Effects of Fluticasone-Salmeterol on Response of Airway Epithelium to Rhinovirus Infections; Phase IV

Investigator: Homer Boushey, MD
Sponsor: GlaxoSmithKline

Location(s): United States


The purpose of this trial is to determine whether regularly scheduled use of an inhaled long-acting beta agonist (salmeterol) in the setting of concomitant use of inhaled corticosteroids (beclomethasone hydroflouroalkane (HFA) inhaler) will have a detrimental effect on asthma control in people who bear the B16-Arg/Arg genotype of the beta-2 adrenergic receptor gene, as compared to people with asthma of similar severity who bear the B16-Gly/Gly genotype.