WHO Cochrane Project: Antiretroviral Therapy Project

Sponsor: World Health Organization (WHO)

Location(s): United States


The Prevention and Public Health Group (PPHG)  at UCSF coordinates and conducts public health and epidemiological research. PPHG works closely with the Centers for Disease Control and Prevention (CDC); President's Emergency Plan for AIDS Relief (PEPFAR); World Health Organization (WHO); Joint United Nations Program on HIV/AIDS (UNAIDS); the Global Fund to Fight AIDS, Tuberculosis, and Malaria; and the National Institutes of Health (NIH). 

n early 2009, the World Health Organization (WHO) commissioned GRADE Evidence Profiles from the Cochrane HIV/AIDS Group as the evidence base for updating two WHO guidelines: one on antiretroviral therapy for HIV infection in adults and adolescents, and the other on antiretroviral drugs for treating pregnant women and preventing HIV infection in infants.

By September 2009 the Cochrane HIV/AIDS Group presented WHO with the findings from the systematic reviews and the GRADE Evidence Profiles. Following consensus meetings at WHO, involving experts and stakeholders from around the world, and with presentations from the Cochrane HIV/AIDS Group, the WHO released its ‘rapid advice’ preliminary guidance in November 2009.