Injuries are a leading cause of death and disability but are often neglected as a global health priority. In particular, road traffic injuries disproportionately affect low to middle income countries (LMIC) with 90% of mortalities from injuries occurring in LMICs such as Cameroon. Measures such as trauma audit filters have the potential to reduce morbidity and mortality from injuries by evaluating clinical processes and outcomes. Trauma audit filters are well studied and established in high-income countries; however, little is known regarding context-appropriate trauma audit filters for low to middle income countries. This study aimed to (1) develop trauma audit filters and (2) assess the barriers and facilitators to audit filter implementation for the context of hospitals in Cameroon.