Drug and Diagnostics Development

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Active Projects: 161

Project Investigator All Topics Start date
End date
Vest Prevention of Early Sudden Death Trial/Prediction of ICD Therapies Jeffrey E. Olgin, MD Drug and Diagnostics Development, Newborn and Infant Health
Developing an breast FNA biopsy service in Trujillo Peru Ronald Balassanian, MD Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Optimization of health care expenditures to maximize societal value Dhruv Kazi, MD, MSc, MS Cardiovascular Disease, Drug and Diagnostics Development, Health Economics and Policy
Identification of Signaling Pathways Associated with Lyme Disease Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
UCSF-GIVI Center for AIDS Research (CFAR) Paul A. Volberding, MD HIV/AIDS, Tuberculosis, Malaria, Cancer/Oncology, Cardiovascular Disease, Drug and Diagnostics Development, Immunology, Pharmacology and Drug Treatment, Neurology and Mental Health, Trauma and PTSD, Women's Health, Pediatrics, Implementation and Behavioral Science, Training and Capacity Building, Training International Scholars and Clinicians
HARC Center: HIV Accessory and Regulatory Complexes Alan D. Frankel, PhD Zoonosis, Emerging Disease, and Drug Resistance, HIV/AIDS, Immunology
Clinical Trial of the Infuse/Mastergraft Delayed Healing Device with Rigid Internal Fixation in the Treatment of Tibial Delayed Healing ("Tibia Study") Saam Morshed, MD, MPH, PhD Surgery and Anesthesia, Drug and Diagnostics Development
Oxygen Sensors and P450 Monooxygenases in Mycobacertium tuberculosis Paul R. Ortiz De Montellano, PhD Tuberculosis, Immunology
Center for RNA Systems Biology Jonathan S. Weissman, PhD Immunology, Genetics, Pharmacology and Drug Treatment
Novel approaches to identify host genes required for Chlamydia pathogenesis Joanne N. Engel, MD, PhD Infectious Disease, Sexually Transmitted Infections (STIs), Drug and Diagnostics Development
Cytoskeletal Regulation of T cell Motility and Synaptic Signaling Matthew F. Krummel, PhD Immunology, Epidemiology and Surveillance
Pilot Study of Symptom Relief in Patients with Medial Knee Osteoarthritis (OA) Treated with the Kinespring® Knee Implant for Load Reduction C. Benjamin Ma, MD Surgery and Anesthesia, Drug and Diagnostics Development
Improve the Cho Expression of a ScFv Fragment by Optimizing the DNA Sequence of the ingle chain variable fragment ScFv and/or Leader Sequence James D. Marks, MD, PhD Drug and Diagnostics Development, Immunology
Phase 1b Study of SAR650984 in Combo with Lenalidomide and Dexa for Treatment of Relapsed or Refractory Multiple Myeloma Thomas G. Martin, MD Cancer/Oncology, Drug and Diagnostics Development, Pharmacology and Drug Treatment
A Randomized, Double Blinded, Active-Controlled Study of Cb-183,315 in Patients with Clostridium-difficile-Associated Diarrhea Sarah B. Doernberg, MD Infectious Disease, Drug and Diagnostics Development
Career: Massively-Parallel Single-Cell Genomics and Transcriptomics with Droplet Microfluidics Adam Abate, PhD Drug and Diagnostics Development
Randomized, Double-Blind, Phase II Trial of Vitamin D Supplementation in Participants with Previously Untreated Metastatic Colorectal Cancer Katherine Van Loon Steitz, MD, MPH Cancer/Oncology, Drug and Diagnostics Development
Protocol M12-999: Safety and Efficacy of the Combination of ABT-450/ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 Coadministered with Ribavirin (RBV) in Adult Liver Transplant Recipients with Genotype 1 Hepatitis C Virus (HCV) Infection Norah A. Terrault, MD Drug and Diagnostics Development
Molecular Methods for Cervical Cancer Screening in HIV+ Women Nancy Hessol, MSPH Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Three Arm Phase II Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC) Alan P. Venook, MD Cancer/Oncology, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Chemical Methods for Ferrous Iron Dependent Drug Delivery Adam R. Renslo, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
HINT: HIV Immune Networks Team Modeling Core Nevan J. Krogan, PhD, MSc HIV/AIDS, Immunology
Evolution and Inhibition of Serine Beta-Lactamase Activity Adam R. Renslo, PhD Opportunistic Infection, Drug and Diagnostics Development
Testing Targeted Therapy in Philadelphia Chromosome-Like (Ph-Like) All Mignon Loh, MD Cancer/Oncology, Drug and Diagnostics Development
Enhancing Control of HIV by Inhibiting TRAIL Steven G. Deeks, MD HIV/AIDS, Drug and Diagnostics Development, Immunology
Molecular and Cellular Mechanisms of Synaptic Growth Genetics
Randomized, Double-Blind, Placebo-Controlled, Multicenter, Clinical Study Evaluating the Impact of Serum-Derived Bovine Immunoglobulin Protein Isolate, a Medical Food, on Nutritional Status in HIV+ Subjects with HIV-Associated Enteropathy Ma Somsouk, MD, MAS Immunology, Pharmacology and Drug Treatment
Probing Tumor Metastasis through Chemical Cell Surface Engineering Valerie M. Weaver, PhD Cancer/Oncology, Immunology
Molecular basis of tissue interactions that regulate craniofacial development Ralph S. Marcucio, PhD Genetics
Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming Jonathan S. Weissman, PhD Genetics
Gene regulation and function in early embryos Thomas B. Kornberg, PhD Genetics
Structural Basis of Protease-Activated Receptor Function Shaun R. Coughlin, MD, PhD HIV/AIDS, Drug and Diagnostics Development
The Genetics of Glaucoma in African Americans Neil J. Risch, PhD Eye Disease and Blindness, Genetics
Integrated Training in Reproductive Sciences Synthia Mellon, PhD Sexually Transmitted Infections (STIs), Genetics, Family Planning, Residencies, Fellowships, and Postdoctoral Training
Impact of Low IL-10 Levels at Birth and Leukemia Risk Joseph Wiemels, PhD Cancer/Oncology, Immunology
Antigen Decoding by T cells Orion D. Weiner, PhD Immunology
Affinity-Directed Tagging of Protein Binding Partners in Signaling James Wells, PhD Immunology
Viral metagenomics to discover viruses Eric L. Delwart, PhD Drug and Diagnostics Development
Immunology & epidemiology of intestinal infectious diseases Robert Owen, MD Zoonosis, Emerging Disease, and Drug Resistance, Immunology, Epidemiology and Surveillance
Nursing education in malarial settings Kimberly Baltzell, RN, PhD, MS Malaria, Drug and Diagnostics Development, Implementation and Behavioral Science, Engagement in Care, Training and Capacity Building, Training International Scholars and Clinicians, Patient and Peer Education
UCSF- Kenyan radiology residency training William P. Dillon, MD Drug and Diagnostics Development, Training and Capacity Building, Training International Scholars and Clinicians
Biomedical simulation models describing how molecular level events effect changes in phenotype Anthony C. Hunt, PhD Immunology, Genetics
Trefoil Factor Proteins Modulate Host Immunity against Hookworms Zoonosis, Emerging Disease, and Drug Resistance, Immunology
A Phase Ib Dose Escalation Trial of Carfilzomib plus Bendamustine and Rituximab in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma Charalambos (Babis) Andreadis, MD Cancer/Oncology, Drug and Diagnostics Development
Nanoscale Devices for Targeted Delivery of Combination Therapies Shawn M. Douglas, PhD Drug and Diagnostics Development
Richer Models of Asthma Risk: Bridging the Environment-Genetics Divide Noah A. Zaitlen, PhD Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics
Massively Parallel Identification of Causative 3´ UTR Variants in Asthma David J. Erle, MD Chronic Respiratory Disease, Genetics
A Pharmacogenomics Study of HIV Latency: The Role of Anti-Programmed Cell Death-1 (PD-1) Signaling Sulggi A. Lee, MD HIV/AIDS, Immunology
Microbial Pathogenesis and Host Defense Joanne N. Engel, MD, PhD Immunology, Residencies, Fellowships, and Postdoctoral Training
Structural and Functional Studies of HER Receptor Tyrosine Kinases Natalia Z. Jura, PhD Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Physical and Genetic Interaction Landscape of the Tyrosine Kinome Nevan J. Krogan, PhD, MSc Cancer/Oncology, Diabetes, Immunology
Racial/Ethnic and Socioeconomic Disparities in Biologic and Clinical Systemic Lupus Erythematosus (SLE) Outcomes Maria Dall'Era, MD Immunology, Access or Barriers to Care, Stigma and Discrimination
The Genetic Basis of Pediatric Cholestasis Laura N. Bull, PhD Genetics, Newborn and Infant Health
Integrative Program in Complex Biological System (ipCBS) Joseph L. Derisi, PhD Drug and Diagnostics Development, Immunology, Genetics, Residencies, Fellowships, and Postdoctoral Training
Molecular Genetics of Liver Cancers Xin Chen, PhD Cancer/Oncology, Genetics
Mechanisms of nanostructure-enhanced transepithelial drug delivery Tejal A. Desai, PhD Drug and Diagnostics Development
Microfluidic immunoprofiling for biomarker discovery in rheumatoid arthritis Adam Abate, PhD Immunology
Macular Edema Treatment Trials Associated with MUST (META-MUST) Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development
Functional Manipulation of Memory Regulatory T cells in Skin Cancer/Oncology, Immunology
Macular Edema Treatment Trials Associated with MUST (META-MUST) Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development
Inner City Asthma consortium 3 (ICAC3) Susan Lynch, PhD Immunology
Validation of Existing Ultra-Sensitive Assays for Quantifying HIV Persistence Steven G. Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse Children Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics, Pediatrics
International Network for Strategic Initiatives in Global HIV Trials (INSIGHT): START Steven G. Deeks, MD HIV/AIDS, Drug and Diagnostics Development
Impact of interferon-alpha inhibition on immune function and viral persistence in HIV disease Steven G. Deeks, MD HIV/AIDS, Immunology
New ways of treating pancreatic cancer based on reversing K-Ras-mediated stemness Frank McCormick, PhD, FRS Cancer/Oncology, Immunology
