CC#15987 - Long-term Follow-up of Subjects Exposed to Lentiviral-based CART-meso-19 Gene Therapy Products in Cancer Studies

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Sponsor: University of Pennsylvania

Location(s): United States

Description

The primary objective of this study is to monitor adult subjects, who as participants of a clinical trial, received T cells modified by a lentiviral vector encoding a chimeric antigen receptor specific for EGFRvIII, for adverse events that may be associated with lentiviral vector gene transfer such as insertional oncogenesis.