Individualized Therapy for Asthma in Toddlers (INFANT) Acetaminophen v. Ibuprofen in Children with Asthma (INFANT-AVICA)

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Investigator: Michael D. Cabana, MD, MPH
Sponsor: Pennsylvania State University

Location(s): United States

Description

The study consists of 2 separate but linked trials to examine treatment therapy for preschool-aged children with persistent asthma.  The purpose of the studies is to examine the preferred treatment forpreschool-aged children with persistent asthma. INFANT and AVICA are two studies combined into one to look at the control of wheezing in children with asthma.

INFANT  will try to find out if one asthma treatment works better than another in toddlers. Another purpose is to see if there is something about a child that helps doctors predict which treatment would work better.
AVICA  is a study to find out if acetaminophen or ibuprofen is the better pain reliever/fever reducer for asthma for  children who are less than 5 years of age. It is possible that medications used to treat fever or body aches work differently in young children with asthma. This difference might depend on their asthma controller treatment.