Arsenic-induced epigenetic alterations of non-diseased Bangladeshi children
Worldwide, over 100 million people are exposed to potentially carcinogenic levels of arsenic. Bangladesh is home to the largest natural mass poisoning due to arsenic-contaminated drinking water, where one in five deaths can be attributed to chronic arsenic exposure of more than 10 µg/L. Thus far, research has focused on understanding the epigenetic impact of arsenic in healthy and diseased adults as well as diseased children; however, the effects of arsenic exposure in healthy children, defined as children who have had constant high arsenic exposure in utero and early life but have yet to develop a disease, remains unclear.
Mentors: Craig Steinmaus, MD, MPH