PCB Disruption of Thyroid Hormone Action During Development

Investigator: Tracey Woodruff, PhD, MPH
Sponsor: University of Massachusetts

Location(s): United States


Thyroid hormone is essential for normal brain development. This study  examines the mechanisms by which thyroid hormone action can be disrupted by polychlorinated biphenyls (PCBs). These chemicals are structurally similar to thyroid hormone. PCBs are known to affect neural development and they can alter circulating levels of thyroid hormone.