DNA methylation profiling in Rheumatoid Arthritis

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Investigator: Lindsey A. Criswell, MD, MPH
Sponsor: Rheumatology Research Foundation

Location(s): United States

Description

Rheumatoid arthritis (RA) is a chronic inflammatory disease with potential to cause substantial disability, primarily due to the erosive and deforming process in joints. RA etiology is complex with contributions from genetic and non-genetic factors. Epigenetic changes such as altered patterns of DNA methylation (DNAm), are also present in RA