Memory and Aging Center

Active Projects: 22

Project Investigator All Organizations Start date
End date
Global Brain Health Institute Victor G. Valcour, MD, PhD Memory and Aging Center
ENROLL-HD -A Prospective Registry Study in a Global Huntington's Disease Cohort Michael D. Geschwind, MD, PhD Memory and Aging Center
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Therapeutic Interventions during Acute Infection to Address the CNS Reservoir for HIV Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
A Double-Blind, Placebo-Controlled, Randomized, Parallel Group, 12-Month Safety and Efficacy Trial of Leuco-methylthioninium bis(hydromethanesulfonate) in Subjects with Behavioral Variant Frontotemporal Dementia (bvFTD) Adam L. Boxer, MD, PhD Memory and Aging Center
Predicting Progression of Human Prion Disease Michael D. Geschwind, MD, PhD Memory and Aging Center
Multimodal Imaging in Frontotemporal Degeneration Howard J. Rosen, MD Memory and Aging Center
New Approaches to Dementia Heterogeneity (P50) Bruce L. Miller, MD Memory and Aging Center
National Alzheimer's Coordinating Center, NACC (Renewal for Y16-20) Bruce L. Miller, MD Memory and Aging Center
The UCSF and UNMC Dementia Care Ecosystem: Using Innovative Technologies to Personalize and Deliver Coordinated Dementia Care Bruce L. Miller, MD Memory and Aging Center
Determinants of Resilience on Youth with HIV Infection and Youth Affected by HIV Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Interventions for Symptom Management in Older Patients with HAND Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center, AIDS Research Institute
Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) Howard J. Rosen, MD Memory and Aging Center
The Frontotemporal Lobar Degeneration Clinical Research Consortium Adam L. Boxer, MD, PhD Memory and Aging Center
Multidisciplinary Fellowship in Dementia Research Bruce L. Miller, MD Memory and Aging Center
A Multicenter, Multinational, Randomized, Double Blind, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Laquinimod (0.5, 1.0 and 1.5 mg/day) as Treatment in Patients with Huntington's Disease Michael D. Geschwind, MD, PhD Memory and Aging Center
A Randomized, Double-Blind, Placebo-Controlled, SingleAscending Dose Study to Assess the Safety, Tolerability,and Pharmacokinetics of C2N-8E12 in Subjects withProgressive Supranuclear Palsy Adam L. Boxer, MD, PhD Memory and Aging Center
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical Trajectories Memory and Aging Center
Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center, AIDS Research Institute
Multi-center evaluation of improved RT-QuIC diagnostic assays for Creutzfeldt-Jakob and other human prion diseases Michael D. Geschwind, MD, PhD Memory and Aging Center
Phase III multicenter multicenter, randomized, double-blind, placebo controlled, parallel group efficacy and safety study of Crenezumbab in patients with propromal to mild Alzheimers disease Adam L. Boxer, MD, PhD Memory and Aging Center
Predicting progression of human prion disease Michael D. Geschwind, MD, PhD Memory and Aging Center

