Department of Neurology

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Active Projects: 24

Project Investigator All Organizations Start date End date
Dopamine receptor trafficking in drug sensitization and behavioral flexibility Jennifer Whistler, PhD Department of Neurology
Cerebrovascular mechanisms of HIV-associated cognitive impairment in China Felicia Chow, MD IGHS Faculty Affiliate, Department of Neurology
TLC-Pre-gPrd: Tracking Longitudinal Change in Presymptomatic genetic Prion Disease Michael Geschwind, MD, PhD Memory and Aging Center
U.S. Army Medical Research Acquisition Activity (USAMRAA) Victor Valcour, MD, PhD Memory and Aging Center
Leadership and Operations Center, AIDS Clinical Trials Group Felicia Chow, MD Department of Neurology
Pharmacokinetics and tolerability of adjunctive linezolid for the treatment of tuberculous meningitis Felicia Chow, MD IGHS Faculty Affiliate, Department of Neurology
A Multicenter, Multinational, Randomized, Double Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Laquinimod (0.5, 1.0 and 1.5 mg/day) as Treatment in Patients with Huntington's Disease Michael Geschwind, MD, PhD Memory and Aging Center
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical Trajectories Memory and Aging Center
Epidemiology of stroke Anthony Kim, MD IGHS Faculty Affiliate, Department of Neurology, Cardiovascular Research Institute (CVRI)
Global Brain Health Institute Victor Valcour, MD, PhD Memory and Aging Center
Interventions for Symptom Management in Older Patients with HAND Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center, AIDS Research Institute
Global Teleneurology Service Riley Bove, MD IGHS Faculty Affiliate, Department of Neurology
A Randomized, Double-Blind, Placebo-Controlled, SingleAscending Dose Study to Assess the Safety, Tolerability,and Pharmacokinetics of C2N-8E12 in Subjects withProgressive Supranuclear Palsy Adam Boxer, MD, PhD Memory and Aging Center
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center, AIDS Research Institute
Effect of Passive Immunization on the Progression of Mild Alzheimer's Disease: Solanezumab(LY2062430) versus Placebo Adam Boxer, MD, PhD Memory and Aging Center
The Four Repeat Tauopathy Neuroimaging Initiative Adam Boxer, MD, PhD Memory and Aging Center
A Randomized Controlled Trial of Vitamin D Supplementation in Multiple Sclerosis Department of Neurology
Neuropathological changes underlying clinical heterogeneity in Alzheimer disease Memory and Aging Center
Defining the clinical utility of CSF biomarkers of neurodegeneration in HIV+ elders Memory and Aging Center
Next-Generation Diagnostics for Acute Encephalitis Michael Wilson, MD IGHS Faculty Affiliate, Department of Neurology
Machine learning to distinguish HAND from Alzheimer's disease in HIV over age 60 Victor Valcour, MD, PhD Memory and Aging Center
Phase III multicenter multicenter, randomized, double-blind, placebo controlled, parallel group efficacy and safety study of Crenezumbab in patients with propromal to mild Alzheimers disease Adam Boxer, MD, PhD Memory and Aging Center
ENROLL-HD -A Prospective Registry Study in a Global Huntington's Disease Cohort Michael Geschwind, MD, PhD Memory and Aging Center
Redefining Tuberculosis Meningitis with Metagenomics and Host Transciptomics Michael Wilson, MD IGHS Faculty Affiliate, Immunogenetics Laboratory

Archived Projects: 129

Project Investigator All Organizations Start date End date
California Acute Stroke Prototype Registry (CASPR) / Development of Prototypes for the Paul Coverdell National Acute Stroke Registry Neurocritical Care and Stroke Research
Warfarin Versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Study Department of Neurology
The Impact and Performance of NINDS-Sponsored Clinical Trials Neurocritical Care and Stroke Research
Optimizing Management of Transient Ischemic Attacks Department of Neurology
CASTIA Neurological Core Imaging Lab (NCIL) Neurocritical Care and Stroke Research
Antiplatelet Therapy for Ischemic Stroke and Transient Ischemic Attack in U.S. Community Hospitals Department of Neurology
California Non-AD Diagnostic Reliability Consortium Julene Johnson, PhD Memory and Aging Center
Quality Improvement in Stroke Prevention (QUISP) Neurocritical Care and Stroke Research
NSA Guidelines Neurocritical Care and Stroke Research
Central Nervous System Events in Primary HIV Infection Department of Neurology