Regulation of Innate Immune Signaling by Lyn Kinase Clifford A. Lowell, MD, PhD Immunology
UZ-UCSF CTU Spilhaus Clinical Research Site HPTN 076 2nd Protocol Funding Zvavahera Chirenje, MD, FRCOG Infectious Disease, HIV/AIDS, Drug and Diagnostics Development, Women's Health, Training International Scholars and Clinicians, Patient and Peer Education
Immune Tolerance Network - OPTIMAL Sandy Feng, MD, PhD Surgery and Anesthesia, Immunology
Ubiquitin and Psoriasis Averil I. Ma, MD Immunology
Timing of ART and homeostasis of the persistent HIV reservoir in the adult J. Michael McCune, MD, PhD HIV/AIDS, Immunology
Identifying Human Breast Carcinogens Using Exposomics Laura Fejerman, PhD Occupational and Environmental Disease, Drug and Diagnostics Development
Microfluidic PCR Method to Identify and Characterize HIV-Infected Single Cells Timothy J. Henrich, MD HIV/AIDS, Drug and Diagnostics Development
Programming Long Term Durable HIV-1 Specific T cell Responses Steven G. Deeks, MD HIV/AIDS, Immunology
ACC: Callosal Agenesis as a Window into Common Neurodevelopment Disorders Elliott H. Sherr, MD, PhD Genetics, Neurology and Mental Health, Dementia and Cognitive Impairment
Targeting BET-bromodomains in neuroblastoma William Weiss, MD, PhD Cancer/Oncology, Drug and Diagnostics Development, Pediatrics
Building an Implantable Artificial Kidney Shuvo Roy, PhD Drug and Diagnostics Development
p24 Antigen and Alternative Markers in Infants, Vietnam Annette H. Sohn, MD HIV/AIDS, Drug and Diagnostics Development, Newborn and Infant Health
Novel methods for monitoring long-term drug exposure and resistance amplification during treatment of multidrug resistant tuberculosis John J. Metcalfe, MD Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development
Gene linkage study of multiple sclerosis sibling pairs Stephen L. Hauser, MD Genetics, Neurology and Mental Health
Towards detailed and consistent function prediction from protein family databases Patricia C. Babbitt, PhD Genetics
Hepatic degradation of cytochrome P450 enzymes Maria A. Correia, PhD Drug and Diagnostics Development
Pharmacogenomics of Microtubule Targeting Agents Deanna L. Kroetz, PhD Cancer/Oncology, Drug and Diagnostics Development
Multicenter Osteoarthritis Study (MOST) Second Renewal Michael C. Nevitt, PhD Immunology, Aging
A Randomized, Double-Blind, Placebo-Controlled, SingleAscending Dose Study to Assess the Safety, Tolerability,and Pharmacokinetics of C2N-8E12 in Subjects withProgressive Supranuclear Palsy Adam L. Boxer, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health
A point of care assay for chlamydia to assure prompt treatment in at risk minorities Julius Schachter, PhD Infectious Disease, Eye Disease and Blindness, Drug and Diagnostics Development
Intervascular Capsule for Islet Transplantation in Type I Diabetic Patients Shuvo Roy, PhD Diabetes, Drug and Diagnostics Development
A Technological Platform for the Identification of Serine Proteases in Cancer Charles S. Craik, PhD Cancer/Oncology, Drug and Diagnostics Development
1 of 7 Epi4K: Gene discovery in 4,000 epilepsy genomes - Administrative Core Daniel H. Lowenstein, MD Genetics, Neurology and Mental Health
Elucidating mechanisms of tolerance to commensal skin bacteria Immunology
A Program of Research in Population Cytogenetics Tracey Woodruff, PhD, MPH Occupational and Environmental Disease, Genetics, Newborn and Infant Health
Allosteric Inhibition of a Family of Proteolytic Enzymes Charles S. Craik, PhD Immunology, Pharmacology and Drug Treatment
Elimination of Instrumental Bias for Quantitative Diffusion Imaging in Clinical Oncology Trials David Newitt, PhD Cancer/Oncology, Drug and Diagnostics Development
Optogenetic dissection of the growth and activation network in T cells Immunology
Innate immune regulation of stem cells in bone formation Immunology, Pediatrics
The impact of TB co-infection on the reservoir of persistent HIV in vivo J. Michael McCune, MD, PhD HIV/AIDS, Tuberculosis, Immunology
Pfizer Protocol Number B3451002: A PHASE 2b, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF STAPHYLOCOCCUS AUREUS 4-ANTIGEN VACCINE (SA4Ag) IN ADULTS UNDERGOING ELECTIVE POSTERIOR INSTRUMENTED LUMBAR SPINAL Drug and Diagnostics Development
A Phase 3, Placebo-Controlled, Randomized, Double-Blind, Multi- Center Study of LJPC-501 in Patients with Catecholamine-Resistant Hypotension (CRH) Drug and Diagnostics Development
Phase 2, Parallel-Arm Study of MGCD265 in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Activating Genetic Alterations in Mesenchymal-Epithelial Transition Factor Cancer/Oncology, Genetics, Pharmacology and Drug Treatment
Host-Directed Strategies to Create Synergistic Antibacterial Therapies Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development, Immunology
Allosteric Regulation in the KDM5 Family of Histone Demethylases Fujimori Danica Galonic, PhD Immunology
Impact of Chemotherapy and Stem Cell Transplant on HIV-1 Reservoir Dynamics Timothy J. Henrich, MD HIV/AIDS, Drug and Diagnostics Development
BRASL - A rapid Barcoded RNA Annealing, Selection, and Ligation assay to detect pathogens. Eric D. Chow, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
A Technological Platform for the Identification of Serine Proteases in Cancer Charles S. Craik, PhD Cancer/Oncology, Drug and Diagnostics Development
Translational development of a novel antibody-drug conjugates against myeloma Bin Liu, PhD Cancer/Oncology, Immunology
Validation of candidate ASD genes by targeted sequencing with molecular inversion probes Genetics, Neurology and Mental Health
Antigen Specificity of Regulatory T cells in Type 1 diabetes T1D Jeffrey A. Bluestone, PhD Diabetes, Immunology
QB3 Entrepreneurship Programs Regis B. Kelly, MD Drug and Diagnostics Development
Genomic research on the African diaspora Ian Whitmarsh, PhD Genetics
Cytoskeletal Regulation of T cell Motility and Synaptic Signaling Matthew F. Krummel, PhD Immunology
Interventional Study to Assess the Safety and Efficacy of Pharmaceutical Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Dravet Syndrome Drug and Diagnostics Development, Neurology and Mental Health
Study to Assess the Long-term Safety of Pharmaceutical Cannabidiol Oral Solution as an Adjunctive Treatment for Pediatric and Adult Subjects With a Treatment-resistant Seizure Disorder Who Complete INS011-14-029, INS011-14-024, or INS011-14-25 Drug and Diagnostics Development, Neurology and Mental Health, Pediatrics
INS011-14-029: A Phase 1/2 study to assess the pharmacokinetics and safety of multiple doses of pharmaceutical Cannabidiol Oral Solution in pediatric subjects with treatment-resistant seizure disorders Drug and Diagnostics Development, Neurology and Mental Health, Pediatrics
Targeting MYC-Driven Cell Cycle Progression in Neuroendocrine Prostate Cancer with Gallium Citrate PET as a Novel Biomarker of MYC Transcriptional Activity Rahul R. Aggarwal, MD Cancer/Oncology, Drug and Diagnostics Development
HVTN 703/HPTN 081 Protocol Funding (PF) Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health
A Phase 2, In-Home, Safety and Efficacy Evaluation of Episodic Administration of Open-Label Palovarotene in Subjects with Fibrodysplasia Ossificans Progressiva (FOP) Drug and Diagnostics Development, Immunology
Mother-child genetic contributions to autoimmunity Lindsey A. Criswell, MD, MPH Immunology
The cell and molecular mechanisms underlying CD28 costimulation Arthur Weiss, MD, PhD Immunology
GS-US-334-1113: A Phase 4, a Long Term Follow-up Registry for Adolescent and Pediatric Subjects Who Received a Gilead Hepatitis C Virus Diret Acting Antiviral (DAA) in Gilead- Sponsored Chronic Hepatitis C Infection Trial Philip Rosenthal, MD Drug and Diagnostics Development
Metagenomic Contributions to Type 2 Diabetes Among Filipino Populations Mark Seielstad, PhD Diabetes, Genetics
amfAR Institute for HIV Cure Research Paul A. Volberding, MD HIV/AIDS, Drug and Diagnostics Development
Observational Study of Pediatric Rheumatic Disease: The CARRA Registry Emily Von Scheven, MD Immunology, Pediatrics
Innate Immune Mechanisms of Primary Graft Dysfunction after Lung Transplantation Mark R. Looney, MD Infectious Disease, Immunology
The gut microbiome: an unexpected contributor to cancer drug resistance Peter J. Turnbaugh, PhD Cancer/Oncology, Immunology, Pharmacology and Drug Treatment
SIngle-saMPLE tuberculosis evaluation to facilitate linkage to care: The SIMPLE TB trial Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Plastic States Associated with Cellular Stress and Malignancy: Insights for Prevention and Treatment of Lethal Metaplastic Cancers Thea D. Tlsty, PhD Cancer/Oncology, Immunology
CC# 159518 A Phase I, First-Time-in-Human Study of MEDI9197, a TLR 7/8 Agonist, Administered Intratumorally in Subjects with a Solid Tumor Cancer Pamela N. Munster, MD Cancer/Oncology, Drug and Diagnostics Development
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases Michael D. Geschwind, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
TB Surrogate Markers for Assessing Response to Treatment (TB SMART Study) Payam Nahid, MD, MPH Tuberculosis, Drug and Diagnostics Development
Impact of Cannabis on Inflammation and Viral Persistence in Treated HIV/SIV Peter W. Hunt, MD HIV/AIDS, Immunology
UCSF Team, The genetic, epigenetic, and immunological underpinnings of cancer evolution through treatment Steven J. Altschuler, PhD Cancer/Oncology, Genetics
HPTN 082 - Protocol Implementation Funding Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development
CC 152512: A Phase II, Single Arm, Multicenter Trial to Determine the Efficacy and Safety of CTL019 in Adult Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) Charalambos (Babis) Andreadis, MD Drug and Diagnostics Development
Novel serologic assays of P. falciparum exposure for improved surveillance in control and elimination. R01 resubmision Bryan R. Greenhouse, MD Malaria, Drug and Diagnostics Development, Epidemiology and Surveillance
