Postnatal Growth and Retinopathy of Prematurity (G-ROP) Studies

Investigator: Alejandra G. De Alba Campomanes, MD, MPH
Sponsor: Children's Hospital of Philadelphia

Location(s): United States


Retinopathy of prematurity (ROP) is a disease of the eye affecting prematurely-born babiesa leading cause of preventable childhood blindness. Diagnosis involves repeated, stressful, resource-intensive eye examinations. Under current screening guidelines, less than 5% of infants require laser surgery. Slow postnatal growth, a surrogate measure for low serum insulin-like growth factor 1 (IGF-1), is associated with subsequent development of severe ROP and can be used to predict which infants are at risk for severe ROP and therefore require eye exams.