Development and Validation of a Diagnostic Tool for HIV Dementia Department of Neurology
Cognitive Health and Brain Vulnerability in Aging Insulin Resistant Patients Victor Valcour, MD, PhD Memory and Aging Center
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia Department of Neurology
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia Department of Neurology
The role of infection in childhood stroke Heather Fullerton, MD Neurocritical Care and Stroke Research
CNS Immune / Inflammatory Biomarkers in HIV Controllers Richard Price, MD Department of Neurology
MAPS: Matrix And Platinum Science, A Prospective, Randomized, Multicenter, Trial Investigating Matrix2 tm and GDC? Coils for the treatment of intracranial saccular aneurysms Trial Neurocritical Care and Stroke Research
Tracheostomy with Invasive Ventilation for Patients with Amyotrophic Lateral Sclerosis in Japan and USA: Comparative Study ALS Center
HIV Neurocognitive Disorders: A Randomized Clinical Trial of CNS-Targeted HAART Department of Neurology
The Neuropathobiology of Primary HIV-1 Infection Richard Price, MD Department of Neurology
HIV Proteomics Center for Host Viral Response Characterization Richard Price, MD Department of Neurology
Dementia in HIV Patients over 60 Years of Age Victor Valcour, MD, PhD Memory and Aging Center
Expanded Access to MGAWN1 in Subjects with Suspected West Nile Neuroinvasive Disease; Substantial Exposure, or Infection and a Compromised Immune System Jeffrey Ralph, MD Department of Neurology
Point: Platelet-Oriented Inhibition in New TIA Neurocritical Care and Stroke Research
Neuroform Angiographic Analysis (Subset of MAPS study data) Neurocritical Care and Stroke Research
DNA of Thai Male Thyrotoxic Patients and Family Members Louis Ptacek, MD Department of Neurology
Central Nervous System Effects in Acute HIV Seroconversion Victor Valcour, MD, PhD Memory and Aging Center
Pediatric Data Coordinating and Analysis Center Department of Neurology
Clinical Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis (ALS) Department of Neurology
Targeted Treatment of Early Cryptococcal Infection in HIV-infected Patients Department of Neurology
Early Diagnosis of Human Prion Disease Michael Geschwind, MD, PhD Memory and Aging Center
HIV and Global Drug Therapies: Peripheral Neuropathy Complications and Mechanisms Victor Valcour, MD, PhD Memory and Aging Center
HIV-1 Specific Immune Responses in Thai Individuals with HIV Dementia Victor Valcour, MD, PhD Memory and Aging Center
Treatment of HIV-Associated Cognitive Impairment Department of Neurology
Salt intake and pediatric MS susceptibility Department of Neurology
Neuroprotection with Riluzole in Patients with Early Multiple Sclerosis (MS) Department of Neurology
Clinical and MRI features of NMO spectrum disorders in children Department of Neurology
Defective Forebrain Development in Mutant Mice Department of Neurology
Patient Management in Pediatric Onset Multiple Sclerosis (MS) Department of Neurology
MYCN and Medulloblastoma Department of Neurology
Stimulants and Childhood Stroke: a Population-Based Nested Case-Control Study Nancy Hills, PhD IGHS Faculty Affiliate, Neurocritical Care and Stroke Research
Biomarker Optimization for Progranulin Trials (The BOPT Study) Adam Boxer, MD, PhD Memory and Aging Center
New Approaches to Dementia Heterogeneity Memory and Aging Center
Task Order #5: Bio-Protect Study - Neurological Emergencies Treatment Trials Network Department of Neurology
Biodiversity surveys in Indonesia and discovery of health and energy solutions Jennifer Whistler, PhD Department of Neurology
Supplement: Biodiversity Surveys in Indonesia and Discovery of Health and Energy Solutions Jennifer Whistler, PhD Department of Neurology
Targeting the translational apparatus in MYCN-driven medulloblastoma Department of Neurology
Multiple Sclerosis International Federation Mcdonald Fellowship Department of Neurology
Neurobiological Predictors of Huntington's Disease (Predict-HD) Michael Geschwind, MD, PhD Memory and Aging Center
Epi4K: Gene discovery in 4,000 Epilepsy Genomes (4/7) Elliott Sherr, MD, PhD Department of Neurology
BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects with Mild Alzheimer's Disease Adam Boxer, MD, PhD Memory and Aging Center
Orexins and the Trigeminovascular System Department of Neurology
Defining CNS HIV Infection and Its Effects in Treated Patients: Foundation for Eradication Richard Price, MD Department of Neurology