747-303: A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of beticholic Acid in Subjects with Nonalcoholic Steatohepatitis Mandana Khalili, MD Immunology
Effector and regulatory T cell responses and protection from clinical malaria Margaret E. Feeney, MD Malaria, Drug and Diagnostics Development, Immunology
Improving the molecular diagnosis of drug resistant tuberculosis Midori Kato-Maeda, MD Tuberculosis, Drug and Diagnostics Development
A Phase 3 Evaluation of Daclatasvir and Sofosbuvir with Ribavirin in Cirrhotic Subjects with Genotype 3 Chronic Hepatitis C Infection Norah A. Terrault, MD Infectious Disease, Drug and Diagnostics Development
747-303: A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multi-center Study evaluating the Safety and Efficacy of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis. Muhammad Y. Sheikh, MD Drug and Diagnostics Development
Genes, air pollution, and asthma severity in minority children Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Genetics
Phase 1, Open-Label, Dose-Escalation, Safety and Tolerability Study of INCB054329 in Subjects With Advanced Malignancies Pamela N. Munster, MD Cancer/Oncology, Drug and Diagnostics Development
Gilead Sciences Research Scholars Program in Cystic Fibrosis. Oren S. Rosenberg, MD, PhD Immunology
An Open Label, Randomized Phase 2 Trial of Prostvac and Ipilimumab as Monotherapy or in Combination for Men with Localized Prostate Cancer Undergoing Radical Prostatectomy Lawrence Fong, MD Drug and Diagnostics Development
Functional Testing of Host Genes that control HIV Latency in Primary Immune Cells Alexander Marson, MD, PhD HIV/AIDS, Immunology
Fine-tuning the Neutrophilic Response to Pneumonia Mark R. Looney, MD Immunology
A Phase 1b (Open-Label) / Phase 2 (Randomized, Double-Blinded) Study Evaluating Gemcitabine and Docetaxel with or without Olaratumab in the Treatment of Advanced Soft Tissue Sarcoma Cancer/Oncology, Drug and Diagnostics Development
A Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of ABT-493/ABT-530 in Adult Post-Liver or Post-Renal Transplant Recipients with Chronic Hepatitis C Virus Genotype 1 - 6 Infection (MAGELLAN-2) Norah A. Terrault, MD Infectious Disease, Drug and Diagnostics Development
UCSF Pediatric Rheumatology Fellowship Erica F. Lawson, MD Immunology, Residencies, Fellowships, and Postdoctoral Training
Using human stem cell-derived thymic epithelium to remodel T1D immune tolerance Mark S. Anderson, MD, PhD Immunology
Taking It to the Next Level: Measuring and Modeling Effects of Inter-Individual Protein-Level Buffering on Phenotypic Penetrance of DNA Copy Number Variants Genetics
BSL3 upgrading for Live-attenuated poliovirus testing Raul Andino-Pavlovsky, PhD Infectious Disease, Immunology
A feasibility study evaluating a reservoir storage system for continuous oxygen delivery in Uganda Melissa Morgan, MD, MSc, PhD Drug and Diagnostics Development, Newborn and Infant Health
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect Jeffrey N. Martin, MD, MPH HIV/AIDS, Cancer/Oncology, Drug and Diagnostics Development
Sustained Strengthening of Public Health Laboratory, Transfusion Services and Health Care Worker Infection Control Practices for Ebola Virus Disease in Liberia Kayla Enriquez, MD, MPH Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development, International Health Policy, Systematic Reviews and Guideline Development, Health Systems Strengthening, Training International Scholars and Clinicians
Selective AAK1 and GAK inhibitors for combating Dengue and other emerging viral infections Raul Andino-Pavlovsky, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Tel-Me-Box: Validating and testing a novel, low-cost, real-time monitoring device with hair level analysis among adherence-challenged patients Maria L. Ekstrand, PhD HIV/AIDS, Drug and Diagnostics Development, Treatment Adherence
RAPID-VL: Optimizing HIV Viral Load Monitoring and Outcomes for High-Risk Populations Vivek Jain, MD HIV/AIDS, Drug and Diagnostics Development
Novel Therapeutics for Treatment of River Blindness and Lymphatic Filariasis Judy A. Sakanari, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
UC Valley Fever Research Initiative Anita Sil, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Genetics
Snakebite treatment in Nepal Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Antimalarial drugs in Ugandan populations Melissa Conrad, PhD HIV/AIDS, Malaria, Drug and Diagnostics Development, Pharmacology and Drug Treatment, Pediatrics

Active Projects: 414

Project Investigator All Topics Start date
End date
Regulation of Human Thymic Function in Vivo J. Michael McCune, MD, PhD Immunology
Cohort Study of Patients Receiving Long-Term Combination Therapy [II] Jeffrey N. Martin, MD, MPH HIV/AIDS, Drug and Diagnostics Development
NK and T-Cell Costimulation by NKG2D/DAP10 Lewis L. Lanier, PhD Noncommunicable and/or Chronic Disease, Immunology
Development of Falcipain Inhibitors as Antimalarial Drugs Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Herpesviral Gene Expression in Kaposi's Sarcoma Donald E. Ganem, MD HIV/AIDS, Cancer/Oncology, Genetics
The Genetic Epidemiology of RA and SLE Lindsey A. Criswell, MD, MPH Noncommunicable and/or Chronic Disease, Genetics, Epidemiology and Surveillance, UCSF Professional Education, Patient and Peer Education
Collaborative Network for Clinical Research on Immune Tolerance - Offcampus Portion Jeffrey A. Bluestone, PhD Diabetes, Immunology
Collaborative Network for Clinical Research on Immune Tolerance Jeffrey A. Bluestone, PhD Diabetes, Immunology
Use of r-hGh to Enhance Thymopoiesis and to Facilitate Immune Restoration in Individuals Infected with HIV-1 J. Michael McCune, MD, PhD HIV/AIDS, Immunology
Double-Stranded RNA Virus in Giardia Ching C. Wang, MD Genetics
Diagnostic Imaging Core Laboratory Services: Ischemic Stroke Neuroflow Study, Vasospasm Subjects William P. Dillon, MD Drug and Diagnostics Development
Vaccine to Prevent HIV Infection in Pregnancy and Newborns Raul Andino-Pavlovsky, PhD HIV/AIDS, Drug and Diagnostics Development, Newborn and Infant Health
Structural Biology and Targeted Drug Design for AIDS Paul R. Ortiz De Montellano, PhD HIV/AIDS, Drug and Diagnostics Development
T Regulatory Cells and T Cell Activation in HIV Disease Steven G. Deeks, MD HIV/AIDS, Immunology
Development and Testing of New Medications for the Treatment of Emerging Infectious Diseases [I] Philip J. Rosenthal, MD Infectious Disease, Drug and Diagnostics Development
Novel Anti-Malarials by Combinatorial Pharmacogenomics Joseph L. Derisi, PhD Infectious Disease, Malaria, Drug and Diagnostics Development
RAE-1 Family of Proteins in Innate and Adaptive Immunity Lewis L. Lanier, PhD Immunology
Phase II Double Blinded, Placebo-Controlled, Efficacy and Safety Evaluation of Allergen Immunotherapy Co-Administered with Omalizumab, an Anti-IgE mAb Jeffrey A. Bluestone, PhD Immunology
Selective Destruction of Cytochrome P450 by Drugs Paul R. Ortiz De Montellano, PhD Drug and Diagnostics Development
Host Protein Degradation by Schistosome Parasites Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Genetic Risk Factors for Pneumonia in SLE Lindsey A. Criswell, MD, MPH Noncommunicable and/or Chronic Disease, Genetics
EBV BMRF-2 Protein in Infection of Oral Epithelial Cells Sharof Tugizov, PhD Noncommunicable and/or Chronic Disease, Drug and Diagnostics Development
Examination of genome instability in Plasmodium Falciparum using functional genomics Malaria, Genetics
Sensitivity of Electronic Alcohol Diagnosis Constance M. Weisner, DrPH Drug and Diagnostics Development
Creating Polyketide Antibiotic Diversity by Engineering Cytochrome P450 Enzymes / UC Discovery Paul R. Ortiz De Montellano, PhD Immunology
Identification of the CD8+Cell Anti-HIV Factor (CAF) Jay A. Levy, MD HIV/AIDS, Immunology
UCSF Comprehensive Center for Immunologic Diseases (CCID) Jeffrey A. Bluestone, PhD Immunology
T Regulatory Cells in HIV Infection Frederick M. Hecht, MD HIV/AIDS, Immunology
Novel Tetracyclines as Antimalarial Agents Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Novel Tetracyclines as Antimalarial Agents Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Immunogenetic Studies of Autoimmune Disease Lindsey A. Criswell, MD, MPH Immunology
Targeting Cysteine Proteases--Antiparasitic Chemotherapy Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Population Genetic Mapping of Tourette Syndrome Victor I. Reus, MD Genetics, Neurology and Mental Health
CORE B: Intracellular Pathogens and Innate Immunity Joseph L. Derisi, PhD Tuberculosis, Immunology
International Fellowship Program in Drug Development Kathleen M. Giacomini, PhD Drug and Diagnostics Development, Training and Capacity Building, Residencies, Fellowships, and Postdoctoral Training
Valley Fever Vaccine Project George W. Rutherford, MD Zoonosis, Emerging Disease, and Drug Resistance, Opportunistic Infection, Occupational and Environmental Disease, Drug and Diagnostics Development
Novel Strategies for defining the Role of HLA in SLE Lindsey A. Criswell, MD, MPH Noncommunicable and/or Chronic Disease, Genetics
Multicenter Uveitis Steroid Treatment (MUST) Trial Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development
Admixture Mapping Development and Testing in African American SLE Lindsey A. Criswell, MD, MPH Genetics
Neurosteroids in Health and Disease Synthia Mellon, PhD Genetics, Neurology and Mental Health
Clinical Pharmacology, Drug Action and Pharmacogenetics Neal L. Benowitz, MD Drug and Diagnostics Development, Pharmacology and Drug Treatment
3D-FSE-zeta equipment William P. Dillon, MD Drug and Diagnostics Development
HIV Vaccine Trials Network - Laboratory Personnel Support Teri Liegler, PhD Immunology
