CD4+ FoxP3 lineage cells in CNS autoimmune disease and therapy

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Investigator: Jeffrey A. Bluestone, PhD
Sponsor: National Multiple Sclerosis Society

Location(s): United States

Description

The specific aims of this proposal are  (1) To characterize specific attributes and contributions of nTregs and aTregs in protection from autoimmune disease using a novel model of EAE, and (2) To examine the stability of Tregs during EAE pathogenesis