The Pathobiology of Primary HIV-1 Infection Richard Price, MD Department of Neurology
Neurobiological Changes in Network Function and Amyloid Deposition in Alzheimer Disease Memory and Aging Center
Peripheral Reservoir of HIV Monocytes Pivotal to Cognition in HIV Victor Valcour, MD, PhD Memory and Aging Center
Whole Genome Sequencing in Multiple Sclerosis Immunogenetics Laboratory
Eye Movement Control in Normal Elderly and MCI Adam Boxer, MD, PhD Memory and Aging Center
Development of Resting-State FMRI As a Biomarker for Alzheimer Disease Memory and Aging Center
Predicting epilepsy after traumatic brain injury in children and young adults: A population based study Heather Fullerton, MD Department of Neurology
International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) Richard Price, MD Department of Neurology
Task Order #3: Protect II Study - Neurological Emergencies Treatment Trial Department of Neurology
An Open Label Dose Finding Study of Nimodipine for the Treatment of Frontotemporal Dementia Due to Progranulin Insufficiency From GRN Gene Mutations Adam Boxer, MD, PhD Memory and Aging Center
Prevention of Stroke after STOP Heather Fullerton, MD Neurocritical Care and Stroke Research
National Alzheimer's Coordinating Center, NACC Memory and Aging Center
Multimodal Imaging of Antibody-Mediated Therapy for Japanese Encephalitis Virus Michael Wilson, MD Department of Neurology
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Sequential Cohort, Dose-Ranging Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TPI-287 in Patients with Mild to Moderate Alzheimer's Disease Adam Boxer, MD, PhD Memory and Aging Center
Cross-Sectional Examination of Cerebrospinal Fluid Kinetic Biomarkers of Axonal Transport for Amyotrophic Lateral Sclerosis (Als) Diagnosis and Progression Richard Price, MD Department of Neurology
Amitriptyline and Topiramate in the Prevention of Childhood Migraine Department of Neurology
A feasibility study of the transcranial Doppler breath-holding challenge to evaluate cerebral vasoreactivity in HIV-infected individuals in China Felicia Chow, MD IGHS Faculty Affiliate, Department of Neurology
Non-Invasive Neurostimulation of the Vagus Nerve with the Gammacore Device for the Prevention of Chronic Migraine Department of Neurology
Phase III Clinical Trial "Platelet Oriented Inhibition in New Tia" - Drug: Plavix Neurocritical Care and Stroke Research
Multi-Locus Sequence Typing Environmental Fungal Samples from Western Kenya Department of Neurology
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of LY2951742 in Patients with Migraine Department of Neurology
Neurodevelopment and Imaging among HIV-infected Children from the PREDICT Study Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center
The Translational Alzheimer Disease Research Program Memory and Aging Center
New Combination Therapies for Early Cryptococcal Infection in HIV Infected Individuals: A Randomized Controlled Trial Department of Neurology
Cellular and Genetic Basis of Anaplastic Medulloblastoma Department of Neurology
Infantile Spasms: Clinical and Genetic Predictors of Outcomes and Therapeutic Insights Elliott Sherr, MD, PhD IGHS Faculty Affiliate, Department of Neurology
Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression Department of Neurology
Four Repeat Tauopathy Neuroimaging Initiative Adam Boxer, MD, PhD Memory and Aging Center
Characterization of Familial Advanced Sleep Phase Syndrome Louis Ptacek, MD Department of Neurology
SOCRATES - Acute Stroke Or Transient Ischaemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes Department of Neurology
Pediatric Data Coordinating and Analysis Center Department of Neurology
Distinct Embryonic Origin for Postnatal Dentate Neural Stem Cells Department of Neurology
Samples from Brazilian Aging Brain Study Group Memory and Aging Center
VIPS: Vascular Effects of Infection in Pediatric Stroke Heather Fullerton, MD Neurocritical Care and Stroke Research
Phase II Study to Evaluate the Efficacy and Safety of MABT5102A in Patients with Mild to Moderate Alzheimer's Diseases Adam Boxer, MD, PhD Memory and Aging Center
Treatment Adherence in Pediatric Multiple Sclerosis: Project 5982896 Department of Neurology
The Amyotrophic Lateral Sclerosis (ALS)/Parkinsonism-Dementia Complex of Guam: Exploring the Mechanism of a Rare Tauopathy Michael Geschwind, MD, PhD Memory and Aging Center