Case-Control Association Studies and Genetic Confounding Esteban G. Burchard, MD, MPH Genetics, Risk Reduction and Prevention
Development of Regulatory T-Cells for Treatment of Autoimmune Disease Jeffrey A. Bluestone, PhD Immunology, Pharmacology and Drug Treatment
Utility of Rapid Diagnostic Tests for Malaria Heidi A. Hopkins, PhD Malaria, Drug and Diagnostics Development, Pediatrics
High Throughput Assay for Screening Compounds Against T. Brucei Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
Optimization of Cysteine Protease Inhibitors Targeting Trypanosoma Brucei Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
RNAi as an Intercellular Antiviral Defense Mechanism Raul Andino-Pavlovsky, PhD Infectious Disease, Genetics
NK Cell Receptors and Their Ligands Lewis L. Lanier, PhD Immunology, Genetics
Dissecting the HLA Contribution to Rheumatoid Arthritis Lindsey A. Criswell, MD, MPH Genetics
Valganciclovir to Reduce T Cell Activation in HIV Infection Peter W. Hunt, MD HIV/AIDS, Drug and Diagnostics Development, Immunology
Phase 2, Multi-Center, Randomized, Double-Blinded, Placebo-Controlled Study to Assess Safety and Immunogenicity of Two Doses of 3?-aminomethylnicotine-P. aeruginosa r Exoprotein A Conjugate Vaccine (NicVAX?) in 2 Different Dosing Schedules in Smokers Victor I. Reus, MD Drug and Diagnostics Development, Smoking and Tobacco
Secretion of Virulence Factors by Mycobacterium tuberculosis Infectious Disease, HIV/AIDS, Tuberculosis, Genetics
HIV Controllers: A Potential Model for HIV Eradication Steven G. Deeks, MD HIV/AIDS, Immunology
HIV Entry Inhibitors: A New Therapeutic Option Steven G. Deeks, MD HIV/AIDS, Immunology
Chemoprophylaxis and HIV-Host Interactions [II] Douglas Nixon, MD, PhD HIV/AIDS, Immunology
Transcriptional Responses of Parasite and Host during Intestinal Colonization and Invasion by Entamoeba histolytica Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Pharmacology and Drug Treatment
International Network for Strategic Initiatives in Global HIV Trials/ ICR INSIGHT Steven G. Deeks, MD HIV/AIDS, Drug and Diagnostics Development
The Epilepsy Phenome/ Genome Project (EPGP) [I] Daniel H. Lowenstein, MD Genetics
Genetic Diversity as a Determinant of Viral Pathogenesis and Attenuation Raul Andino-Pavlovsky, PhD Infectious Disease, Genetics, Risk Reduction and Prevention
Bipolar Endophenotypes in Population Isolates Victor I. Reus, MD Genetics, Neurology and Mental Health
The Biology of HIV Transmission Frederick M. Hecht, MD HIV/AIDS, Drug and Diagnostics Development
Pharmacogenomics of Antimalarial Drugs Sunil Parikh, MD, MPH Malaria, Genetics, Pharmacology and Drug Treatment
Genetics of Schizophrenia in Oceanic Palau William F. Byerley, MD Genetics, Neurology and Mental Health, Pediatrics
Trypanosome Drug Development Consortium Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Effectiveness of QuantiFERON-TB Gold (QFT-G) in Contact Tracing Elizabeth Fair, PhD, MPH Tuberculosis, Drug and Diagnostics Development
UCSF-FIND Uganda Project Laurence Huang, MD Tuberculosis, Drug and Diagnostics Development
Elite Controllers Steven G. Deeks, MD HIV/AIDS, Immunology, Genetics
Viruses in Breast Fluid: Biomarkers for Breast Cancer? Kimberly Baltzell, RN, PhD, MS Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Genetic Analysis of the Nucleosome and RNA Polymerase II: a Systems Approach Nevan J. Krogan, PhD, MSc Noncommunicable and/or Chronic Disease, Cancer/Oncology, Genetics
Raltegravir Intensification in Antiretroviral-Treated Patients Exhibiting a Suboptimal CD4+T Cell Response Steven G. Deeks, MD HIV/AIDS, Immunology
Translation Regulation in Giardia lamblia Ching C. Wang, MD Infectious Disease, Genetics
Whole Genome Analyses for Asthma in Latino Populations Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Occupational and Environmental Disease, Genetics
Deferasirox (Exjade)-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) Peter Chin-Hong, MD Opportunistic Infection, Drug and Diagnostics Development
Examination of the Protective Effect of Pet Ownership on Asthma Development Through Bacterial Community Analysis of Household Dust and Infant Stool Susan Lynch, PhD Occupational and Environmental Disease, Immunology
Oral Wash for Nucleic Acid Diagnosis and Prognosis of TB in HIV-infected Ugandans J. Luke Davis, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development
Initiation of Allergic Immunity by Parasites Richard M. Locksley, MD Immunology
Early Detection of Metastasis-Prone Breast Cancers Laura J. Esserman, MD Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Project 2: Effect of Humanized Anti Pcrv Antibody on Total Bacterial Community Composition of Adult Patients with Ventilator-Associated Pneumonia Susan Lynch, PhD Immunology
Probing Below the Surface: Development of a Molecular Diagnostic Assay to Detect Emergent Viral Escape Variants Teri Liegler, PhD HIV/AIDS, Drug and Diagnostics Development
Metagenomics for Detection and Discovery of Viruses Associated with Acute Gastroenteritis in Mexico Charles Y. Chiu, MD, PhD Drug and Diagnostics Development
Early Diagnosis of Human Prion Disease Michael D. Geschwind, MD, PhD Infectious Disease, Drug and Diagnostics Development
Virus Detection Using Microarrays and Characterization of a Novel Cardiovirus Charles Y. Chiu, MD, PhD Drug and Diagnostics Development
Immunological Targeting of APOBEC Proteins to Cure HIV Infection Douglas Nixon, MD, PhD HIV/AIDS, Immunology
Molecular Engineering of Erythrotropic Bacteria for Treatment and Prevention of Human Malaria Joseph L. Derisi, PhD Malaria, Drug and Diagnostics Development
Establishing a Core Facility for Virus Detection and Discovery Charles Y. Chiu, MD, PhD Drug and Diagnostics Development, Epidemiology and Surveillance
B Cells in Central Nervous System (CNS) Autoimmunity Scott Zamvil, MD, PhD Noncommunicable and/or Chronic Disease, Immunology
Prostate Cancer Therapeutic Clinical Investigation "First in Man" Eric J. Small, MD Cancer/Oncology, Drug and Diagnostics Development
Ultra-Low Viral Detection Using the Abbott RealTime HIV-1 Assay Teri Liegler, PhD HIV/AIDS, Drug and Diagnostics Development
Pfizer International Growth Study (KIGS) - Protocol TRN 87-052-45 (CCID A6281276) Stephen M. Rosenthal, MD Drug and Diagnostics Development
Transthyretin-Associated Amyloidoses Outcomes Survey (THAOS) (Survey ID: Fx-R-001) Jeffrey W. Ralph, MD Genetics, Neurology and Mental Health
Replication fidelity mutants as attenuated poliovirus seeds for IPV production Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development, Pharmacology and Drug Treatment
Characterization of Regulatory Elements Leading to Human Limb Malformations Nadav Ahituv, PhD Noncommunicable and/or Chronic Disease, Genetics
Treating HIV-Infected Elite Controllers as a Model of HIV Remission Hiroyu Hatano, MD, MHS HIV/AIDS, Immunology
Immunodiagnosis of Active Tuberculosis in HIV-Infected Patients Adithya Cattamanchi, MD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development
Sputum Processing Methods J. Luke Davis, MD Tuberculosis, Drug and Diagnostics Development
Molecular Genetics of Liver Cancers Xin Chen, PhD Cancer/Oncology, Genetics
Innate Effector Function and HIV-1 Control Steven G. Deeks, MD HIV/AIDS, Immunology
Metagenomics for Identification of Infectious Triggers of KLS Charles Y. Chiu, MD, PhD Drug and Diagnostics Development
Microbicide Pregnancy Registry--Microbicide Trials Network Juan E. Vargas, MD Sexually Transmitted Infections (STIs), HIV/AIDS, Drug and Diagnostics Development, Women's Health, Family Planning
Core B: Intracellular Pathogens and Innate Immunity Joseph L. Derisi, PhD Zoonosis, Emerging Disease, and Drug Resistance, Immunology
Regulation of Genomic Instability in Early Breast Cancer Thea D. Tlsty, PhD Cancer/Oncology, Immunology
Chemicals with Potential Activity against Malaria Parasites Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Preventing and Curing Persistent Infections with Transient FTY/720 Treatment Mary F. Premenko-Lanier, PhD HIV/AIDS, Noncommunicable and/or Chronic Disease, Immunology
Rhbmp2 vs. AutograpH for Critical Size Tibial Defects: a Multi-Center Randomized Trial Amir M. Matityahu, MD Surgery and Anesthesia, Drug and Diagnostics Development
Develop Clinical Evidence of Substantial Equivalence to Predicate Devices Suellen Miller, PhD, CNM, MHA Drug and Diagnostics Development
Testing novel adjuvants to enhance mucosal immunity elicited by inactivated poliovirus vaccine (IPV) Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development, Immunology
Genomics of Lupus: Refining the complex HLA association with SLE across ethnic and phenotype subgroups Lindsey A. Criswell, MD, MPH Immunology
UCSF/Ragon Collaboration on HIV "Elite" Controllers Steven G. Deeks, MD HIV/AIDS, Drug and Diagnostics Development, Immunology, Genetics
Preserving Renal Function and Protective Immunity Via Anti-LFA1-Based CNI Avoidance Peter G. Stock, MD, PhD Immunology
CNS Immune / Inflammatory Biomarkers in HIV Controllers Richard W. Price, MD HIV/AIDS, Immunology
Computational and Functional Annotation of the Zebrafish Genome Regulatory Toolbox Nadav Ahituv, PhD Genetics
Nanoscale Science and Engineering Center (NSEC) Tejal A. Desai, PhD Drug and Diagnostics Development
Subcontract Work in Association with LLNL LDRD Project: COMP-08ERD036 Raul Andino-Pavlovsky, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
HIV Incidence Testing in Hair Christopher D. Pilcher, MD HIV/AIDS, Drug and Diagnostics Development, Treatment Adherence
Task Order Agreement No. CRB-DCR01-S-09-00325 Diane V. Havlir, MD Drug and Diagnostics Development
Identification of the CD8+ Cell Anti-HIV Factor (CAF) Jay A. Levy, MD HIV/AIDS, Immunology
Valley Fever Vaccine Project 2010 George W. Rutherford, MD Zoonosis, Emerging Disease, and Drug Resistance, Opportunistic Infection, Occupational and Environmental Disease, Drug and Diagnostics Development
