Dementia and Cognitive Impairment

Active Projects: 34

Project
Investigator All Topics Start date End date
Traumatic brain injury education Alisa Gean, MD Neurology and Mental Health, Dementia and Cognitive Impairment
A Double-Blind, Placebo-Controlled, Randomized, Parallel Group, 12-Month Safety and Efficacy Trial of Leuco-methylthioninium bis(hydromethanesulfonate) in Subjects with Behavioral Variant Frontotemporal Dementia (bvFTD) Adam L. Boxer, MD, PhD Dementia and Cognitive Impairment
A Multicenter, Multinational, Randomized, Double Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Laquinimod (0.5, 1.0 and 1.5 mg/day) as Treatment in Patients with Huntington's Disease Michael D. Geschwind, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
ACC: Callosal Agenesis as a Window into Common Neurodevelopment Disorders Elliott H. Sherr, MD, PhD Genetics, Neurology and Mental Health, Dementia and Cognitive Impairment
Collaboration on research and development of therapeutics and molecular diagnostics for neurodegenerative diseases Stanley B. Prusiner, MD Neurology and Mental Health, Dementia and Cognitive Impairment
Community-based pediatric rehabilitation in India Mitul R. Kapadia, MD, MPH Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Pediatrics, Access or Barriers to Care
Degenerative and Dementing Diseases of Aging Stanley B. Prusiner, MD Neurology and Mental Health, Dementia and Cognitive Impairment, Aging
Diffusion Tensor Imaging Processing and Group Analysis Norbert Schuff, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
Does Outpatient Palliative Care Improve Patient-Centered Outcomes in Parkinson's Disease Neurology and Mental Health, Dementia and Cognitive Impairment
Effects of Polydrug Use, Adulterants and HIV on Cardiac Injury in Homeless Women Elise Riley, PhD Dementia and Cognitive Impairment, Women's Health, Access or Barriers to Care, Stigma and Discrimination, Substance Abuse
Environment and cognitive decline in older hispanics Mary N. Haan, DrPH, MPH Dementia and Cognitive Impairment, Aging
Epidemiology of stroke Anthony S. Kim, MD Cardiovascular Disease, Neurology and Mental Health, Dementia and Cognitive Impairment
Formation and Spreading of Tau Prions in Chronic Traumatic Encephalopathy Stanley B. Prusiner, MD Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD
Global Brain Health Institute Victor G. Valcour, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment, Training International Scholars and Clinicians, Residencies, Fellowships, and Postdoctoral Training
Inhibitors of caspase-6 as potential Alzheimer's disease therapeutics Michelle Arkin, PhD Dementia and Cognitive Impairment
Interventions for Symptom Management in Older Patients with HAND Victor G. Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment
Lifecourse health, cerebral pathology and ethnic disparities in dementia Maria Glymour, ScD, MS Dementia and Cognitive Impairment
Living Alone in Older Age with Alzheimer's Disease Neurology and Mental Health, Dementia and Cognitive Impairment, Aging
Living Alone in Older Age with Cognitive Impairment Neurology and Mental Health, Dementia and Cognitive Impairment, Aging
Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) Howard J. Rosen, MD Dementia and Cognitive Impairment
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor G. Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment, Residencies, Fellowships, and Postdoctoral Training
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases Michael D. Geschwind, MD, PhD Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
Multimodal Imaging in Frontotemporal Degeneration Howard J. Rosen, MD Noncommunicable and/or Chronic Disease, Neurology and Mental Health, Dementia and Cognitive Impairment
National Alzheimer's Coordinating Center, NACC (Renewal for Y16-20) Bruce L. Miller, MD Dementia and Cognitive Impairment
Neuropathological changes underlying clinical heterogeneity in Alzheimer disease Lea T. Grinberg, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment, Residencies, Fellowships, and Postdoctoral Training