Extension of Phase II Studies ABE4869g and ABE4955g in Patients with Mild to Moderate Alzheimer Disease Adam Boxer, MD, PhD Memory and Aging Center
Phase I Multiple Ascending Dose Trial of the MT Stabilizer TPI-287 for Alzheimer Disease (AD) Adam Boxer, MD, PhD Memory and Aging Center
Environmental and genetic risk factors for pediatric multiple sclerosis Department of Neurology
Burden, Depression, and Health in Dementia Caregivers: the Role of Emotion Memory and Aging Center
Genetic network analysis of cancer targets Department of Neurology
Frontotemporal Dementia: Genes, Images, and Emotions Memory and Aging Center
HIV Tropism, Persistence, Inflammation, and Neurocognition in Therapy Initiation Richard Price, MD Department of Neurology
SF-NETT: San Francisco Neurological Emergencies Trials Network Department of Neurology
Long-Term Central Nervous System (CNS) Consequences of Treatment during Acute Infection Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center
Creating Maps of 4D Brain Images to Unravel Dementia Heterogeneity of Aging HIV Population Victor Valcour, MD, PhD IGHS Faculty Affiliate, Department of Neurology
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Memory and Aging Center
Murine Neuroblastoma Models for Preclinical Therapeutics Department of Neurology
The Efficacy of Intrathecal Baclofen for Spasticity in Primary Lateral Sclerosis Department of Neurology
The Coagulation Cascade as a Biomarker and Therapeutic Target for Progressive Multiple Sclerosis Department of Neurology
Fingolimod Administered Orally Once Daily vs Interferon Beta-1a i.m. Once Weekly in Pediatric Patients with Multiple Sclerosis Department of Neurology
A Novel Cognitive Brain Computer Interface (cBCI) for Attention Deficit Disorder Jyoti Mishra, PhD IGHS Faculty Affiliate, Department of Neurology
Point: Platelet-Oriented Inhibition in New Transient Ischemic Attack (TIA) and Minor Ischemic Stroke Neurocritical Care and Stroke Research
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center
Predicting Stroke after Trauma (PSAT) Heather Fullerton, MD Neurocritical Care and Stroke Research
Multidisciplinary NeuroAIDS Research Training to Improve HIV Outcomes in Nigeria Felicia Chow, MD IGHS Faculty Affiliate, Department of Neurology
ALS Center of Excellence at UCSF Department of Neurology
Genetic and molecular pathophysiology of ATS Louis Ptacek, MD Department of Neurology
Microbiomes in Pediatric MS Department of Neurology
Therapeutic Interventions during Acute Infection to Address the CNS Reservoir for HIV Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center
Metabolic changes underlying the association of high fat diet and low vegetable intake with the risk of MS relapse Department of Neurology
Predicting Progression of Human Prion Disease Michael Geschwind, MD, PhD Memory and Aging Center
Selectively targeting delta opioid receptor subtypes to control drinking behavior Jennifer Whistler, PhD Department of Neurology
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases Michael Geschwind, MD, PhD Memory and Aging Center
Determinants of Resilience on Youth with HIV Infection and Youth Affected by HIV Victor Valcour, MD, PhD IGHS Faculty Affiliate, Memory and Aging Center
Transthyretin-Associated Amyloidoses Outcomes Survey (THAOS) (Survey ID: Fx-R-001) Jeffrey Ralph, MD Department of Neurology
Genetic Variation in the Neuropeptide S Receptor and Opioid Abuse Liability Jennifer Whistler, PhD Department of Neurology
Patient-family views on pediatric MS research needs, outcomes, and Department of Neurology
Causes, treatment and prevention of corticobasal degeneration Adam Boxer, MD, PhD Memory and Aging Center
A Double-Blind, Placebo-Controlled, Randomized, Parallel Group, 12-Month Safety and Efficacy Trial of Leuco-methylthioninium bis(hydromethanesulfonate) in Subjects with Behavioral Variant Frontotemporal Dementia (bvFTD) Adam Boxer, MD, PhD Memory and Aging Center
Developing low-cost cognitive tools for dementia assessment in low-to-middle income countries (LMICs) Memory and Aging Center
Predicting progression of human prion disease Michael Geschwind, MD, PhD Memory and Aging Center
Population genetic analysis and regional variation Kicheol Kim, PhD Department of Neurology
MYCN, mTOR and translation control in medulloblastoma Department of Neurology
The Frontotemporal Lobar Degeneration Clinical Research Consortium Adam Boxer, MD, PhD Memory and Aging Center