Advancing tobacco use treatment for african american smokers
Location(s): United States
African Americans experience the highest levels of tobacco-related disease and death, despite smoking fewer cigarettes per day than Whites. Advancing treatment for African American smokers is a critical public health priority. This study will evaluate the efficacy of varenicline treatment to improve quit rates in African American daily smokers of all smoking levels, with the goal of reducing tobacco-related health disparities.
Our specific aims are to evaluate the efficacy of varenicline to promote abstinence in African American smokers across the continuum of smoking level, to examine efficacy in light smokers and also in moderate to heavy smokers, to characterize nicotine and carcinogen exposure, and to describe biopsychosocial characteristics of this group and evaluate in relation to abstinence. This innovative study will provide the first placebo-controlled evaluatin of varenicline in the full spectrum of African American smokers, and the first to examine varenicline in light smokers. Findings will contribute to advancing effective treatment for African American smokers and for light smokers, and enhancing individualized treatment. Increased treatment efficacy will have major impact on reducing tobacco- related morbidity and mortality in this high-risk population.