeutics for Treatment of River Blindness and Lymphatic Filariasis Sakanari
Hair Extensions;: Using Hair Levels to Interpret Adherence, Effectiveness and Pharmacokinetics with Real-World Oral PrEP, the Vaginal Ring, and Injectables Gandhi
Therapeutic vaccination and PD-1 blockade in treated HIV disease Deeks
Protein secretion in bacterial pathogens Rosenberg
The Immunologic Impact of In Utero Malaria Exposure and Prenatal Chemoprevention Prahl
Mentoring Multidisciplinary Patient-Oriented Research in Engagement in HIV Care Geng
Mentoring in Patient Oriented Research on Food Insecurity, HIV and Aging, Weiser K24 Weiser
Point-of-care C-reactive protein-based tuberculosis screening among people living with HIV: planning a comparative effectiveness trial Yoon
The Bixby Center for Global Reproductive Health - Annual Research Day Conference Chirenje
Adapting to a changing environment: How surface contact induces virulence factor production in Pseudomonas aeruginosa Engel
Sputum Transcriptomic Expression Profiling in Study 31: Express 31 Nahid
Novel Mechanisms of Beta-lactam Resistance in Staph Aureus Chambers
UCSF-Gladstone Center for AIDS Research Volberding
Recent Advances in AIDS and HIV Research Volberding
Biology of Infectious Diseases Training Program Chambers
Elucidating the mechanism of macrophage death during infection with the AIDS-associated opportunistic pathogen Histoplasma capsulatum Sil
Cellular and Bacterial Dynamics in Tuberculosis Ernst
Antigen export in M. tuberculosis evasion of CD4 T cells Ernst
HPMI: Host Pathogen Mapping Initiative Krogan
Chemical Methods for Ferrous Iron Dependent Drug Delivery Renslo
Insect adaptive immunity Andino-Pavlovsky
Statistical methods for clinical trials of novel PrEP agents Glidden
Point-of-care Urine Monitoring of Adherence (PUMA): Testing a Real-Time Urine Assay of Tenofovir in PrEP Gandhi
Placental malaria: The role of inflammation at the maternal-fetal interface Valderramos
EV71 intra-host evolution, attenuation and vaccine development Andino-Pavlovsky
Discovery of Novel Antimalarial Leads Targeting Translational Repression in Plasmodium parasites Renslo
Using Genetics and Genomics to Dissect Coccidioides Spherulation Sil
Understanding the epidemiology and natural history of unrecognized Ebola virus infection Kelly
Seroepidemiologic methods to identify hotspots of trachoma and predict future infection Arnold
New Serological Measures of Infectious Disease Transmission Intensity Arnold