Proof of Concept of a Novel Transcatheter Aortic Valve

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Investigator: Elaine E. Tseng, MD
Sponsor: UC Proof of Concept Program

Location(s): United States

Description

Transcatheter valve implantation within degenerated bioprostheses is a potentially promising treatment for high-risk surgical patients. Clinical experience is limited; however, we have shown in vitro that currently available transcatheter aortic valve sizes did not provide acceptable hemodynamics in small bioprostheses. The objective of this study was to develop a new transcatheter valve that would provide good hemodynamics within degenerated bioprostheses.