Division of Experimental Medicine

Active Projects: 16

Project Investigator All Organizations Start date End date
Mentoring Translational Researchers for Careers in Pediatric Global Health Margaret Feeney, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Trefoil Factor Proteins Modulate Host Immunity against Hookworms Division of Experimental Medicine
Role of Antigen-Specific T Cell Responses in the Control of TB Joel D. Ernst, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Targeting latent HIV-1 Reservoirs with the Antibody-Drug Conjugate, Brentuximab Vedotin Division of Experimental Medicine, AIDS Research Institute
Cellular and Bacterial Dynamics in Tuberculosis Joel D. Ernst, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Timing of ART and homeostasis of the persistent HIV reservoir in the adult Mike McCune, MD, PhD Division of Experimental Medicine, AIDS Research Institute
Microfluidic PCR Method to Identify and Characterize HIV-Infected Single Cells Division of Experimental Medicine, AIDS Research Institute
Impact of Cannabis on Inflammation and Viral Persistence in Treated HIV/SIV Peter Hunt, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Immunologic determinants of age-related macular degeneration Peter Hunt, MD IGHS Faculty Affiliate, Division of Experimental Medicine
The impact of TB co-infection on the reservoir of persistent HIV in vivo Mike McCune, MD, PhD IGHS Faculty Affiliate, Division of Experimental Medicine, AIDS Research Institute
Malaria diagnostic strategies and management of febrile patients in malaria-endemic areas Heidi A. Hopkins, PhD IGHS Faculty Affiliate, Division of Experimental Medicine
Antigen export in M. tuberculosis evasion of CD4 T cells Joel D. Ernst, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Single Cell Characterization of Latent HIV-1 Reservoirs Division of Experimental Medicine, AIDS Research Institute
Impact of Chemotherapy and Stem Cell Transplant on HIV-1 Reservoir Dynamics Division of Experimental Medicine, AIDS Research Institute
Effector and regulatory T cell responses and protection from clinical malaria Margaret Feeney, MD IGHS Faculty Affiliate, Division of Experimental Medicine
HIV Cures - Paving the way towards elimination of HIV persistent CD4 T cell in vivo Division of Experimental Medicine, AIDS Research Institute