New Approaches to Dementia Heterogeneity (P50) Bruce L. Miller, MD Dementia and Cognitive Impairment
Predicting progression of human prion disease Michael D. Geschwind, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
Predictors of Cognitive Aging across the Lifecourse Kristine Yaffe, MD Noncommunicable and/or Chronic Disease, Neurology and Mental Health, Dementia and Cognitive Impairment, Risk Reduction and Prevention
Testosterone's role in sex-specific outcomes after early anesthesia Jeffrey Sall, PhD, MD Surgery and Anesthesia, Neurology and Mental Health, Dementia and Cognitive Impairment, Pediatrics, Adolescent Health
The Frontotemporal Lobar Degeneration Clinical Research Consortium Adam L. Boxer, MD, PhD Neurology and Mental Health, Dementia and Cognitive Impairment
Track TBI Biorepository Subcontract Geoffrey Manley, MD, PhD Dementia and Cognitive Impairment
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical Trajectories Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD
Treatment of Incontinence without Memory Problems (TRIuMPh) Dementia and Cognitive Impairment, Aging
Understanding literacy acquisition through immersion in foreign languages Fumiko Hoeft, MD, PhD Dementia and Cognitive Impairment

Active Projects: 63

Project
Investigator All Topics Start date End date
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Sequential Cohort, Dose-Ranging Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TPI-287 in Patients with Mild to Moderate Alzheimer's Disease Adam L. Boxer, MD, PhD Noncommunicable and/or Chronic Disease, Dementia and Cognitive Impairment
Accelerated Biological Aging in Schizophrenia Owen Wolkowitz, MD Dementia and Cognitive Impairment
Aging Among the Homeless: Geriatric Conditions, Health and Healthcare Outcomes Margot B. Kushel, MD Dementia and Cognitive Impairment, Trauma and PTSD, Access or Barriers to Care, Stigma and Discrimination, Substance Abuse
Alameda MHSA-Early Intervention at Onset of First Psychosis Rachel Loewy, PhD Dementia and Cognitive Impairment, Adolescent Health
ALS Center of Excellence at UCSF Catherine E. Lomen-Hoerth, MD, PhD Dementia and Cognitive Impairment
Burden, Depression, and Health in Dementia Caregivers: the Role of Emotion Bruce L. Miller, MD Neurology and Mental Health, Dementia and Cognitive Impairment
California Non-AD Diagnostic Reliability Consortium Julene Johnson, PhD Dementia and Cognitive Impairment, Aging
Childhood Lead Poisoning Prevention George W. Rutherford, MD Occupational and Environmental Disease, Dementia and Cognitive Impairment, Pediatrics, Systematic Reviews and Guideline Development
Clinical and biological markers of disease progression in familial FTD Howard J. Rosen, MD Dementia and Cognitive Impairment
Creating Maps of 4D Brain Images to Unravel Dementia Heterogeneity of Aging HIV Population Victor G. Valcour, MD, PhD Drug and Diagnostics Development, Dementia and Cognitive Impairment
Dementia in HIV Patients over 60 Years of Age Victor G. Valcour, MD, PhD HIV/AIDS, Neurology and Mental Health, Dementia and Cognitive Impairment
Developing Tau Prion Therapeutics for Chronic Traumatic Encephalopathy Stanley B. Prusiner, MD Noncommunicable and/or Chronic Disease, Dementia and Cognitive Impairment, Trauma and PTSD
Development and Validation of a Diagnostic Tool for HIV Dementia Ana-Claire L. Meyer, MD HIV/AIDS, Dementia and Cognitive Impairment
Development of Potent/Selective Lipoxygenase Therapeutics against Stroke Injury Matthew Jacobson, PhD Dementia and Cognitive Impairment
Effect of Cognitive Remediation on BDNF Levels in Schizophrenia Synthia Mellon, PhD Dementia and Cognitive Impairment
Effect of Passive Immunization on the Progression of Mild Alzheimer's Disease: Solanezumab(LY2062430) versus Placebo Adam L. Boxer, MD, PhD Pharmacology and Drug Treatment, Dementia and Cognitive Impairment
Epidemiology of Functional Status in Elderly Hispanics Mary N. Haan, DrPH, MPH Dementia and Cognitive Impairment