Solitaire With the Intention For Thrombectomy (SWIFT) Study William P. Dillon, MD Drug and Diagnostics Development
Recent Thymic Emigrants of the CD4 T-Cell Lineage J. Michael McCune, MD, PhD Immunology
Nanoporous Capsules for the Investigation of Macroencapsulation Parameters Tejal A. Desai, PhD Diabetes, Drug and Diagnostics Development
Siglec-F and Resolution of Allergic Inflammation Homer A. Boushey, MD Immunology, Genetics
Mesalamine to Reduce T Cell Activation in HIV Infection Peter W. Hunt, MD HIV/AIDS, Drug and Diagnostics Development
Risk of Leukemia after Protracted Exposures to Low Doses of Ionizing Radiation. Lydia Zablotska, MD, MPA, PhD Noncommunicable and/or Chronic Disease, Cancer/Oncology, Genetics, Epidemiology and Surveillance, Risk Reduction and Prevention
An Automated High Throughput Phenotypic Screen for Schistosomiasis Drug Discovery Conor R. Caffrey, PhD Infectious Disease, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Interferon-Gamma Release Assays for the Diagnosis of Tuberculosis in Adults Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Microbicide Pregnancy Registry-Microbicide Trials Network Juan E. Vargas, MD Sexually Transmitted Infections (STIs), HIV/AIDS, Drug and Diagnostics Development, Women's Health
Mechansims of poliovirus replication Raul Andino-Pavlovsky, PhD Infectious Disease, Noncommunicable and/or Chronic Disease, Genetics
Identifying Intermediate Phenotypes for Compulsive Hoarding Carol A. Mathews, MD Genetics, Neurology and Mental Health
Inflammatory and Clinical Consequences of Low-Level Viremia in HIV-1 Infected Patients Hiroyu Hatano, MD, MHS HIV/AIDS, Immunology
Dissecting the HLA contribution to Rheumatoid Arthritis Lindsey A. Criswell, MD, MPH Genetics
Discovering Drugs for Prion Diseases Stanley B. Prusiner, MD Drug and Diagnostics Development
Comprehensive Diagnostics for Viral Encephalitis/Meningitis Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Comprehensive Diagnostics for Viral Encephalitis/Meningitis Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
The NYSGRC: A Large Scale Center for PSI:Biology Andrej Sali, PhD Drug and Diagnostics Development
Epigenetic Profiling of Multiple Cell and Tissue Types in Sjögren's Syndrome Lindsey A. Criswell, MD, MPH Genetics
Lead Identification to Clinical Candidate Selection: Drugs for Chagas' Disease Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
PAAR4Kids-Pharmacogenomics Research Network Mignon Loh, MD Cancer/Oncology, Genetics, Pharmacology and Drug Treatment
The Role of Continuous Phenotypic Variation in Structural Defects of the Face Ralph S. Marcucio, PhD Genetics, Newborn and Infant Health
DSC09r-178688 GEH Novel MR Technology (7T & C13) Sarah Nelson, PhD Drug and Diagnostics Development
A Rapid Pan-Viral Microarray Diagnostic for Category A-C Biodefense Pathogens Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Global Innate Immune Responses to HIV-1 Infection Nevan J. Krogan, PhD, MSc HIV/AIDS, Immunology
Ubiquitylation and the Regulation of Immune Homeostasis Averil I. Ma, MD Immunology
Developing a Macrofilaricidal Drug for Onchocerciasis Using Anacor's Novel Oxaborole Technology Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Single Molecule DNA Mapping for DNA and CNV Analysis Pui-Yan Kwok, MD, PhD Genetics
An Evolutionary-Developmental Approach to Stem Cells Using Teeth As a Model Ophir Klein, MD, PhD Oral Health, Genetics, Training International Scholars and Clinicians
Dissecting Epistasis and Pleiotropy in Autism Towards Personalized Medicine Lauren A. Weiss, PhD Genetics, Risk Reduction and Prevention
Stem Cell differentiation to thymic epithelium for inducing immune tolerance to stem cells Mark S. Anderson, MD, PhD Immunology
Iron-Dependent Drug Delivery as a New Paradigm in Anti-Parasitic Chemotherapy and Prophylaxis Adam R. Renslo, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Identification of Viruses in an Asthma Cohort Charles Y. Chiu, MD, PhD Chronic Respiratory Disease, Drug and Diagnostics Development
HLA-A Low Resolution Typing Surgery and Anesthesia, Immunology
Core Laboratory for Sputum Quality Assurance and Sputum Analysis John V. Fahy, MD Noncommunicable and/or Chronic Disease, Chronic Respiratory Disease, Drug and Diagnostics Development
Identification of Novel Therapeutics Molecules against Old and New World Cutaneous Leishmaniasis Adam R. Renslo, PhD Drug and Diagnostics Development
K777 for the Treatment of Chagas' Disease, IND-enabling Studies and IND Submission Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Genetic Studies of Cortex Structure and Development John L. Rubenstein, MD, PhD Genetics, Neurology and Mental Health
Preventing Fucose-Dependent Binding of Aspergillus and Pseudomonas to Lung Mucin John V. Fahy, MD Infectious Disease, Chronic Respiratory Disease, Genetics
Evaluation of a Novel Automated PCR Method for Infectious Disease Diagnostics Steven A. Miller, MD, PhD Drug and Diagnostics Development
Characterizing the Role of Immune Activation in HIV Persistence Steven G. Deeks, MD HIV/AIDS, Immunology
Broad Detection of Infectious Agents in Blood by Microarrays and Deep Sequencing Charles Y. Chiu, MD, PhD Infectious Disease, Drug and Diagnostics Development
Comprehensive Assay Platform and Database for Drug Transporter Interaction Studies Kathleen M. Giacomini, PhD Drug and Diagnostics Development
Schistosome Research Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Point-of-Care Diagnostics for STI and UTI Julius Schachter, PhD Drug and Diagnostics Development
Viral Discovery in Human and Animal Samples Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Immunomodulation of transplant rejection by anti-CD3 mAb Jeffrey A. Bluestone, PhD Immunology
Whole Blood/Serum Samples from Patients with Hepatitis Charles Y. Chiu, MD, PhD Infectious Disease, Drug and Diagnostics Development
Structure-Aided Design of CYP51 Inhibitors for Treatment of Parasitic Infections Larissa Podust, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
A New Field Assay to Diagnose and Monitor Schistosomiasis Conor R. Caffrey, PhD Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Cytokine Signaling in Neurons: Inflammation, Pain and Pruritis Martin Steinhoff, MD, PhD Immunology
UCSF/UCB Joint Graduate Group in Bioengineering Tejal A. Desai, PhD Drug and Diagnostics Development, Residencies, Fellowships, and Postdoctoral Training
Mechanism, Specificity, and Inhibition of Cytochrome P450 Paul R. Ortiz De Montellano, PhD Drug and Diagnostics Development, UCSF Professional Education
Synthetic Biology Engineering Research Center (SynBERC) Wendell A. Lim, PhD Drug and Diagnostics Development, Genetics, Pharmacology and Drug Treatment
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Katherine L. Possin, PhD Drug and Diagnostics Development, Dementia and Cognitive Impairment
Protein homeostasis mechanisms underlying enterovirus replication and evolution Raul Andino-Pavlovsky, PhD Genetics
Origami Female Condom User-Preference (FUP) Study Karen S. Smith-McCune, MD, PhD Drug and Diagnostics Development, Women's Health, Family Planning
Integrating computation and genetics to quantify specificity in protein networks Nevan J. Krogan, PhD, MSc Genetics
Genomic Analysis in Narcolepsy-Cataplexy Neil J. Risch, PhD Genetics, Neurology and Mental Health
Tissue Biopsy Samples from Head and Neck Cancers Charles Y. Chiu, MD, PhD Cancer/Oncology, Drug and Diagnostics Development
Phase 1 Iontophoretic Delivery of Dexamethasone for Tx of Anterior Scleritis Nisha Acharya, MD Eye Disease and Blindness, Drug and Diagnostics Development, Pharmacology and Drug Treatment
GEAR-Genetics and the Environment Associated with Male Reproduction Laurence S. Baskin, MD Occupational and Environmental Disease, Genetics
Nanoporous Films for Ocular Drug Delivery Tejal A. Desai, PhD Eye Disease and Blindness, Drug and Diagnostics Development
MiRNAs as prognostic markers for prostate cancer patients on active surveillance Robert H. Blelloch, MD, PhD Cancer/Oncology, Drug and Diagnostics Development
MR Metabolic Imaging of Response to Targeted Therapies in GBM Sabrina M. Ronen, PhD Cancer/Oncology, Drug and Diagnostics Development
Biomarkers for PTSD in Female Iraq and Afghanistan Veterans Owen Wolkowitz, MD Drug and Diagnostics Development, Trauma and PTSD
Genome wide association study of breast cancer subtype and survival in Latinas Laura Fejerman, PhD Cancer/Oncology, Genetics, Epidemiology and Surveillance
Recombinant Antibody Network James Wells, PhD Drug and Diagnostics Development
Epi4K: Gene Discovery in 4,000 Epilepsy Genomes (1/7) Daniel H. Lowenstein, MD Genetics
Epi4K: Gene discovery in 4,000 Epilepsy Genomes (4/7) Elliott H. Sherr, MD, PhD Cardiovascular Disease, Genetics
Novel Technologies to Increase the Accessibility and Accuracy of Tuberculosis Diagnostic Services in Hanoi Province, Vietnam Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
End-to-End Technology Validation of a Miniaturized, Automated Instrument for In Situ Measurement of Microbial Gene Expression in Space Michael R Wilson, MD Drug and Diagnostics Development
Multiplexed Viral and Cytokine Response Assays Using NanoString Technology Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Whole Genome Sequencing of Multiplex Schizophrenia Pedigrees from an Isolated Population William F. Byerley, MD Genetics, Neurology and Mental Health
Postnatal Serum IGF-1 Levels, Growth and Retinopathy of Prematurity in Latin-American Infants Alejandra G. De Alba Campomanes, MD, MPH Eye Disease and Blindness, Drug and Diagnostics Development, Pediatrics
The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation Jeffrey A. Bluestone, PhD Immunology
Development of Human mAbs to Target Cardiomyocytes and Cardiac Fibroblasts Cardiovascular Disease, Immunology
Neuroform Angiographic Analysis (Subset of MAPS study data) Cardiovascular Disease, Drug and Diagnostics Development
