A Randomized Controlled Trial of Vitamin D Supplementation in Multiple Sclerosis
Location(s): United States
Assess the effectiveness of vitamin D supplementation in patients with multiple sclerosis (MS). This trial is being done because previous studies of vitamin D levels in people with MS show that those with lower vitamin D levels are more likely to have MS attacks and new MS lesions develop on brain MRI, but it is not known if giving vitamin D supplements reduces the amount of MS activity.
This is a multicenter trial in which participants with relapsing-remitting MS will be receive high-dose or low-dose vitamin D for two years. All participants will be given glatiramer acetate (Copaxone) for free during the study. The purpose of the study is to assess if vitamin D is effective in reducing relapses and new MRI lesions in people with multiple sclerosis.