Extension of Phase II Studies ABE4869g and ABE4955g in Patients with Mild to Moderate Alzheimer Disease Adam L. Boxer, MD, PhD Dementia and Cognitive Impairment
Eye Movement Control in Normal Elderly and MCI Adam L. Boxer, MD, PhD Noncommunicable and/or Chronic Disease, Dementia and Cognitive Impairment
Four Repeat Tauopathy Neuroimaging Initiative Adam L. Boxer, MD, PhD Dementia and Cognitive Impairment
Frontotemporal Dementia: Genes, Images, and Emotions Bruce L. Miller, MD Dementia and Cognitive Impairment
Genetic architecture of memory and executive functioning in Alzheimer's disease Glymour Subcontract with University of Washington. PI: Paul Crane Reference: Grant number 1A01AG042437-01A1 Maria Glymour, ScD, MS Neurology and Mental Health, Dementia and Cognitive Impairment
HIV Tropism, Persistence, Inflammation, and Neurocognition in Therapy Initiation Richard W. Price, MD HIV/AIDS, Dementia and Cognitive Impairment
HIV-1 Specific Immune Responses in Thai Individuals with HIV Dementia Victor G. Valcour, MD, PhD HIV/AIDS, Dementia and Cognitive Impairment
HIV-associated neurocognitive impairment and antiretroviral adherence: secondary data analysis of the THINK2 prospective cohort study Laura Saucier, MS HIV/AIDS, Dementia and Cognitive Impairment
Investigating parvalbumin interneuron activity: implications for schizophrenia and potential therapies Dementia and Cognitive Impairment
Isolated Executive Impairment and Cognitive Decline Julene Johnson, PhD Dementia and Cognitive Impairment
Long-Term Central Nervous System (CNS) Consequences of Treatment during Acute Infection Victor G. Valcour, MD, PhD Dementia and Cognitive Impairment
Macrostructural and Microstructural Imaging Biomarkers of Traumatic Brain Injury Pratik Mukherjee, MD, PhD Dementia and Cognitive Impairment, Trauma and PTSD
Managing Diagnostic Uncertainty: An Examination of the Interplay of Technology, Medical Knowledge, and Law in Diagnostic Practice. The Case of Epilepsy Vincanne Adams, PhD Dementia and Cognitive Impairment, Systematic Reviews and Guideline Development
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Katherine L. Possin, PhD Drug and Diagnostics Development, Dementia and Cognitive Impairment
Medical Scientist Training Program Mark S. Anderson, MD, PhD Noncommunicable and/or Chronic Disease, Cancer/Oncology, Dementia and Cognitive Impairment, Residencies, Fellowships, and Postdoctoral Training, UCSF Professional Education
Molecular Pathogenesis of Age Dependent Neurodegeneration Stanley B. Prusiner, MD Neurology and Mental Health, Dementia and Cognitive Impairment
MRI Signature of PD Heterogeneity Norbert Schuff, PhD Dementia and Cognitive Impairment
Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression Catherine E. Lomen-Hoerth, MD, PhD Dementia and Cognitive Impairment
National Alzheimer's Coordinating Center, NACC Bruce L. Miller, MD Dementia and Cognitive Impairment
New Approaches to Dementia Heterogeneity Bruce L. Miller, MD Neurology and Mental Health, Dementia and Cognitive Impairment
Oxidant Mechanisms in Neonatal Brain Injury Donna M. Ferriero, MD Neurology and Mental Health, Dementia and Cognitive Impairment, Newborn and Infant Health
Oxidant Mechanisms of Neonatal Brain Injury Donna M. Ferriero, MD Dementia and Cognitive Impairment, Newborn and Infant Health
Peripheral Reservoir of HIV Monocytes Pivotal to Cognition in HIV Victor G. Valcour, MD, PhD HIV/AIDS, Neurology and Mental Health, Dementia and Cognitive Impairment
PET ligands for measuring tau in the brains of combatants after traumatic brain injury. Stanley B. Prusiner, MD Dementia and Cognitive Impairment, Trauma and PTSD
Phase I Multiple Ascending Dose Trial of the MT Stabilizer TPI-287 for Alzheimer Disease (AD) Adam L. Boxer, MD, PhD Pharmacology and Drug Treatment, Dementia and Cognitive Impairment
Phase II Study to Evaluate the Efficacy and Safety of MABT5102A in Patients with Mild to Moderate Alzheimer's Diseases Adam L. Boxer, MD, PhD Dementia and Cognitive Impairment
Pilot Trial in Wearable computing technology in mild to moderate Alzheimer's type Dementia: development of an Automated Reality Orientation App Pierre Theodore, MD Dementia and Cognitive Impairment
