The Evidence to Policy Initiative (E2Pi) works to narrow the gap between evidence and policy, creating the tools and information policymakers need in order to make informed decisions. We concentrate on topics of greatest current interest to the international community; on complex issues where the current debate can benefit from clarification and simplification; and on areas where there is a clear demand for evidence-based options and recommendations. Accordingly, the topics we work on can be diverse. To date we have provided information, impartial analysis and other tools to support policymaking in the following areas:

• The difficult policy options facing the Geneva-based international financing institutions—especially the Global Fund to Fight AIDS, Tuberculosis and Malaria, and the GAVI Alliance, a public-private partnership for vaccine procurement and delivery—as they respond to international pressure to increase financing, improve impact and expand their mandates
• Mechanisms for measuring the success or failure of innovative new international initiatives, such as the Affordable Medicines Facility-malaria (AMFm)—an effort to increase distribution of effective malaria treatment through the private sector
• Evidence on the health and economic risks of reducing investment in malaria—in order to make the case for long-term, sustained international and domestic financing
• Policies on translating new international commitments to maternal, newborn and child health into concrete and well-funded action on the ground