RNA Interference and High-Content Image Analysis to Discover New Drug Targets to Treat the Tropical Disease Schistosomiasis Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Development of Neuroprotective Molecule for the Treatment of Atophic Age-Related Macular Degeneration Matthew M. Lavail, PhD Eye Disease and Blindness, Immunology
Dual Energy X-Ray Absorptiometry (DXA) Scan Analysis and Quality Control Review for NHANES 2011-2016 John A. Shepherd, PhD Drug and Diagnostics Development
Bioresponsive Scaffold Designed to Promote Bone Regeneration Through a Cartilage Intermediate Chelsea Bahney, PhD Drug and Diagnostics Development
Oncogenic Viral Biomarkers in Nonmalignant Human Breast Tissue Kimberly Baltzell, RN, PhD, MS Cancer/Oncology, Drug and Diagnostics Development, Women's Health
Evaluation of BD Vacutainer SST Ultra and Serum Ultra Blood Collection Tubes for Selected Therapeutic Drugs (Sample Collection) Alan H. Wu, PhD Cardiovascular Disease, Drug and Diagnostics Development
QB3 Drug Discovery Michelle Arkin, PhD Drug and Diagnostics Development
Aquaporin-4 (AQP4)-specific T Cells in CNS autoimmunity Scott Zamvil, MD, PhD Immunology
13Th International Meeting of the Society for Natural Immunity April 20-24, 2012 Lewis L. Lanier, PhD Immunology, Training and Capacity Building, Training International Scholars and Clinicians
Molecular Basis for Transmembrane Conduction and Signaling Robert M. Stroud, PhD Genetics
A Specific Mechanism for Non-Specific Inhibition Brian K. Shoichet, PhD Drug and Diagnostics Development
Structure and Engineering of Natural Product Cytochrome P450 Larissa Podust, PhD Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
A Systems-Level Approach to Studying HIV/AIDS Susceptibility and Substance Abuse Sourav Bandyopadhyay, PhD HIV/AIDS, Genetics
Pivotal Study of the Apnex Medical Hypoglossal Nerve Stimulation (HGNS) System to Treat Obstructive Sleep Apnea Drug and Diagnostics Development
Massively Parallel Functioning Testing of Regulatory Elements in Vivo Nadav Ahituv, PhD Immunology, Genetics
Trefoil Factors Regulate Th2 Immunity Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Immunology
Mass Spectrometry Tools in Pursuit of Salivary Biomarkers of Sjogren Syndrome Steven C. Hall, PhD Oral Health, Immunology
Trial of T.cruzi DNA Vaccine in Experimental Model of Disease Challenge Infection Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
The Inflammasome: a Novel Biomarker in ALI/ARDS Michael A. Matthay, MD Immunology
Microbicide Pregnancy Registry--Microbicide Trials Network Juan E. Vargas, MD Sexually Transmitted Infections (STIs), Drug and Diagnostics Development, Women's Health, Family Planning
POPGEN: Population Genetics Haplotype Estimation Method in Complex Typing Data Pierre-Antoine Gourraud, PhD Noncommunicable and/or Chronic Disease, Genetics
NP25737 A Phase I Pharmacokinetic and Safety Study of Tocilizumab (TCZ) in Patients Less Than 2 Years Old With Active Systemic Juvenile Idiopathic Arthritis Emily Von Scheven, MD Noncommunicable and/or Chronic Disease, Immunology, Pediatrics
Philips Mra Research Plan B-9 (Dose Aware) Saam Morshed, MD, MPH, PhD Surgery and Anesthesia, Drug and Diagnostics Development
DNA methylation profiling in Rheumatoid Arthritis Lindsey A. Criswell, MD, MPH Immunology
Exploring the role of a novel, polymorphic protein family in M. tuberculosis pathogenesis Tuberculosis, Immunology
Pharmaceutical Sciences and Pharmacogenomics Deanna L. Kroetz, PhD Drug and Diagnostics Development, Pharmacology and Drug Treatment, Residencies, Fellowships, and Postdoctoral Training
Pets and the Infant Microbiome: Effect on Immune Maturation and Atopic Asthma Susan Lynch, PhD Occupational and Environmental Disease, Immunology
NKG2D Unresponsive to Responsive Pre-Stimulated State of Resting NK or CD8+ T Cells Lewis L. Lanier, PhD HIV/AIDS, Immunology
Mobile Phone Platform for Genomic Disease Detection Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Genetics
Preparing for Human Studies Using the Spinlab Polarizer Sarah Nelson, PhD Drug and Diagnostics Development
Wave 80 Fingerstick Pilot Study Christopher D. Pilcher, MD Drug and Diagnostics Development
Pharmacogenetics of Chemotherapy-Induced Toxicity in Breast Cancer Deanna L. Kroetz, PhD Cancer/Oncology, Genetics, Pharmacology and Drug Treatment, Women's Health
Collaborative Molecular Genetic Investigation of Pediatric Myelodysplatic Syndromes Mignon Loh, MD Genetics, Neurology and Mental Health
Clin 0004 Characterization of Viral Hemorrhagic Fevers of Unknown Origin Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Clin 0003 Identification and Characterization of a Putative Novel Poxvirus in the DRC Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Flexible Resorbable Organic and Nanomaterial Therapeutic Systems (FRONTS) Shuvo Roy, PhD Drug and Diagnostics Development
Trans-Synaptic Signaling during Neuromuscular Development Immunology, Neurology and Mental Health
Murine Neuroblastoma Models for Preclinical Therapeutics William Weiss, MD, PhD Cancer/Oncology, Drug and Diagnostics Development
International Collaboration in Chemistry: the Chemical Basis for Allosteric Regulation of G Protein Coupled Receptors Brian K. Shoichet, PhD Drug and Diagnostics Development
A 2D Device to Verify Deformable Image Registration in Medicine Drug and Diagnostics Development
Nanoengineered Thin Film Devices for Ocular Drug Delivery Tejal A. Desai, PhD Drug and Diagnostics Development
Development of Targeted Anti-Cancer Platinum Analogs Kathleen M. Giacomini, PhD Cancer/Oncology, Drug and Diagnostics Development
Proof of Concept of a Novel Transcatheter Aortic Valve Elaine E. Tseng, MD Cardiovascular Disease, Drug and Diagnostics Development
Self-Assembled DNA Devices for Nanoscale Manipulation of Immune Signal Transduction Shawn M. Douglas, PhD Drug and Diagnostics Development
Pathogen Discovery in PREDICT Human and Wildlife samples to Detect and Identify Viruses Present, Both Known and Novel Charles Y. Chiu, MD, PhD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Escaneo genomico completo del paciente con diabetes tipo 2 para la busqueda de nuevos marcadores de asociacion con enfermedad Esteban G. Burchard, MD, MPH Diabetes, Genetics
Preliminary evaluation of ReLIA Point-of-Care Analyzer for Cardiac Troponin Alan H. Wu, PhD Drug and Diagnostics Development
Genetic Determinants of Capecitabine Toxicity Hope Rugo, MD Genetics, Pharmacology and Drug Treatment
Mechanisms of B Cell Responses in Autoimmune Disease: C12-ALE05-CSF Emily Von Scheven, MD Immunology
Sanofi-Aventis SAR650894 Program - Clinical Component Thomas G. Martin, MD Cancer/Oncology, Drug and Diagnostics Development
Sanofi-Aventis SAR650894 Program - Research Component Thomas G. Martin, MD Cancer/Oncology, Drug and Diagnostics Development
Radially Branched Delivery Device - MRI Interventions - URC 20121214 Daniel A. Lim, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health
Fusion Genes As Therapeutic Targets in Malignant Pleural Mesothelioma Il Jin Kim, PhD Cancer/Oncology, Drug and Diagnostics Development
Nanostructured Polymer Films and Microneedles Tejal A. Desai, PhD Drug and Diagnostics Development
An Open-Label, Multicenter Study Evaluating the Safety and Tolerability of Once-Daily Oral Aripiprazole in Children and Adolescents with Tourette's Disorder R. Keith McBurnett, PhD Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health
Microfluid Chip Design Adam Abate, PhD Drug and Diagnostics Development
Linking ABIN-1 to SLE Susceptibility Averil I. Ma, MD Immunology, Neurology and Mental Health
Development of Human mABs to CXCR1 and CXCR2 Immunology
Development of a Pre-ß-1 HDL Diagnostic Assay John P. Kane, MD, PhD Cardiovascular Disease, Drug and Diagnostics Development
Novel Maltodextrin-Based, Bacterial Targeting Probes for Bioimaging of Viable MTB in Vivo Payam Nahid, MD, MPH Drug and Diagnostics Development
Whole Genome Sequencing in Multiple Sclerosis Jorge Oksenberg, PhD Genetics
PACT Production Assistance for Cellular Therapies Michael A. Matthay, MD Noncommunicable and/or Chronic Disease, Drug and Diagnostics Development
Advanced MR Imaging in Patients with Painful, Degenerative Disc Disease. a Pilot Study Drug and Diagnostics Development
CAMBRain app Peter Rechmann, DMD, PhD Oral Health, Drug and Diagnostics Development
Childhood Arthritis and Rheumatology Research Alliance Registry (CARRA Registry): Lupus Nephritis Consensus Treatment Plan Maintenance Phase Emily Von Scheven, MD Immunology
UCSF Cutaneous Immunology Core: OSM Project Opportunistic Infection, Cancer/Oncology, Immunology
A Study to Evaluate the Efficacy and Safety of GFT505 once daily on Steatohepatitis in Patients with Non-Alcoholic Steatohepatitis (NASH). Muhammad Y. Sheikh, MD Noncommunicable and/or Chronic Disease, Drug and Diagnostics Development
Determination of the Biological Variability (BV) of the Hevylite (HL) Assays. Alan H. Wu, PhD Drug and Diagnostics Development
A 6 month Multi-center, Open-label Safety Study of VIMOVO in Adolescents Emily Von Scheven, MD Immunology, Adolescent Health
Genetic Predictors of Bevacizumab Toxicity in CALGB 80405 Deanna L. Kroetz, PhD Genetics, Pharmacology and Drug Treatment
Lysosomal Storage Disorders Genetic Counselor Fellowship (Genzyme 43737) Seymour Packman, MD Noncommunicable and/or Chronic Disease, Genetics, Pediatrics
Convergent CO2 9.3µm Laser in Sealant Placement Peter Rechmann, DMD, PhD Oral Health, Drug and Diagnostics Development
Diagnostic Antibody for Type A Botulism James D. Marks, MD, PhD Infectious Disease, Drug and Diagnostics Development
Resource for X-Ray Tomography of Whole Cells Carolyn A. Larabell, PhD Drug and Diagnostics Development
Mechanisms of B Cell Responses in Autoimmune Disease Maria Dall'Era, MD Oral Health, Immunology
Validation of the MRI Properties of Magnelles Sharmila Majumdar, PhD Drug and Diagnostics Development
