Department of Biochemistry and Biophysics

Active Projects: 12

Project Investigator All Organizations Start date
End date
Translational Studies Linking Aging and Cancer Cynthia Kenyon, PhD Department of Biochemistry and Biophysics
Biology with X-ray lasers Robert M. Stroud, PhD Department of Biochemistry and Biophysics
Mechanism of Gene Silencing Hiten D. Madhani, MD, PhD Department of Biochemistry and Biophysics
Integrative Program in Complex Biological System (ipCBS) Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
The Microbiome, Virome and Host Response in Ventilator Associated Pneumonia Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Silver diamine fluoride to treat dental caries Jeremy Horst, DDS, PhD Department of Biochemistry and Biophysics, School of Dentistry
Epigenetic control of virulence in a fungal meningitis pathogen Hiten D. Madhani, MD, PhD Department of Biochemistry and Biophysics
Mapping the conformational cycle of transmembrane transporters Robert M. Stroud, PhD Department of Biochemistry and Biophysics
BRASL - A rapid Barcoded RNA Annealing, Selection, and Ligation assay to detect pathogens. Eric D. Chow, PhD Department of Biochemistry and Biophysics
Molecular Basis for Transmembrane Conduction and Signaling Robert M. Stroud, PhD Department of Biochemistry and Biophysics
A Novel Targeted Therapy for Medulloblastoma Jeremy F. Reiter, MD, PhD Department of Biochemistry and Biophysics
Endothelial Primary Cilia Protect Against Atherosclerosis Jeremy F. Reiter, MD, PhD Department of Biochemistry and Biophysics

Archived Projects: 39

Project Investigator All Organizations Start date
End date
Antibodies to Synaptic Vesicles Regis B. Kelly, MD Department of Biochemistry and Biophysics
A Functional Genomics Approach to Identification of New Anti-Malarial Drug Targets Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
A Genome Wide Characterization of the Erythrocytic Cell Cycle of the Human Parasite Plasmodium Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Novel Anti-Malarials by Combinatorial Pharmacogenomics Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Examination of genome instability in Plasmodium Falciparum using functional genomics Department of Biochemistry and Biophysics
Genomic Technology Development and Infectious Diseases Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
CORE B: Intracellular Pathogens and Innate Immunity Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Proteomic Analysis of Antigenic Switching in the Malaria Parasite Charles C. Kim, PhD Department of Biochemistry and Biophysics
UCDRD Whitepaper: Viral Pathogens Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Development of Anti-Malarial Preclinical Candidates Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Microtubule Nucleation: Structure & Mechanism David A. Agard, PhD Department of Biochemistry and Biophysics
Molecular Engineering of Erythrotropic Bacteria for Treatment and Prevention of Human Malaria Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Integrative Program in Complex Biological System (ipCBS) Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Detection and Discovery of Viral Pathogens Associated with Dengue-like Symptoms in Nicaragua Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Core B: Intracellular Pathogens and Innate Immunity Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Membrane Protein Expression Center Robert M. Stroud, PhD Department of Biochemistry and Biophysics
Mechanisms of gene silencing Hiten D. Madhani, MD, PhD Department of Biochemistry and Biophysics
Development of Proteome-scale Peptide Bead Suspension Arrays for Immunoprofiling and Vaccine Development by Multi Channel Microfludic Flow Sorting. Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Identification of a Viral Pathogen in Nematodes Cynthia Kenyon, PhD Department of Biochemistry and Biophysics
Immunological Detection and Control of Experimental Uncomplicated Malaria Charles C. Kim, PhD Department of Biochemistry and Biophysics
Framework to Address Drug Resistant Infections and Global Health Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Center for the Structure of Membrane Proteins Robert M. Stroud, PhD Department of Biochemistry and Biophysics
Regulation of Virulence of Cryptococcus neoformans Hiten D. Madhani, MD, PhD Department of Biochemistry and Biophysics
Molecular Basis for Transmembrane Conduction and Signaling Robert M. Stroud, PhD Department of Biochemistry and Biophysics
Cryptococcus neoformans Knockout Resource Hiten D. Madhani, MD, PhD Department of Biochemistry and Biophysics
Mechanism of Protein Translocation Across Membranes Peter Walter, PhD Department of Biochemistry and Biophysics
Trans-Synaptic Signaling during Neuromuscular Development Department of Biochemistry and Biophysics
HARC Center: HIV Accessory and Regulatory Complexes Alan D. Frankel, PhD Global Health Sciences Faculty Affiliate, Department of Biochemistry and Biophysics
Structural Basis of Protein Homestasis Peter Walter, PhD Department of Biochemistry and Biophysics
Using Apicoplast-Deficient Parasites to Identify Anti-Malaria Compounds That Specifically Target This Organelle Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Centrosome Structure and the Mechanism of Mt Nucleation by Y-Tubulin Complexes David A. Agard, PhD Department of Biochemistry and Biophysics
Characterization of a Bacteriophage Tubulin Involved in Viral Replication David A. Agard, PhD Department of Biochemistry and Biophysics
Molecular and Cellular Mechanisms of Synaptic Growth Department of Biochemistry and Biophysics
Structure-directed antifungal discovery Robert M. Stroud, PhD Department of Biochemistry and Biophysics
Discovery of Novel Molecular Abnormalities Underlying Non-Lesional Focal Epilepsy Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
High Throughput Screening of Philippine Terrestrial and Marine Organisms for Antimalarial Properties and Identification of Novel Drug Targets Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
High Throughput Screening of Philippine Terrestrial and Marine Organisms for Antimalarial Properties and Identification of Novel Drug Targets Joseph L. Derisi, PhD Department of Biochemistry and Biophysics
Regulation of Virulence of Cryptococcus neoformans Hiten D. Madhani, MD, PhD Department of Biochemistry and Biophysics
Role of SOX2 O-GIcNAcylation in pluripotency Department of Biochemistry and Biophysics