Archived Projects: 65

Project Investigator All Organizations Start date End date
Innate NKT Cells in HIV Infection Division of Experimental Medicine
Assessing Laboratory Correlates of Immune Protection Mike McCune, MD, PhD Division of Experimental Medicine
Anti-Gag Antibodies and Enhancement of Lentiviral Disease Progression Mike McCune, MD, PhD Division of Experimental Medicine
Viral Tropism and Immune Control in HIV Division of Experimental Medicine
Chemoprophylaxis and HIV-Host Interactions [II] Division of Experimental Medicine
Thymic Function in Adults With HIV-1 Disease Mike McCune, MD, PhD Division of Experimental Medicine
Immunological Targeting of APOBEC Proteins to Cure HIV Infection Division of Experimental Medicine
Design of an Effective Vaccine against HIV: An Alternative Hypothesis Mike McCune, MD, PhD Division of Experimental Medicine
NIH Director's Pioneer Award Mike McCune, MD, PhD Division of Experimental Medicine
An Endogenous Retroelement Vaccine against HIV-1 Division of Experimental Medicine
HIV Effects on the Central Hematolymphoid System Mike McCune, MD, PhD Division of Experimental Medicine
Protective immunity in HIV Highly Exposed but Uninfected Subjects Division of Experimental Medicine
Tissue-Based Small Animal Model for HIV Drug Discovery Division of Experimental Medicine
Cell Mediated Immunity in HIV-Infected Children Division of Experimental Medicine
The Immune Response to Acute Perinatal HIV Infection Margaret Feeney, MD IGHS Faculty Affiliate, Division of Experimental Medicine
HIV Effects on the Central Hematolymphoid System Mike McCune, MD, PhD Division of Experimental Medicine
Regulatory T Cell Influence on Infant and Adult Immune Responses to HIV Division of Experimental Medicine
Inactivation of HIV-1 by Metalloporphyrin Compounds Division of Experimental Medicine
Oral Drug Treatment for Enhanced Immune Control over HIV Replication Division of Experimental Medicine
HIV Proteomic Center for Host-Viral Responses Characterization Mike McCune, MD, PhD Division of Experimental Medicine
HIV Proteomic Center for Host-Viral Responses Characterization Mike McCune, MD, PhD Division of Experimental Medicine
T Regulatory Cells in HIV Infection Division of Experimental Medicine
Innate Natural Killer T (NKT) Cells in HIV Infection Division of Experimental Medicine
Vitamin A Metabolism and Helminth Infection Mike McCune, MD, PhD Division of Experimental Medicine
Detection and Measurement of the HIV Reservoir Mike McCune, MD, PhD Division of Experimental Medicine
Eliminating the Latent Reservoir through Self-Specific Antibodies Division of Experimental Medicine
The Impact of CD8 T Cells on Viral Control and Evolution in HIV-Infected Infants Margaret Feeney, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Protective Immunity in HIV Highly Exposed but Uninfected Subjects Division of Experimental Medicine
Chemoprohylaxis and HIV-Host Interactions Division of Experimental Medicine
Inflammation and HIV Persistence Mike McCune, MD, PhD Division of Experimental Medicine
Immunological Detection and Control of Experimental Uncomplicated Malaria Division of Experimental Medicine
In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies Mike McCune, MD, PhD Division of Experimental Medicine
A Novel APOBEC-Based Vaccine Approach for HIV Division of Experimental Medicine
Human Endogenous Retroelements in HIV Immunopathogenesis Division of Experimental Medicine
Analysis of HIV-Specific Lymphocytes in Infants Using Single-Cell Microtools Margaret Feeney, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Innate NKT Cells in HIV Infection Division of Experimental Medicine
Plasmodium Parasites, Plasmids, and Other Reagents Division of Experimental Medicine
HIV-Specific T Cell Responses in Rectal Mucosa Elizabeth Sinclair, PhD Division of Experimental Medicine
Human Immune System Layering and the Neonatal Response to Vaccines Mike McCune, MD, PhD Division of Experimental Medicine
Design of an Effective Vaccine against HIV: An Alternative Hypothesis Mike McCune, MD, PhD Division of Experimental Medicine
Interruption of Maternal-Fetal Transmission of HIV Mike McCune, MD, PhD Division of Experimental Medicine
Exchange of samples- Placental Biopsies Mike McCune, MD, PhD Division of Experimental Medicine
Studies of Ocular Complications of AIDS (SOCA) Division of Experimental Medicine
Recent Thymic Emigrants of the CD4 T-Cell Lineage Mike McCune, MD, PhD Division of Experimental Medicine
A Novel Myeloid Subset Mediating Tolerance to Malaria Division of Experimental Medicine
An Ultrasensitive in Vivo Latent HIV Viral Outgrowth Assay Using Humanized Mice Division of Experimental Medicine, AIDS Research Institute
Effector and Regulatory T Cell Responses and Protection from Clinical Malaria Margaret Feeney, MD IGHS Faculty Affiliate, Division of Experimental Medicine
Molecular Effects of Mind-Body Intervention on GC Sensitivity and Immune Function Division of Experimental Medicine
Heat Shock Protein 90 and HIV Persistence Division of Experimental Medicine
Interferon-independent mechanisms of malaria restriction by helper T cells Mike McCune, MD, PhD IGHS Faculty Affiliate, Division of Experimental Medicine, AIDS Research Institute
Bay Area Hepatitis C Cooperative Research Center Mike McCune, MD, PhD Division of Experimental Medicine
Trefoil Factors Regulate Th2 Immunity Division of Experimental Medicine
The Impact of Tolerance in the Newborn on Lentiviral Infection Mike McCune, MD, PhD Division of Experimental Medicine
Plasmodium Parasites, Plasmids, and Other Reagents Division of Experimental Medicine
Novel flow cytometry-based assay for HIV-infected cells Mike McCune, MD, PhD Division of Experimental Medicine
Impact of Sirolimus (Rapamycin) on HIV-1 Persistence and Immune Function Division of Experimental Medicine, AIDS Research Institute
Investigating the Impact of In Utero HIV or Malaria Exposure on CD4+ T Cell Development Center for AIDS Research (CFAR), Division of Experimental Medicine, AIDS Research Institute
HIV-Specific T-Cell Responses in Rectal Mucosa Elizabeth Sinclair, PhD Division of Experimental Medicine
DARE: Delaney AIDS Research Enterprise to Find a Cure Steven Deeks, MD Division of Experimental Medicine, AIDS Research Institute
Defining critical events in early HIV infection-effects of alcohol and early ART Mike McCune, MD, PhD IGHS Faculty Affiliate, Division of Experimental Medicine, AIDS Research Institute
Layering of the Human Immune System, Viral Infections, and Childhood Asthma Mike McCune, MD, PhD Division of Experimental Medicine
A Novel Microfluidic HIV-1 Co-Culture Assay to Quantify Latent Reservoirs Division of Experimental Medicine, AIDS Research Institute
The UW Asthma and Allergic Diseases Cooperative Research Center Mike McCune, MD, PhD Division of Experimental Medicine
Role of Monocyte Oxidative Stress and Mineralocorticoid Receptor Signaling on Cardiovascular Disease and Persistent Inflammation in Antiretroviral-Treated HIV+ Persons Division of Experimental Medicine, AIDS Research Institute
Early Antiretroviral Therapy and HIV Remission in Perinatal Infection Mike McCune, MD, PhD Division of Experimental Medicine, AIDS Research Institute