Comparative Effectiveness of Rapid Diagnostics for Tuberculosis in Uganda Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Epidemiology and Surveillance
Factor IX studies at UCSF for GBT Matthew Jacobson, PhD Drug and Diagnostics Development
Large-Scale Production and In-Vivo Characterization of Therapeutic DNA Nanodevices Shawn M. Douglas, PhD Drug and Diagnostics Development
Silicon Dialyzer Prototype Shuvo Roy, PhD Drug and Diagnostics Development
Broad Spectrum Antivirals Targeting Envelope Proteolysis and Viral Uncoating Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Public Health Research, Epidemiology, and Surveillance for Hemoglobinopathies (PHRESH) Sickle Cell Disease (SCD)/ Thalassemia Case Reporting James Huang, MD Infectious Disease, Genetics, Health Systems Strengthening, Risk Reduction and Prevention
HIV-Specific T-Cell Responses in Rectal Mucosa Peter W. Hunt, MD Immunology
HIV-Specific T-Cell Responses in Rectal Mucosa Elizabeth Sinclair, PhD HIV/AIDS, Immunology
A User-Friendly Epidemic-Economic Model of Diagnostic Tests for Tuberculosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development, Epidemiology and Surveillance
Effects of CCR5 - delta-32 Heterozygosity on the HIV-1 Reservoir Steven G. Deeks, MD HIV/AIDS, Immunology, Genetics
Transition to Independence: Optimizing Outcomes in Childhood-onset Lupus Erica F. Lawson, MD Immunology, Pediatrics
An optogenetic method to rapidly and reversibly titrate protein levels in cells Orion D. Weiner, PhD Genetics
Fellowship in Clinical Biochemical Genetics Seymour Packman, MD Genetics, Residencies, Fellowships, and Postdoctoral Training
High Throughput Measurement of Envelope Gene Diversity for an HIV Incidence Assay Christopher D. Pilcher, MD HIV/AIDS, Drug and Diagnostics Development
Identification of Causal Variants in Psoriasis Wilson J. Liao, MD Genetics
Cross-Sectional Examination of Cerebrospinal Fluid Kinetic Biomarkers of Axonal Transport for Amyotrophic Lateral Sclerosis (Als) Diagnosis and Progression Richard W. Price, MD Drug and Diagnostics Development
Accurate, long-read sequencing with droplet-microfluidic barcoding Adam Abate, PhD Infectious Disease, Cancer/Oncology, Genetics
Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-of-Care Setting Alan H. Wu, PhD Drug and Diagnostics Development
Deep Sequencing Clinical Analysis Tool for Infectious Disease Steven A. Miller, MD, PhD Infectious Disease, Drug and Diagnostics Development
Evaluation of the Samsung LABGEO IVD-A20 CHF Test in a Point-Of-Care Setting Alan H. Wu, PhD Drug and Diagnostics Development
Performance Evaluation of the Bio-Rad Geenius HIV-1/2 Supplemental Assay Christopher D. Pilcher, MD HIV/AIDS, Drug and Diagnostics Development
Identification and Validation of Targets of Phenotypic High Throughput Screening Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
Assessing transgenerational effects of Pthalates on primordial germ cells Diana J. Laird, PhD Genetics, Pediatrics, Newborn and Infant Health
Clinitek Novus Second Clinical Trial Protocol Alan H. Wu, PhD Drug and Diagnostics Development
Genetics of Mammographic Density in Ashkenazi Jews Elad Ziv, MD Cancer/Oncology, Genetics
Alfred P. Sloan Foundation Fellowship Ryan Hernandez, PhD Genetics
Genetic Architecture of Complex Traits in Admixed Populations Neil J. Risch, PhD Genetics
High throughput proteomics to dissect Chlamydia-host cell interactions Joanne N. Engel, MD, PhD Infectious Disease, Sexually Transmitted Infections (STIs), Genetics, Risk Reduction and Prevention
Study for Sample Acquisition for Patients Diagnosed with S. aureus Bacteremia Henry Chambers, MD Infectious Disease, Drug and Diagnostics Development, Epidemiology and Surveillance
Health Professional Research Preceptorship Lindsey A. Criswell, MD, MPH Immunology
A Multicenter, Randomized, Placebo-Controlled Study of SBC-102 in Patients with Lysosomal Acid Lipase Deficiency John P. Kane, MD, PhD Genetics
High-Throughput Phenotyping and Continuous Evolution Systems Adam Abate, PhD Drug and Diagnostics Development
Donation of Primaquine for the UCSF-Sponsored Phase 2A Dose Escalation Study of the Efficacy, Safety and Pharmacokinetics of Low Single-Dose Primaquine for Gametocytocidal Activity against P. Falciparum in Sub-Saharan Africa Roland D. Gosling, MSc, PhD Malaria, Drug and Diagnostics Development
A Collaborative Approach to the Design of a Genetically-Stable Oral Polio Vaccine (OPV-2) Raul Andino-Pavlovsky, PhD Infectious Disease, Drug and Diagnostics Development
CANCELED - Gene regulation and function in early embryos (2 R01 HD072046-01A1) Thomas B. Kornberg, PhD Genetics
Gender-specific Differences Affecting Reactivation of Latent HIV in Treated Patients Steven G. Deeks, MD HIV/AIDS, Immunology, Women's Health
Community Acquired Bacterial Pneumonia (CABP) Instrument Development: Concept Elicitation and Cognitive Debrief Interviews Drug and Diagnostics Development
Understanding the role of treatment timing cells and human genetics to explain why HIV drugs do not cure HIV Frederick M. Hecht, MD HIV/AIDS, Drug and Diagnostics Development, Immunology
Novel Maltodextrin-Based, Bacterial Targeting Probes for Bioimaging of Viable MTB In Vivo Payam Nahid, MD, MPH Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development
Integrative Pharmacology Approach to Understand Mechanisms of Tuberculosis Drug Resistance Rada Savic, PhD Zoonosis, Emerging Disease, and Drug Resistance, Tuberculosis, Drug and Diagnostics Development
Micro- and Nano-Structured Biopolymer Thin Film Devices for Small Molecule Drug Delivery Tejal A. Desai, PhD Drug and Diagnostics Development
HIV cure with CCR5 negative human IPS hematopoietic stem cells Jay A. Levy, MD HIV/AIDS, Drug and Diagnostics Development, Immunology
Characterization of Familial Advanced Sleep Phase Syndrome Louis J. Ptacek, MD Genetics
A Specific Mechanism for Non-Specific Inhibition Brian K. Shoichet, PhD Immunology
UZ-UCSF CTU Spilhaus Clinical Research Site HPTN 076 2nd Protocol Funding Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development
Parirenyatwa - International Maternal Pediatric Adolescent AIDS Clinical Trials Group UZ UCSF CTU Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
Plasmodium Falciparum Infection and Interference with Effective B Cell Memory Bryan R. Greenhouse, MD Malaria, Immunology, Pediatrics
IMPAACT Yr 08 P1077 CTU MOU #2 - Parirenyatwa Zvavahera Chirenje, MD, FRCOG Drug and Diagnostics Development, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
IMPAACT Yr 08 P1077 CTU MOU #2 - Seke North Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health, Labor and Delivery, Family Planning, Newborn and Infant Health, Risk Reduction and Prevention
A Phase 2b, Multicenter, Open-Label Study to Investigate the Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination and Sofosbuvir + Ribavirin for Subjects With Chronic Hepatitis C Virus (HCV) and Inherited Bleeding Disorders Norah A. Terrault, MD Infectious Disease, HIV/AIDS, Drug and Diagnostics Development
NSW-QB3 Rosenman Institute Scholarship Program Regis B. Kelly, MD Drug and Diagnostics Development, Residencies, Fellowships, and Postdoctoral Training
Human Natural Killer Cell Recognition of Cytomegalovirus Lewis L. Lanier, PhD HIV/AIDS, Immunology
A Web-Based Automatic Virtual Screening System Brian K. Shoichet, PhD Drug and Diagnostics Development
Rheumatology Fellowship Training Award 2014 Erica F. Lawson, MD Immunology, Residencies, Fellowships, and Postdoctoral Training
Identifying and targeting HIV persistence in T Cell subsets during ART Steven G. Deeks, MD Drug and Diagnostics Development, Immunology, Genetics
Newborn Screening Program for Sickle Cell James Huang, MD Genetics, Newborn and Infant Health
Automated smear-positive tuberculosis diagnosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
Elucidating the Fundamental Biology of Memory Regulatory T cells in Skin Cancer/Oncology, Immunology
Designing a Sonographic Medium for Low Resource Settings Drug and Diagnostics Development
Genetic Diversity as a Determinant of Viral Adaptation and Pathogenesis Raul Andino-Pavlovsky, PhD Infectious Disease, Immunology
Programing Biomolecular Nanodevices For Targeted Immune Cell Recognition and Payload Delivery Shawn M. Douglas, PhD Drug and Diagnostics Development
The Amyotrophic Lateral Sclerosis (ALS)/Parkinsonism-Dementia Complex of Guam: Exploring the Mechanism of a Rare Tauopathy Michael D. Geschwind, MD, PhD Genetics, Neurology and Mental Health
Creating Maps of 4D Brain Images to Unravel Dementia Heterogeneity of Aging HIV Population Victor G. Valcour, MD, PhD Drug and Diagnostics Development, Dementia and Cognitive Impairment
Barriers to point-of-care G6PD testing for P.vivax malaria in Malaysia: a qualitative study Jessica Jaswal, MS Malaria, Drug and Diagnostics Development, Access or Barriers to Care
Treatment of pulmonary fibrosis with inhibitors of integrin alphavbeta1. Dean Sheppard, MD Chronic Respiratory Disease, Drug and Diagnostics Development, Immunology
Treatment of SLE with ajulemic acid,a non-psychoactive cannabinoid derivative Maria Dall'Era, MD Immunology
Life After Pediatric Sepsis Evaluation, LAPSE Anil Sapru, MD Drug and Diagnostics Development, Pharmacology and Drug Treatment, Pediatrics
Pathogen characterization and discovery by deep sequencing of two major vectors associated with Lyme disease and other tickborne infections Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Metabiota - Viral Surveillance for the PREDICT Program 20150410 Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development
A Novel Myeloid Subset Mediating Tolerance to Malaria Mary F. Fontana, PhD Malaria, Immunology
Evaluation of Pao Pereira, a natural product of the extract of rainforest tree, in malignant brain tumor cell lines Nicholas Butowski, MD Cancer/Oncology, Drug and Diagnostics Development