Archived Projects: 37

Project Investigator All Organizations Start date
End date
Cognitive Health and Brain Vulnerability in Aging Insulin Resistant Patients Victor G. Valcour, MD, PhD Memory and Aging Center
Early Diagnosis of Human Prion Disease Michael D. Geschwind, MD, PhD Memory and Aging Center
Dementia in HIV Patients over 60 Years of Age Victor G. Valcour, MD, PhD Memory and Aging Center
Eye Movement Control in Normal Elderly and MCI Adam L. Boxer, MD, PhD Memory and Aging Center
New Approaches to Dementia Heterogeneity Bruce L. Miller, MD Memory and Aging Center
National Alzheimer's Coordinating Center, NACC Bruce L. Miller, MD Memory and Aging Center
Central Nervous System Effects in Acute HIV Seroconversion Victor G. Valcour, MD, PhD Memory and Aging Center
Peripheral Reservoir of HIV Monocytes Pivotal to Cognition in HIV Victor G. Valcour, MD, PhD Memory and Aging Center
HIV and Global Drug Therapies: Peripheral Neuropathy Complications and Mechanisms Victor G. Valcour, MD, PhD Memory and Aging Center
HIV-1 Specific Immune Responses in Thai Individuals with HIV Dementia Victor G. Valcour, MD, PhD Memory and Aging Center
The Frontotemporal Lobar Degeneration Neuroimaging Initiative Howard J. Rosen, MD Memory and Aging Center
Neurodevelopment and Imaging among HIV-infected Children from the PREDICT Study Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Development of Resting-State FMRI As a Biomarker for Alzheimer Disease Bruce L. Miller, MD Memory and Aging Center
Four Repeat Tauopathy Neuroimaging Initiative Adam L. Boxer, MD, PhD Memory and Aging Center
The Translational Alzheimer Disease Research Program Katherine L. Possin, PhD Memory and Aging Center
Mechanisms of Spatial Cognitive Impairment in Neurodegenerative Disease Katherine L. Possin, PhD Memory and Aging Center
Samples from Brazilian Aging Brain Study Group Lea T. Grinberg, MD, PhD Memory and Aging Center
Study of Lytico-Bodig disease (Parkinson-dementia complex of Guam) William W. Seeley, MD Memory and Aging Center
Long-Term Central Nervous System (CNS) Consequences of Treatment during Acute Infection Victor G. Valcour, MD, PhD Global Health Sciences Faculty Affiliate, Memory and Aging Center
Phase II Study to Evaluate the Efficacy and Safety of MABT5102A in Patients with Mild to Moderate Alzheimer's Diseases Adam L. Boxer, MD, PhD Memory and Aging Center
Biomarker Optimization for Progranulin Trials (The BOPT Study) Adam L. Boxer, MD, PhD Memory and Aging Center
DoD-ADNI -Effects of TBI and PTSD on AD in Veterans using Imaging and Biomarkers in ADNI Howard J. Rosen, MD Memory and Aging Center
Burden, Depression, and Health in Dementia Caregivers: the Role of Emotion Bruce L. Miller, MD Memory and Aging Center
Neurobiological Predictors of Huntington's Disease (Predict-HD) Michael D. Geschwind, MD, PhD Memory and Aging Center
Frontotemporal Dementia: Genes, Images, and Emotions Bruce L. Miller, MD Memory and Aging Center
BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects with Mild Alzheimer's Disease Adam L. Boxer, MD, PhD Memory and Aging Center
An Open Label Dose Finding Study of Nimodipine for the Treatment of Frontotemporal Dementia Due to Progranulin Insufficiency From GRN Gene Mutations Adam L. Boxer, MD, PhD Memory and Aging Center
Neurobiological Changes in Network Function and Amyloid Deposition in Alzheimer Disease Memory and Aging Center
Extension of Phase II Studies ABE4869g and ABE4955g in Patients with Mild to Moderate Alzheimer Disease Adam L. Boxer, MD, PhD Memory and Aging Center
Phase I Multiple Ascending Dose Trial of the MT Stabilizer TPI-287 for Alzheimer Disease (AD) Adam L. Boxer, MD, PhD Memory and Aging Center
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Sequential Cohort, Dose-Ranging Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TPI-287 in Patients with Mild to Moderate Alzheimer's Disease Adam L. Boxer, MD, PhD Memory and Aging Center
Clinical and biological markers of disease progression in familial FTD Howard J. Rosen, MD Memory and Aging Center
Establishing Therapeutic Efficacy in Frontotemporal Degeneration Howard J. Rosen, MD Memory and Aging Center
Effect of Passive Immunization on the Progression of Mild Alzheimer's Disease: Solanezumab(LY2062430) versus Placebo Adam L. Boxer, MD, PhD Memory and Aging Center
Causes, treatment and prevention of corticobasal degeneration Adam L. Boxer, MD, PhD Memory and Aging Center
The Amyotrophic Lateral Sclerosis (ALS)/Parkinsonism-Dementia Complex of Guam: Exploring the Mechanism of a Rare Tauopathy Michael D. Geschwind, MD, PhD Memory and Aging Center
U.S. Army Medical Research Acquisition Activity (USAMRAA) Victor G. Valcour, MD, PhD Memory and Aging Center