Molecular Mechanisms Underlying Tumor Progression Despite Enzalutamide Treatment

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Investigator: Eric J. Small, MD
Sponsor: Oregon Health Sciences University

Location(s): United States

Description

The purpose of this study is to better understand how cancer treatment of Enzalutamide (MDV3100) may affect prostate cancer cells. The research will involve genetic, molecular, cellular and immunologic experiments using blood and tumor specimens. It is hoped that the information gained from these studies will lead to a greater understanding of castrate-resistant prostate cancer, Enzalutamide resistance and potentially, improvements in cancer treatment.