Discovery of benzoxaboroles for the treatment of cryptosporidiosis Philip J. Rosenthal, MD Infectious Disease, Drug and Diagnostics Development
UZ-UCSF Clinical Trials Unit Zvavahera Chirenje, MD, FRCOG HIV/AIDS, Drug and Diagnostics Development, Women's Health, Family Planning, Pediatrics, Newborn and Infant Health
Biostatistical analysis of Mycobacterium Tuberculosis Biomarkers for Diagnosis and Cure Rada Savic, PhD Tuberculosis, Drug and Diagnostics Development
Philippine-UC Collaboratory for Device Innovation (Education/Training Award) Michael R. Harrison, MD Zoonosis, Emerging Disease, and Drug Resistance, Malaria, Drug and Diagnostics Development, Genetics, Training International Scholars and Clinicians
Exploring the Role of Semen Amyloids in Promoting HIV Infection and Fertilization Nadia Roan, PhD HIV/AIDS, Drug and Diagnostics Development, Family Planning
High Throughput Screening of Philippine Terrestrial and Marine Organisms for Antimalarial Properties and Identification of Novel Drug Targets Joseph L. Derisi, PhD Malaria, Drug and Diagnostics Development
High Throughput Screening of Philippine Terrestrial and Marine Organisms for Antimalarial Properties and Identification of Novel Drug Targets Joseph L. Derisi, PhD Malaria, Drug and Diagnostics Development
Molecular genetic, host-derived and clinical determinants of long-term survival in glioblastoma Jennifer L. Clarke, MD, MPH Cancer/Oncology, Genetics
Genetic and epigenetic contributions to Sjogrens syndrome Lindsey A. Criswell, MD, MPH Eye Disease and Blindness, Oral Health, Genetics
Health Professional Research Preceptorship Lindsey A. Criswell, MD, MPH Immunology, Residencies, Fellowships, and Postdoctoral Training
RAPID: Ebola virus population structure, genetic diversity and evolution Raul Andino-Pavlovsky, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Health Professional Research Preceptorship Lindsey A. Criswell, MD, MPH Immunology, Residencies, Fellowships, and Postdoctoral Training
NIH-NIAID - MAC isolates for Study at NIH 20150629 Jennifer M. Puck, MD Infectious Disease, Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
CCD Study- RNA Sequencing Charles Y. Chiu, MD, PhD Infectious Disease, Drug and Diagnostics Development
CHRP Disparities Initiative: UCSF CFAR Conference Award Paul A. Volberding, MD HIV/AIDS, Drug and Diagnostics Development, Pharmacology and Drug Treatment
Interferon-independent mechanisms of malaria restriction by helper T cells J. Michael McCune, MD, PhD HIV/AIDS, Malaria, Immunology
Enabling New Translational Discoveries Using a Genomic Data-Driven Nosology Cancer/Oncology, Immunology
Hologic - Analytical sensitivity comparison of a new molecular assay for Plasmodium detection with a qualitative nested PCR assay and a quantitative PCR assay 20150330 Bryan R. Greenhouse, MD Malaria, Drug and Diagnostics Development
Biomarkers for Malaria Eradication (BIOME) Bryan R. Greenhouse, MD Malaria, Drug and Diagnostics Development
Streamlined TB Diagnosis Adithya Cattamanchi, MD Tuberculosis, Drug and Diagnostics Development
An Ultrasensitive in Vivo Latent HIV Viral Outgrowth Assay Using Humanized Mice Timothy J. Henrich, MD HIV/AIDS, Drug and Diagnostics Development
Medical and Graduate Student Preceptorship - Mok Lindsey A. Criswell, MD, MPH Immunology, Residencies, Fellowships, and Postdoctoral Training
Detection of C. trachomatis on eye swabs Julius Schachter, PhD Eye Disease and Blindness, Drug and Diagnostics Development
QB3 Entrepreneurship, Train the trainers program Regis B. Kelly, MD Drug and Diagnostics Development, Training and Capacity Building, Training International Scholars and Clinicians
Reactivation of latent HIV using recombinant galectin-9 HIV/AIDS, Immunology
Real-Time Detection of Bloodborne Pathogens by Unbiased Nanopore Sequencing 20150506 Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Policy, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, International Health Policy, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training
Characterization of Gallic Acid as a Novel HIV Microbicide Candidate Nadia Roan, PhD HIV/AIDS, Drug and Diagnostics Development, Women's Health
Defining critical events in early HIV infection-effects of alcohol and early ART J. Michael McCune, MD, PhD HIV/AIDS, Immunology, Substance Abuse
Genetic Disease Laboratory and Genetic Disease Screening Program on Clinical Laboratory Improvement Amendments (CLIA) 15-10151 Alan H. Wu, PhD Genetics
A pilot study of DNA methylation and response to treatment in RA Lindsey A. Criswell, MD, MPH Immunology
Genome Research in African American Scleroderma Patients (GRASP) Consortium Lindsey A. Criswell, MD, MPH Immunology
Patient beliefs about the relationship between Chronic Non-Cancer Pain (CNCP) management, alcohol and marijuana use in safety net, primary health care settings Jorge Ramirez, MD, MPH Drug and Diagnostics Development
Fecal microbial transplantation to reduce HIV-associated inflammation Ma Somsouk, MD, MAS HIV/AIDS, Drug and Diagnostics Development
Proteomics Analysis of Host-Pathogen Interactions in Histoplasma Anita Sil, MD, PhD Opportunistic Infection, Immunology
Funding-NSW-QB3 Rosenman Institute Scholarship Program Regis B. Kelly, MD Drug and Diagnostics Development, Residencies, Fellowships, and Postdoctoral Training
Discovery of novel, ubiquitin-regulated mechanisms of TB control by macrophages Tuberculosis, Immunology
Developmental and Hyperactive Ras Tumor SPORE Kevin M. Shannon, MD Cancer/Oncology, Genetics
Towards Therapeutics for Neurodegenerative Diseases Stanley B. Prusiner, MD Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
Investigating Mechanisms of HIV Persistence in the Gut Peter W. Hunt, MD HIV/AIDS, Immunology
Image-Based Numerical Predictions of Hemodynamics following Vascular Intervention David A. Saloner, PhD Cardiovascular Disease, Drug and Diagnostics Development, Neurology and Mental Health
Mechanism of enterovirus replication Raul Andino-Pavlovsky, PhD Drug and Diagnostics Development
Impact of Sirolimus (Rapamycin) on HIV-1 Persistence and Immune Function Timothy J. Henrich, MD HIV/AIDS, Drug and Diagnostics Development
Extending ASD risk locus discovery to the non-coding genome Genetics, Neurology and Mental Health
LOC-IMPAACT Leadership Group Francesca T. Aweeka, PharmD HIV/AIDS, Tuberculosis, Drug and Diagnostics Development, Pharmacology and Drug Treatment, Women's Health, Pediatrics, Newborn and Infant Health, Systematic Reviews and Guideline Development
Real-Time Unbiased Pathogen Detection in Febrile Illnesses by Nanopore Sequencing Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Drug and Diagnostics Development
Mechanism regulating ErbB signaling network in head and neck cancer Randall H. Kramer, PhD Cancer/Oncology, Immunology
Targeting Allosteric Sites to Modulate Protein Interactions and Function Charles S. Craik, PhD Drug and Diagnostics Development
Development of the infant gastrointestinal virome and shedding of oral polio and rotavirus vaccines in Bangladeshi and US infants Charles Y. Chiu, MD, PhD Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), Drug and Diagnostics Development, Newborn and Infant Health
Role of SOX2 O-GIcNAcylation in pluripotency Genetics
Binding-Site Modeling with Multiple-Instance Machine-Learning Cancer/Oncology, Drug and Diagnostics Development
New York Center for Collaborative Research in Common Disease Genomics Esteban G. Burchard, MD, MPH Genetics
A Novel Microfluidic HIV-1 Co-Culture Assay to Quantify Latent Reservoirs Timothy J. Henrich, MD HIV/AIDS, Drug and Diagnostics Development
Polyclonal Tregs to Promote Tolerance in Pediatric Liver Transplant Recipients Sandy Feng, MD, PhD Surgery and Anesthesia, Immunology
Risk-Benefit Trade-Offs for Whole Genome Sequencing Kathryn A. Phillips, PhD Genetics
Translational Investigation of KRas & NF1 in Myeloid Leukemia Kevin M. Shannon, MD Cancer/Oncology, Genetics
Genetic and molecular pathophysiology of ATS Louis J. Ptacek, MD Cardiovascular Disease, Genetics
Provider Practices in Non-Malarial Fevers: A Pilot Study in Malawi Kimberly Baltzell, RN, PhD, MS Drug and Diagnostics Development, Pharmacology and Drug Treatment
Immunologic determinants of age-related macular degeneration Peter W. Hunt, MD Eye Disease and Blindness, Immunology, Aging
Discovery of Oxaboroles as New Antimalarial Agents Philip J. Rosenthal, MD Malaria, Drug and Diagnostics Development
Influence of Heme on Hepatic Cytochrome P450 Turnover Maria A. Correia, PhD Drug and Diagnostics Development
Phase III Quinolone Meta-Analysis Rada Savic, PhD Drug and Diagnostics Development
Center for Multi- and Trans-ethnic Mapping of Mendelian and Complex Diseases Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pediatrics
Initiation of allergic immunity by parasites Richard M. Locksley, MD Immunology
Pharmacogenomics of Bronchodilator Response in Minority Children with Asthma Esteban G. Burchard, MD, MPH Chronic Respiratory Disease, Genetics, Pharmacology and Drug Treatment, Pediatrics
BMI Bioinformatics Training Grant Patricia C. Babbitt, PhD Genetics, Residencies, Fellowships, and Postdoctoral Training
Multi-Institutional Randomized Controlled Trial Evaluating Use of Arista Absorbable Surgical Hemostatic Powder Rahul Seth, MD Surgery and Anesthesia, Drug and Diagnostics Development
Placental Malaria: The Role of Macrophages in Placental Inflammation - RSDP Valderramos Stephanie L. Valderramos, MD, PhD Malaria, Immunology
Placental Malaria: The Role of Macrophages in Placental Inflammation - RSDP Valderramos Burroughs Wellcome Fund Stephanie L. Valderramos, MD, PhD Malaria, Immunology
Swaziland Serology Technical Assistance Michelle Hsiang, MD Malaria, Drug and Diagnostics Development
Population Genetics of the PO1 Locus of SIV and HIV-1 Eric L. Delwart, PhD HIV/AIDS, Genetics

Active Investigators: 118