Predictors & Outcomes of Cognitive Trajectories in the Oldest of Old Kristine Yaffe, MD Dementia and Cognitive Impairment
Predictors of MCI/Dementia among the Oldest Old Women Kristine Yaffe, MD Dementia and Cognitive Impairment, Women's Health
Psychometric Integrative Technology for Cognitive Health Research Maria Glymour, ScD, MS Neurology and Mental Health, Dementia and Cognitive Impairment
Racial Disparities in Cognitive Impairment Health Outcomes PA00-019 Dementia and Cognitive Impairment
Screening for Inhibitors of p300-Mediated Tau Acetylation for Alzheimer's Disease Michelle Arkin, PhD Dementia and Cognitive Impairment
Social Resources That Preserve Functional Independence After Memory Loss Maria Glymour, ScD, MS Dementia and Cognitive Impairment
Study of Osteoporotic Fractures Kristine Yaffe, MD Dementia and Cognitive Impairment, Women's Health, Aging
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia Ana-Claire L. Meyer, MD HIV/AIDS, Dementia and Cognitive Impairment
The Development of a Tool to Identify Peripheral Neuropathy and HIV Associated Dementia Ana-Claire L. Meyer, MD HIV/AIDS, Dementia and Cognitive Impairment
The effects of alcohol on acute HIV associated neurocognitive disorders Christopher D. Pilcher, MD HIV/AIDS, Dementia and Cognitive Impairment, Substance Abuse
The Frontotemporal Lobar Degeneration Neuroimaging Initiative Howard J. Rosen, MD Dementia and Cognitive Impairment
The Translational Alzheimer Disease Research Program Katherine L. Possin, PhD Dementia and Cognitive Impairment
The UCSF and UNMC Dementia Care Ecosystem: Using Innovative Technologies to Personalize and Deliver Coordinated Dementia Care Bruce L. Miller, MD Dementia and Cognitive Impairment
Towards Therapeutics for Neurodegenerative Diseases Stanley B. Prusiner, MD Drug and Diagnostics Development, Neurology and Mental Health, Dementia and Cognitive Impairment
UCSF - GAP Collaboration: Leveraging the Brain Health Registry for GAP Clinical Trial Recruitment Michael Weiner, MD Neurology and Mental Health, Dementia and Cognitive Impairment
UCSF-Kaiser Building Interdisciplinary Research Careers in Women's Health Program Ruth M. Greenblatt, MD HIV/AIDS, Noncommunicable and/or Chronic Disease, Cancer/Oncology, Cardiovascular Disease, Diet, Exercise, and Obesity, Dementia and Cognitive Impairment, Women's Health, UCSF Professional Education
Undiagnosed PD in the ED: Unrealized Opportunity for Early Intervention Sopiko Jimsheleishvili, MS Dementia and Cognitive Impairment
University of California Global Health Institute Program for Fellows and Scholars Craig Cohen, MD, MPH Sexually Transmitted Infections (STIs), Zoonosis, Emerging Disease, and Drug Resistance, Neglected Tropical Diseases (NTDs), HIV/AIDS, Opportunistic Infection, Tuberculosis, Malaria, Noncommunicable and/or Chronic Disease, Surgery and Anesthesia, Cancer/Oncology, Cardiovascular Disease, Chronic Respiratory Disease, Diabetes, Occupational and Environmental Disease, Diet, Exercise, and Obesity, Malnutrition, Micronutrients, Food Insecurity, Eye Disease and Blindness, Oral Health, Drug and Diagnostics Development, Immunology, Genetics, Pharmacology and Drug Treatment, Neurology and Mental Health, Dementia and Cognitive Impairment, Trauma and PTSD, Women's Health, Aging, Labor and Delivery, Family Planning, Pediatrics, Newborn and Infant Health, Adolescent Health, Health Economics and Policy, Access or Barriers to Care, Immigration and Migration, Stigma and Discrimination, Smoking and Tobacco, International Health Policy, Systematic Reviews and Guideline Development, Epidemiology and Surveillance, Triangulation, Global Strategic Information, Implementation and Behavioral Science, Engagement in Care, Substance Abuse, Treatment Adherence, Health Systems Strengthening, Risk Reduction and Prevention, Residencies, Fellowships, and Postdoctoral Training
Variations in Brain Functional Complexity Across Neurodegeneration Norbert Schuff, PhD Dementia and Cognitive Impairment