International Case-Control Study of Malignant Glioma
Location(s): United States
Gliomas are a rare and understudied disease that is rapidly fatal. The proposed Case-Control Study of primary malignant Glioma (Gliogene Consortium) includes 13-centers, and will address the role of genetic susceptibility in sporadic cases. It will identify common genetic variants contributing to the risk of Glioma from a genome wide association Study.
Glioma comprises about 40% of all primary brain tumors accounting for as many as 26,000 U.S. and European deaths annually. Inherited Susceptibility plays a role with 2-fold increased risk of Glioma among first-degree relatives of Glioma cases. "Genetic Epidemiology of Glioma International Consortium" address the role of Inherited