Diabetes Center

This Center is also allied with the national Immune Tolerance Network.

Active Projects: 15

Project Investigator All Organizations Start date End date
Randomized Controlled Trial of the Effect of the Livongo Health Diabetes Management Program vs. Standard Care on Glycemic Control Jeffrey E. Olgin, MD Division of Cardiology, Diabetes Center
Class of 2014 Pew Latin American Fellows Program in the Biomedical Sciences Diabetes Center
Genetic models for exRNA communication Thomas M. McManus, PhD Diabetes Center
Antigen Specificity of Regulatory T cells in Type 1 diabetes T1D Jeffrey A. Bluestone, PhD Diabetes Center
Epigenetic Regulation of Pancreatic Cancer Matthias Hebrok, PhD Diabetes Center
Developing eTACs as a novel method of tolerance in Type 1 Diabetes Mark S. Anderson, MD, PhD Diabetes Center
The Melanocortin-4 Receptor in Human Obesity Christian Vaisse, MD, PhD Diabetes Center
Colon Organoid Investigation of KRAS-Dependent Synthetic Lethality Thomas M. McManus, PhD Diabetes Center
Collaborative MS Research Center Award- Systematic Genome Editing of the Risk Variants in Multiple Sclerosis Alexander Marson, MD, PhD Diabetes Center
Obesity in ciliopathies: How neuronal primary cilia control appetite Christian Vaisse, MD, PhD Diabetes Center
Using human stem cell-derived thymic epithelium to remodel T1D immune tolerance Mark S. Anderson, MD, PhD Diabetes Center
UCSF Nutrition Obesity Research Center Christian Vaisse, MD, PhD Diabetes Center
The role of Spry2 in beta cell function and the unfolded protein response Gregory M. Ku, MD, PhD Diabetes Center
Diabetes, Endocrinology & Metabolism Training Grant Michael S. German, MD Division of Endocrinology, Diabetes Center
Thymic medullary epithelial cell turnover and control of immune tolerance Mark S. Anderson, MD, PhD Diabetes Center

Archived Projects: 36

Project Investigator All Organizations Start date End date
B7/CD18/CTLA-4 Costimulation in the Pathogenesis of R-EAE Jeffrey A. Bluestone, PhD Diabetes Center
UCSF Comprehensive Center for Immunologic Diseases (CCID) Jeffrey A. Bluestone, PhD Diabetes Center
Immunomodulation of Transplant Rejection by Anti-CD3 mAb Jeffrey A. Bluestone, PhD Diabetes Center
Phase II Double Blinded, Placebo-Controlled, Efficacy and Safety Evaluation of Allergen Immunotherapy Co-Administered with Omalizumab, an Anti-IgE mAb Jeffrey A. Bluestone, PhD Diabetes Center
Use of CHIP-CHIP Technology to Identify Target Genes for Foxp3 Regulatory T Cells Jeffrey A. Bluestone, PhD Diabetes Center
Role of Notch 1 in Immunie Tolerance Jeffrey A. Bluestone, PhD Diabetes Center
Spontaneous Autoimmune Model of Peripheral Neuropathy Jeffrey A. Bluestone, PhD Diabetes Center
Coolscope Digital Microscope and Virtual Slide Software Suite Jeffrey A. Bluestone, PhD Diabetes Center
CD101 DC Subsets in T1D Jeffrey A. Bluestone, PhD Diabetes Center
Immunomodulation of Transplant Rejection by Anti-CD3 mAb Jeffrey A. Bluestone, PhD Diabetes Center
Aire-Deficiency as a Novel Model of Uveitis Mark S. Anderson, MD, PhD Diabetes Center
A Randomized, Double Blind, Placebo Controlled, Multicenter Study to Evaluate the Efficacy &Safety of Atorvastatin in Patients w/ Clinically Isolated Syndrome & High Risk for Conversion to M.S. Jeffrey A. Bluestone, PhD Diabetes Center
Spontaneous Autoimmune Model of Peripheral Neuropathy Jeffrey A. Bluestone, PhD Diabetes Center
Exploiting Normal “cMyc” Biology for Human Beta Cell Expansion Matthias Hebrok, PhD Diabetes Center
Brehm Coalition - Type 1 Diabetes Research Jeffrey A. Bluestone, PhD Diabetes Center
ADA Mentor Based Postdoctoral Fellowship Training Matthias Hebrok, PhD Diabetes Center
Exploiting Normal cMyc Biology for Human Beta Expansion Matthias Hebrok, PhD Diabetes Center
Effects of Hedhehog Signaling on Pancreas Organogenesis Matthias Hebrok, PhD Diabetes Center
Site-Directed Gene Modification in Human Pluripotent Stem Cells Matthias Hebrok, PhD Diabetes Center
Safety & Efficacy of Abatacept in Adults with Relapsing-Remitting Multiple Sclerosis Jeffrey A. Bluestone, PhD Diabetes Center
Development of Regulatory T-Cells for Treatment of Autoimmune Disease Jeffrey A. Bluestone, PhD Diabetes Center
Stem Cell differentiation to thymic epithelium for inducing immune tolerance to stem cells Mark S. Anderson, MD, PhD Diabetes Center
nPOD Coordinating Center Mark S. Anderson, MD, PhD Diabetes Center
Collaborative Network for Clinical Research on Immune Tolerance - Offcampus Portion Jeffrey A. Bluestone, PhD Diabetes Center
Collaborative Network for Clinical Research on Immune Tolerance Jeffrey A. Bluestone, PhD Diabetes Center
Expanding Beta-Cell Mass Michael S. German, MD Diabetes Center
Mentor-based Postdoctoral Fellowship in Islet Biology Michael S. German, MD Diabetes Center
Embryonic signaling pathways in pancreatic cancer Matthias Hebrok, PhD Diabetes Center
Role of Innate Lymphoid Cells in Autoimmunity Jeffrey A. Bluestone, PhD Diabetes Center
Identification and Functional Characaterization of SIM1 Obesity-Associated Variants Christian Vaisse, MD, PhD Diabetes Center
Mechanisms of beta cell maturation Matthias Hebrok, PhD Diabetes Center
The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation Jeffrey A. Bluestone, PhD Diabetes Center
Thymic Medullary Epithelial Cell Turnover and Control of Immune Tolerance Mark S. Anderson, MD, PhD Diabetes Center
Stem cell derived human thymus for the study of APS1 Mark S. Anderson, MD, PhD Diabetes Center
Role of innate immune system on Treg programming in human autoimmune disease Jeffrey A. Bluestone, PhD Diabetes Center
Generation of a Functional Thymus from Human Stem Cells for the Induction and Maintenance of Immune Tolerance to Stem Cells Derivatives Mark S. Anderson, MD, PhD Diabetes Center